Three new species of Neozygina Dietrich & Dmitriev (Hemiptera, Cicadellidae, Typhlocybinae) from Argentina, with a key to South American species

Three new species of Neozygina Dietrich & Dmitriev are described from Argentina, N. apicalis sp. nov., N. bifurcata sp. nov. and N. spinula sp. nov. Detailed morphological descriptions and illustrations of the new species are provided, and a key to South American species of the genus is given.Fil: Catalano, María Inés. Universidad Nacional del Noroeste de la Provincia de Buenos Aires. Departamento de Ciencias Básicas y Experimentales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Paradell, Susana. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. División Entomología; ArgentinaFil: Dietrich, Christopher H.. University of Illinois. Institute of Natural Resource Sustainabilit. Illinois Natural History Survey; Estados Unido

Lumped element kinetic inductance detectors maturity for space-borne instruments in the range between 80 and 180 GHz

This work intends to give the state-of-the-art of our knowledge of the performance of LEKIDs at millimetre wavelengths (from 80 to 180~GHz). We evaluate their optical sensitivity under typical background conditions and their interaction with ionising particles. Two LEKID arrays, originally designed for ground-based applications and composed of a few hundred pixels each, operate at a central frequency of 100, and 150~GHz ($\Delta \nu / \nu$ about 0.3). Their sensitivities have been characterised in the laboratory using a dedicated closed-circle 100~mK dilution cryostat and a sky simulator, allowing for the reproduction of realistic, space-like observation conditions. The impact of cosmic rays has been evaluated by exposing the LEKID arrays to alpha particles ($^{241}$Am) and X sources ($^{109}$Cd) with a readout sampling frequency similar to the ones used for Planck HFI (about 200~Hz), and also with a high resolution sampling level (up to 2~MHz) in order to better characterise and interpret the observed glitches. In parallel, we have developed an analytical model to rescale the results to what would be observed by such a LEKID array at the second Lagrangian point.Comment: 7 pages, 2 tables, 13 figure

Neutron Flux at the Gran Sasso Underground LaboratoryRevisited

The neutron flux induced by radioactivity at the Gran Sasso underground laboratory is revisited. We have performed calculations and Monte Carlo simulations; the results offer an independent check to the available experimental data reported by different authors, which vary rather widely. This study gives detailed information on the expected spectrum and on the variability of the neutron flux due to possible variations of the water content of the environment.Comment: 14 pages, 3 figures, systematic uncertainties adde

First report on the leafhopper genus Balera Young (Hemiptera, Cicadellidae, Typhlocybinae, Alebrini) from Argentina, and description of a new species

The genus Balera Young is reported for first time to Argentina and a new species is described, Balera floripara sp. n. Detailed morphological descriptions and illustrations of the new species and a key to males of known species are provided. Habralebra amoena is also recorded for the first time from Argentina.Facultad de Ciencias Naturales y Muse

Three new species of Neozygina Dietrich & Dmitriev (Hemiptera, Cicadellidae, Typhlocybinae) from Argentina, with a key to South American species

Three new species of Neozygina Dietrich & Dmitriev are described from Argentina, N. apicalis sp. nov., N. bifurcata sp. nov. and N. spinula sp. nov. Detailed morphological descriptions and illustrations of the new species are provided, and a key to South American species of the genus is given.Facultad de Ciencias Naturales y Muse

Niobium Silicon alloys for Kinetic Inductance Detectors

We are studying the properties of Niobium Silicon amorphous alloys as a candidate material for the fabrication of highly sensitive Kinetic Inductance Detectors (KID), optimized for very low optical loads. As in the case of other composite materials, the NbSi properties can be changed by varying the relative amounts of its components. Using a NbSi film with T_c around 1 K we have been able to obtain the first NbSi resonators, observe an optical response and acquire a spectrum in the band 50 to 300 GHz. The data taken show that this material has very high kinetic inductance and normal state surface resistivity. These properties are ideal for the development of KID. More measurements are planned to further characterize the NbSi alloy and fully investigate its potential.Comment: Accepted for publication on Journal of Low Temperature Physics. Proceedings of the LTD15 conference (Caltech 2013

Geoneutrinos in Borexino

This paper describes the Borexino detector and the high-radiopurity studies and tests that are integral part of the Borexino technology and development. The application of Borexino to the detection and studies of geoneutrinos is discussed.Comment: Conference: Neutrino Geophysics Honolulu, Hawaii December 14-16, 200

KCa3.1 inhibition switches the phenotype of glioma-infiltrating microglia/macrophages

Among the strategies adopted by glioma to successfully invade the brain parenchyma is turning the infiltrating microglia/macrophages (M/MΦ) into allies, by shifting them toward an anti-inflammatory, pro-tumor phenotype. Both glioma and infiltrating M/MΦ cells express the Ca(2+)-activated K(+) channel (KCa3.1), and the inhibition of KCa3.1 activity on glioma cells reduces tumor infiltration in the healthy brain parenchyma. We wondered whether KCa3.1 inhibition could prevent the acquisition of a pro-tumor phenotype by M/MΦ cells, thus contributing to reduce glioma development. With this aim, we studied microglia cultured in glioma-conditioned medium or treated with IL-4, as well as M/MΦ cells acutely isolated from glioma-bearing mice and from human glioma biopsies. Under these different conditions, M/MΦ were always polarized toward an anti-inflammatory state, and preventing KCa3.1 activation by 1-[(2-Chlorophenyl)diphenylmethyl]-1H-pyrazole (TRAM-34), we observed a switch toward a pro-inflammatory, antitumor phenotype. We identified FAK and PI3K/AKT as the molecular mechanisms involved in this phenotype switch, activated in sequence after KCa3.1. Anti-inflammatory M/MΦ have higher expression levels of KCa3.1 mRNA (kcnn4) that are reduced by KCa3.1 inhibition. In line with these findings, TRAM-34 treatment, in vivo, significantly reduced the size of tumors in glioma-bearing mice. Our data indicate that KCa3.1 channels are involved in the inhibitory effects exerted by the glioma microenvironment on infiltrating M/MΦ, suggesting a possible role as therapeutic targets in glioma