Magma–host interactions during differentiation and emplacement of a shallow-level, zoned granitic pluton (Tarçouate pluton, Morocco): implications for magma emplacement

The Tarçouate pluton (Anti-Atlas, Morocco) is an inversely zoned laccolith emplaced 583 Ma ago into low-grade metasediments, with the following succession: leucocratic granites, biotite–granodiorites (±monzodiorites), hornblende–granodiorites (±monzodiorites) and monzodiorites syn-plutonic dykes. These rocks form two distinct, chemically coherent, units: (1) A main unit consists of layered (5

One-year prevalence and the impact of migraine and tension-type headache in Turkey: a nationwide home-based study in adults

Several studies have shown that the prevalence of migraine and tension-type headache (TTH) varied between different geographical regions. Therefore, there is a need of a nationwide prevalence study for headache in our country, located between Asia and Europe. This nationwide study was designed to estimate the 1-year prevalence of migraine and TTH and analyse the clinical features, the impact as well as the demographic and socio-economic characteristics of the participant households in Turkey. We planned to investigate 6,000 representative households in 21 cities of Turkey; and a total of 5,323 households (response rate of 89%) aged between 18 and 65 years were examined for headache by 33 trained physicians at home on the basis of the diagnostic criteria of the second edition of the International Classification of Headache Disorders (ICHD-II). The electronically registered questionnaire was based on the headache features, the associated symptoms, demographic and socio-economic situation and history. Of 5,323 participants (48.8% women; mean age 35.9 ± 12 years) 44.6% reported recurrent headaches during the last 1 year and 871 were diagnosed with migraine at a prevalence rate of 16.4% (8.5% in men and 24.6% in women), whereas only 270 were diagnosed with TTH at a prevalence rate of 5.1% (5.7% in men and 4.5% in women). The 1-year prevalence of probable migraine was 12.4% and probable TTH was 9.5% additionally. The rate of migraine with aura among migraineurs was 21.5%. The prevalence of migraine was highest among 35–40-year-old women while there were no differences in age groups among men and in TTH overall. More than 2/3 of migraineurs had ever consulted a physician whereas only 1/3 of patients with TTH had ever consulted a physician. For women, the migraine prevalence was higher among the ones with a lower income, while among men, it did not show any change by income. Migraine prevalence was lower in those with a lower educational status compared to those with a high educational status. Chronic daily headache was present in 3.3% and the prevalence of medication overuse headache was 2.1% in our population. There was an important impact of migraine with a monthly frequency of 5.9 ± 6, and an attack duration of 35.1 ± 72 h, but only 4.9% were on prophylactic treatment. The one-year prevalence of migraine estimated as 16.4% was similar or even higher than world-wide reported migraine prevalence figures and identical to a previous nation-wide study conducted in 1998, whereas the TTH prevalence was much lower using the same methodology with the ICHD-II criteria

Systems responses to progressive water stress in durum wheat

Durum wheat is susceptible to terminal drought which can greatly decrease grain yield. Breeding to improve crop yield is hampered by inadequate knowledge of how the physiological and metabolic changes caused by drought are related to gene expression. To gain better insight into mechanisms defining resistance to water stress we studied the physiological and transcriptome responses of three durum breeding lines varying for yield stability under drought. Parents of a mapping population (Lahn x Cham1) and a recombinant inbred line (RIL2219) showed lowered flag leaf relative water content, water potential and photosynthesis when subjected to controlled water stress time transient experiments over a six-day period. RIL2219 lost less water and showed constitutively higher stomatal conductance, photosynthesis, transpiration, abscisic acid content and enhanced osmotic adjustment at equivalent leaf water compared to parents, thus defining a physiological strategy for high yield stability under water stress. Parallel analysis of the flag leaf transcriptome under stress uncovered global trends of early changes in regulatory pathways, reconfiguration of primary and secondary metabolism and lowered expression of transcripts in photosynthesis in all three lines. Differences in the number of genes, magnitude and profile of their expression response were also established amongst the lines with a high number belonging to regulatory pathways. In addition, we documented a large number of genes showing constitutive differences in leaf transcript expression between the genotypes at control non-stress conditions. Principal Coordinates Analysis uncovered a high level of structure in the transcriptome response to water stress in each wheat line suggesting genome-wide co-ordination of transcription. Utilising a systems-based approach of analysing the integrated wheat's response to water stress, in terms of biological robustness theory, the findings suggest that each durum line transcriptome responded to water stress in a genome-specific manner which contributes to an overall different strategy of resistance to water stress

