Measuring and Modeling Behavioral Decision Dynamics in Collective Evacuation

Identifying and quantifying factors influencing human decision making remains an outstanding challenge, impacting the performance and predictability of social and technological systems. In many cases, system failures are traced to human factors including congestion, overload, miscommunication, and delays. Here we report results of a behavioral network science experiment, targeting decision making in a natural disaster. In each scenario, individuals are faced with a forced "go" versus "no go" evacuation decision, based on information available on competing broadcast and peer-to-peer sources. In this controlled setting, all actions and observations are recorded prior to the decision, enabling development of a quantitative decision making model that accounts for the disaster likelihood, severity, and temporal urgency, as well as competition between networked individuals for limited emergency resources. Individual differences in behavior within this social setting are correlated with individual differences in inherent risk attitudes, as measured by standard psychological assessments. Identification of robust methods for quantifying human decisions in the face of risk has implications for policy in disasters and other threat scenarios.Comment: Approved for public release; distribution is unlimite

Macrophage-specific responses to human -and animal- adapted tubercle bacilli reveal pathogen and host factors driving multinucleated cell formation

The Mycobacterium tuberculosis complex (MTBC) is a group of related pathogens that cause tuberculosis (TB) in mammals. MTBC species are distinguished by their ability to sustain in distinct host populations. While Mycobacterium bovis (Mbv) sustains transmission cycles in cattle and wild animals and causes zoonotic TB, M. tuberculosis (Mtb) affects human populations and seldom causes disease in cattle. The host and pathogen determinants underlying host tropism between MTBC species are still unknown. Macrophages are the main host cell that encounters mycobacteria upon initial infection, and we hypothesised that early interactions between the macrophage and mycobacteria influence species-specific disease outcome. To identify factors that contribute to host tropism, we analysed blood-derived primary human and bovine macrophages (hMϕ or bMϕ, respectively) infected with Mbv and Mtb. We show that Mbv and Mtb reside in different cellular compartments and differentially replicate in hMϕ whereas both Mbv and Mtb efficiently replicate in bMϕ. Specifically, we show that out of the four infection combinations, only the infection of bMϕ with Mbv promoted the formation of multinucleated giant cells (MNGCs), a hallmark of tuberculous granulomas. Mechanistically, we demonstrate that both MPB70 from Mbv and extracellular vesicles released by Mbv-infected bMϕ promote macrophage multinucleation. Importantly, we extended our in vitro studies to show that granulomas from Mbv-infected but not Mtb-infected cattle contained higher numbers of MNGCs. Our findings implicate MNGC formation in the contrasting pathology between Mtb and Mbv for the bovine host and identify MPB70 from Mbv and extracellular vesicles from bMϕ as mediators of this process

La vid silvestre en México. Actualidades y potencial

En ocho capítulos se aborda el estado del arte de la vid silvestre en MéxicoEl estudio de las especies vegetales nativas de México representa un reto que cada día más investigadores mexicanos asumen. Durante muchos años, el apoyo a la investigación pública ha sido mínimo; desde el punto de vista agronómico es insuficiente para avanzar a la velocidad que requiere nuestro país para afrontar problemas de producción y distribución de alimentos. Por esa razón, entre otras, me es grato presentar esta obra que compila parte de los trabajos de la Red de Vid Silvestre patrocinada por el Sistema Nacional de Recursos Fitogenéticos (sinarefi) dependiente de la sagarpa; trabajos apuntalados por investigadores que sin pertenecer a la red han colaborado en el estudio de las plantas del género Vitis. En este libro se muestra el potencial del país para aprovechar el recurso vid, empleado desde antes de la conquista española por nativos mexicanos que conocían sus bondades. Es necesario continuar el avance en el conocimiento de este recurso, por ello el presente libro pretende invitar a toda persona interesada en contribuir con el rescate y conservación de las vides mexicanas. Los autores y editores, así como las instituciones en donde laboramos y aquellas que patrocinan estas investigaciones, esperamos se cumpla este objetivo y que el lector, alumno, profesor, investigador, público en general, disfrute esta lectura y, sobre todo, se interese en el recurso VitisSEP, SINAREFI, UAEME

Planeación, gobernanza y sustentabilidad Retos y desafíos desde el enfoque territorial

Frente a la compleja realidad actual, resulta ineludible el desarrollo de la investigación científica de los fenómenos y procesos urbanos, territoriales y ambientales, que contribuya a su comprensión y la construcción de alternativas de solución a los retos y desafíos vigentes. En este contexto, el abordaje de las ciudades y regiones metropolitanas, el ordenamiento del territorio y la ocupación del espacio, así como la relación sociedad-naturaleza y la complejidad ambiental, precisa la generación de metodologías y procesos de investigación multi e inter disciplinarios que contribuyan a la comprensión de los procesos socioterritoriales, el mejoramiento de las condiciones de vida y la conservación ambiental.Programa de Fortalecimiento de la Calidad Educativa PFCE-2016 proyecto K0313101

Improving sector hash carving with rule-based and entropy-based non-probative block filters

Digital forensic investigators have traditionally used file hashes to identify known content on searched media. Recently, sector hashing has been proposed as an alternative identification method, in which files are broken up into blocks, which are then compared to sectors on searched media. Since sectors are read sequentially without accessing the file system, sector hashing can be parallelized easily and is faster than traditional methods. In addition, sector hashing can identify partial files, and does not require an exact file match. In some cases, the presence of even a single block is sufficient to demonstrate with high probability that a file resides on a drive. However, non-probative blocks, common across many files, generate false positive matches; a problem that must be addressed before sector hashing can be adopted. We conduct 7 experiments in two phases to filter non-probative blocks. Our first phase uses rule-based and entropy-based non-probative block filters to improve matching against all file types. In the second phase, we restrict the problem to JPEG files. We find that for general hash-based carving, a rule-based approach outperforms a simple entropy threshold. When searching for JPEGs, we find that an entropy threshold of 10.9 gives a precision of 80% and an accuracy of 99%.http://archive.org/details/improvingsectorh1094545194Civilian, Department of the NavyApproved for public release; distribution is unlimited

Quantitative Effect of Different Transition and Post-transition Metals in the Growth of <i>Rhodotorula mucilaginosa</i> strain UANL-001L and the Production of Exopolysaccharides.

<p>A) Dry biomass of <i>Rhodotorula mucilaginosa</i> strain UANL-001L (g) and <b>B)</b> Percentage Increase, compared to the control, in production of EPS, measured after growth in the presence of the different transition and post-transition metals (Cd(II), Pb(II), Zn(II), Ni(II), Cu(II) and Cr(VI)).</p

MICs of <i>Rhodotorula mucilaginosa</i> strain UANL-001L to Different Transition and Post-Transition Metals.

<p>MICs of <i>Rhodotorula mucilaginosa</i> strain UANL-001L to Different Transition and Post-Transition Metals.</p