389 research outputs found
Spin wave propagation and spin polarized electron transport in single crystal iron films
The technique of propagating spin wave spectroscopy is applied to a 20 nm
thick Fe/MgO (001) film. The magnetic parameters extracted from the position of
the resonance peaks are very close to those tabulated for bulk iron. From the
propagating waveforms, a group velocity of 4 km/s and an attenuation length of
about 6 micrometers are extracted for 1.6 micrometers-wavelength spin-wave at
18 GHz. From the measured current-induced spin-wave Doppler shift, we also
extract a surprisingly high degree of spin-polarization of the current of 83%.
This set of results makes single-crystalline iron a promising candidate for
building devices utilizing high frequency spin-waves and spin-polarized
currents.Comment: 5 figures, submitted to Phys. Rev.
Uncoupling of p97 ATPase activity has a dominant negative effect on protein extraction
p97 is a highly abundant, homohexameric AAA+ ATPase that performs a variety of essential cellular functions. Characterized as a ubiquitin-selective chaperone, p97 recognizes proteins conjugated to K48-linked polyubiquitin chains and promotes their removal from chromatin and other molecular complexes. Changes in p97 expression or activity are associated with the development of cancer and several related neurodegenerative disorders. Although pathogenic p97 mutations cluster in and around p97's ATPase domains, mutant proteins display normal or elevated ATPase activity. Here, we show that one of the most common p97 mutations (R155C) retains ATPase activity, but is functionally defective. p97-R155C can be recruited to ubiquitinated substrates on chromatin, but is unable to promote substrate removal. As a result, p97-R155C acts as a dominant negative, blocking protein extraction by a similar mechanism to that observed when p97's ATPase activity is inhibited or inactivated. However, unlike ATPase-deficient proteins, p97-R155C consumes excess ATP, which can hinder high-energy processes. Together, our results shed new insight into how pathogenic mutations in p97 alter its cellular function, with implications for understanding the etiology and treatment of p97-associated diseases
Optimal control of motorsport differentials
Modern motorsport limited slip differentials (LSD) have evolved to become highly adjustable, allowing the torque bias that they generate to be tuned in the corner entry, apex and corner exit phases of typical on-track manoeuvres. The task of finding the optimal torque bias profile under such varied vehicle conditions is complex. This paper presents a nonlinear optimal control method which is used to find the minimum time optimal torque bias profile through a lane change manoeuvre. The results are compared to traditional open and fully locked differential strategies, in addition to considering related vehicle stability and agility metrics. An investigation into how the optimal torque bias profile changes with reduced track-tyre friction is also included in the analysis. The optimal LSD profile was shown to give a performance gain over its locked differential counterpart in key areas of the manoeuvre where a quick direction change is required. The methodology proposed can be used to find both optimal passive LSD characteristics and as the basis of a semi-active LSD control algorithm
Random barrier double-well model for resistive switching in tunnel barriers
The resistive switching phenomenon in MgO-based tunnel junctions is
attributed to the effect of charged defects inside the barrier. The presence of
electron traps in the MgO barrier, that can be filled and emptied, locally
modifies the conductance of the barrier and leads to the resistive switching
effects. A double-well model for trapped electrons in MgO is introduced to
theoretically describe this phenomenon. Including the statistical distribution
of potential barrier heights for these traps leads to a power-law dependence of
the resistance as a function of time, under a constant bias voltage. This model
also predicts a power-law relation of the hysteresis as a function of the
voltage sweep frequency. Experimental transport results strongly support this
model and in particular confirm the expected power laws dependencies of
resistance. They moreover indicate that the exponent of these power laws varies
with temperature as theoretically predicted.Comment: 18 pages, 5 figures, final versio
Magneto-optical spectroscopy of (Ga,Mn)N epilayers
We report on the magneto-optical spectroscopy and cathodoluminescence of a
set of wurtzite (Ga,Mn)N epilayers with a low Mn content, grown by molecular
beam epitaxy. The sharpness of the absorption lines associated to the Mn
internal transitions allows a precise study of its Zeeman effect in both
Faraday and Voigt configurations. We obtain a good agreement if we assume a
dynamical Jahn-Teller effect in the 3d configuration of Mn, and we
determine the parameters of the effective Hamiltonians describing the
and levels, and those of the spin Hamiltonian in the
ground spin multiplet, from which the magnetization of the isolated ion can be
calculated. On layers grown on transparent substrates, transmission close to
the band gap, and the associated magnetic circular dichroism, reveal the
presence of the giant Zeeman effect resulting from exchange interactions
between the Mn ions and the carriers. The spin-hole interaction is found
to be ferromagnetic
Procedure for Impact Testing of Fused Recycled Glass
Recycled glass material is made from hundred percent recycled bottle glass and consume less energy than re-melt technology. It also uses no additives in the manufacturing process allowing the recycled glass material, in principal, to go back to the recycling stream after end-of-use, contributing to the circular economy with a low ecological impact.
