Modeling Partially Reliable Information Sources: A General Approach Based on Dempster-Shafer Theory

Combining testimonial reports from independent and partially reliable information sources is an important problem of uncertain reasoning. Within the framework of Dempster-Shafer theory, we propose a general model of partially reliable sources which includes several previously known results as special cases. The paper reproduces these results, gives a number of new insights, and thereby contributes to a better understanding of this important application of reasoning with uncertain and incomplete information.Articl

Cast-as-Intended Mechanism with Return Codes Based on PETs

We propose a method providing cast-as-intended verifiability for remote electronic voting. The method is based on plaintext equivalence tests (PETs), used to match the cast ballots against the pre-generated encrypted code tables. Our solution provides an attractive balance of security and functional properties. It is based on well-known cryptographic building blocks and relies on standard cryptographic assumptions, which allows for relatively simple security analysis. Our scheme is designed with a built-in fine-grained distributed trust mechanism based on threshold decryption. It, finally, imposes only very little additional computational burden on the voting platform, which is especially important when voters use devices of restricted computational power such as mobile phones. At the same time, the computational cost on the server side is very reasonable and scales well with the increasing ballot size

First Demonstration of a Pixelated Charge Readout for Single-Phase Liquid Argon Time Projection Chambers

Liquid Argon Time Projection Chambers (LArTPCs) have been selected for the future long-baseline Deep Underground Neutrino Experiment (DUNE). To allow LArTPCs to operate in the high-multiplicity near detector environment of DUNE, a new charge readout technology is required. Traditional charge readout technologies introduce intrinsic ambiguities, combined with a slow detector response, these ambiguities have limited the performance of LArTPCs, until now. Here, we present a novel pixelated charge readout that enables the full 3D tracking capabilities of LArTPCs. We characterise the signal to noise ratio of charge readout chain, to be about 14, and demonstrate track reconstruction on 3D space points produced by the pixel readout. This pixelated charge readout makes LArTPCs a viable option for the DUNE near detector complex.Comment: 13 pages, 9 figure

Nano-particle vaccination combined with TLR-7 and -9 ligands triggers memory and effector CD8⁺ T-cell responses in melanoma patients.

Optimal vaccine strategies must be identified for improving T-cell vaccination against infectious and malignant diseases. MelQbG10 is a virus-like nano-particle loaded with A-type CpG-oligonucleotides (CpG-ODN) and coupled to peptide(16-35) derived from Melan-A/MART-1. In this phase IIa clinical study, four groups of stage III-IV melanoma patients were vaccinated with MelQbG10, given (i) with IFA (Montanide) s.c.; (ii) with IFA s.c. and topical Imiquimod; (iii) i.d. with topical Imiquimod; or (iv) as intralymph node injection. In total, 16/21 (76%) patients generated ex vivo detectable Melan-A/MART-1-specific T-cell responses. T-cell frequencies were significantly higher when IFA was used as adjuvant, resulting in detectable T-cell responses in all (11/11) patients, with predominant generation of effector-memory-phenotype cells. In turn, Imiquimod induced higher proportions of central-memory-phenotype cells and increased percentages of CD127(+) (IL-7R) T cells. Direct injection of MelQbG10 into lymph nodes resulted in lower T-cell frequencies, associated with lower proportions of memory and effector-phenotype T cells. Swelling of vaccine site draining lymph nodes, and increased glucose uptake at PET/CT was observed in 13/15 (87%) of evaluable patients, reflecting vaccine triggered immune reactions in lymph nodes. We conclude that the simultaneous use of both Imiquimod and CpG-ODN induced combined memory and effector CD8(+) T-cell responses

Power tests of a string of magnets comprising a full cell of the Superconducting Super Collider

In this paper we describe the operation and testing of a string of magnets comprising a full cell of the Superconducting Super Collider (SSC). The full cell configuration composed of ten dipoles, two quadrupoles, and three spool pieces is the longest SSC magnet string ever tested. Although the tests of the full cell were undertaken after the SSC project was marked for termination, their completion was deemed necessary and useful to future efforts at other accelerator laboratories utilizing Superconducting magnets. The focus of this work is on the electrical and cryogenic performance of the string components and the quench protection system with an emphasis on solving some of the questions concerning electrical performance raised during the previous two experimental runs involving a half cell configuration

Long-Baseline Neutrino Facility (LBNF) and Deep Underground Neutrino Experiment (DUNE) Conceptual Design Report Volume 2: The Physics Program for DUNE at LBNF

The Physics Program for the Deep Underground Neutrino Experiment (DUNE) at the Fermilab Long-Baseline Neutrino Facility (LBNF) is described

Pride and popcorn: consuming the idea of community at film screenings in the Turkish diaspora

A range of studies have revealed the interrelatedness of identity construction, community formation and media among diasporas, mostly focusing on domestic contexts. Seeking to add further nuance to the understanding of the social lives of diasporas, we concentrate on media culture in the public environment of the film theatre. The significance of diasporic film consumption is investigated through a local audience study of Turkish film screenings in Antwerp. The phenomenon of the screenings was analysed through a multi-method approach, including 536 questionnaires among audiences, 19 in-depth interviews and 3 group interviews, along with previous findings (on distribution and exploitation) of the same project. The results show that Turkish films are almost exclusively attended by people with Turkish roots, creating a Turkish diasporic space within the boundaries of the urban and the public. The audience study shows that the screenings fulfil a major social role but also affect understandings of community