1,866 research outputs found
A qualitative perspective on multiple health behaviour change: views of smoking cessation advisors who promote physical activity
There are mixed views on whether smoking cessation advisors should focus only on quitting smoking or also promote simultaneous health behaviour changes (e.g. diet, physical activity), but no studies have qualitatively examined the views and vicarious experiences of such health professionals. Semi-structured interviews were conducted with 11 trained smoking cessation advisors who promote physical activity to their clients. The data were categorised into themes using thematic analysis supported by qualitative data analysis software. We report themes that were related to why advisors promote multiple health behaviour change and issues in timing. Physical activity could be promoted as a cessation aid and also as part of a holistic lifestyle change consistent with a non-smoker identity, thereby increasing feelings of control and addressing fear of weight gain. Multiple changes were promoted pre-quit, simultaneously and post-quit, and advisors asserted that it is important to focus on the needs and capabilities of individual clients when deciding how to time multiple changes. Also, suggesting that PA was a useful and easily performed cessation aid rather than a new behaviour (i.e. structured exercise that may seem irrelevant) may help some clients to avoid a sense of overload
Readiness to use physical activity as a smoking cessation aid: a multiple behaviour change application of the Transtheoretical Model among quitters attending Stop Smoking Clinics
Objective: Physical activity (PA) reduces cigarette cravings during smoking abstinence. However, little is known about quitters’ use of PA. This study aimed to: (1) determine the extent of quitters’ past and current use of PA as a cessation aid, while attempting to quit; (2) examine the relationship between use of PA and quitter characteristics and cognitions, within the Transtheoretical Model framework.
Methods: Self-report surveys were completed by 181 smokers attending Stop Smoking Services in England and Scotland.
Results: Twenty-two percent of quitters reported currently using PA to control their smoking, and 35% had used it during a previous quit attempt. Those in a more advanced stage of readiness for using PA as a cessation aid, held more positive beliefs regarding self-efficacy and outcome efficacy.
Conclusion: Quitters were more likely to use PA to help them quit when they had greater belief in their own ability to use PA and in the efficacy of PA to help them to quit, and were also meeting weekly PA targets for health.
Practice implications: Strategies by stop smoking advisors that aim to enhance client self-efficacy and outcome efficacy beliefs regarding PA as a cessation aid may help to increase the use of this behavioural strategy, since it seems that most quitters do not use PA
Expression of tumor necrosis factor by different tumor cell lines results either in tumor suppression or augmented metastasis
Tumor necrosis factor (TNF) produced by tumor cells after gene transfer can effectively suppress the growth of locally growing tumors. We wanted to test the effects of "local" TNF on the growth of a highly metastatic cell line. Therefore, a recombinant retrovirus allowing expression of the TNF gene by the beta-actin promotor has been constructed and used to infect the two tumor cell lines EB and ESB, which grow as solid tumor or metastasize, respectively. Expression of TNF by EB cells resulted in their rapid and dose-dependent rejection. In sharp contrast, mice injected with ESB cells producing similar amounts of TNF showed no signs of tumor suppression, but rather had reduced survival rates that correlated with enhanced hepatic metastases. The accelerated formation of liver metastases by ESB TNF cells could be reversed by an anti-TNF mAb. These results demonstrate the opposite effects TNF may have on tumor growth: suppression of a locally growing tumor and promotion of metastasis formation
Hybrid Newton-type method for a class of semismooth equations
In this paper, we present a hybrid method for the solution of a class of composite semismooth equations encountered frequently in applications. The method is obtained by combining a generalized finite-difference Newton method to an inexpensive direct search method. We prove that, under standard assumptions, the method is globally convergent with a local rate of convergence which is superlinear or quadratic. We report also several numerical results obtained applying the method to suitable reformulations of well-known nonlinear complementarity problem
Integrating the promotion of physical activity within a smoking cessation programme: Findings from collaborative action research in UK Stop Smoking Services
Background: Within the framework of collaborative action research, the aim was to explore the feasibility of
developing and embedding physical activity promotion as a smoking cessation aid within UK 6/7-week National
Health Service (NHS) Stop Smoking Services.
Methods: In Phase 1 three initial cycles of collaborative action research (observation, reflection, planning,
implementation and re-evaluation), in an urban Stop Smoking Service, led to the development of an integrated
intervention in which physical activity was promoted as a cessation aid, with the support of a theoretically based
self-help guide, and self monitoring using pedometers. In Phase 2 advisors underwent training and offered the
intervention, and changes in physical activity promoting behaviour and beliefs were monitored. Also, changes in
clients’ stage of readiness to use physical activity as a cessation aid, physical activity beliefs and behaviour and
physical activity levels were assessed, among those who attended the clinic at 4-week post-quit. Qualitative data
were collected, in the form of clinic observation, informal interviews with advisors and field notes.
Results: The integrated intervention emerged through cycles of collaboration as something quite different to
previous practice. Based on field notes, there were many positive elements associated with the integrated
intervention in Phase 2. Self-reported advisors’ physical activity promoting behaviour increased as a result of
training and adapting to the intervention. There was a significant advancement in clients’ stage of readiness to use physical activity as a smoking cessation aid.
