Análisis de las descompensaciones glucémicas en los servicios de urgencias hospitalarios

Las descompensaciones glucémicas son una entidad muy prevalente entre los pacientes que acuden a un Servicio de Urgencias Hospitalario (SUH). OBJETIVOS: Conocer la incidencia y prevalencia de las descompensaciones de la glucemia en el SUH. Describir el perfil de los pacientes atendidos. Estudiar los factores de riesgo asociados y valorar la asociación de los mismos con el ingreso.OtroGrado en Medicin

Energy and Macronutrients Intake in Indoor Sport Team Athletes: Systematic Review

Indoor team sports are characterized by matches that are shorter in duration and with frequent substitution (high-intensity intermittent). The main goal of teams is to best cover athletes’ physiological demands, while meeting their dietary intake needs is critical. The aim of this study is to conduct a systematic review of the dietary intake of indoor team sports athletes and to analyze whether they comply with nutritional recommendations. A search of PubMed-MEDLINE, Web of Science, and Scopus databases from 2008 to July 2022 was conducted and 2727 documents were identified. The studies focused on adult professional or semi-professional volleyball, basketball, handball, or futsal athletes. Two independent researchers screened and extracted the data, with 20 documents included after they met the inclusion criteria. Most of the athletes, both men and women, did not meet the official recommendations based on under-consumption (energy and carbohydrates) or over-consumption (fats). In relation to protein, 28.6% of studies met the recommendations, with 50% of those who did not meet it being due to under-consumption. Although there are references on athletes’ dietary intakes, there are no references considering sexes or types of sport. More adapted recommendations are needed in order to more precisely evaluate athletes’ intake to know if they meet their real nutritional requirements

Sensitive glyphosate electrochemiluminescence immunosensor based on electrografted carbon nanodots

A novel electrochemiluminescence (ECL) immunosensor based on electrografted carbon nanodots (CND) is developed for the sensitive determination of glyphosate in soy milk and tea. Nitrogen rich CND were synthesized by microwave radiations using mild conditions and following the principles of green chemistry. L-Arginine and 3,3′-diamino-N-methyldipropylamine were selected as precursors. CND were exhaustively characterized as well as the resulting nanostructured electrodes after CND electrografting. The high stability of CND nanostructured electrode together with the high electrical conductivity and the improvement of the electrochemiluminescent properties from the luminophore [Ru(bpy)3]2+ makes it an excellent electrochemiluminescence detection platform for biosensing assays. The application to biosensors was assessed by combination with an immunoassay based on magnetic nanoparticles, in which anti-glyphosate-IgG coupled magnetic particles (MP-Ab) was used as recognition element of the analyte, glyphosate. The developed ECL immunosensor was successfully applied for the detection of glyphosate in a wide linear range from 28.9 to 200 pg/mL, a sensitivity of 3.38 × 10−3 mL/pg and a detection limit of 8.66 pg/mL. The immunosensor response is stable and reproducible and it has been applied to the determination of glyphosate in tea and soy milk, with results that agree with those provided by an ELISA kit involving the same immunoreagentsThis work has been supported by the Spanish Ministerio de Ciencia, Innovación y Universidades (CTQ2017-84309-C2-1-R; RED2018-102412-T) and Comunidad Autónoma de Madrid (P2018/NMT-4349 TRANSNANOAVANSENS Program and 2017-T1/BIO-5435 Atracción de Talento Project

La "activación" en las malfornaciones arteriovenosas congénitas.

