359 research outputs found
Nonperturbative late time asymptotics for heat kernel in gravity theory
Recently proposed nonlocal and nonperturbative late time behavior of the heat
kernel is generalized to curved spacetimes. Heat kernel trace asymptotics is
dominated by two terms one of which represents a trivial covariantization of
the flat-space result and another one is given by the Gibbons-Hawking integral
over asymptotically-flat infinity. Nonlocal terms of the effective action
generated by this asymptotics might underly long- distance modifications of the
Einstein theory motivated by the cosmological constant problem. New mechanisms
of the cosmological constant induced by infrared effects of matter and graviton
loops are briefly discussed.Comment: 22 pages, LaTeX, final version, to be published in Phys. Rev.
Translating Message Sequence Charts to other Process Languages Using Process Mining
Message Sequence Charts (MSCs) are often used by software analysts when discussing the behavior of a system with different stakeholders. Often such discussions lead to more complete behavioral models in the form of, e.g., Event-driven Process Chains (EPCs), Unified Modeling Language (UML), activity diagrams, Business Process Modeling Notation (BPMN) models, Petri nets, etc. Process mining on the other hand, deals with the problem of constructing complete behavioral models by analyzing event logs of information systems. In contrast to existing process mining techniques, where logs are assumed to only contain implicit information, the approach presented in this paper combines the explicit knowledge captured in individual MSCs and the techniques and tools available in the process mining domain. This combination allows us to discover high-quality process models. To constructively add to the existing work on process mining, our approach has been implemented in the process mining framework ProM (www.processmining.org)
On the Infrared Exponent for Gluon and Ghost Propagation in Landau Gauge QCD
In the covariant description of confinement, one expects the ghost
correlations to be infrared enhanced. Assuming ghost dominance, the long-range
behavior of gluon and ghost correlations in Landau gauge QCD is determined by
one exponent kappa. The gluon propagator is infrared finite (vanishing) for
kappa =1/2 (kappa > 1/2) which is still under debate. Here, we study critical
exponent and coupling for the infrared conformal behavior from the asymptotic
form of the solutions to the Dyson-Schwinger equations in an ultraviolet finite
expansion scheme. The value for kappa is directly related to the ghost-gluon
vertex. Assuming that it is regular in the infrared, one obtains kappa = 0.595.
This value maximizes the critical coupling alpha_c(kappa), yielding alpha_c^max
= (4 Pi/Nc) 0.709 approx. 2.97 for Nc=3. For larger kappa the vertex acquires
an infrared singularity in the gluon momentum, smaller ones imply infrared
singular ghost legs. Variations in alpha_c remain within 5% from kappa = 0.5 to
0.7. Above this range, alpha_c decreases more rapidly with alpha_c -> 0 as
kappa -> 1 which sets the upper bound on kappa.Comment: 22 Pages, 10 Figures, LaTeX2e, revtex4, some notes and references
added in response to communication
T-Analyst: a program for efficient analysis of protein conformational changes by torsion angles
T-Analyst is a user-friendly computer program for analyzing trajectories from molecular modeling. Instead of using Cartesian coordinates for protein conformational analysis, T-Analyst is based on internal bond-angle-torsion coordinates in which internal torsion angle movements, such as side-chain rotations, can be easily detected. The program computes entropy and automatically detects and corrects angle periodicity to produce accurate rotameric states of dihedrals. It also clusters multiple conformations and detects dihedral rotations that contribute hinge-like motions. Correlated motions between selected dihedrals can also be observed from the correlation map. T-Analyst focuses on showing changes in protein flexibility between different states and selecting representative protein conformations for molecular docking studies. The program is provided with instructions and full source code in Perl
Telomerase activity in B-cell non-Hodgkin lymphomas is regulated by hTERT transcription and correlated with telomere-binding protein expression but uncoupled from proliferation
Dietary species richness as a measure of food biodiversity and nutritional quality of diets
