1,045 research outputs found

    Stability of Circular Orbits in General Relativity: A Phase Space Analysis

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    Phase space method provides a novel way for deducing qualitative features of nonlinear differential equations without actually solving them. The method is applied here for analyzing stability of circular orbits of test particles in various physically interesting environments. The approach is shown to work in a revealing way in Schwarzschild spacetime. All relevant conclusions about circular orbits in the Schwarzschild-de Sitter spacetime are shown to be remarkably encoded in a single parameter. The analysis in the rotating Kerr black hole readily exposes information as to how stability depends on the ratio of source rotation to particle angular momentum. As a wider application, it is exemplified how the analysis reveals useful information when applied to motion in a refractive medium, for instance, that of optical black holes.Comment: 20 pages. Accepted for publication in Int. J. theor. Phy

    A 12-week community-based physical activity and mindfulness intervention: health outcomes and markers of autonomic nervous system function (Sweet Hearts biokinetics pilot study)

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    The prevalence of non-communicable diseases (NCDs) has reached epidemic proportions in South Africa, coinciding with high levels of sedentary behaviour, urbanisation and stress. The nexus between stress, physical inactivity and non-communicable diseases may be regulated, in part, by changes in the autonomic nervous system (ANS). ANS function may be measured using a proxy of heart rate variability (HRV). Regular physical activity, controlled breathing and stress reduction have been shown to alter HRV. This paper presents preliminary data from a community-based biokinetics physical activity and mindfulness intervention (Sweet Hearts) on HRV. The study’s findings demonstrated favourable changes in measures of heart rate variability (HRV) – specifically in the low frequency (LF) spectrum that is associated with baroreflex function. The implications of these changes, in terms of health outcomes, along with efforts at addressing scalability and sustainability of community-based health promotion interventions may be important targets for future study

    Simu-dependent clearance of dying cells regulates macrophage function and inflammation resolution

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    Macrophages encounter and clear apoptotic cells during normal development and homeostasis, including at numerous sites of pathology. Clearance of apoptotic cells has been intensively studied, but the effects of macrophage–apoptotic cell interactions on macrophage behaviour are poorly understood. Using Drosophila embryos, we have exploited the ease of manipulating cell death and apoptotic cell clearance in this model to identify that the loss of the apoptotic cell clearance receptor Six-microns-under (Simu) leads to perturbation of macrophage migration and inflammatory responses via pathological levels of apoptotic cells. Removal of apoptosis ameliorates these phenotypes, while acute induction of apoptosis phenocopies these defects and reveals that phagocytosis of apoptotic cells is not necessary for their anti-inflammatory action. Furthermore, Simu is necessary for clearance of necrotic debris and retention of macrophages at wounds. Thus, Simu is a general detector of damaged self and represents a novel molecular player regulating macrophages during resolution of inflammation

    Structural differences of ethanol and DME jet flames in a hot diluted coflow

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    This study compares the flame structure of ethanol and dimethyl ether (DME) in a hot and diluted ox- idiser experimentally and computationally. Experiments were conducted on a Jet in Hot Coflow (JHC) burner, with the fuel jet issuing into a 1250-K coflow at three oxygen levels. Planar measurements using OH-LIF, CH 2 O-LIF, and Rayleigh scattering images reveal that the overall spatial distribution and evolution of OH, CH 2 O, and temperature were quite similar for the two fuels. For both the ethanol and the DME flames, a transitional flame structure occurred as the coflow oxygen level increased from 3% to 9%. This indicates that the flames shift away from the MILD combustion regime. Reaction flux analyses of ethanol and DME were performed with the OPPDIF code, and ethane (C 2 H 6 ) was also included in the analyses for comparison. These analyses reveal that the H 2 /O 2 pathways are very important for both ethanol and DME in the 3% O 2 cases. In contrast, the importance of fuel-specific reactions overtakes that of H 2 /O 2 reactions when fuels are burnt in the cold air or in the vitiated oxidant stream with 9% O 2 . Unsteady laminar flamelet analyses were also performed to investigate the ignition processes and help interpret experimental results. Flamelet equations were solved in time and mixture fraction field, which was pro- vided by non-reactive Large-Eddy Simulation (LES).Jingjing Ye, Paul R. Medwell, Konstantin Kleinheinz, Michael J. Evans, Bassam B. Dally, Heinz G. Pitsc

    Resonant laser tunnelling

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    We propose an experiment involving a gaussian laser tunneling through a twin barrier dielectric structure. Of particular interest are the conditions upon the incident angle for resonance to occur. We provide some numerical calculations for a particular choice of laser wave length and dielectric refractive index which confirm our expectations.Comment: 15 pages, 6 figure