Previous research with low temperature fused recycled bottle glass was developed for the manufacturing of interior tiles and commissioned by an architectural practice for a new build which was based on sustainable principles. The research considered objective mechanical criteria such as flexural bending strength, stability and stain and scratch resistance. It also emphasized on aesthetic development such as colouring, translucency, texture and reproducibility.
Continuing from previous research results the material is believed to behold properties in which it can be used for other architectural applications such as pavements, wall cladding, or even non-structural furniture. This is a relatively new architectural material of which there has been little publications in material specifications or processes for mechanical testing.
The aim of this paper is to investigate the procedure for testing the recycled glass material for impact resistance, so it can be applied to pavements and other surfaces which are at risk of impact during service. A review of different impact test procedures for construction materials was undertaken, comparing methodologies and international standards applied to other materials such as natural stone, ceramics and glass.
A new drop weight impact testing machine was designed and manufactured in-house to perform these tests. As a case study, samples of the recycled glass material were manufactured with two different thicknesses and tested. The impact energy was calculated theoretically, obtaining results with 5 and 10 Joules. The results on the material were subsequently discussed.
Improvements on the procedure can be made using high speed video technology to calculate velocity just before and immediately after the impact to know the absorbed energy.
The initial results obtained in this procedure were positive although repeatability needs to be developed to obtain a correlation of results and finally be able to validate the procedure. The experiment with samples showed the practicality of this procedure and application to the recycled glass material impact testing although further research needs to be developed
Ariel - Volume 6 Number 1
Editors
John Lammie
Curt Cummings
Frank Chervenak
J.D. Kanofsky
Mark Dembert
Entertainment
Robert Breckenridge
Joe Conti
Gary Kaskey
Photographer
Larry Glazerman
Overseas Editor
Mike Sinason
Circulation
Jay Amsterdam
Humorist
Jim McCann
Staff
Ken Jaffe
Bob Sklaroff
Halley Faus
A General Model for Binary Cell Fate Decision Gene Circuits with Degeneracy: Indeterminacy and Switch Behavior in the Absence of Cooperativity
BACKGROUND: The gene regulatory circuit motif in which two opposing fate-determining transcription factors inhibit each other but activate themselves has been used in mathematical models of binary cell fate decisions in multipotent stem or progenitor cells. This simple circuit can generate multistability and explains the symmetric "poised" precursor state in which both factors are present in the cell at equal amounts as well as the resolution of this indeterminate state as the cell commits to either cell fate characterized by an asymmetric expression pattern of the two factors. This establishes the two alternative stable attractors that represent the two fate options. It has been debated whether cooperativity of molecular interactions is necessary to produce such multistability. PRINCIPAL FINDINGS: Here we take a general modeling approach and argue that this question is not relevant. We show that non-linearity can arise in two distinct models in which no explicit interaction between the two factors is assumed and that distinct chemical reaction kinetic formalisms can lead to the same (generic) dynamical system form. Moreover, we describe a novel type of bifurcation that produces a degenerate steady state that can explain the metastable state of indeterminacy prior to cell fate decision-making and is consistent with biological observations. CONCLUSION: The general model presented here thus offers a novel principle for linking regulatory circuits with the state of indeterminacy characteristic of multipotent (stem) cells
Spin wave study of magnetic perpendicular surface anisotropy in single crystalline MgOFeMgO films
Broadband ferromagnetic resonance is measured in single crystalline Fe films
of varying thickness sandwiched between MgO layers. An exhaustive magnetic
characterization of the films (exchange constant, cubic, uniaxial and surface
anisotropies) is enabled by the study of the uniform and the first
perpendicular standing spin wave modes as a function of applied magnetic field
and film thickness. Additional measurements of non-reciprocal spin wave
propagation allow us to separate each of the two interface contributions to the
total surface anisotropy. The results are consistent with the model of a
quasi-bulk film interior and two magnetically different top and bottom
interfaces, a difference ascribed to different oxidation states
- …