Temporal and spatial patterns in aerosol insecticide droplet distribution: Modifying application strategies to improve coverage and efficacy

With the phase-out of methyl bromide, treatment of food facilities with aerosol insecticides as part of management programs has increased. The physical layout of the structure, the distribution of equipment and other items within the space, and the application method and location may all cause spatial variation in how the insecticide is deposited, which can result in areas with insufficient or excessive amounts of insecticide applied. The impact of aerosol insecticide application position and dispersal method/formulation on the distribution of droplets was evaluated using a series of applications within the same flour mill room. The spatial pattern of droplet distribution and the effect of treatment on bioassay insects (Tribolium confusum Jacquelin DuVal) was evaluated. There was variation in aerosol concentration and droplet size distributions within room and application position had an impact on the spatial pattern of aerosol droplets. The further away and more obstructed by structural features a location was the lower the aerosol concentration, but concentration was also lower to the side and behind the release point. Evaluation of the temporal pattern in droplet deposition shows that most larger droplets settle out of the air relatively quickly, supporting that idea that shorter shutdown times are be possible. Efficacy was correlated with droplet concentration. The overall conclusion is that there can be considerable variation in distribution of aerosol insecticides and as a result considerable potential for improvement in the effectiveness of these applications.With the phase-out of methyl bromide, treatment of food facilities with aerosol insecticides as part of management programs has increased. The physical layout of the structure, the distribution of equipment and other items within the space, and the application method and location may all cause spatial variation in how the insecticide is deposited, which can result in areas with insufficient or excessive amounts of insecticide applied. The impact of aerosol insecticide application position and dispersal method/formulation on the distribution of droplets was evaluated using a series of applications within the same flour mill room. The spatial pattern of droplet distribution and the effect of treatment on bioassay insects (Tribolium confusum Jacquelin DuVal) was evaluated. There was variation in aerosol concentration and droplet size distributions within room and application position had an impact on the spatial pattern of aerosol droplets. The further away and more obstructed by structural features a location was the lower the aerosol concentration, but concentration was also lower to the side and behind the release point. Evaluation of the temporal pattern in droplet deposition shows that most larger droplets settle out of the air relatively quickly, supporting that idea that shorter shutdown times are be possible. Efficacy was correlated with droplet concentration. The overall conclusion is that there can be considerable variation in distribution of aerosol insecticides and as a result considerable potential for improvement in the effectiveness of these applications

Bayesian D-Optimal Choice Designs for Mixtures

__Abstract__ \n \nConsumer products and services can often be described as mixtures of ingredients. Examples are the mixture of ingredients in a cocktail and the mixture of different components of waiting time (e.g., in-vehicle and out-of-vehicle travel time) in a transportation setting. Choice experiments may help to determine how the respondents\' choice of a product or service is affected by the combination of ingredients. In such studies, individuals are confronted with sets of hypothetical products or services and they are asked to choose the most preferred product or service from each set. \n \nHowever, there are no studies on the optimal design of choice experiments involving mixtures. We propose a method for generating an optimal design for such choice experiments. To this end, we first introduce mixture models in the choice context and next present an algorithm to construct optimal experimental designs, assuming the multinomial logit model is used to analyze the choice data. To overcome the problem that the optimal designs depend on the unknown parameter values, we adopt a Bayesian D-optimal design approach. We also consider locally D-optimal designs and compare the performance of the resulting designs to those produced by a utility-neutral (UN) approach in which designs are based on the assumption that individuals are indifferent between all choice alternatives. We demonstrate that our designs are quite different and in general perform better than the UN designs

Hippocampal Sclerosis of Aging, a Prevalent and High-Morbidity Brain Disease

Hippocampal sclerosis of aging (HS-Aging) is a causative factor in a large proportion of elderly dementia cases. The current definition of HS-Aging rests on pathologic criteria: neuronal loss and gliosis in the hippocampal formation that is out of proportion to AD-type pathology. HS-Aging is also strongly associated with TDP-43 pathology. HS-Aging pathology appears to be most prevalent in the oldest-old: autopsy series indicate that 5-30 % of nonagenarians have HS-Aging pathology. Among prior studies, differences in study design have contributed to the study-to-study variability in reported disease prevalence. The presence of HS-Aging pathology correlates with significant cognitive impairment which is often misdiagnosed as AD clinically. The antemortem diagnosis is further confounded by other diseases linked to hippocampal atrophy including frontotemporal lobar degeneration and cerebrovascular pathologies. Recent advances characterizing the neurocognitive profile of HS-Aging patients have begun to provide clues that may help identify living individuals with HS-Aging pathology. Structural brain imaging studies of research subjects followed to autopsy reveal hippocampal atrophy that is substantially greater in people with eventual HS-Aging pathology, compared to those with AD pathology alone. Data are presented from individuals who were followed with neurocognitive and neuroradiologic measurements, followed by neuropathologic evaluation at the University of Kentucky. Finally, we discuss factors that are hypothesized to cause or modify the disease. We conclude that the published literature on HS-Aging provides strong evidence of an important and under-appreciated brain disease of aging. Unfortunately, there is no therapy or preventive strategy currently available

