How the Law Thinks: Toward a Constructivist Epistemology of Law

Tradução para o português a partir de original em inglês (original: TEUBNER, G. How the Law Thinks: Toward a Constructivist Epistemology of Law. Law & Society Review, [s. l.], v. 23, n. 5, p. 727-757, 1989. doi:10.2307/3053760) [N. do E.].Translation to Brazilian Portuguese from the original in English (original: TEUBNER, G. How the Law Thinks: Toward a Constructivist Epistemology of Law. Law & Society Review, [s. l.], v. 23, n. 5, p. 727-757, 1989. doi:10.2307/3053760) [N. do E.]

Determining the Feasibility of Milk Vending Machines to Improve Calcium Intake Among College Students

Calcium intake declines from late adolescence to young adulthood, in part, due to decreases in accessibility to milk and dairy products. While milk vending has shown demonstrated success in secondary schools, no studies have examined whether milk vending improves calcium intake among college students. We hypothesized that milk and calcium intake would be higher among college students given access to milk vending in their dormitory (milk vending consumers) compared to those lacking access in their dormitory (non-milk vending consumers). Milk vending machines were installed in two dormitories, and two dormitories having non-milk beverage vending served as comparison sites. Students completed a calcium intake questionnaire at the point of milk (n = 73) or non-milk (n = 79) beverage vending purchases. Mean total calcium intake was higher in milk vending consumers (1245 + 543 mg/d) compared to non-milk vending consumers (1042 + 447 mg/d) (p = 0.01). Adjusting for gender and milk vending consumer status, there was a positive association between past month milk vending purchases and daily calcium intake from milk (p \u3c 0.001). Fiftyseven students without in-dormitory access to milk vending reported an interest in milk vending if made available. Milk vending may serve as a novel approach

Parents\u27 Calcium Knowledge Is Associated with Parental Practices to Promote Calcium Intake Among Parents of Early Adolescent Children

The study reported here aimed to identify the relationship of parents\u27 calcium knowledge with diet-related parental practices and determinants of calcium knowledge. A cross-sectional survey was conducted measuring parental practices, calcium knowledge, and demographics. A convenience sample of 599 racially/ethnically diverse parents of children 10-13y completed questionnaires. Higher education and having a daughter were associated with higher calcium knowledge; being Asian or Hispanic and born outside the U.S. were associated with lower calcium knowledge. Parents with greater calcium knowledge were more likely to engage in healthy parenting practices. These factors may be important considerations for Extension educators in nutrition education

The Servitization of European Manufacturing Industries

This paper provides new evidence for the servitization of European manufacturing – the trend that manufacturing firms increasingly offer services along with their physical products. We employ input-output data as well as data from a company survey to give a comprehensive picture of servitization across countries and industries. The share of services in the output of manufacturing industries increased in the large majority of European countries between 1995 and 2005 and between 2000 and 2005. Service output of manu-facturing, however, is still small compared to the output of physical products. The highest service shares are found in small countries with a high degree of openness and R&D intensity. EU-12 Member States have lower shares of service output compared to the EU-15. There is a strong link between servitization and technological innovation at different levels. Countries with the highest shares of services on manufacturing output have also the highest R&D intensities at the aggregate level. The service output of these countries consists predominantly of knowledge-intensive services. Highly innovative sectors reveal also the highest share of firms that offer services and the highest turnover generated with services. Examples are electrical and optical equipment, machinery, or the chemical and pharmaceutical industry. At the firm level, we find a U-shaped relationship between firm size and service output, which indicates that small, but also large manufacturing firms have advantages in servitization. Producers of complex, customized products tend to have a higher share of services in output than producers of simple, mass-produced goods. Moreover, firms which have launched products new to the market during the last two years are more likely to realize higher shares of turnover from services compared to companies which launched no products new to the market