Biodiversity is key for human and environmental health. Available dietary and ecological indicators are not designed to assess the intricate relationship between food biodiversity and diet quality. We applied biodiversity indicators to dietary intake data from and assessed associations with diet quality of women and young children. Data from 24-hour diet recalls (55% in the wet season) of n = 6,226 participants (34% women) in rural areas from seven low- and middle-income countries were analyzed. Mean adequacies of vitamin A, vitamin C, folate, calcium, iron, and zinc and diet diversity score (DDS) were used to assess diet quality. Associations of biodiversity indicators with nutrient adequacy were quantified using multilevel models, receiver operating characteristic curves, and test sensitivity and specificity. A total of 234 different species were consumed, of which <30% were consumed in more than one country. Nine species were consumed in all countries and provided, on average, 61% of total energy intake and a significant contribution of micronutrients in the wet season. Compared with Simpsonâs index of diversity and functional diversity, species richness (SR) showed stronger associations and better diagnostic properties with micronutrient adequacy. For every additional species consumed, dietary nutrient adequacy increased by 0.03 (P < 0.001). Diets with higher nutrient adequacy were mostly obtained when both SR and DDS were maximal. Adding SR to the minimum cutoff for minimum diet diversity improved the ability to detect diets with higher micronutrient adequacy in women but not in children. Dietary SR is recommended as the most appropriate measure of food biodiversity in diets
Performance of the WeNMR CS-Rosetta3 web server in CASD-NMR
We present here the performance of the WeNMR CS-Rosetta3 web server in CASD-NMR, the critical assessment of automated structure determination by NMR. The CS-Rosetta server uses only chemical shifts for structure prediction, in combination, when available, with a post-scoring procedure based on unassigned NOE lists (Huang et al. in J Am Chem Soc 127:1665-1674, 2005b, doi: 10.1021/ja047109h). We compare the original submissions using a previous version of the server based on Rosetta version 2.6 with recalculated targets using the new R3FP fragment picker for fragment selection and implementing a new annotation of prediction reliability (van der Schot et al. in J Biomol NMR 57:27-35, 2013, doi: 10.1007/s10858-013-9762-6), both implemented in the CS-Rosetta3 WeNMR server. In this second round of CASD-NMR, the WeNMR CS-Rosetta server has demonstrated a much better performance than in the first round since only converged targets were submitted. Further, recalculation of all CASD-NMR targets using the new version of the server demonstrates that our new annotation of prediction quality is giving reliable results. Predictions annotated as weak are often found to provide useful models, but only for a fraction of the sequence, and should therefore only be used with caution
Young volcanism and related hydrothermal activity at 5°S on the slow-spreading southern Mid-Atlantic Ridge
The effect of volcanic activity on submarine hydrothermal systems has been well documented along fast- and intermediate-spreading centers but not from slow-spreading ridges. Indeed, volcanic eruptions are expected to be rare on slow-spreading axes. Here we report the presence of hydrothermal venting associated with extremely fresh lava flows at an elevated, apparently magmatically robust segment center on the slow-spreading southern Mid-Atlantic Ridge near 5°S. Three high-temperature vent fields have been recognized so far over a strike length of less than 2 km with two fields venting phase-separated, vapor-type fluids. Exit temperatures at one of the fields reach up to 407°C, at conditions of the critical point of seawater, the highest temperatures ever recorded from the seafloor. Fluid and vent field characteristics show a large variability between the vent fields, a variation that is not expected within such a limited area. We conclude from mineralogical investigations of hydrothermal precipitates that vent-fluid compositions have evolved recently from relatively oxidizing to more reducing conditions, a shift that could also be related to renewed magmatic activity in the area. Current high exit temperatures, reducing conditions, low silica contents, and high hydrogen contents in the fluids of two vent sites are consistent with a shallow magmatic source, probably related to a young volcanic eruption event nearby, in which basaltic magma is actively crystallizing. This is the first reported evidence for direct magmatic-hydrothermal interaction on a slow-spreading mid-ocean ridge
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