The Rise and Fall of Water Net (Hydrodictyon reticulatum) in New Zealand

During the late 1980s to early 1990s a range of aquatic habitats in the central North Island of New Zealand were invaded by the filamentous green alga, water net Hydrodictyon reticulatum (Linn. Lagerheim). The alga caused significant economic and recreational impacts at major sites of infestation, but it was also associated with enhanced invertebrate numbers and was the likely cause of an improvement in the trout fishery. The causes of prolific growth of water net and the range of control options pursued are reviewed. The possible causes of its sudden decline in 1995 are considered, including physical factors, increase in grazer pressure, disease, and loss of genetic vigour

Questioning ‘what makes us human’: How audiences react to an artificial intelligence–driven show

I am Echoborg is promoted as ‘a show created afresh each time by the audience in conversation with an artificial intelligence (AI)’. The show demonstrates how AI in a creative and performance context can raise questions about the technology’s ethical use for persuasion and compliance, and how humans can reclaim agency. This audience study focuses on a consecutive three-night run in Bristol, UK in October 2019. The different outcomes of each show illustrate the unpredictability of audience interactions with conversational AI and how the collective dynamic of audience members shapes each performance. This study analyses (1) how I am Echoborg facilitates audience cocreation in a live performance context, (2) the show’s capacity to provoke nuanced understandings of the potential for AI and (3) the ability for intelligent technology to facilitate social interaction and group collaboration. This audience study demonstrates how the show inspires debate beyond binary conclusions (i.e. AI as good or bad) and how audiences can understand potential creative uses of AI, including as a tool for cocreating entertainment with (not just for) them

A gauge model for quantum mechanics on a stratified space

In the Hamiltonian approach on a single spatial plaquette, we construct a quantum (lattice) gauge theory which incorporates the classical singularities. The reduced phase space is a stratified K\"ahler space, and we make explicit the requisite singular holomorphic quantization procedure on this space. On the quantum level, this procedure furnishes a costratified Hilbert space, that is, a Hilbert space together with a system which consists of the subspaces associated with the strata of the reduced phase space and of the corresponding orthoprojectors. The costratified Hilbert space structure reflects the stratification of the reduced phase space. For the special case where the structure group is $\mathrm{SU}(2)$, we discuss the tunneling probabilities between the strata, determine the energy eigenstates and study the corresponding expectation values of the orthoprojectors onto the subspaces associated with the strata in the strong and weak coupling approximations.Comment: 38 pages, 9 figures. Changes: comments on the heat kernel and coherent states have been adde

Network development in biological gels: role in lymphatic vessel development

In this paper, we present a model that explains the prepatterning of lymphatic vessel morphology in collagen gels. This model is derived using the theory of two phase rubber material due to Flory and coworkers and it consists of two coupled fourth order partial differential equations describing the evolution of the collagen volume fraction, and the evolution of the proton concentration in a collagen implant; as described in experiments of Boardman and Swartz (Circ. Res. 92, 801–808, 2003). Using linear stability analysis, we find that above a critical level of proton concentration, spatial patterns form due to small perturbations in the initially uniform steady state. Using a long wavelength reduction, we can reduce the two coupled partial differential equations to one fourth order equation that is very similar to the Cahn–Hilliard equation; however, it has more complex nonlinearities and degeneracies. We present the results of numerical simulations and discuss the biological implications of our model

Dynamic Changes in High-Sensitivity Cardiac Troponin I in Response to Anthracycline-Based Chemotherapy

Aims: Treatment advances have improved cancer-related outcomes and shifted interest towards minimising long-term iatrogenic complications, particularly chemotherapy-related cardiotoxicity. High-sensitivity cardiac troponin I (hs-cTnI) assays accurately quantify very low concentrations of plasma troponin and enable early detection of cardiomyocyte injury prior to the development of myocardial dysfunction. The profile of hs-cTnI in response to anthracycline-based treatment has not previously been described. Materials and methods: This was a multicentre prospective observational cohort study. Female patients with newly diagnosed invasive breast cancer scheduled to receive anthracycline-based (epirubicin) chemotherapy were recruited. Blood sampling was carried out before and 24 h after each cycle. Hs-cTnI concentrations were measured using the Abbott ARCHITECTSTAT assay. Results: We recruited 78 women with a median (interquartile range) age of 52 (49–61) years. The median baseline troponin concentration was 1 (1–4) ng/l and the median cumulative epirubicin dose was 394 (300–405) mg/m2. Following an initial 33% fall 24 h after anthracycline dosing (P < 0.001), hs-cTnI concentrations increased by a median of 50% (P < 0.001) with each successive treatment cycle. In total, 45 patients had troponin measured immediately before the sixth treatment cycle, 21 (46.6%) of whom had hs-cTnI concentrations ≥16 ng/l, indicating myocardial injury. Plasma hs-cTnI concentrations before the second treatment cycle were a strong predictor of subsequent myocardial injury. Conclusions: Cardiotoxicity arising from anthracycline therapy is detectable in the earliest stages of breast cancer treatment and is cumulative with each treatment cycle. This injury is most reliably determined from blood sampling carried out before rather than after each treatment cycle

