A critical look at studies applying over-sampling on the TPEHGDB dataset

Preterm birth is the leading cause of death among young children and has a large prevalence globally. Machine learning models, based on features extracted from clinical sources such as electronic patient files, yield promising results. In this study, we review similar studies that constructed predictive models based on a publicly available dataset, called the Term-Preterm EHG Database (TPEHGDB), which contains electrohysterogram signals on top of clinical data. These studies often report near-perfect prediction results, by applying over-sampling as a means of data augmentation. We reconstruct these results to show that they can only be achieved when data augmentation is applied on the entire dataset prior to partitioning into training and testing set. This results in (i) samples that are highly correlated to data points from the test set are introduced and added to the training set, and (ii) artificial samples that are highly correlated to points from the training set being added to the test set. Many previously reported results therefore carry little meaning in terms of the actual effectiveness of the model in making predictions on unseen data in a real-world setting. After focusing on the danger of applying over-sampling strategies before data partitioning, we present a realistic baseline for the TPEHGDB dataset and show how the predictive performance and clinical use can be improved by incorporating features from electrohysterogram sensors and by applying over-sampling on the training set

Inhibition of the MEK1/ERK pathway reduces arachidonic acid release independently of cPLA(2) phosphorylation and translocation

BACKGROUND: The 85-kDa cytosolic phospholipase A(2) (cPLA(2)) mediates arachidonic acid (AA) release in MDCK cells. Although calcium and mitogen-activated protein kinases regulate cPLA(2), the correlation of cPLA(2) translocation and phosphorylation with MAPK activation and AA release is unclear. RESULTS: MEK1 inhibition by U0126 inhibited AA release in response to ATP and ionomycin. This directly correlated with inhibition of ERK activation but not with phosphorylation of cPLA(2) on Ser(505), which was only partially inhibited by ERK inhibition. Inhibition of AA release by U0126 was still observed when stoichiometric phosphorylation of cPLA(2) on Ser(505) was maintained by activating p38 with anisomycin. Translocation kinetics of wild-type cPLA(2) and cPLA(2) containing S505A or S727A mutations to Golgi were similar in response to ATP and ionomycin and were not affected by U0126. CONCLUSIONS: These results suggest that the ability of cPLA(2) to hydrolyze membrane phospholipid is reduced by inhibition of the MEK1/ERK pathway and that the reduction in activity is independent of cPLA(2) phosphorylation and translocation to membrane. The results also demonstrate that cPLA(2) mutated at the phosphorylation sites Ser(505) and Ser(727) translocated with similar kinetic as wild-type cPLA(2)

Advance Artificial Neural Network Classification Techniques Using EHG for Detecting Preterm Births

Worldwide the rate of preterm birth is increasing, which presents significant health, developmental and economic problems. Current methods for predicting preterm births at an early stage are inadequate. Yet, there has been increasing evidence that the analysis of uterine electrical signals, from the abdominal surface, could provide an independent and easy way to diagnose true labour and predict preterm delivery. This analysis provides a heavy focus on the use of advanced machine learning techniques and Electrohysterography (EHG) signal processing. Most EHG studies have focused on true labour detection, in the window of around seven days before labour. However, this paper focuses on using such EHG signals to detect preterm births. In achieving this, the study uses an open dataset containing 262 records for women who delivered at term and 38 who delivered prematurely. The synthetic minority oversampling technique is utilized to overcome the issue with imbalanced datasets to produce a dataset containing 262 term records and 262 preterm records. Six different artificial neural networks were used to detect term and preterm records. The results show that the best performing classifier was the LMNC with 96% sensitivity, 92% specificity, 95% AUC and 6% mean error

Evaluation of advanced artificial neural network classification and feature extraction techniques for detecting preterm births using ehg records

Globally, the rate of preterm births is increasing and this is resulting in significant health, development and economic problems. Current methods for the early detection of such births are inadequate. However, there has been some evidence to suggest that the analysis of uterine electrical signals, collected from the abdominal surface, could provide an independent and easier way to diagnose true labour and detect when preterm delivery is about to occur. Using advanced machine learning algorithms, in conjunction with electrohysterography signal processing, numerous studies have focused on detecting true labour several days prior to the event. In this paper however, the electrohysterography signals have been used to detect preterm births. This has been achieved using an open dataset that contains 262 records for women who delivered at term and 38 who delivered prematurely. Several new features from Electromyography studies have been utilized, as well as feature-ranking techniques to determine their discriminative capabilities in detecting term and preterm records. Seven artificial neural network algorithms are considered with the results showing that the Radial Basis Function Neural Network classifier performs the best, with 85% sensitivity, 80% specificity, 90% area under the curve and a 17% mean error rate. © 2014 Springer International Publishing Switzerland

Advanced Artificial Neural Network Classification for Detecting Preterm Births Using EHG Records

