Effect of Glycoprotein C on the Extracellular Stability of HSV-1 Virions

Faculty advisor: Stephen RiceThis research was supported by the Undergraduate Research Opportunities Program (UROP)

Magnetic Proximity induced efficient charge-to-spin conversion in large area PtSe2_{2}/Ni80_{80}Fe20_{20} heterostructures

As a topological Dirac semimetal with controllable spin-orbit coupling and conductivity, PtSe$_2$, a transition-metal dichalcogenide, is a promising material for several applications from optoelectric to sensors. However, its potential for spintronics applications is yet to be explored. In this work, we demonstrate that PtSe$_{2}$/Ni$_{80}$Fe$_{20}$ heterostructure can generate a large damping-like current-induced spin-orbit torques (SOT), despite the absence of spin-splitting in bulk PtSe$_{2}$. The efficiency of charge-to-spin conversion is found to be $(-0.1 \pm 0.02)$~nm$^{-1}$ in PtSe$_{2}$/Ni$_{80}$Fe$_{20}$, which is three times that of the control sample, Ni$_{80}$Fe$_{20}$/Pt. Our band structure calculations show that the SOT due to the PtSe$_2$ arises from an unexpectedly large spin splitting in the interfacial region of PtSe$_2$ introduced by the proximity magnetic field of the Ni$_{80}$Fe$_{20}$ layer. Our results open up the possibilities of using large-area PtSe$_{2}$ for energy-efficient nanoscale devices by utilizing the proximity-induced SOT.Comment: 18 pages, 4 figure

Osteoma of frontal sinus

Osteomas are benign, slow-growing tumors found commonly in craniomaxillofacial region. Clinically, they may remain asymptomatic because of their small size or may become symptomatic because of enlargement, erosion, or compression of structures in the vicinity. Treatment is needed in frontal sinus osteomas causing symptoms or having immediate potential to cause complications. The treatment approach can be closed or open depending on the size, location, and frontal recess area occupied by the tumor. We present two cases of frontal sinus osteoma with varied presentations at the two ends of clinical spectrum and discuss the management protocols

Evaluation of different visual method used, to enhance communication skills between dental care providers and speech and hearing impaired patients

Purpose: The purpose of this study is to evaluate the efficacy and retentiveness of various communication methods among speech and hearing impaired patients and dental practitioners. Materials and Methods: A group of 33 school participants were selected for this study. An experimental task required the participants to follow routine dental instructions in the form of videotape and photographic charts and answer the questionnaire based on visual instructions. School participants were visited two times at an interval of 1 month. Participants were randomly divided into three groups, each consisting of 11 school participants, irrespective of gender and age. Group 1 received visual instructions without showing video and charts, Group 2 received video instructions, and Group 3 received photographic instructions. The questionnaires were assessed immediately and after 1 month. Results: The study results were assessed in terms of improvement in knowledge concerning communication skills and long-term retention of the instructions for 1 month. ANOVA followed by post hoc Tukey test revealed a significant difference between Group 1 and other groups. However, there was no statistically significant difference between Group 2 and Group 3. The paired t-test revealed that there was a significant difference between the two visits in Group 1. However, there was no significant difference between visit 1 and visit 2 in Group 2 and Group 3. Conclusion: Health-care workers and patients with special needs like hearing-impaired patients should overcome communication barriers that may hinder proper diagnosis and treatment planning

Data privacy in healthcare: In the era of artificial intelligence

Data Privacy has increasingly become a matter of concern in the era of large public digital respositories of data. This is particularly true in healthcare where data can be misused if traced back to patients, and brings with itself a myriad of possibilities. Bring custodians of data, as well as being at the helm of disigning studies and products that can potentially benefit products, healthcare professionals often find themselves unsure about ethical and legal constraints that undelie data sharing. In this review we touch upon the concerns, leal frameworks as well as some common practices in these respects

Magnetodynamic properties of ultrathin films of Fe 3_{\textbf{3}} 3 Sn 2_{\textbf{2}} 2 -a topological kagome ferromagnet

