Relevance of Donation to Special Federal Tertiary Institution Libraries in Zaria, Kaduna State

This paper examine the relevance of donations to Special Federal Tertiary Institution Libraries in Zaria, Kaduna State, the objectives of the study are: to find out the donor agencies available to the libraries; the donations given to the libraries and to find out how relevant are the donation from the donors. The study adopted qualitative research approach. While structured and open-ended interview and relevant documents, including giftand donation files, acquisition records and library accession registers were used to collect data for the study. The population of the study consisted of the Special Federal Tertiary Institution Libraries under study while thesubjects of the study were the 41 staff, which included the institutions’ librarians (Liaison Officers) and the resources development unit library staff of each library. Descriptive statistical tools were used to analyze and present the data. The study discovered that the most donated resources to the libraries were books and journals; the findings also revealed that, though all the special federal tertiary institution libraries have one type of donor or the other, they mostly benefit from individual and corporate donors and also most of these resources were current but irrelevant, while those that were relevant were not sufficient to meet the needs of the libraries. In the light of the findings of the study, it was concluded that the special federal tertiary institution libraries studied were inadequately funded, thus, the libraries have sought for an alternative means in terms of donation to support or augment the major source of fund for library resource development, which has contributed positively but not sufficiently to the development of the library. The study recommended among others that, there is need for the government to increase library annual allocation to avoid problem of inadequate funds. And there is a need for those libraries under study to seek for support from local donors such as Nigerian Book Foundation (NBF), Sir Emeka Offor Foundation (SEOF) that could contribute financially or other wise to their library; Donors should try to donate relevant resources to libraries this can be done by seeking advice from a professional librarian

Influence of the initial chemical conditions on the rational design of silica particles

The influence of the water content in the initial composition on the size of silica particles produced using the Stöber process is well known. We have shown that there are three morphological regimes defined by compositional boundaries. At low water levels (below stoichiometric ratio of water:tetraethoxysilane), very high surface area and aggregated structures are formed; at high water content (>40 wt%) similar structures are also seen. Between these two boundary conditions, discrete particles are formed whose size are dictated by the water content. Within the compositional regime that enables the classical Stöber silica, the structural evolution shows a more rapid attainment of final particle size than the rate of formation of silica supporting the monomer addition hypothesis. The clearer understanding of the role of the initial composition on the output of this synthesis method will be of considerable use for the establishment of reliable reproducible silica production for future industrial adoption

Prevalence of Vaginal Candidiasis among Pregnant Women with Abnormal Vaginal Discharge in Maiduguri

BACKGROUND: Pregnancy represents a risk factor in the occurrence of vaginal candidiasis. OBJECTIVES: To determine the prevalence and clinical features associated with abnormal vaginal discharge and C. albicans infection in pregnant women.METHODS: High vaginal swab samples and data on epidemiological characteristics were collected from 400 pregnant women with complaints of abnormal vaginal discharge at booking clinic of University of Maiduguri Teaching Hospital. The data was analysed using SPSS 16.0 statistical software.RESULTS: The prevalence of abnormal vaginal discharge in pregnancy was 31.5%. The frequency of abnormal vaginal discharge was 183 (45.8%) among those aged 20-24 years, 291 (72.8%) in multipara, 223 (55.8%) in those with Primary education and 293 (73.2%) in unemployed. Vulval pruritus 300 (75.0%) was significantly related to abnormal vaginal discharge (P<0.001). The prevalence of C. albicans was 41%. The frequencies of Vulval itching, Dyspareunia and vulval excoriation among those with candidiasis were 151 (50.3%), 14 (56.0%) and 75 (75.0%) respectively (P<0.001). CONCLUSION: The prevalence of abnormal vaginal discharge in pregnancy was high in this study and C. albicans was the commonest cause. It is recommended that a pregnant woman complaining of abnormal vaginal discharge be assessed and Laboratory diagnosis done in order to give appropriate treatment. Erratum Note: Ibrahim SM, Mohammed B, Yahaya M, Audu BM, Ibrahim HA on the article ”Prevalence of VaginalCandidiasis among Pregnant Women with Abnormal Vaginal Discharge in Maiduguri” on Page Nig. J. Med2013. 138-142. Should read: Ibrahim SM, Bukar M, Mohammed Y, Audu BM, Ibrahim HM

SCAMP:standardised, concentrated, additional macronutrients, parenteral nutrition in very preterm infants: a phase IV randomised, controlled exploratory study of macronutrient intake, growth and other aspects of neonatal care