Se presenta la experiencia en el diagnóstico y tratamiento de las malformaciones Arteriovenosas congénitas, comentando las diversas clasificaciones y analizando los tipos anatomo-histologicos de las lesiones, sus posibles factores etiológicos y sus síntomas. Asimismo se describen 49 casos que cambian su aspecto clínico tras sufrir un proceso de “Activación” que determina a su vez la modificación del tratamiento hacia medidas terapéuticas mas agresivas. Se describen los cambios clínicos locales, regionales y generales que condicionan la indicación quirúrgica o hemodinámica y los tratamientos médicos mas utilizados, incluyendo los fármacos de elección, la radioterapia, el laser o la esclerosis química, para finalizar comentando las opciones hemodinámicas (Embolizaciones) y las técnicas quirúrgicas radicales, que precisan muchas veces de intervenciones complementarias plásticas u ortopédicas para corregir las secuelas de la extirpaciones. Se concluye afirmando que la mejor opción es la embolización seguida de la resección amplia y radical cuando ello es posible.We present the experience in the diagnosis and treatment of congenital arteriovenous malformations, discussing the different classifications and analyzing the anatomic-histological types of responsible lesions, their possible etiological factors and symptoms. There are 49 cases that change their clinical appearance after undergoing an “Activation” process that forces the modification of the treatment towards more aggressive therapeutic measures. Local, regional, and general clinical changes, determining the surgical or hemodynamic indication, are described. The most widely used medical treatments, including drugs of choice, radiotherapy, laser or chemical sclerosis, are commented on. Finally, the hemodynamic options (Embolizations) and the radical surgical techniques (often requiring complementary plastic or orthopedic interventions) are discussed.We think that the best option is embolization followed by extensive and radical resection when this is possible

Veinticinco años del movimiento cannábico español

En España se ha creado una nueva cultura de consumo, comercio y representación. Esta cultura sigue transformándose y extendiéndose. La cultura del cannabis es una cultura de consumo de masas basada en un conjunto de significados compartidos sobre un aspecto central de las sociedades modernas como es el consumo para el ocio. Al mismo tiempo, genera identificaciones simbólicas entre colectivos que comparten una misma visión de esta realidad, un mismo interés y unas semejantes posiciones sociales.Spain has created a new culture of consumption, trade and representation. This culture continues to change and expand. Cannabis culture is a culture of mass consumption based on a set of shared meanings on a central aspect of modern societies as consumption for leisure. While it is generating symbolic identifications between groups that share a vision of this reality, the same interest and similar social positions

Programa de inclusión y terminalidad de la educación secundaria para jóvenes de 14 a 17 años (PIT) Córdoba (Argentina)

La principal línea de trabajo de esta investigación se centra en el estudio y análisis de una propuesta de política educativa del Gobierno de la Provincia de Córdoba,Argentina, que apunta a que los jóvenes de 14 a 17 años que permanecen fuera de la escuela se incluyan para completar la educación secundaria obligatoria y obtengan formación para el mundo del trabajo. El estudio del "Programa de Inclusión/Terminalidad de la Educación Secundaria y Formación laboral para Jóvenes de 14 a 17" en la ciudad de Córdoba y su área urbana posibilita indagar sobre la implementación de lineamientos de política pública en clave local.http://www.unicef.org/argentina/spanish/educacion_PIT_DIC_OKweb.pdfFil: Vanella, Liliana. Universidad Nacional de Córdoba. Facultad de Filosofía y Humanidades. Escuela de Ciencias de la Educación; Argentina.Fil: Maldonado, Mónica. Universidad Nacional de Córdoba. Facultad de Filosofía y Humanidades. Escuela de Ciencias de la Educación; Argentina.Fil: Abate Daga, Miriam. Universidad Nacional de Córdoba. Facultad de Filosofía y Humanidades. Departamento de Antropología; Argentina.Fil: Falconi, Octavio. Universidad Nacional de Córdoba. Facultad de Filosofía y Humanidades. Escuela de Ciencias de la Educación; Argentina.Fil: Gutiérrez, Gonzalo. Universidad Nacional de Córdoba. Facultad de Filosofía y Humanidades. Escuela de Filosofía; Argentina.Fil: Martínez, María Cecilia. Universidad Nacional de Córdoba. Facultad de Psicología; Argentina.Fil: Uanini, Mónica. Universidad Nacional de Córdoba. Facultad de Filosofía y Humanidades. Escuela de Ciencias de la Educación; Argentina.Educación General (incluye capacitación, pedagogía y didáctica

Evaluación del polimorfismo -592 C/A en el gen que codifica por interlucina 10 (IL-10) en pacientes con diagnóstico de sepsis bacteriana