Abstract Fe $$_3$$ 3 Sn $$_{2}$$ 2 is a topological kagome ferromagnet that possesses numerous Weyl points close to the Fermi energy, which can manifest various unique transport phenomena such as chiral anomaly, anomalous Hall effect, and giant magnetoresistance. However, the magnetodynamic properties of Fe $$_3$$ 3 Sn $$_{2}$$ 2 have not yet been explored. Here, we report, for the first time, the measurements of the intrinsic Gilbert damping constant ( $$\alpha _\text{int}$$ α int ), and the effective spin mixing conductance (g $$_\text{eff}^{\uparrow \downarrow }$$ eff ↑ ↓ ) of Pt/Fe $$_3$$ 3 Sn $$_2$$ 2 bilayers for Fe $$_3$$ 3 Sn $$_{2}$$ 2 thicknesses down to 2 nm, for which $$\alpha _\text{int}$$ α int is $$(3.8 \pm 0.2) \times 10^{-2}$$ ( 3.8 ± 0.2 ) × 10 - 2 , and g $$_\text{eff}^{\uparrow \downarrow }$$ eff ↑ ↓ is $$(11.7 \pm 0.6)~\text{nm}^{-2}$$ ( 11.7 ± 0.6 ) nm - 2 . The films have a high saturation magnetization, $$M_\text{S}=620~\mathrm{emu~cm^{-3}}$$ M S = 620 emu cm - 3 , and large anomalous Hall coefficient, $$R_\text{S}=4.6\times 10^{-10}~{\Omega ~\rm cm~G^{-1}}$$ R S = 4.6 × 10 - 10 Ω cm G - 1 . The large values of g $$_\text{eff}^{\uparrow \downarrow }$$ eff ↑ ↓ , together with the topological properties of Fe $$_3$$ 3 Sn $$_2$$ 2 , make Fe $$_3$$ 3 Sn $$_2$$ 2 /Pt bilayers useful heterostructures for the study of topological spintronic devices

Familial co-segregation and the emerging role of long-read sequencing to re-classify variants of uncertain significance in inherited retinal diseases

Abstract Phasing genetic variants is essential in determining those that are potentially disease-causing. In autosomal recessive inherited retinal diseases (IRDs), reclassification of variants of uncertain significance (VUS) can provide a genetic diagnosis in indeterminate compound heterozygote cases. We report four cases in which familial co-segregation demonstrated a VUS resided in trans to a known pathogenic variant, which in concert with other supporting criteria, led to the reclassification of the VUS to likely pathogenic, thereby providing a genetic diagnosis in each case. We also demonstrate in a simplex patient without access to family members for co-segregation analysis that targeted long-read sequencing can provide haplotagged variant calling. This can elucidate if variants reside in trans and provide phase of genetic variants from the proband alone without parental testing. This emerging method can alleviate the bottleneck of haplotype analysis in cases where genetic testing of family members is unfeasible to provide a complete genetic diagnosis

Interfacial Origin of Unconventional Spin-Orbit Torque in Py/γ−IrMn3

Angle-resolved spin-torque ferromagnetic resonance measurements are carried out in heterostructures consisting of Py (Ni81Fe19) and a noncollinear antiferromagnetic quantum material γ- IrMn3. The structural characterization reveals that γ- IrMn3 is polycrystalline in nature. A large exchange bias of 158 Oe is found in Py/γ- IrMn3 at room temperature, while γ- IrMn3/Py and Py/Cu/γ- IrMn3 exhibit no exchange bias. Regardless of the exchange bias and stacking sequence, a substantial unconventional out-of-plane anti-damping torque is observed when γ- IrMn3 is in direct contact with Py. The magnitude of the out-of-plane spin-orbit torque efficiency is found to be twice as large as the in-plane spin-orbit torque efficiency. The unconventional spin-orbit torque vanishes when a Cu spacer is introduced between Py and γ- IrMn3, indicating that the unconventional spin-orbit torque in this system originates at the interface. These findings are important for realizing efficient antiferromagnet-based spintronic devices via interfacial engineering