Study on Dosage Regimens of Asthma Medications in Pediatric Patients of Dr. M. Djamil Padang Hospital

A study on dosage regimens of asthma medications in pediatric patients hospitalized at the pediatrics ward DR. M. Djamil Padang hospital has been carried out. The purpose of this study was to determine and compare the suitability of dosage regimen given to pediatric patients in the pediatrics ward of Dr. M. Djamil Padang hospital with the literature. This study was conducted retrospectively with consecutive sampling technique. Samples were obtained from medical records during 2013. The results showed that the appropriate dosage administration of asthma medication for the prednisone, Combivent® and ambroxol were 100%, salbutamol 75%, and theophylline 0%. On the other hand, the entire medications showed 100% suitability concerning the route of administration. While for the interval of administration, the study showed that dexamethasone, prednisone, salbutamol, theophylline and ambroxol were 100% appropriate, but Combivent® was lower at 95.24%. The study concludes that the dose and interval of administration are not in accordance with the literature, while the route of administration is considered to be in accordance with the literature

Risk Factor of Rheumatoid Arthritis among Elderly in UPT Panti Werdha Mojopahit Mojokerto District Indonesia

Elderly is an event that will surely be experienced by all people who are blessed with longevity. Along with increasing age, physical and mental abilities are slowly decreased will cause many consequences so susceptible to a disease due to a decrease in the system of the usual complaints of the elderly due to the pain that is felt very disturbing rheumatic diseases. The purpose of this study was to identify risk factor of rheumatoid arthritis. This research used case-control design. The population in this study were all elderly in Mojopahit nursing home care. Divided into two groups, 21 cases and 21 control cases. Data collected by questionnaire to measure risk factors and to determine rheumatoid arthritis disease with observation sheet, data analyzed by logistic regression. The results obtained in the questionnaire of genetic risk factors showed an OR = 50 with CI 95% (5,486-484,783), meaning that elderly people with a family history of rheumatoid arthritis risk 50 times to experience rheumatoid arthritis. Risk factors for obesity show an OR value of 1.403 with 95% CI (0.129-15.291) which means obesity is not a risk factor for rheumatoid arthritis. Smoking risk factor showed the value of OR 1.177 with 95% CI (0,149-9,289) which means smoking history does not include risk factor for rheumatoid arthritis. Risk factors that affect rheumatoid arthritis were hereditary risk factors. The results of this study are expected to provide input to the nursing home care management in its efforts for the prevention and treatment of the disease

Peranan Perempuan dalam Perekonomian Keluarga dengan Memanfaatkan Sumberdaya Pertanian

This study aims to find out the reasons women decide to work as a farmer, knowing the understanding of women in the utilization of agricultural resources, and know how big the role of women in the intensification of the family economy. The method to determine the respondent used in this research is census method with numbering 100 persons. Analysis of the data used is descriptive analysis and qualitative analysis of revenue contribution. The results showed that the reasons women choose to work as farmers because of their desire to help their husbands in contributing family income which is driven by the load factors of family burden. Looking for experiences and shared responsibility are other reasons for women to work in agricultural activities. Their knowledge and understanding of agriculture, women are only know how to grow crops and produce. Stages how sustainable farming, care for the environment with organic farming systems is not yet implemented. This is caused by the lack of knowledge of owmen. Income contribution of women to family incomes is high, with a range of contribution 40% - 59% of total family income. This condition can be a reason for women to participate in decision-making within the household. So the presence of women within the family becomes more important and appreciated

Pengaruh Total Assets Turnover (TATO) dan Net Sales (NS) terhadap Return on Assets (ROA) PT. Telekomunikasi Indonesia Tbk

Tujuan penelitian ini adalah untuk menganalisis pengaruh Total Assets Turnover (TATO) dan Net Sales secara parsial dan simultan terhadap Return on Assets (ROA) pada PT. Telekomunikasi Indonesia Tbk Periode 2009-2018. Penelitian ini diolah dengan menggu¬nakan metode deskriptif dan pendekatan kuantitatif, serta menggunakan teknik analisis deskriptif dan analisis uji linier berganda. Secara simultan, Total Assets Turnover (TATO) dan Net Sales berpengaruh positif dan signifikan terhadap Return on Assets (ROA). Hal ini dibuktikan dengan perbandingan antara nilai Fhitung dan nilai Ftabel sebesar 5.619 > 4.74 dengan nilai signifikansi 0.035 < 0.05. Secara parsial, Total Assets turnover (TATO) berpengaruh positif dan signifikan terhadap Return on Assets (ROA) dan Net Sales berpengaruh negatif dan signifikan terhadap Return on Assets (ROA). Besaran pengaruh Total Assets Turnover (TATO) dan Net Sales terhadap Return on Assets (ROA) adalah 61.6%. Sedangkan, untuk 38.4% tingkat Return on Assets (ROA) dipengaruhi oleh variabel lain yang tidak diteliti dalam penelitian

