232 research outputs found

    Health and safety: Preliminary comparative assessment of the Satellite Power System (SPS) and other energy alternatives

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    Data readily available from the literature were used to make an initial comparison of the health and safety risks of a fission power system with fuel reprocessing; a combined-cycle coal power system with a low-Btu gasifier and open-cycle gas turbine; a central-station, terrestrial, solar photovoltaic power system; the satellite power system; and a first-generation fusion system. The assessment approach consists of the identification of health and safety issues in each phase of the energy cycle from raw material extraction through electrical generation, waste disposal, and system deactivation; quantitative or qualitative evaluation of impact severity; and the rating of each issue with regard to known or potential impact level and level of uncertainty

    Comparative health and safety assessment of the SPS and alternative electrical generation systems

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    A comparative analysis of health and safety risks is presented for the Satellite Power System and five alternative baseload electrical generation systems: a low-Btu coal gasification system with an open-cycle gas turbine combined with a steam topping cycle; a light water fission reactor system without fuel reprocessing; a liquid metal fast breeder fission reactor system; a central station terrestrial photovoltaic system; and a first generation fusion system with magnetic confinement. For comparison, risk from a decentralized roof-top photovoltaic system with battery storage is also evaluated. Quantified estimates of public and occupational risks within ranges of uncertainty were developed for each phase of the energy system. The potential significance of related major health and safety issues that remain unquantitied are also discussed

    Assessment of a satellite power system and six alternative technologies

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    The satellite power system is assessed in comparison to six alternative technologies. The alternatives are: central-station terrestrial photovoltaic systems, conventional coal-fired power plants, coal-gasification/combined-cycle power plants, light water reactor power plants, liquid-metal fast-breeder reactors, and fusion. The comparison is made regarding issues of cost and performance, health and safety, environmental effects, resources, socio-economic factors, and institutional issues. The criteria for selecting the issues and the alternative technologies are given, and the methodology of the comparison is discussed. Brief descriptions of each of the technologies considered are included

    No singular modulus is a unit

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    A result of the second-named author states that there are only finitely many CM-elliptic curves over C\mathbb{C} whose jj-invariant is an algebraic unit. His proof depends on Duke's Equidistribution Theorem and is hence non-effective. In this article, we give a completely effective proof of this result. To be precise, we show that every singular modulus that is an algebraic unit is associated with a CM-elliptic curve whose endomorphism ring has discriminant less than 101510^{15}. Through further refinements and computer-assisted computations, we eventually rule out all remaining cases, showing that no singular modulus is an algebraic unit. This allows us to exhibit classes of subvarieties in Cn\mathbb{C}^n not containing any special points.Comment: Dedicated to David Masser on the occasion of his 70th birthday. Version 2 has a new title, updated references, and contains minor corrections. 31 pages, to appear in IMRN. Link to scripts https://github.com/philipphabegger/Effective-Bounds-for-Singular-Unit

    EFFECT OF POLYMORPHISM ON EXPRESSION OF THE NEUROPEPTIDE Y GENE IN INBRED ALCOHOL-PREFERRING AND -NONPREFERRING RATS

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    Using animal models of alcoholism, previous studies suggest that neuropeptide Y (NPY) may be implicated in alcohol preference and consumption due to its role in the modulation of feeding and anxiety. Quantitative trait loci (QTL) analysis previously identified an interval on rat chromosome 4 that is highly associated with alcohol preference and consumption using an F2 population derived from inbred alcohol-preferring (iP) and -nonpreferring (iNP) rats. NPY mapped to the peak of this QTL region and was prioritized as a candidate gene for alcohol-seeking behavior in the iP and iNP rats. In order to identify a potential mechanism for reduced NPY protein levels documented in the iP rat, genetic and molecular components that influence NPY expression were analyzed between iP and iNP rats. Comparing the iP rat to the iNP rat, quantitative real-time polymerase chain reaction detected significantly decreased levels of NPY mRNA expression in the iP rat in the six brain regions tested: nucleus accumbens, frontal cortex, amygdala, hippocampus, caudate-putamen, and hypothalamus. In addition, the functional significance of three previously identified polymorphisms was assessed using in vitro expression analysis. The polymorphism defined by microsatellite marker D4Mit7 in iP rats reduced luciferase reporter gene expression in SK-N-SH neuroblastoma cells. These results suggest that differential expression of the NPY gene resulting from the D4mit7 marker polymorphism may contribute to reduced levels of NPY in discrete brain regions in the iP rats

    Diassociative algebras and Milnor's invariants for tangles

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    We extend Milnor's mu-invariants of link homotopy to ordered (classical or virtual) tangles. Simple combinatorial formulas for mu-invariants are given in terms of counting trees in Gauss diagrams. Invariance under Reidemeister moves corresponds to axioms of Loday's diassociative algebra. The relation of tangles to diassociative algebras is formulated in terms of a morphism of corresponding operads.Comment: 17 pages, many figures; v2: several typos correcte

    Methodology for the comparative assessment of the Satellite Power System (SPS) and alternative technologies

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    The energy systems concerned are the satellite power system, several coal technologies, geothermal energy, fission, fusion, terrestrial solar systems, and ocean thermal energy conversion. Guidelines are suggested for the characterization of these systems, side-by-side analysis, alternative futures analysis, and integration and aggregation of data. A description of the methods for assessing the technical, economic, environmental, societal, and institutional issues surrounding the development of the selected energy technologies is presented

    Analysis of variable retroduplications in human populations suggests coupling of retrotransposition to cell division

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    In primates and other animals, reverse transcription of mRNA followed by genomic integration creates retroduplications. Expressed retroduplications are either “retrogenes” coding for functioning proteins, or expressed “processed pseudogenes,” which can function as noncoding RNAs. To date, little is known about the variation in retroduplications in terms of their presence or absence across individuals in the human population. We have developed new methodologies that allow us to identify “novel” retroduplications (i.e., those not present in the reference genome), to find their insertion points, and to genotype them. Using these methods, we catalogued and analyzed 174 retroduplication variants in almost one thousand humans, which were sequenced as part of Phase 1 of The 1000 Genomes Project Consortium. The accuracy of our data set was corroborated by (1) multiple lines of sequencing evidence for retroduplication (e.g., depth of coverage in exons vs. introns), (2) experimental validation, and (3) the fact that we can reconstruct a correct phylogenetic tree of human subpopulations based solely on retroduplications. We also show that parent genes of retroduplication variants tend to be expressed at the M-to-G1 transition in the cell cycle and that M-to-G1 expressed genes have more copies of fixed retroduplications than genes expressed at other times. These findings suggest that cell division is coupled to retrotransposition and, perhaps, is even a requirement for it
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