<p>Abstract</p> <p>Background</p> <p>Infants born <29 weeks gestation are at high risk of neurocognitive disability. Early postnatal growth failure, particularly head growth, is an important and potentially reversible risk factor for impaired neurodevelopmental outcome. Inadequate nutrition is a major factor in this postnatal growth failure, optimal protein and calorie (macronutrient) intakes are rarely achieved, especially in the first week. Infants <29 weeks are dependent on parenteral nutrition for the bulk of their nutrient needs for the first 2-3 weeks of life to allow gut adaptation to milk digestion. The prescription, formulation and administration of neonatal parenteral nutrition is critical to achieving optimal protein and calorie intake but has received little scientific evaluation. Current neonatal parenteral nutrition regimens often rely on individualised prescription to manage the labile, unpredictable biochemical and metabolic control characteristic of the early neonatal period. Individualised prescription frequently fails to translate into optimal macronutrient delivery. We have previously shown that a standardised, concentrated neonatal parenteral nutrition regimen can optimise macronutrient intake.</p> <p>Methods</p> <p>We propose a single centre, randomised controlled exploratory trial of two standardised, concentrated neonatal parenteral nutrition regimens comparing a standard macronutrient content (maximum protein 2.8 g/kg/day; lipid 2.8 g/kg/day, dextrose 10%) with a higher macronutrient content (maximum protein 3.8 g/kg/day; lipid 3.8 g/kg/day, dextrose 12%) over the first 28 days of life. 150 infants 24-28 completed weeks gestation and birthweight <1200 g will be recruited. The primary outcome will be head growth velocity in the first 28 days of life. Secondary outcomes will include a) auxological data between birth and 36 weeks corrected gestational age b) actual macronutrient intake in first 28 days c) biomarkers of biochemical and metabolic tolerance d) infection biomarkers and other intravascular line complications e) incidence of major complications of prematurity including mortality f) neurodevelopmental outcome at 2 years corrected gestational age</p> <p>Trial registration</p> <p>Current controlled trials: <a href="http://www.controlled-trials.com/ISRCTN76597892">ISRCTN76597892</a>; EudraCT Number: 2008-008899-14</p

Inter-hemispheric EEG coherence analysis in Parkinson's disease : Assessing brain activity during emotion processing

Parkinson’s disease (PD) is not only characterized by its prominent motor symptoms but also associated with disturbances in cognitive and emotional functioning. The objective of the present study was to investigate the influence of emotion processing on inter-hemispheric electroencephalography (EEG) coherence in PD. Multimodal emotional stimuli (happiness, sadness, fear, anger, surprise, and disgust) were presented to 20 PD patients and 30 age-, education level-, and gender-matched healthy controls (HC) while EEG was recorded. Inter-hemispheric coherence was computed from seven homologous EEG electrode pairs (AF3–AF4, F7–F8, F3–F4, FC5–FC6, T7–T8, P7–P8, and O1–O2) for delta, theta, alpha, beta, and gamma frequency bands. In addition, subjective ratings were obtained for a representative of emotional stimuli. Interhemispherically, PD patients showed significantly lower coherence in theta, alpha, beta, and gamma frequency bands than HC during emotion processing. No significant changes were found in the delta frequency band coherence. We also found that PD patients were more impaired in recognizing negative emotions (sadness, fear, anger, and disgust) than relatively positive emotions (happiness and surprise). Behaviorally, PD patients did not show impairment in emotion recognition as measured by subjective ratings. These findings suggest that PD patients may have an impairment of inter-hemispheric functional connectivity (i.e., a decline in cortical connectivity) during emotion processing. This study may increase the awareness of EEG emotional response studies in clinical practice to uncover potential neurophysiologic abnormalities

Phytochemical composition and toxicity of the aqueous extract of Parkia biglobosa pods in adult Clarias gariepinus

The phytochemical composition and toxicological evaluation of the aqueous extract of Parkia biglobosa pods in adult Clarias gariepinus was investigated over a 96-h exposure period. The aqueous extract of the pods was freeze-dried and screened for its phytochemical constituents. This revealed the presence of glycosides, alkaloids, saponins, steroids and triterpenes, tannins, carbohydrates and flavonoids but no anthraquinones and fixed oils. The fish were exposed to varying concentrations of the extract in a static acute toxicity bioassay. The exposed fish showed initial signs of agitated and erratic movements followed by signs of respiratory distress and abnormal nervous compromise, including mortality in some of the exposed fish. No such obvious signs of toxicity were recorded in the unexposed control fish. The appearance and intensity of the signs were both concentrations and exposure period-dependent. Mean mortality was significantly (p&lt;0.05) related to extract concentrations and exposure period. The median lethal concentration of the extract in exposed fish over the 96-h exposure period was calculated to be 115.38 mg/l. Parkia biglobosa pods contained some toxicologically active constituents that can be meaningfully exploited to harvest fish from water bodies. However, this should be done with great care as the abusive use (higher concentrations) of this extract could result in extract residues in the exposed fish that might pose a risk to the consumers of such fish.Keywords: Clarias gariepinus, Parkia biglobosa pods, phytochemical constituents, toxicity

A recent trend of drug-nanoparticles in suspension for the application in drug delivery

Persistent development in nanomedicine has enabled successful nanosizing of most drug samples which, in turn, imparts remarkable properties to the drugs such as enhanced solubility and bioavailability for the applications in drug delivery In this context several review articles are available in scientific domain covering inorganic nanoparticles such as Au Ag, SPIONs Qdots, carbon nanotubes and graphene; however, this review covers the development of drug nanoparticles together with their possibilities and limitation from ..

