Risky decision-making after exposure to a food-choice task in excess weight adolescents: Relationships with reward-related impulsivity and hunger

Objective To assess the effects of exposure to a food-choice task (appetizing versus healthy food) on risky decision-making by excess versus normal weight adolescents. We also analyzed the influence of food visualization on hunger levels, as well as group differences in food choices and impulsivity. Methods Fifty-six adolescents (aged 13–18 years) classified as excess (n = 27) or normal (n = 29) weight participated in the study. Risky-decision-making was assessed through the Balloon Analogue Risk Task, which was administered before and after a food-choice task. We also evaluated impulsivity traits through the UPPS-P Scale, and subjective hunger levels with a visual analogue scale. Results Adolescents with excess weight showed enhanced risky decision-making after the food-choice task compared to normal weight adolescents, as well as increased hunger levels. Furthermore, excess weight adolescents made more appetizing choices, and showed greater scores for Positive Urgency and Sensation Seeking. Reward-related impulsivity measures were positively associated with the number of appetizing choices in the food-choice task. Several associations were found between impulsivity measures, hunger levels and risk-taking variables. Conclusions Excess weight adolescents increased their risky-decision-making after food exposure and this augmentation was associated with the increase in hunger levels. Increased hunger levels and risk-taking after food exposure could lead to overeating. Alterations in decision-making caused by food signals may be a long-term risk factor for the development of obesity in adulthood. In modern societies, with the high availability and continuous exposure to food cues, decision-making may be a crucial factor in maintain healthy eating habits in adolescents

Exploración del T-learning y los Contenidos Digitales en el Contexto Educativo

La televisión digital terrestre (TDT), como tecnología que difunde televisión de mejor calidad y servicios con valor agregado a una amplia población a través del aire y de manera gratuita, ya está en funcionamiento en varios países del mundo, mientras en la mayoría de países latinoamericanos se encuentra en proceso de implementación y en espera del apagón analógico. Por esta razón, es necesario que los diversos sectores de la sociedad, como la academia, se preparen, conozcan, formen e impulsen el desarrollo de aplicaciones y contenidos para la televisión digital (TVD). En este artículo se presenta una contextualización de las aplicaciones para TVD, resaltando el t- learning para procesos de enseñanza/aprendizaje, los escenarios propuestos donde una universidad o institución académica pueden participar.Palabras clave: Televisión digital, gestión de contenidos digitales y aprendizaje virtual

Negative Social Evaluation Impairs Executive Functions in Adolescents With Excess Weight: Associations With Autonomic Responses.

Background Adolescents with excess weight suffer social stress more frequently than their peers with normal weight. Purpose To examine the impact of social stress, specifically negative social evaluation, on executive functions in adolescents with excess weight. We also examined associations between subjective stress, autonomic reactivity, and executive functioning. Methods Sixty adolescents (aged 13–18 years) classified into excess weight or normal weight groups participated. We assessed executive functioning (working memory, inhibition, and shifting) and subjective stress levels before and after the Trier Social Stress Task (TSST). The TSST was divided into two phases according to the feedback of the audience: positive and negative social evaluation. Heart rate and skin conductance were recorded. Results Adolescents with excess weight showed poorer executive functioning after exposure to TSST compared with adolescents with normal weight. Subjective stress and autonomic reactivity were also greater in adolescents with excess weight than adolescents with normal weight. Negative social evaluation was associated with worse executive functioning and increased autonomic reactivity in adolescents with excess weight. Conclusions The findings suggest that adolescents with excess weight are more sensitive to social stress triggered by negative evaluations. Social stress elicited deterioration of executive functioning in adolescents with excess weight. Evoked increases in subjective stress and autonomic responses predicted decreased executive function. Deficits in executive skills could reduce cognitive control abilities and lead to overeating in adolescents with excess weight. Strategies to cope with social stress to prevent executive deficits could be useful to prevent future obesity in this population

Salivary alpha-amylase mediates the increase in hunger levels in adolescents with excess weight after viewing food images

Background: Salivary alpha-amylase (sAA) initiates the digestion process in the mouth and its levels might influence feelings of hunger and the propensity toward obesity. This study aims to evaluate basal differences in sAA between adolescents with excess weight (EW) and normal weight (NW), and the associations between sAA levels and feelings of hunger after viewing food images. Methods: Adolescents (13–18 years old) classified as EW (n = 30) or NW (n = 30) participated in the study. Saliva samples were collected before the administration of a food-choice task. Hunger was evaluated before and after the food-choice task. Results: EW adolescents showed lower basal sAA levels than NW adolescents and a greater increase in hunger levels after viewing food images. In addition, sAA levels had a significant inverse relationship with the increase in hunger in EW adolescents, but not in NW adolescents. Finally, significant inverse associations between sAA, BMI, and body fat percentage were found. Conclusions: Levels of hunger and changes therein, after viewing food are dependent on sAA levels in EW adolescents. This finding indicates that sAA levels may be a mediator of feelings of hunger in individuals with overweight in the context of viewing food cues, suggesting the utility of the sAA enzyme as a marker of hunger and propensity toward obesity

