Failing to ignore: Paradoxical neural effects of perceptual load on early attentional selection in normal aging

We examined visual selective attention under perceptual load - simultaneous presentation of task-relevant and -irrelevant information - in healthy young and older adult human participants to determine whether age differences are observable at early stages of selection in the visual cortices. Participants viewed 50/50 superimposed face/place images and judged whether the faces were male or female, rendering places perceptible but task-irrelevant. Each stimulus was repeated, allowing us to index dynamic stimulus-driven competition from places. Consistent with intact early selection in young adults, we observed no adaptation to unattended places in parahippocampal place area (PPA) and significant adaptation to attended faces in fusiform face area (FFA). Older adults, however, exhibited both PPA adaptation to places and weak FFA adaptation to faces. We also probed participants\u27 associative recognition for face-place pairs post-task. Older adults with better place recognition memory scores were found to exhibit both the largest magnitudes of PPA adaptation and the smallest magnitudes of FFA adaptation on the attention task. In a control study, we removed the competing perceptual information to decrease perceptual load. These data revealed that the initial age-related impairments in selective attention were not due to a general decline in visual cortical selectivity; both young and older adults exhibited robust FFA adaptation and neither group exhibited PPA adaptation to repeated faces. Accordingly, distracting information does not merely interfere with attended input in older adults, but is co-encoded along with the contents of attended input, to the extent that this information can subsequently be recovered from recognition memory. Copyright © 2010 the authors

Energy Momentum Tensor and Marginal Deformations in Open String Field Theory

Marginal boundary deformations in a two dimensional conformal field theory correspond to a family of classical solutions of the equations of motion of open string field theory. In this paper we develop a systematic method for relating the parameter labelling the marginal boundary deformation in the conformal field theory to the parameter labelling the classical solution in open string field theory. This is done by first constructing the energy-momentum tensor associated with the classical solution in open string field theory using Noether method, and then comparing this to the answer obtained in the conformal field theory by analysing the boundary state. We also use this method to demonstrate that in open string field theory the tachyon lump solution on a circle of radius larger than one has vanishing pressure along the circle direction, as is expected for a codimension one D-brane.Comment: LaTeX file, 25 pages; v2: minor addition

Twist Symmetry and Classical Solutions in Open String Field Theory

We construct classical solutions of open string field theory which are not invariant under ordinary twist operation. From detailed analysis of the moduli space of the solutions, it turns out that our solutions become nontrivial at boundaries of the moduli space. The cohomology of the modified BRST operator and the CSFT potential evaluated by the level truncation method strongly support the fact that our nontrivial solutions correspond to the closed string vacuum. We show that the nontrivial solutions are equivalent to the twist even solution which was found by Takahashi and Tanimoto, and twist invariance of open string field theory remains after the shift of the classical backgrounds.Comment: 19 pages, 2 figures; v2: errors fixe

Dynamics with Infinitely Many Derivatives: The Initial Value Problem

Differential equations of infinite order are an increasingly important class of equations in theoretical physics. Such equations are ubiquitous in string field theory and have recently attracted considerable interest also from cosmologists. Though these equations have been studied in the classical mathematical literature, it appears that the physics community is largely unaware of the relevant formalism. Of particular importance is the fate of the initial value problem. Under what circumstances do infinite order differential equations possess a well-defined initial value problem and how many initial data are required? In this paper we study the initial value problem for infinite order differential equations in the mathematical framework of the formal operator calculus, with analytic initial data. This formalism allows us to handle simultaneously a wide array of different nonlocal equations within a single framework and also admits a transparent physical interpretation. We show that differential equations of infinite order do not generically admit infinitely many initial data. Rather, each pole of the propagator contributes two initial data to the final solution. Though it is possible to find differential equations of infinite order which admit well-defined initial value problem with only two initial data, neither the dynamical equations of p-adic string theory nor string field theory seem to belong to this class. However, both theories can be rendered ghost-free by suitable definition of the action of the formal pseudo-differential operator. This prescription restricts the theory to frequencies within some contour in the complex plane and hence may be thought of as a sort of ultra-violet cut-off.Comment: 40 pages, no figures. Added comments concerning fractional operators and the implications of restricting the contour of integration. Typos correcte

