A wearable dialysis device: the first step to continuous therapy

A wearable haemodialysis device holds the promise of freedom for patients to carry on with their lives without the limitations associated with conventional dialysis. A new report of the outcomes of 24 h treatment with a wearable haemodialysis system represents a small but important step forward in the development of a wearable device

Analysis of On-Chip Clock Distribution Systems in High Speed Systems

Coordinated Science Laboratory was formerly known as Control Systems LaboratoryNational Science Foundation / NSF CDR 85-22666IBM Fellowshi

El moderno sistema de tributación de los bienes inmuebles

Taxation has long been an integral part of the functioning of the state, and if earlier the so-called “taxes” were used exclusively for the ruling elite and the bureaucratic apparatus, today taxes, forming the state budget revenue item, are subsequently redistributed to support programs various spheres of society, be it medicine, education, science, etc. The article is devoted to the study of the modern system of taxation of real estate, in particular, the specific features of real estate as objects of taxation, the main types of property taxes, regulatory legal acts in the field of taxation, as well as the advantages and disadvantages of the tax structure of the Russian Federation.Los impuestos han sido durante mucho tiempo una parte integral del funcionamiento del estado, y si antes los llamados «impuestos» se usaban exclusivamente para la élite gobernante y el aparato burocrático, hoy los impuestos, que forman la partida de ingresos del presupuesto estatal, se redistribuyen posteriormente a programas de apoyo en diversas esferas de la sociedad, ya sea medicina, educación, ciencia, etc. El artículo está dedicado al estudio del sistema moderno de tributación de bienes inmuebles, en particular, las características específicas de los bienes inmuebles como objetos impositivos, los principales tipos de impuestos a la propiedad, actos legales regulatorios en el campo de los impuestos, así como las ventajas y desventajas de la estructura tributaria de la Federación de Rusia

Desenvolvimento inovador de construção na rússia: economia, tecnologias, gestão

The main directions of innovative development of the construction industry in the views of different authors are considered. From the perspective of the state programs “Innovative Russia - 2020” and “Strategy for the Scientific and Technological Development of the Russian Federation”, proposals were developed to make the innovation process on improving technologies, organization and management of construction industry more orderly and systematic. The system-synergistic and cluster approaches to the formation of innovative practices in capital construction based on the use of BIM-technologies have been substantiated.Se consideran las principales direcciones de desarrollo innovador de la industria de la construcción en las opiniones de diferentes autores. Desde la perspectiva de los programas estatales “Rusia innovadora - 2020” y “Estrategia para el desarrollo científico y tecnológico de la Federación de Rusia”, se desarrollaron propuestas para hacer que el proceso de innovación para mejorar las tecnologías, la organización y la gestión de la industria de la construcción sea más ordenado y sistemático. Los enfoques de sinergia de sistemas y de grupos para la formación de prácticas innovadoras en la construcción de capital basada en el uso de tecnologías BIM se han comprobado.As direções principais do desenvolvimento inovador da indústria de construção nas visões de autores diferentes são consideradas. Do ponto de vista dos programas estaduais “Rússia inovadora - 2020” e “Estratégia para o desenvolvimento científico e tecnológico da Federação Russa”, foram desenvolvidas propostas para tornar o processo de inovação na melhoria das tecnologias, organização e gestão da indústria da construção civil mais ordenada e sistemática. As abordagens sinérgicas do sistema e cluster para a formação de práticas inovadoras na construção do capital com base no uso de tecnologias BIM foram comprovadas

Utilizarea angioplastiei transluminale în urologie

Summary. During last years urology demonstrates considerable successes, the endovascular surgery is the most outstanding example in this sense. Owing this method many classic operations were replaced by less invasive once. The principle of the method is in dilatation of the stenosed zone of the artery, the approach to this artery is realized by the percutaneus punction of a single peripheral artery. We have applied the endovascular endoplasty in three cases

Reverse mathematics of matroids

Matroids generalize the familiar notion of linear dependence from linear algebra. Following a brief discussion of founding work in computability and matroids, we use the techniques of reverse mathematics to determine the logical strength of some basis theorems for matroids and enumerated matroids. Next, using Weihrauch reducibility, we relate the basis results to combinatorial choice principles and statements about vector spaces. Finally, we formalize some of the Weihrauch reductions to extract related reverse mathematics results. In particular, we show that the existence of bases for vector spaces of bounded dimension is equivalent to the induction scheme for \Sigma^0_2 formulas