Identifying variation in resistance to the take-all fungus, Gaeumannomyces graminis var. tritici, between different ancestral and modern wheat species

Background: Ancestral wheat relatives are important sources of genetic diversity for the introduction of novel traits for the improvement of modern bread wheat. In this study the aim was to assess the susceptibility of 34 accessions of the diploid wheat Triticum monococcum (A genome) to Gaeumannomyces graminis var. tritici (Ggt), the causal agent of take-all disease. The second aim was to explore the susceptibility of tetraploid wheat (T. durum) and the B genome progenitor species Aegilops speltoides to Ggt. Results: Field trials, conducted over 5 years, identified seven T. monococcum accessions with a good level of resistance to take-all when exposed to natural inoculum under UK field conditions. All other accessions were highly susceptible or did not exhibit a consistent phenotype across years. DArT marker genotyping revealed that whole genome diversity was not closely related to resistance to take-all within T. monococcum, suggesting that multiple genetic sources of resistance may exist within the species. In contrast the tetraploid wheat cultivars and Ae. speltoides were all highly susceptible to the disease, including those with known elevated levels of benzoxazinoids. Conclusions: The diploid wheat species T. monococcum may provide a genetic source of resistance to take-all disease that could be utilised to improve the performance of T. aestivum in high disease risk situations. This represents an extremely valuable resource to achieve economic and sustainable genetic control of this root disease

Development of igneous layering during growth of pluton: The Tarçouate Laccolith (Morocco).

We discuss the significance of igneous layering with respect to pluton growth processes. The case study is the Tarçouate Laccolith (Morocco), whose core consists of modally layered hornblende granodiorites with high amount of monzodioritic enclaves, contrasting with peripheral, non-layered biotite granodiorites with low amount of enclaves. Rhythmic layering, with modal grading, cross-stratification and trough layering is associated with monzodioritic layers and wraps around mafic enclaves. Its steep dips ≥ 45° result from tilting that occurred above solidus conditions, as indicated by sub-vertical and synmagmatic granite, aplite and monzodiorite dykes cutting across the layering. The systematic association of igneous layering with mafic enclaves in calc-alkaline plutons suggests that layering originates from recurrent injection of mafic magma. Viscosity calculations suggest that the physicochemical properties of magma alone cannot account for the presence of layering in the central hornblende granodiorite and its coeval absence in the peripheral biotite granodiorite of the Tarçouate Laccolith. Intermittent pulses of hot mafic magma into crystallizing granodiorite likely produced thermal perturbations able to trigger local convection, formation of mafic enclaves and development of igneous layering through protracted crystallization

Titanium and barium incorporation into the phyllosilicate phases: The example of phlogopite-kinoshitalite solid solution

Extremely high abundances of BaO (up to 21.46 wt. % ) and TiO$_{2}$ (up to 13.85 wt. % ) are reported from brown phlogopite in calcite carbonatite inclusions from Jbel Saghro, Anti-Atlas Morocco. The substitution of Ba into the phlogopite structure can be explained by the scheme $^{[12]}$Ba + $^{[4]}$Al $\Leftrightarrow$ $^{[12]}$K + $^{[4]}$Si. At least 50 % of the K on the interlayer sites of phlogopites from Saghro is replaced by Ba. The incorporation of Ba into phlogopite allow the occurence of kinochitalite phases. Al compensates for tetrahedral Si deficiencies, and Ti is probably limited to octahedral substitution for Mg and Fe. A substitution scheme of the type Ba$^{2+}$ + 2Ti$^{4+}$ + 3Al$^{3+} \, \Leftrightarrow$ K$^{+}$ + 3(Mg, Fe)$^{2+}$ + 3Si$^{4+}$ is proposed

The Imilchil meteorite strewn field and Isli-Agoudal craters

New meteorite prospections at different places in the region of Imilchil showed that (1) besides the Ataxite of Tasraft all the other collected specimens belong to the same and only IIAB iron mother meteorite (2) the strewn field of the meteorite has a length of about 38 km into north-south direction (3) the small crater of Agoudal as well as the impact crater of Isli are situated on a parallel north-south axis, if not put together with the strewn field of the Imilchil meteorite (4) these two structures might be the result of the fall of the same and only mother meteorite of the IIAB type