The Servitization of European Manufacturing Industries

This paper provides new evidence for the servitization of European manufacturing – the trend that manufacturing firms increasingly offer services along with their physical products. We employ input-output data as well as data from a company survey to give a comprehensive picture of servitization across countries and industries. The share of services in the output of manufacturing industries increased in the large majority of European countries between 1995 and 2005 and between 2000 and 2005. Service output of manu-facturing, however, is still small compared to the output of physical products. The highest service shares are found in small countries with a high degree of openness and R&D intensity. EU-12 Member States have lower shares of service output compared to the EU-15. There is a strong link between servitization and technological innovation at different levels. Countries with the highest shares of services on manufacturing output have also the highest R&D intensities at the aggregate level. The service output of these countries consists predominantly of knowledge-intensive services. Highly innovative sectors reveal also the highest share of firms that offer services and the highest turnover generated with services. Examples are electrical and optical equipment, machinery, or the chemical and pharmaceutical industry. At the firm level, we find a U-shaped relationship between firm size and service output, which indicates that small, but also large manufacturing firms have advantages in servitization. Producers of complex, customized products tend to have a higher share of services in output than producers of simple, mass-produced goods. Moreover, firms which have launched products new to the market during the last two years are more likely to realize higher shares of turnover from services compared to companies which launched no products new to the market

Monitoraggio Ambientale di un'Area Contaminata nella Provincia di Pavia

Lo scopo di tale indagine è stato quello di valutare il livello di contaminazione, l'estensione e l'entità di contaminanti presenti nei suoli superficiali a suo tempo riscontrati mediante il Progetto Pavia. Il monitoraggio ambientale ha interessato un'area di circa 12 ettari che si trova nel comune di Carpiano. Complessivamente sono state identificate 33 aree di campionamento dove sono stati prelevati campioni di suolo sino alla profondità di 30 cm. In ciascun campione di suolo, dopo adeguati trattamenti, è stata valutata la concentrazione di metalli pesanti, metalloidi, macroelementi, sostanza organica, pH, densità apparente, contenuto d'acqua. In alcuni campioni, precisamente 11, si è analizzata la concentrazione di diossine e furani e si è approntato uno studio che ha visto l'utilizzo dei batteri e dei loro prodotti. Lo studio condotto attraverso l'uso dei batteri ha evidenziato anomalie in alcuni punti ad elevata contaminazione. I risultati analitici ottenuti hanno identificato la presenza di una importante contaminazione di metalli pesanti, metalloidi, diossine e furani che interessa un area di alcuni ettari. Tale livello di contaminazione, per la presenza di sostanza organica e per valori ridotti di acidità dei suoli stessi, potrà arrecare danni ingenti all'ambiente.JRC.DDG.H.7-Land management and natural hazard

Space use of African wild dogs in relation to other large carnivores

Interaction among species through competition is a principle process structuring ecological communities, affecting behavior, distribution, and ultimately the population dynamics of species. High competition among large African carnivores, associated with extensive diet overlap, manifests in interactions between subordinate African wild dogs (Lycaon pictus) and dominant lions (Panthera leo) and spotted hyenas (Crocuta crocuta). Using locations of large carnivores in Hluhluwe-iMfolozi Park, South Africa, we found different responses from wild dogs to their two main competitors. Wild dogs avoided lions, particularly during denning, through a combination of spatial and temporal avoidance. However, wild dogs did not exhibit spatial or temporal avoidance of spotted hyenas, likely because wild dog pack sizes were large enough to adequately defend their kills. Understanding that larger carnivores affect the movements and space use of other carnivores is important for managing current small and fragmented carnivore populations, especially as reintroductions and translocations are essential tools used for the survival of endangered species, as with African wild dogs.The Smithsonian Institution Undersecretary for Science Endowment Funds, the American Zoo and Aquarium Association Conservation Endowment Fund, and Humboldt State University Sponsored Program Foundation (MSG); University of Pretoria, The Green Trust (WWFSA), and Bateleurs and Wildlife Conservation Trust (KZN) (MS); NRF, NSF, University of KwaZulu-Natal, Walt Disney Foundation and MGM, Wild about Cats, and Hluhluwe Tourism Association (RS); and THRIP (N. Ferguson) and Grand Hotel grants (C. Packer).http://www.plosone.orgam201