A remark on non-Abelian classical kinetic theory

It is known that non-Abelian classical kinetic theory reproduces the Hard Thermal/Dense Loop (HTL/HDL) effective action of QCD, obtained after integrating out the hardest momentum scales from the system, as well as the first higher dimensional operator beyond the HTL/HDL level. We discuss here its applicability at still higher orders, by comparing the exact classical effective action obtained in the static limit, with the 1-loop quantum effective potential. We remark that while correct types of operators arise, the classical colour algebra reproduces correctly the prefactor of the 4-point function $tr A_0^4$ only for matter in asymptotically high dimensional colour representations.Comment: 6 page

The Distribution and Origins of Ancient Leprosy

Human leprosy is primarily caused by Mycobacterium leprae, but also by the related ‘M. lepromatosis’. Ancient leprosy can be recognised in archaeological materials by the paleopathology associated with multi-bacillary or lepromatous forms of the disease. Whole M. leprae genomes have been obtained from human skeletons, and diagnostic aDNA fragments have been recovered. The derived M. leprae phylogenies, based on single nucleotide polymorphisms, mirror past human migrations, as M. leprae is usually an obligate pathogen. The detection of M. leprae in historical leprosy cases is assisted by the hydrophobic M. leprae cell envelope, which is composed of unusual lipids that can be used as specific biomarkers. Lipid biomarkers are more stable than aDNA and can be detected directly without amplification. Indigenous human leprosy is extinct in Western Europe, but recently, both M. leprae and ‘M. lepromatosis’ were found in British red squirrels. Leprosy may also be found in nine-banded armadillos (Dasypus novemcinctus) where it can cause a zoonotic human infection. Certain leprosy-like diseases, caused by uncultivable species in cats, for example, may be related to M. leprae. The closest extant relatives of leprosy bacilli are probably members of the M. haemophilum taxon, emerging pathogens with genomic and lipid biomarker similarities

Two-Loop ϕ4\phi^4-Diagrams from String Theory

Using the {\em cutting and sewing} procedure we show how to get Feynman diagrams, up to two-loop order, of $\Phi^{4}$-theory with an internal SU(N) symmetry group, starting from tachyon amplitudes of the open bosonic string theory. In a properly defined field theory limit, we easily identify the corners of the string moduli space reproducing the correctly normalized field theory amplitudes expressed in the Schwinger parametrization.Comment: 28 pages, 12 figure

Catholic Healthcare Organizations and the Articulation of Their Identity

Contains fulltext : 69947.pdf (publisher's version ) (Open Access

Probing the non-thermal emission in the Perseus cluster with the JVLA

Large scale structure and cosmolog

Can forest management based on natural disturbances maintain ecological resilience?

Given the increasingly global stresses on forests, many ecologists argue that managers must maintain ecological resilience: the capacity of ecosystems to absorb disturbances without undergoing fundamental change. In this review we ask: Can the emerging paradigm of natural-disturbance-based management (NDBM) maintain ecological resilience in managed forests? Applying resilience theory requires careful articulation of the ecosystem state under consideration, the disturbances and stresses that affect the persistence of possible alternative states, and the spatial and temporal scales of management relevance. Implementing NDBM while maintaining resilience means recognizing that (i) biodiversity is important for long-term ecosystem persistence, (ii) natural disturbances play a critical role as a generator of structural and compositional heterogeneity at multiple scales, and (iii) traditional management tends to produce forests more homogeneous than those disturbed naturally and increases the likelihood of unexpected catastrophic change by constraining variation of key environmental processes. NDBM may maintain resilience if silvicultural strategies retain the structures and processes that perpetuate desired states while reducing those that enhance resilience of undesirable states. Such strategies require an understanding of harvesting impacts on slow ecosystem processes, such as seed-bank or nutrient dynamics, which in the long term can lead to ecological surprises by altering the forest's capacity to reorganize after disturbance