Conclusions: Collaboration with advisors was key in ensuring that a feasible intervention was developed as an aid to smoking cessation. There is scope to further develop tailored support to increasing physical activity and
smoking cessation, mediated through changes in perceptions about the benefits of, and confidence to do physical activity
Variational study of the Holstein polaron
The paper deals with the ground and the first excited state of the polaron in
the one dimensional Holstein model. Various variational methods are used to
investigate both the weak coupling and strong coupling case, as well as the
crossover regime between them. Two of the methods, which are presented here for
the first time, introduce interesting elements to the understanding of the
nature of the polaron. Reliable numerical evidence is found that, in the strong
coupling regime, the ground and the first excited state of the self-trapped
polaron are well described within the adiabatic limit. The lattice vibration
modes associated with the self-trapped polarons are analyzed in detail, and the
frequency softening of the vibration mode at the central site of the small
polaron is estimated. It is shown that the first excited state of the system in
the strong coupling regime corresponds to the excitation of the soft phonon
mode within the polaron. In the crossover regime, the ground and the first
excited state of the system can be approximated by the anticrossing of the
self-trapped and the delocalized polaron state. In this way, the connection
between the behavior of the ground and the first excited state is qualitatively
explained.Comment: 11 pages, 4 figures, PRB 65, 14430
Accelerator system for the PRISM based muon to electron conversion experiment
The next generation of lepton flavor violation experiments need high
intensity and high quality muon beams. Production of such beams requires
sending a short, high intensity proton pulse to the pion production target,
capturing pions and collecting the resulting muons in the large acceptance
transport system. The substantial increase of beam quality can be obtained by
applying the RF phase rotation on the muon beam in the dedicated FFAG ring,
which was proposed for the PRISM project.This allows to reduce the momentum
spread of the beam and to purify from the unwanted components like pions or
secondary protons. A PRISM Task Force is addressing the accelerator and
detector issues that need to be solved in order to realize the PRISM
experiment. The parameters of the required proton beam, the principles of the
PRISM experiment and the baseline FFAG design are introduced. The spectrum of
alternative designs for the PRISM FFAG ring are shown. Progress on ring main
systems like injection and RF are presented. The current status of the study
and its future directions are discussed.Comment: Studies performed within the PRISM Task Force initiativ
Rural continental aerosol properties and processes observed during the Hohenpeissenberg Aerosol Characterization Experiment (HAZE2002)
International audienceDetailed investigations of the chemical and microphysical properties of rural continental aerosols were performed during the HAZE2002 experiment, which was conducted in May 2002 at the Meteorological Observatory Hohenpeissenberg (DWD) in Southern Germany. Online measurements included: Size-resolved chemical composition of submicron particles; total particle number concentrations and size distributions over the diameter range of 3 nm to 9 ?m; gas-phase concentration of monoterpenes, CO, O3, OH, and H2SO4. Filter sampling and offline analytical techniques were used to determine: Fine particle mass (PM2.5), organic, elemental and total carbon in PM2.5 (OC2.5, EC2.5, TC2.5), and selected organic compounds (dicarboxylic acids, polycyclic aromatic hydrocarbons, proteins). Overall, the non-refractory components of submicron particles detected by aerosol mass spectrometry (PM1, 6.6±5.4 ?g m?3, arithmetic mean and standard deviation) accounted for ~62% of PM2.5 determined by filter gravimetry (10.6±4.7 ?g m?3). The relative proportions of non-refractory submicron particle components were: (23±39)% ammonium nitrate, (27±23)% ammonium sulfate, and (50±40)% organics (OM1). OM1 was closely correlated with PM1 (r2=0.9) indicating a near-constant ratio of non-refractory organics and inorganics. The average ratio of OM1 to OC2.5 was 2.1±1.4, indicating a high proportion of heteroelements in the organic fraction of the sampled rural aerosol. This is consistent with the high ratio of oxygenated organic aerosol (OOA) over hydrocarbon-like organic aerosol (HOA) inferred from the AMS results (4:1), and also with the high abundance of proteins (~3%) indicating a high proportion of primary biological material (~30%) in PM2.5. This finding was confirmed by low abundance of PAHs (?3) and EC (?3) in PM2.5 and detection of several secondary organic aerosol compounds (dicarboxylic acids) and their precursors (monoterpenes). New particle formation was observed almost every day with particle number concentrations exceeding 104 cm?3 (nighttime background level 1000?2000 cm?3). Closer inspection of two major events indicated that the observed nucleation agrees with ternary H2SO4/H2O/NH3 nucleation and that condensation of both organic and inorganic species contributed to particle growth
Folded Supersymmetry and the LEP Paradox
We present a new class of models that stabilize the weak scale against
radiative corrections up to scales of order 5 TeV without large corrections to
precision electroweak observables. In these `folded supersymmetric' theories
the one loop quadratic divergences of the Standard Model Higgs field are
cancelled by opposite spin partners, but the gauge quantum numbers of these new
particles are in general different from those of the conventional
superpartners. This class of models is built around the correspondence that
exists in the large N limit between the correlation functions of supersymmetric
theories and those of their non-supersymmetric orbifold daughters. By
identifying the mechanism which underlies the cancellation of one loop
quadratic divergences in these theories, we are able to construct simple
extensions of the Standard Model which are radiatively stable at one loop.
Ultraviolet completions of these theories can be obtained by imposing suitable
boundary conditions on an appropriate supersymmetric higher dimensional theory
compactified down to four dimensions. We construct a specific model based on
these ideas which stabilizes the weak scale up to about 20 TeV and where the
states which cancel the top loop are scalars not charged under Standard Model
color. Its collider signatures are distinct from conventional supersymmetric
theories and include characteristic events with hard leptons and missing
energy.Comment: 18 pages, 5 figures, references correcte
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