    Brain Plasticity and Intellectual Ability Are Influenced by Shared Genes

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    Although the adult brain is considered to be fully developed and stable until senescence when its size steadily decreases, such stability seems at odds with continued human (intellectual) development throughout life. Moreover, although variation in human brain size is highly heritable, we do not know the extent to which genes contribute to individual differences in brain plasticity. In this longitudinal magnetic resonance imaging study in twins, we report considerable thinning of the frontal cortex and thickening of the medial temporal cortex with increasing age and find this change to be heritable and partly related to cognitive ability. Specifically, adults with higher intelligence show attenuated cortical thinning and more pronounced cortical thickening over time than do subjects with average or below average IQ. Genes influencing variability in both intelligence and brain plasticity partly drive these associations. Thus, not only does the brain continue to change well into adulthood, these changes are functionally relevant because they are related to intelligence. Copyright©2010 the authors

    Genetic contributions to human brain morphology and intelligence

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    Variation in gray matter (GM) and white matter (WM) volume of the adult human brain is primarily genetically determined. Moreover, total brain volume is positively correlated with general intelligence, and both share a common genetic origin. However, although genetic effects on morphology of specific GM areas in the brain have been studied, the heritability of focal WM is unknown. Similarly, it is unresolved whether there is a common genetic origin of focal GM and WM structures with intelligence. We explored the genetic influence on focal GM and WM densities in magnetic resonance brain images of 54 monozygotic and 58 dizygotic twin pairs and 34 of their siblings. For genetic analyses, we used structural equation modeling and voxel-based morphometry. To explore the common genetic origin of focal GM and WM areas with intelligence, we obtained cross-trait/cross-twin correlations in which the focal GM and WM densities of each twin are correlated with the psychometric intelligence quotient of his/her cotwin. Genes influenced individual differences in left and right superior occipitofrontal fascicle (heritability up to 0.79 and 0.77), corpus callosum (0.82, 0.80), optic radiation (0.69, 0.79), corticospinal tract (0.78, 0.79), medial frontal cortex (0.78, 0.83), superior frontal cortex (0.76, 0.80), superior temporal cortex (0.80, 0.77), left occipital cortex (0.85), left postcentral cortex (0.83), left posterior cingulate cortex (0.83), right parahippocampal cortex (0.69), and amygdala (0.80, 0.55). Intelligence shared a common genetic origin with superior occipitofrontal, callosal, and left optical radiation WM and frontal, occipital, and parahippocampal GM (phenotypic correlations up to 0.35). These findings point to a neural network that shares a common genetic origin with human intelligence

    The luminosities of protostars in the spitzer c2d and gould belt legacy clouds

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    Journal ArticlePublished version available online at the Astronomical Journal, Volume 145, Number 4, Article 94; doi: doi: 10.1088/0004-6256/145/4/94Motivated by the long-standing "luminosity problem" in low-mass star formation whereby protostars are underluminous compared to theoretical expectations, we identify 230 protostars in 18 molecular clouds observed by two Spitzer Space Telescope Legacy surveys of nearby star-forming regions. We compile complete spectral energy distributions, calculate L bol for each source, and study the protostellar luminosity distribution. This distribution extends over three orders of magnitude, from 0.01 L ȯ to 69 L ȯ, and has a mean and median of 4.3 L ȯ and 1.3 L ȯ, respectively. The distributions are very similar for Class 0 and Class I sources except for an excess of low luminosity (L bol ≲ 0.5 L) Class I sources compared to Class 0. 100 out of the 230 protostars (43%) lack any available data in the far-infrared and submillimeter (70 μm <λ < 850 μm) and have L bol underestimated by factors of 2.5 on average, and up to factors of 8-10 in extreme cases. Correcting these underestimates for each source individually once additional data becomes available will likely increase both the mean and median of the sample by 35%-40%. We discuss and compare our results to several recent theoretical studies of protostellar luminosities and show that our new results do not invalidate the conclusions of any of these studies. As these studies demonstrate that there is more than one plausible accretion scenario that can match observations, future attention is clearly needed. The better statistics provided by our increased data set should aid such future work. © 2013. The American Astronomical Society. All rights reserved..National Science FoundationNational Aeronautics and Space AdministrationJet Propulsion Laboratory, California Institute of Technolog

    First Measurement of Z/gamma* Production in Compton Scattering of Quasi-real Photons

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    We report the first observation of Z/gamma* production in Compton scattering of quasi-real photons. This is a subprocess of the reaction e+e- to e+e-Z/gamma*, where one of the final state electrons is undetected. Approximately 55 pb-1 of data collected in the year 1997 at an e+e- centre-of-mass energy of 183 GeV with the OPAL detector at LEP have been analysed. The Z/gamma* from Compton scattering has been detected in the hadronic decay channel. Within well defined kinematic bounds, we measure the product of cross-section and Z/gamma* branching ratio to hadrons to be (0.9+-0.3+-0.1) pb for events with a hadronic mass larger than 60 GeV, dominated by (e)eZ production. In the hadronic mass region between 5 GeV and 60 GeV, dominated by (e)egamma* production, this product is found to be (4.1+-1.6+-0.6) pb. Our results agree with the predictions of two Monte Carlo event generators, grc4f and PYTHIA.Comment: 18 pages, LaTeX, 5 eps figures included, submitted to Physics Letters
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