Measurement of income inequality in Mexico: methodology, assessment and empirical relationship with poverty and human development.

The intended contribution of this work is to systematically discuss a selection of methodological topics and some of the empirical and technical issues that have been driving the measurement of inequality in Mexico so far. This discussion has two strands: firstly, the general case, and second, the particular case of Mexico. The general case include some philosophical concerns, along with a review of the traditional inequality measurement, the most common operational decisions in empirical calculations, and the recent methodological contribution of development literature that is mostly centered around the capability approach of Sen (1985b). The philosophical part contrasted with other approaches and rejected the Marxist view of economic inequality, which is mostly viewed as an outcome of exploitation. The distributional judgments are compared with more ancient schools of thought in regards to justice. Another methodological issue is such that social inequality, approximated by income inequality, might be considered as an additional functioning that measures the degree of social cohesion in the country, this finding is an implication that comes from the definition of functionings within the capability approach; then, social inequality is a functioning that is different in nature from other measures of destitution, and it is also different from the destitution that is captured by absolute poverty measurement. Our general case includes a review of the most popular ways to measure inequality, such as normative and pragmatic inequality measures that are mentioned with their properties, with their rankings of the distributions provided by the use of stochastic dominance and quantile comparisons, and the construction of statistical models and some graphic representations of income economic inequality; the approach of inequality concerns included in the measurement of relative poverty is rejected for the sake of clarity. Then this general view would guide us to a better understanding of the Mexican literature for the consideration of income distribution. The measurement of destitution provided by governmental offices is necessary to discuss, because there might be some lack of coherence between the design of the measurement and the complex legal system in Mexico. We also consider a set of regulatory concerns that might not be unique to the Mexican law, but may be generalized for developing countries as a whole. Some of the methodological discussions that show how the Mexican research has been influenced by the international literature about human destitution will be good to clarify, looking at the value judgments that have been automatically accepted by the researchers. A sensitivity analysis was performed to the empirical calculation of inequality in Mexico, so the measurement showed to be different in regards to a variety of operational concerns: the recipient unit, the different data from income and consumption-expenditure surveys, various non-responses and underreported biases, the inclusion of a regional price index, among other things. In this work was also covered the reasons why it might be the case that destitution and poverty assessment was studied more deeply than inequality itself, so the possible ambiguity of inequality with poverty measurement is challenged in this work with a variety of theoretical remarks and empirical arguments. The final topic for the particular case of Mexico is to shed light in regards to the context of the capability approach and the use of equivalence scales, because these methodological approaches consider respectively directly and indirectly the assessment of distributional judgments. This discussion is followed by an empirical assessment of inequality measures that is related with a set of functionings and services, where a direct relationship of measures of inequality with other measures of destitution is made clear

The Complexity of Antibody-Dependent Enhancement of Dengue Virus Infection

Antibody-dependent enhancement (ADE) has been proposed as a mechanism to explain dengue hemorrhagic fever (DHF) in the course of a secondary dengue infection. Very recently, Dejnirattisai et al., 2010 [1], published an important article supporting the involvement of anti-prM antibodies in the ADE phenomenon. The complexity of ADE in the context of a secondary dengue infection is discussed here

Misprescription of antibiotics in primary care: a critical systematic review of its determinants

Background Antibiotic resistance is one of the principal public health problems worldwide. Currently, inappropriate use of antibiotics is regarded as the principal determinant of resistance, with most of these drugs being prescribed outside a hospital setting. This systematic review sought to identify the factors, attitudes and knowledge linked to misprescription of antibiotics. Methods A systematic review was conducted using the MEDLINE-PubMed and EMBASE databases. The selection criteria required that papers: (1) be published in English or Spanish; (2) designate their objective as that of addressing attitudes/ knowledge or other factors related with the prescribing of antibiotics; and (3) use quality and/or quantity indicators to define misprescription. The following were excluded: any paper that used qualitative methodology and any paper that included descriptive analysis only. Results A total of 46 papers that met the inclusion criteria were included in the review. They were very heterogeneous and displayed major methodological limitations. Doctors’ socio-demographic and personal factors did not appear to exert much influence. Complacency (fulfilling what professionals perceived as being patients’/parents’ expectations) and, to a lesser extent, fear (fear of possible complications in the patient) were the attitudes associated with misprescription of antibiotics. Conclusions Before designing interventions aimed at improving the prescription and use of antibiotics, studies are needed to identify precisely which factors influence prescribing