Reliability, Factor Structure and Predictive Validity of the Widespread Pain Index and Symptom Severity Scales of the 2010 American College of Rheumatology Criteria of Fibromyalgia

©. This manuscript version is made available under the CC-BY license http://creativecommons.org/licenses/ccby/4.0/ This document is the Published, version of a Published Work that appeared in final form in [Journal of Clinical Medicine]. To access the final edited and published work see [https://doi.org/10.3390/jcm9082460]Fibromyalgia syndrome (FMS) is a chronic condition of widespread pain. In 2010, the American College of Rheumatology (ACR) proposed new diagnostic criteria for FMS based on two scales: the Widespread Pain Index (WPI) and Symptoms Severity (SS) scale. This study evaluated the reliability, factor structure and predictive validity of WPI and SS. In total, 102 women with FMS and 68 women with rheumatoid arthritis (RA) completed the WPI, SS, McGill Pain Questionnaire, Trait Anxiety Inventory, Fatigue Severity Scale, Oviedo Quality of Sleep Questionnaire, and Beck Depression Inventory. Pain threshold and tolerance and a measure of central sensitization to pain were obtained by pressure algometry. Values on WPI and SS showed negative-skewed frequency distributions in FMS patients, with most of the observations concentrated at the upper end of the scale. Factor analysis did not reveal single-factor models for either scale; instead, the WPI was composed of nine pain-localization factors and the SS of four factors. The Cronbach’s α (i.e., Internal consistency) was 0.34 for the WPI,0.83 for the SS and 0.82 for the combination of WPI and SS. Scores on both scales correlated positively with measures of clinical pain, fatigue, insomnia, depression, and anxiety but were unrelated to pain threshold and tolerance or central pain sensitization. The 2010 ACR criteria showed 100% sensitivity and 81% specificity in the discrimination between FMS and RA patients, where discrimination was better for WPI than SS. In conclusion, despite their limited reliability, both scales allow for highly accurate identification and differentiation of FMS patients. The inclusion of more painful areas in the WPI and of additional symptoms in the SS may reduce ceiling effects and improve the discrimination between patients differing in disease severity. In addition, the use of higher cut-off values on both scales may increase the diagnostic specificity in Spanish samples

Fiabilidad, validez factorial y datos normativos de la versión española del inventario abreviado de reacciones interpersonales (SIRI) de Grossarth-Maticek y Eysenck

Eysenck and Grossarth-Maticek’s model states that some of their personality types are predisposed to specific illnesses (Types 1 and 5 to cancer, and Type 2 to coronary heart disease), whereas others are preserved (Type 4) or not predisposed (Types 3 and 6). The aim of this study is to provide infor-mation as regards the reliability, factor validity and normative data of the Spanish version of Grossarth-Maticek and Eysenck´s Short Interpersonal Reactions Inventory (SIRI) in a sample of uni-versity students (N=425). The results indicate that 1) internal consistency is adequate (0,88-0,75); 2) factor analysis suggests that this instrument measures four dimensions: Factor 1 compounded by Types 1 and 2 (psychosomatic risk), Factor 2 constituted by Types 3 and 6 (hysteria/psychopathy), Factor 3 configured by Type 5 (rationality) and Factor 4 defined by Type 4 (autonomy); and 3) distribu-tion of personality types is similar to that found in prior studies with samples of young subjects.El modelo de Eysenck y Grossarth-Maticek postula que algunos de sus tipos de personalidad están predispuestos a enfermedades específicas (tipos 1 y 5 al cáncer, y tipo 2 a la enfermedad coronaria), mientras otros están preservados (tipo 4) o no predispuestos (tipos 3 y 6). El objetivo de este estudio ha sido aportar datos sobre la fiabilidad, validez factorial y baremación de la versión española del Inventario abreviado de reacciones interpersonales de Grossarth-Maticek y Eysenck (SIRI) en una muestra de estudiantes universitarios (n = 425). Los resultados indican 1) la aceptable consistencia interna (0,88-0,75); 2) el análisis factorial efectuado sugiere que el instrumento mide cuatro dimensio-nes: un primer factor está formado por los tipos 1 y 2 (riesgo psicosomático), un segundo factor está constituido por los tipos 3 y 6 (histeria/psicopatía), el tercer factor está configurado por el tipo 5 (ra-cionalidad) y el cuarto factor está definido por el tipo 4 (autonomía); y 3) la distribución de los tipos de personalidad es similar a la encontrada en estudios previos con muestras de sujetos jóvenes

APOBEC3G mRNA expression in exposed seronegative and early stage HIV infected individuals decreases with removal of exposure and with disease progression