Radiation protection: an initial assessment of level of knowledge and compliance amongst radiation workers in ahmadu bello university teaching hospital Zaria, Nigeria

Medical use of ionizing radiation can result to deleterious effects such as undesirable somatic and genetic modifications, although less radiation dose is involved in diagnostic radiology. This necessitates the need for radiation safety practices, to bring to the barest minimum possibility of these risks. This study was aimed at assessing the knowledge and radiation safety practices amongst radiation workers in Ahmadu Bello University Teaching Hospital(ABUTH) Zaria, Nigeria. Method: The study was conducted amongst radiologist, radiology resident doctors, radiographers, nurses, and technicians, with the use of questionnaire for assessment of knowledge, attitude and covert monitoring of personnel for assessment of implementation. Data was analyzed with Statistical Package for Social Sciences (SPSS) for Windows® version 20. Results: Assessment of knowledge was quite impressive with average score 91% and 78% for the radiologists/residents and the radiographers respectively, while the group of “Others” (i.e. nurses and technician) was abysmal with a score 42%. Radiation protection gadgets were either lacking or obsolete. Application of shielding devices such as gonad shield for protection and thermoluminiscent devices (TLDs) were neglected by about 56% of the personnel. The x-ray imaging machines were quite old with no quality assurance tests performed for quite some time. Conclusion: Excellent knowledge of radiation protection was exhibited by the majority of radiation workers in ABUTH, though from self-efforts. However, compliance with the standard radiation protection guidelines is appalling. The need for improved and sustained efforts by both the management and the personnel in radiation protection can never be over emphasized in order to avoid deleterious effects of radiation on both the personnel and patients

Intra-colonial Population of Macrotermes bellicosus (Smeathman) [Isoptera: Termitidae] in Sokoto, Semi-Arid Zone of North-Western Nigeria

The intra- colonial population of individuals within the mounds of mound- building termite, Macrotermes bellicosus (Smeathman) occurring in some selected Local Government Areas of Sokoto State were studied. A total of 72 cone shaped mounds were selected based on their heights. Populationswere estimated by randomly collecting and counting core samples from the mounds using a small bucket as the mounds were being excavated. At the end of the excavation, the total sand removed from the mound was crushed and measured using the same bucket. Total number of termites from a mound was extrapolated from the above estimates. Results indicate the presence of five different castes; reproductives, workers, minor and major soldiers and nymphs. The population of individuals per moundapart from the reproductives, ranged between 14158.00 and 24777.67 with an average of 18,795.49 termites per mound. The nymphs were the largest (5,942.60) closely followed by the workers (5,547.70), while the minor soldiers are the least with 3,279.38. Significant difference (p&lt;0.05) occurred between minor soldiers and nymphs, major soldiers and nymphs, minor soldiers and workers and minor soldiers and nymphs in some of the studied areas. The present study show M. bellicosus to have high population within individual mounds enough to cause damage if ignored. Being a pestiferous species that could promote erosion, appropriate control strategies are required for its control.Key words: Macrotermes bellicosus, Mounds- building termites, intra-colonial Population, Mounds, Castes

Psoriatic Arthritis and Burden of Disease: Patient Perspectives from the Population-Based Multinational Assessment of Psoriasis and Psoriatic Arthritis (MAPP) Survey

Introduction: Psoriatic arthritis (PsA) is underdiagnosed and has a substantial impact on quality of life, disability, and work productivity. The population-based Multinational Assessment of Psoriasis and Psoriatic Arthritis (MAPP) survey examined the impact of PsA on patients’ activities of daily living and unmet treatment needs. Methods: This large-scale, random digit dialing, telephone survey of patients self-reporting a diagnosis of psoriasis and/or PsA was conducted in North America and Europe. Results: In all, 3426 patients participated in the survey, including 712 (21%) who identified themselves as having PsA. Over half of the patients reported severe PsA involving more than four joints. Eighty-three percent of patients with PsA visited a health-care provider within the past 12 months. Approximately one-quarter saw their primary care provider or dermatologist most often for their disease; 37% responded that their rheumatologist was the health-care provider seen most often for PsA. Patients with PsA reported a substantial impact of disease on physical function. One-third of patients with PsA reported missing work because of their disease and PsA impacted their ability to work full time. Over half of the patients with PsA (58%) reported receiving no treatment or topical therapy only, leaving their joint disease untreated. Factors associated with lack of adherence were perceived lack of efficacy and concerns about long-term safety. Conclusions: The MAPP survey confirms that PsA has a significant impact on physical function and activities of daily living. Undertreatment of PsA suggests a need for improved screening and diagnosis as well as education about treatment options and adherence