Stigmatising attitude of medical students towards a psychiatry label

This is an Open Access article distributed under the terms of the Creative Commons Attribution Licens

Performance of psychiatric hospital discharges in strict and tolerant environments

Community mental health professionals are greatly concerned with the type of social environment most conducive to helping patients remain outside psychiatric institutions and improving the quality of their lives in the community. This paper examines the tolerance of deviance characterizing significant others in the patient's environment as it relates to community tenure and selected measures of performance and quality of life of the older patient in the community. A possible role is suggested for differential tolerance of deviance in the lives of patients discharged from psychiatric hospitals. Although it would appear that patients may return to the hospital at a higher rate from low tolerance environments, it may be that for patients who remain in the community, the quality of life may be better in low tolerance environments in terms of social interaction and life satisfaction. The deviance model is of value in the continuing efforts to understand the role of the social environment in the community life of discharged patients .Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/44295/1/10597_2005_Article_BF01435737.pd

Humiliated fury is not universal: the co-occurrence of anger and shame in the United States and Japan

It has been widely believed that individuals transform high-intensity shame into anger because shame is unbearably painful. This phenomenon was first coined “humiliated fury,” and it has since received empirical support. The current research tests the novel hypothesis that shame-related anger is not universal, yet hinges on the cultural meanings of anger and shame. Two studies compared the occurrence of shamerelated anger in North American cultural contexts (where shame is devalued and anger is valued) to its occurrence in Japanese contexts (where shame is valued and anger is devalued). In a daily-diary study, participants rated anger and shame feelings during shame situations that occurred over one week. In a vignette study, participants rated anger and shame in response to standardised shame vignettes that were generated in previous research by either U.S. or Japanese respondents. Across the two studies, and in line with previous research on humiliated fury, shame predicted anger for U.S. participants. Yet, neither in the daily diary study nor for the Japanese-origin vignettes, did we find shame-related anger in Japanese participants. Only when presented with U.S.-origin vignettes, did Japanese respondents in the vignette study report shame-related anger. The findings suggest that shame-related anger is a culture-specific phenomenon

Exploring the Concepts of Recognition and Shame for Social Work

© 2016 GAPS. Recognition and shame are both concepts that potentially offer social workers a structure to build practice on; two states experienced by both social workers and service users. ‘Recognition’, within social, political and economic thought, has been established as a field in which inequality and exclusion can be analysed. Social work theorists have also made inroads into exploring its reach. ‘Shame’ in twentieth century and contemporary sociological and psychoanalytical accounts, is understood as a force in limiting human agency, well-being and capacity This paper briefly outlines some of the defining ideas in circulation in relation to recognition and shame, and then briefly considers how psychoanalytical and contemporary social structural analysis builds on this, making links to contemporary social work thinking throughout. The paper also specifically considers some of the uses of recognition and shame for thinking about social worker and service user ‘well-being’, and the connections, through both the relational and the socio-political, which inflect social work practice

Swimming in a Sea of Shame: Incorporating Emotions into Explanations of Institutional Reproduction and Change

We theorize the role in institutional processes of what we call the shame nexus, a set of shame-related constructs: felt shame, systemic shame, sense of shame, and episodic shaming. As a discrete emotion, felt shame signals to a person that a social bond is at risk and catalyzes a fundamental motivation to preserve valued bonds. We conceptualize systemic shame as a form of disciplinary power, animated by persons’ sense of shame, a mechanism of ongoing intersubjective surveillance and self-regulation. We theorize how the duo of the sense of shame and systemic shame drives the self-regulation that underpins persons’ conformity to institutional prescriptions and institutional reproduction. We conceptualize episodic shaming as a form of juridical power used by institutional guardians to elicit renewed conformity and reassert institutional prescriptions. We also explain how episodic shaming may have unintended effects, including institutional disruption and recreation, when it triggers sensemaking among targets and observers that can lead to the reassessment of the appropriateness of institutional prescriptions or the value of social bonds. We link the shame nexus to three broad categories of institutional work