<p>Abstract</p> <p>Background</p> <p>APOBEC3G is an antiretroviral factor that acts by inducing G to A mutations. In this study, we examined the expression of APOBEC3G in uninfected HIV-1 exposed individuals at the time of their partner's diagnosis and one year later. We then compared this expression with that of infected individuals at different disease stages. APOBEC3G mRNA was measured in PBMCs from three groups: healthy controls with no known risk factor to HIV infection (n = 26), exposed uninfected individuals who had unprotected sex with their HIV+ partners for at least 3 months (n = 37), and HIV infected patients at various disease stages (n = 45), including 8 patients with low HIV viral loads < 10,000 copies/mL (LVL) for at least 3 years. Additionally, we obtained sequences from the env, gag, pol, nef, vif and the LTR of the patients' virus.</p> <p>Results</p> <p>Exposed uninfected individuals expressed higher APOBEC3G than healthy controls (3.86 vs. 1.69 relative expression units), and their expression significantly decreased after a year from the HIV diagnosis and subsequent treatment of their partners. Infected individuals showed a positive correlation (Rho = 0.57, p = 0.00006) of APOBEC3G expression with CD4+ T cell count, and a negative correlation with HIV viremia (Rho = -0.54, p = 0.00004). The percentage of G to A mutations had a positive correlation (Rho = 0.43, p = 0.0226) with APOBEC3G expression, and it was higher in LVL individuals than in the other patients (IQR 8.27 to 9.64 vs. 7.06 to 8.1, p = 0.0084). Out of 8 LVLs, 3 had hypermutations, and 4 had premature stop codons only in viral <it>vif</it>.</p> <p>Conclusion</p> <p>The results suggest that exposure to HIV may trigger APOBEC3G expression in PBMCs, in the absence of infection. Additionally, cessation of exposure or advanced disease is associated with decreased APOBEC3G expression.</p

Covariate effects of resting heart rate variability on affective ratings and startle reflex during cognitive reappraisal of negative emotions

Heart Rate Variability (HRV) has been widely studied in laboratory settings due to its clinical implications, primarily as a potential biomarker of emotion regulation (ER). Studies have reported that individuals with higher resting HRV show more distinct startle reflexes to negative stimuli as compared to those with lower HRV. These responses have been associated with better defense system function when managing the context demands. There is, however, a lack of empirical evidence on the association between resting HRV and eyeblinks during laboratory tasks using instructed ER. This study explored the influence of tonic HRV on voluntary cognitive reappraisal through subjective and startle responses measured during an independent ER task. In total, 122 healthy participants completed a task consisting of attempts to upregulate, downregulate, or react naturally to emotions prompted by unpleasant pictures. Tonic HRV was measured for 5 minutes before the experiment began. Current results did not support the idea that self-reported and eyeblink responses were influenced by resting HRV. These findings suggest that, irrespective of resting HRV, individuals may benefit from strategies such as reappraisal that are useful for managing negative emotions. Experimental studies should further explore the role of individual differences when using ER strategies during laboratory task

Impact of the noise on the emulated grid voltage signal in hardware-in-the-loop used in power converters

This work evaluates the impact of the input voltage noise on a Hardware-In-the-Loop (HIL) system used in the emulation of power converters. A poor signal-to-noise ratio (SNR) can compromise the accuracy and precision of the model, and even make certain techniques for building mathematical models unfeasible. The case study presents the noise effects on a digitally controlled totem-pole converter emulated with a low-cost HIL system using an FPGA. The effects on the model outputs, and the cost and influence of different hardware implementations, are evaluated. The noise of the input signals may limit the benefits of increasing the resolution of the model.This research was funded by the Spanish Ministry of Science and Innovation under Project PID2021-128941OB-I00 TRENTI–Efficient Energy Transformation in Industrial Environment

Increased food choice-evoked brain activation in adolescents with excess weight: Relationship with subjective craving and behavior

Objective We used functional magnetic resonance imaging (fMRI) to assess brain regions associated with food choices between appetizing (i.e., high sugar, high fat) and plain food in adolescents with excess weight and those with normal weight. The associations between choice-evoked brain activation and subjective food craving and behavioral food choices were also evaluated. Methods Seventy-three adolescents (aged 14–19 years), classified into excess weight (n = 38) or normal weight (n = 39) groups, participated in the study. We used a food-choice fMRI task, between appetizing and plain food, to analyse brain activation differences between groups. Afterwards, participants assessed their "craving" for each food presented in the scanner. Results Adolescents with excess weight showed higher brain activation in frontal, striatal, insular and mid-temporal regions during choices between appetizing and standard food cues. This pattern of activations correlated with behavioral food choices and subjective measures of craving. Conclusions Our findings suggest that adolescents with excess weight have greater food choice-related brain reactivity in reward-related regions involved in motivational and emotional responses to food. Increased activation in these regions is generally associated with craving, and increased dorsolateral prefrontal cortex is specifically associated with appetizing food choices among adolescents with excess weight, which may suggest greater conflict in these decisions. These overweight- and craving-associated patterns of brain activation may be relevant to decision-making about food consumption