Detecting Microscopic Black Holes with Neutrino Telescopes

If spacetime has more than four dimensions, ultra-high energy cosmic rays may create microscopic black holes. Black holes created by cosmic neutrinos in the Earth will evaporate, and the resulting hadronic showers, muons, and taus may be detected in neutrino telescopes below the Earth's surface. We simulate such events in detail and consider black hole cross sections with and without an exponential suppression factor. We find observable rates in both cases: for conservative cosmogenic neutrino fluxes, several black hole events per year are observable at the IceCube detector; for fluxes at the Waxman-Bahcall bound, tens of events per year are possible. We also present zenith angle and energy distributions for all three channels. The ability of neutrino telescopes to differentiate hadrons, muons, and possibly taus, and to measure these distributions provides a unique opportunity to identify black holes, to experimentally constrain the form of black hole production cross sections, and to study Hawking evaporation.Comment: 20 pages, 9 figure

Spatio-temporal genetic tagging of a cosmopolitan planktivorous shark provides insight to gene flow, temporal variation and site-specific re-encounters

Migratory movements in response to seasonal resources often influence population structure and dynamics. Yet in mobile marine predators, population genetic consequences of such repetitious behaviour remain inaccessible without comprehensive sampling strategies. Temporal genetic sampling of seasonally recurring aggregations of planktivorous basking sharks, Cetorhinus maximus, in the Northeast Atlantic (NEA) affords an opportunity to resolve individual re-encounters at key sites with population connectivity and patterns of relatedness. Genetic tagging (19 microsatellites) revealed 18% of re-sampled individuals in the NEA demonstrated inter/multi-annual site-specific re-encounters. High genetic connectivity and migration between aggregation sites indicate the Irish Sea as an important movement corridor, with a contemporary effective population estimate (Ne) of 382 (CI = 241–830). We contrast the prevailing view of high gene flow across oceanic regions with evidence of population structure within the NEA, with early-season sharks off southwest Ireland possibly representing genetically distinct migrants. Finally, we found basking sharks surfacing together in the NEA are on average more related than expected by chance, suggesting a genetic consequence of, or a potential mechanism maintaining, site-specific re-encounters. Long-term temporal genetic monitoring is paramount in determining future viability of cosmopolitan marine species, identifying genetic units for conservation management, and for understanding aggregation structure and dynamics

CP Violation in Fermion Pair Decays of Neutral Boson Particles

We study CP violation in fermion pair decays of neutral boson particles with spin 0 or 1. We study a new asymmetry to measure CP violation in $\eta, K_L \rightarrow \mu^+\mu^-$ decays and discuss the possibility of measuring it experimentally. For the spin-1 particles case, we study CP violation in the decays of $J/\psi$ to $SU(3)$ octet baryon pairs. We show that these decays can be used to put stringent constraints on the electric dipole moments of $\Lambda$, $\Sigma$ and $\Xi$.Comment: 14p, OZ-93/22, UM-93/89, OITS 51

Black Holes from Cosmic Rays: Probes of Extra Dimensions and New Limits on TeV-Scale Gravity

If extra spacetime dimensions and low-scale gravity exist, black holes will be produced in observable collisions of elementary particles. For the next several years, ultra-high energy cosmic rays provide the most promising window on this phenomenon. In particular, cosmic neutrinos can produce black holes deep in the Earth's atmosphere, leading to quasi-horizontal giant air showers. We determine the sensitivity of cosmic ray detectors to black hole production and compare the results to other probes of extra dimensions. With n \ge 4 extra dimensions, current bounds on deeply penetrating showers from AGASA already provide the most stringent bound on low-scale gravity, requiring a fundamental Planck scale M_D > 1.3 - 1.8 TeV. The Auger Observatory will probe M_D as large as 4 TeV and may observe on the order of a hundred black holes in 5 years. We also consider the implications of angular momentum and possible exponentially suppressed parton cross sections; including these effects, large black hole rates are still possible. Finally, we demonstrate that even if only a few black hole events are observed, a standard model interpretation may be excluded by comparison with Earth-skimming neutrino rates.Comment: 30 pages, 18 figures; v2: discussion of gravitational infall, AGASA and Fly's Eye comparison added; v3: Earth-skimming results modified and strengthened, published versio

The CLIMPACTS synthesis report: An assessment of the effects of climate change and variation in New Zealand using the CLIMPACTS system

In the late 1980s, New Zealand undertook the first national assessment of climate change and its possible impacts on the country.The landmark report, reflecting the judgement of scores of national experts, called for greater efforts in building the national research capacity in order to better quantify the range of impacts that could occur in New Zealand from climate change and variability. In response, the collaborative CLIMPACTS Programme was established to provide this capacity. Ten years on from the first national assessment, the present synthesis offers some results from, as well as a demonstration of, the capacity developed by the CLIMPACTS Programme. The purpose of the present document is to provide a summary report from the CLIMPACTS Programme on climate change and its effects on New Zealand.The chapters and their contents are not comprehensive. Rather, they are focused on a specific set of questions, which conform to the particular expertise of the CLIMPACTS Programme members and which employ a limited set of the wide range of tools available within the CLIMPACTS Model. Other important areas such as forests, indigenous ecosystems and pests and diseases are not yet covered