46 research outputs found

    Electron-electron scattering effects on the Full Counting Statistics of Mesoscopic Conductors

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    In the hot electron regime, electron-electron scattering strongly modifies not only the shot noise but also the full counting statistics. We employ a method based on a stochastic path integral to calculate the counting statistics of two systems in which noise in the hot electron regime has been experimentally measured. We give an analytical expression for the counting statistics of a chaotic cavity and find that heating due to electron-electron scattering renders the distribution of transmitted charge symmetric in the shot noise limit. We also discuss the frequency dispersion of the third order correlation function and present numerical calculations for the statistics of diffusive wires in the hot electron regime

    ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries

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    This review summarizes the last decade of work by the ENIGMA (Enhancing NeuroImaging Genetics through Meta Analysis) Consortium, a global alliance of over 1400 scientists across 43 countries, studying the human brain in health and disease. Building on large-scale genetic studies that discovered the first robustly replicated genetic loci associated with brain metrics, ENIGMA has diversified into over 50 working groups (WGs), pooling worldwide data and expertise to answer fundamental questions in neuroscience, psychiatry, neurology, and genetics. Most ENIGMA WGs focus on specific psychiatric and neurological conditions, other WGs study normal variation due to sex and gender differences, or development and aging; still other WGs develop methodological pipelines and tools to facilitate harmonized analyses of "big data" (i.e., genetic and epigenetic data, multimodal MRI, and electroencephalography data). These international efforts have yielded the largest neuroimaging studies to date in schizophrenia, bipolar disorder, major depressive disorder, post-traumatic stress disorder, substance use disorders, obsessive-compulsive disorder, attention-deficit/hyperactivity disorder, autism spectrum disorders, epilepsy, and 22q11.2 deletion syndrome. More recent ENIGMA WGs have formed to study anxiety disorders, suicidal thoughts and behavior, sleep and insomnia, eating disorders, irritability, brain injury, antisocial personality and conduct disorder, and dissociative identity disorder. Here, we summarize the first decade of ENIGMA's activities and ongoing projects, and describe the successes and challenges encountered along the way. We highlight the advantages of collaborative large-scale coordinated data analyses for testing reproducibility and robustness of findings, offering the opportunity to identify brain systems involved in clinical syndromes across diverse samples and associated genetic, environmental, demographic, cognitive, and psychosocial factors

    Designing protected area networks that translate international conservation commitments into national action

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    Most countries have committed to protect 17% of their terrestrial area by 2020 through Aichi Target 11 of the Convention on Biological Diversity, with a focus on protecting areas of particular importance for biodiversity. This means national-scale spatial conservation prioritisations are needed to help meet this target and guide broader conservation and land-use policy development. However, to ensure these assessments are adopted by policy makers, they must also consider national priorities. This situation is exemplified by Guyana, a corner of Amazonia that couples high biodiversity with low economic development. In recent years activities that threaten biodiversity conservation have increased, and consequently, protected areas are evermore critical to achieving the Aichi targets. Here we undertake a cost-effective approach to protected area planning in Guyana that accounts for in-country conditions. To do this we conducted a stakeholder-led spatial conservation prioritisation based on meeting targets for 17 vegetation types and 329 vertebrate species, while minimising opportunity costs for forestry, mining, agriculture and urbanisation. Our analysis identifies 3 millio

    A bibliometric analysis of highly cited and high impact occupational therapy publications by American authors

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    [[abstract]]A bibliometric analysis was completed of peer-reviewed literature from 1991–2015, written by American occupational therapists, to examine US high impact scholarship with “occupational therapy” and “occupational therapist(s)” used as keywords to search journal articles’publication title, abstract, author details, and keywords. Results included 1,889 journal articles from 1991–2015 published by American occupational therapists as first or corresponding author. Sixty-nine articles attained a TotalCitation2015 50 and 151 attained a Citation2015 5 indicating that they were the most highly cited literature produced in this period. Although the majority (58%) of this literature was published in occupational therapy-specific journals, 41% was published in interdisciplinary journals. Results illustrate that the volume of highly cited American occupational therapy peer-reviewed literature has grown over the last two decades. There is need for the profession to strategize methods to enhance the publication metrics of occupational therapy-specific journals to reduce the loss of high quality publications to external periodicals

    Corrosion of deformed boiler steel in flushing solutions

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