Impact of water hardness on oxytetracycline oral bioavailability in fed and fasted piglets

Water hardness is a critical factor that affects oxytetracycline dissolution by chelation with cations. These interactions may lead to impaired dosing and consequently decrease absorption. Moreover, feed present in gastrointestinal tract may interact with antibiotic and alter pharmacokinetic parameters. In the present study, dissolution profiles of an oxytetracycline veterinary formulation were assessed in purified, soft and hard water. Furthermore, oxytetracycline absolute bioavailability, after oral administration of the drug dissolved in soft or hard water, was evaluated in fed and fasted piglets. A maximum dissolution of 86% and 80% was obtained in soft and hard water, respectively, while in purified water dissolution was complete. Results from in vivo study reconfirmed oxytetracycline´s very low oral bioavailability. The greatest values were attained when antibiotic was dissolved in soft water and in fasted animals. Statistically significant lower absolute bioavailability was achieved when hard water was used and/or animals were fed. Moreover, Cmax attained in all treatments was lower than MIC90 of most important swine pathogens. For these reasons, the oral use of OTC formulations, that have demonstrated low oral bioavailability, should be avoided to treat systemic diseases in pigs.Fil: Decundo, Julieta María. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencia Veterinarias. Departamento de Fisiopatología. Laboratorio de Toxicología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; ArgentinaFil: Dieguez, Susana Nelly. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencia Veterinarias. Departamento de Fisiopatología. Laboratorio de Toxicología; Argentina. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; ArgentinaFil: Martínez, Guadalupe. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Fisiopatología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; ArgentinaFil: Romanelli, Agustina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Fisiopatología; ArgentinaFil: Fernández Paggi, María Belén. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Fisiopatología; ArgentinaFil: Pérez, Denisa Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Fisiopatología; ArgentinaFil: Amanto, Fabian A.. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Producción Animal; ArgentinaFil: Soraci, Alejandro Luis. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencia Veterinarias. Departamento de Fisiopatología. Laboratorio de Toxicología; Argentin

Citizen Science in Archaeology : Developing a Collaborative Web Service for Archaeological Finds in Finland

Peer reviewe

Repeated revascularization in the aorto-femoral segment

Scopul lucrării. În ultimii ani structura intervențiilor repetate în segmentul aorto-ilio- femural a suferit schimbări esențiale datorită implementării metodelor endovasculare pe scara largă. Intervențiile primare au putut fi bypass-uri și/sau angioplastii cu stentare, iar intervențiile repetate pot fi deschise, endovasculare sau hibride. Scopul lucrării este aprecierea posibilităților metodelor chirurgicale clasice, endovasculare și hibride cu implementarea unor gesturi chirurgicale noi pentru îmbunătățirea rezultatelor. Materiale și metode. În perioada anilor 2009-2022 s-au efectuat 439 intervenții de revascularizare repetată în segmentul aorto-iliofemural la 378 pacienți cu ocluzii sau stenoze severe ale segmentului revascularizat în antecedente, cât și cu anevrisme anastomotice. Rezultate. Letalitatea postoperatorie a fost de 2,7 %, iar rata amputațiilor înalte de 5%. Concluzii. Datorită implementării metodelor endovasculare și hibride apar noi posibilități în revascularizarea repetată în segmentul aorto-femural. La minimalizarea traumatismului chirurgical și a ratei complicațiilor contribuie și folosirea bypass-urilor extraanatomice, protezarea distală a a. femurale profunde și anume perfectarea acestor tehnici.Aim of study. In recent years, the structure of repeated interventions in the aorto-ilio-femoral segment has undergone significant changes due to the widespread implementation of endovascular methods. Primary interventions can involve bypasses and/or angioplasty with stenting, while repeated interventions can be open, endovascular, or hybrid. The objective of the study is to assess the possibilities of classical surgical, endovascular, and hybrid methods with the implementation of new surgical techniques to improve outcomes. Materials and methods. Between 2009 and 2022, 439 repeated revascularization procedures were performed in the aorto-iliofemoral segment on 378 patients with previous severe occlusions or stenoses of the revascularized segment, as well as anastomotic aneurysms. Results. The postoperative mortality rate was 2.7%, and the rate of major amputations was 5%. Conclusions. Due to the implementation of endovascular and hybrid methods, new possibilities arise for repeated revascularization in the aorto-femoral segment. Minimizing surgical trauma and complication rates is facilitated by the use of extra-anatomic bypasses, distal prosthetic grafting of the deep femoral artery, and the refinement of these techniques