Globally, the rate of preterm births are increasing, thus resulting in significant health, development and economic problems. Current methods for the early detection of such births are inadequate. Nevertheless, there has been some evidence that the analysis of uterine electrical signals, collected from the abdominal surface, could provide an independent and easier way to diagnose true labour and detect when preterm delivery is about to occur. Using advanced machine learning algorithms, in conjunction with Electrohysterography signal processing, numerous studies have focused on detecting true labour several days prior to the event. However, in this paper, the Electrohysterography signals have been used to detect preterm births. This has been achieved using an open dataset, which contains 262 records for women who delivered at term and 38 who delivered prematurely. Several new features from Electromyography studies have been utilized, as well as feature-ranking techniques. Features are ranked to determine their discriminative capabilities in detecting term and preterm records. Seven different artificial neural networks were then used to identify these records. The results illustrate that the Radial Basis Function Neural Network classifier performed the best, with 85% sensitivity, 80% specificity, 90% area under the curve and a 17% mean error rate

Fluid Annotation: A Human-Machine Collaboration Interface for Full Image Annotation

We introduce Fluid Annotation, an intuitive human-machine collaboration interface for annotating the class label and outline of every object and background region in an image. Fluid annotation is based on three principles: (I) Strong Machine-Learning aid. We start from the output of a strong neural network model, which the annotator can edit by correcting the labels of existing regions, adding new regions to cover missing objects, and removing incorrect regions. The edit operations are also assisted by the model. (II) Full image annotation in a single pass. As opposed to performing a series of small annotation tasks in isolation, we propose a unified interface for full image annotation in a single pass. (III) Empower the annotator. We empower the annotator to choose what to annotate and in which order. This enables concentrating on what the machine does not already know, i.e. putting human effort only on the errors it made. This helps using the annotation budget effectively. Through extensive experiments on the COCO+Stuff dataset, we demonstrate that Fluid Annotation leads to accurate annotations very efficiently, taking three times less annotation time than the popular LabelMe interface.Comment: ACM MultiMedia 2018. Live demo is available at fluidann.appspot.co

Dynamic neural network architecture inspired by the immune algorithm to predict preterm deliveries in pregnant women

There has been some improvement in the treatment of preterm infants, which has helped to increase their chance of survival. However, the rate of premature births is still globally increasing. As a result, this group of infants is most at risk of developing severe medical conditions that can affect the respiratory, gastrointestinal, immune, central nervous, auditory and visual systems. There is a strong body of evidence emerging that suggests the analysis of uterine electrical signals, from the abdominal surface (Electrohysterography – EHG), could provide a viable way of diagnosing true labour and even predict preterm deliveries. This paper explores this idea further and presents a new dynamic self-organized network immune algorithm that classifies term and preterm records, using an open dataset containing 300 records (38 preterm and 262 term). Using the dataset, oversampling and cross validation techniques are evaluated against other similar studies. The proposed approach shows an improvement on existing studies with 89% sensitivity, 91% specificity, 90% positive predicted value, 90% negative predicted value, and an overall accuracy of 90%

A framework for automatic semantic video annotation

The rapidly increasing quantity of publicly available videos has driven research into developing automatic tools for indexing, rating, searching and retrieval. Textual semantic representations, such as tagging, labelling and annotation, are often important factors in the process of indexing any video, because of their user-friendly way of representing the semantics appropriate for search and retrieval. Ideally, this annotation should be inspired by the human cognitive way of perceiving and of describing videos. The difference between the low-level visual contents and the corresponding human perception is referred to as the ‘semantic gap’. Tackling this gap is even harder in the case of unconstrained videos, mainly due to the lack of any previous information about the analyzed video on the one hand, and the huge amount of generic knowledge required on the other. This paper introduces a framework for the Automatic Semantic Annotation of unconstrained videos. The proposed framework utilizes two non-domain-specific layers: low-level visual similarity matching, and an annotation analysis that employs commonsense knowledgebases. Commonsense ontology is created by incorporating multiple-structured semantic relationships. Experiments and black-box tests are carried out on standard video databases for action recognition and video information retrieval. White-box tests examine the performance of the individual intermediate layers of the framework, and the evaluation of the results and the statistical analysis show that integrating visual similarity matching with commonsense semantic relationships provides an effective approach to automated video annotation

A Mobile Health Monitoring Application for Obesity Management and Control Using the Internet-of-Things 1Mohamed

Obesity is one of the most serious and dangerous nutritional diseases around the world. Usually, people develop patterns of unhealthy eating that lead to increased body weight and accumulation of fat in the body. This mass happens due to an imbalance between the energy intake from food and energy consumed in the body. One of the primary treatments for this serious health risk include diets, physical activity, weight-loss training and adoption of health programs that promote healthy eating. As such, reliable mechanism to prevent and control the obesity levels is vital. It led many experts and researchers who are interested in the health sector to explore more solutions that help to combat the obesity phenomenon. This paper presents a mobile health application intended to increase the awareness levels of parents and children about the obesity risks and help them to sustain balanced and healthy eating lifestyle. The proposed mobile application is an educational tool for the evaluation of interventions to prevent obesity risk levels. The application is based on the Internet-of-Things approach, which allows tracking food intake, remote capturing and constant monitoring of children data with interactive feedback displayed on the mobile application