PublishedLas altas tasas de mortalidad que se presentan alrededor de la sepsis ha hecho necesario buscar nuevos marcadores para abordar al paciente más oportunamente. El objetivo de este trabajo de grado fue establecer la asociación del polimorfismo -592C/A del gen IL-10 y el desarrollo de sepsis bacteriana y choque séptico en pacientes que se encuentran en la Unidad de cuidados Intensivos (UCI) de la Clínica Versalles de la ciudad de Cali durante el año 2018

Optical fibre spectroscopy sensor for the quantitative determination of industrial textile dyes

In this paper, an extrinsic optical fibre sensor (OFS) for the quantitative determination of dyes used in the textile industry is presented. The system proposed is based on absorption spectroscopy and multivariate calibration methods to infer the concentration of different textile dyes. The performance of the sensor has been successfully assessed using calibrated dyes, with a very good correlation between the multivariate calibration models and the predicted values. The sensor system here demonstrated could be used to predict the colour of dye mixtures during the dyebath and, therefore, reduce the manufacturing costs

Psychosis and Smoking Cessation: Difficulties in Quitting Associated with Sex and Substance Abuse

No prospective studies of first psychotic episodes have explored sex differences in smoking cessation. The aim of this study was to determine the influence of sex and substance abuse on smoking cessation during an 8-year follow-up of patients after a first psychotic episode. Logistic regression modeling was used to identify factors associated with smoking cessation by sex. To examine for sex variable interactions, the following two methods were used: 1) for other clinical variables, mixed analyses were calculated; and 2) for use of other substances, logistic regression models were performed only in the substance users. At baseline, 79% of men and 84% of women were current smokers. Lower smoking cessation after 8 years was associated with female sex (odds ratio, OR = 0.30; 95% confidence intervals, CIs = 0.12–0.75) and treatment with typical antipsychotics (OR = 0.30, CIs = 0.10–0.93). In a logistic regression model of alcohol users, those who used alcohol continuously were less likely to stop smoking (adjusted OR = 0.22, CI = 0.05–1.0). Among patients who continued using cannabis, female sex was associated with significant lower smoking cessation (adjusted OR = 0.03, CI = 0.001–0.77). Sex may act as a moderator in smoking cessation after a first psychotic episode. Smoking cessation interventions in these patients should consider sex differences and comorbidity with alcohol and cannabis use

Azure A embedded in carbon dots as NADH electrocatalyst: Development of a glutamate electrochemical biosensor

Carbon nanodots modified with azure A (AA-CDs) have been synthesized and applied as redox mediator of bioelectrocatalytic reactions. A deep characterization of AA-CDs nanomaterial has been carried out, proving the covalent attachment of azure A molecules into the carbon dots nanostructure. Disposable screen-printed carbon electrodes (SPCE) have been modified with AA-CDs, through the action of chitosan polymer (Chit-AA-CDs/SPCE). The Chit-AA-CDs/SPCE electrocatalytic activity towards the oxidation of NADH has been proved, obtaining excellent results regarding the low oxidation potential achieved (−0.15 V vs. Ag) and low detection and quantification limits (LOD and LOQ) for NADH, 16 and 53 µM, respectively. The developed electrochemical platform has been applied for the construction of a glutamate biosensor by immobilizing L-glutamic dehydrogenase (GLDH/Chit-AA-CDs/SPCE). The morphology of GLDH/Chit-AA-CDs/SPCE platform was analysed by AFM at each different step of the electrode modification process. The resulting biosensing platform is capable of detect NADH enzymatically generated by GLDH in the presence of glutamate and NAD+. Good analytical parameters were obtained for glutamate analysis using GLDH/Chit-AA-CDs/SPCE, as LOD and LOQ of 3.3 and 11 µM, respectively. The biosensor has been successfully applied to the analysis of food and biological samplesThis work has been supported by the Spanish Ministerio de Ciencia e Innovacion (PID2020–116728RB-I00) and Comunidad Autonoma de Madrid (SI3/PJI/2021–00341, P2018/NMT-4349 TRANSNANOAVANSENS Program