scROSHI: robust supervised hierarchical identification of single cells

Identifying cell types based on expression profiles is a pillar of single cell analysis. Existing machine-learning methods identify predictive features from annotated training data, which are often not available in early-stage studies. This can lead to overfitting and inferior performance when applied to new data. To address these challenges we present scROSHI, which utilizes previously obtained cell type-specific gene lists and does not require training or the existence of annotated data. By respecting the hierarchical nature of cell type relationships and assigning cells consecutively to more specialized identities, excellent prediction performance is achieved. In a benchmark based on publicly available PBMC data sets, scROSHI outperforms competing methods when training data are limited or the diversity between experiments is large

Futures trading, spot price volatility and market efficiency: evidence from European real estate securities futures

In 2007 futures contracts were introduced based upon the listed real estate market in Europe. Following their launch they have received increasing attention from property investors, however, few studies have considered the impact their introduction has had. This study considers two key elements. Firstly, a traditional Generalized Autoregressive Conditional Heteroskedasticity (GARCH) model, the approach of Bessembinder & Seguin (1992) and the Gray’s (1996) Markov-switching-GARCH model are used to examine the impact of futures trading on the European real estate securities market. The results show that futures trading did not destabilize the underlying listed market. Importantly, the results also reveal that the introduction of a futures market has improved the speed and quality of information flowing to the spot market. Secondly, we assess the hedging effectiveness of the contracts using two alternative strategies (naïve and Ordinary Least Squares models). The empirical results also show that the contracts are effective hedging instruments, leading to a reduction in risk of 64 %

Thermomechanical couplings in shape memory alloy materials

In this work we address several theoretical and computational issues which are related to the thermomechanical modeling of shape memory alloy materials. More specifically, in this paper we revisit a non-isothermal version of the theory of large deformation generalized plasticity which is suitable for describing the multiple and complex mechanisms occurring in these materials during phase transformations. We also discuss the computational implementation of a generalized plasticity based constitutive model and we demonstrate the ability of the theory in simulating the basic patterns of the experimentally observed behavior by a set of representative numerical examples

An Analysis of Vascular Access Thrombosis Events From the Proactive IV irOn Therapy in hemodiALysis Patients Trial

INTRODUCTION: Treatment of anemia in dialysis patients has been associated with increased risk of vascular access thrombosis (VAT). Proactive IV irOn Therapy in hemodiALysis Patients (PIVOTAL) was a clinical trial of proactive compared with reactive i.v. iron therapy in patients requiring hemodialysis. We analyzed the trial data to determine whether randomized treatment arm, alongside other clinical and laboratory variables, independently associated with VAT. METHODS: In PIVOTAL, 2141 adult patients were randomized. The type of vascular access (arteriovenous fistula [AVF], arteriovenous graft [AVG], or central venous catheter [CVC]) was recorded at baseline and every month after randomization. The associations between clinical and laboratory data and first VAT were evaluated in a multivariate analysis. RESULTS: A total of 480 (22.4%) participants experienced VAT in a median of 2.1 years of follow-up. In multivariable analyses, treatment arm (proactive vs. reactive) was not an independent predictor of VAT (hazard ratio [HR] 1.13, P = 0.18). Diabetic kidney disease (HR 1.45, P < 0.001), AVG use (HR 2.29, P < 0.001), digoxin use (HR 2.48, P < 0.001), diuretic use (HR 1.25, P = 0.02), female sex (HR 1.33, P = 0.002), and previous/current smoker (HR 1.47, P = 0.004) were independently associated with a higher risk of VAT. Angiotensin receptor blocker (ARB) use (HR 0.66, P = 0.01) was independently associated with a lower risk of VAT. CONCLUSION: In PIVOTAL, VAT occurred in nearly 1 quarter of participants in a median of just >2 years. In this post hoc analysis, randomization to proactive i.v. iron treatment arms did not increase the risk of VAT