Prototype of a Plasma Generator for Electrosurgery

Plasma is one of the four fundamental states of matter and consists of highly ionized particles, it means, particles highly energized. Typically, plasma can be seen in neon lights or sudden electric discharges such as lightning or sparks. These ionized particles have sufficient energy (3 - 6 eV) to break organic molecular bonds within tissue. This property has been found useful for the application of plasma in surgeries as a cutting tool. Plasma has some advantages compared with other techniques for ablation (removal of tissue by cutting, vaporization, etc.), such as scalpel or electrocautery (cutting by vaporizating tissue applying an electric current), etcThis document presents the design and construction of a plasma generator for electrosurgical applications. The generator is comprised of four main parts: DC power supply, topology push-pull, controller unit and plasma probe. First results generating plasma by repetitively-pulsed electrical discharges in sodium chloride saline solution are reported

Elastic properties of graphene suspended on a polymer substrate by e-beam exposure

A method for fabricating multiple free-standing structures on the same sheet of graphene is demonstrated. Mechanically exfoliated mono- and bilayer graphene sheets were sandwiched between two layers of polymethyl-methacrylate. Suspended areas were defined by e-beam exposure allowing precise control over their shape and position. Mechanical characterization of suspended graphene sheets was performed by nanoindentation with an atomic force microscopy tip. The obtained built-in tensions of 12 nN are significantly lower than those in suspended graphene exfoliated on an SiO2 substrate, and therefore permit access to the intrinsic properties of this material system

Evaluación de la pertinencia de tesis doctorales como objetos de conocimiento: de literatura gris a medición del impacto

This article proposes a model to measure the relevance of doctoral theses as knowledge objects and their influence on researchers’ training. The quality conditions were evaluated in four dimensions: (1) internal consistency of the object of knowledge (thesis); (2) impact of the knowledge object and its application in the development of new scientific publications; (3) effect of the object of knowledge on the subject (student) as a researcher; and (4) collective consequences of the subject in research environments. To test the functionality of the model, data were collected from doctoral theses from two educational programs (liberal arts and sciences), by measuring the stability of the evaluated dimensions as a value chain, observing inconsistency in the results because of the consecutive weakening between the first and the last dimension.El artículo plantea un modelo para medir la pertinencia de las tesis doctorales como objetos de conocimiento y su influencia en la formación de investigadores. Se evaluaron las condiciones de calidad en cuatro dimensiones: (1) consistencia interna del objeto de conocimiento (tesis); (2) impacto del objeto de conocimiento y su aplicación en el desarrollo de nuevas publicaciones científicas; (3) efecto del objeto de conocimiento en el sujeto (tesista) como investigador; y (4) consecuencias colectivas del sujeto en entornos de investigación. Para probar la funcionalidad del modelo, se recolectaron datos de tesis doctorales provenientes de dos programas educativos (humanidades y ciencias químicas), a través de la medición de la estabilidad de las dimensiones evaluadas como cadena de valor, observándose inconsistencia en los resultados por la debilitación consecutiva entre la primera y la última dimensió

Immortalized human keratinocytes: A model system to study the efficacy of therapeutic drugs in response to the chemical warfare agent sulfur mustard (HD)

Cytokines have been established as biomarkers to detect exposure of cells to chemical warfare agents such as sulfur mustard (2,2'-dichlorodiethyl sulfide, HD). In this study cultured normal and SV40 immortalized human epidermal keratinocyte (NHEK/IHEK) cells were compared as potential model systems to measure the efficacy of therapeutic drugs against HD. Immortalized human epidermal keratinocytes resemble their primary cell counterparts but have the advantage of being carried through long-term culture. Immortalized cells also provide consistency and durability and are less costly than primary keratinocytes. Immunoassay studies were performed to examine the response of these two cell lines to HD. We found that both normal and immortalized NHEKs secreted the pro-inflammatory mediator interleukin-8 (IL-8) when exposed to HD. However, a major difference was observed between the NHEK cell line 6207 and IHEK cell line 425. IHEK cell line 425 produced higher levels of Interleuken-8 then those of its normal counterpart cell line 6207. This observation is significant since therapeutic drugs such as ibuprofen, which depress cytokine production, may not allow these biomarkers to be detected efficiently in experimental analysis of certain NHEK cell lines. The fact that Il-8 production higher in cell line 425 cell makes this in vitro model a potential screening tool to study the efficacy of drugs that suppress production of cytokine markers