Three-dimensional morphology and gene expression in the Drosophila blastoderm at cellular resolution I: data acquisition pipeline

BACKGROUND: To model and thoroughly understand animal transcription networks, it is essential to derive accurate spatial and temporal descriptions of developing gene expression patterns with cellular resolution. RESULTS: Here we describe a suite of methods that provide the first quantitative three-dimensional description of gene expression and morphology at cellular resolution in whole embryos. A database containing information derived from 1,282 embryos is released that describes the mRNA expression of 22 genes at multiple time points in the Drosophila blastoderm. We demonstrate that our methods are sufficiently accurate to detect previously undescribed features of morphology and gene expression. The cellular blastoderm is shown to have an intricate morphology of nuclear density patterns and apical/basal displacements that correlate with later well-known morphological features. Pair rule gene expression stripes, generally considered to specify patterning only along the anterior/posterior body axis, are shown to have complex changes in stripe location, stripe curvature, and expression level along the dorsal/ventral axis. Pair rule genes are also found to not always maintain the same register to each other. CONCLUSION: The application of these quantitative methods to other developmental systems will likely reveal many other previously unknown features and provide a more rigorous understanding of developmental regulatory networks

Three-dimensional morphology and gene expression in the Drosophila blastoderm at cellular resolution I: data acquisition pipeline

BACKGROUND: To model and thoroughly understand animal transcription networks, it is essential to derive accurate spatial and temporal descriptions of developing gene expression patterns with cellular resolution. RESULTS: Here we describe a suite of methods that provide the first quantitative three-dimensional description of gene expression and morphology at cellular resolution in whole embryos. A database containing information derived from 1,282 embryos is released that describes the mRNA expression of 22 genes at multiple time points in the Drosophila blastoderm. We demonstrate that our methods are sufficiently accurate to detect previously undescribed features of morphology and gene expression. The cellular blastoderm is shown to have an intricate morphology of nuclear density patterns and apical/basal displacements that correlate with later well-known morphological features. Pair rule gene expression stripes, generally considered to specify patterning only along the anterior/posterior body axis, are shown to have complex changes in stripe location, stripe curvature, and expression level along the dorsal/ventral axis. Pair rule genes are also found to not always maintain the same register to each other. CONCLUSION: The application of these quantitative methods to other developmental systems will likely reveal many other previously unknown features and provide a more rigorous understanding of developmental regulatory networks

HDL-related biomarkers are robust predictors of survival in patients with chronic liver failure

Abstract Background & Aims The occurrence of acute decompensation (AD) worsens the prognosis of advanced chronic liver disease (ACLD). Various insults leading to increased systemic inflammation trigger acute-on-chronic liver failure (ACLF) with dramatically increased short-term mortality. During acute conditions such as sepsis, high-density lipoprotein cholesterol (HDL-C) levels decrease rapidly and HDL particles undergo profound changes in their composition and function. Indices of HDL quantity and quality may therefore associate with progression and survival in patients with advanced liver disease. Methods We studied levels of HDL-cholesterol (HDL-C), its subclasses HDL2-C and HDL3-C, and apolipoprotein(apo)A-I as indices of HDL quantity and HDL cholesterol efflux capacity as a metric of HDL functionality in 508 patients with compensated or decompensated cirrhosis including ACLF and 40 age- and gender-matched controls. Results Baseline levels of HDL-C and apoA-I were significantly lower in stable cirrhosis compared to control and further decreased in AD and ACLF . In stable cirrhosis (n=228), both HDL-C and apoA-I predicted the development of liver-related complications independently of MELD. In patients with AD with or without ACLF (n=280) both HDL-C and apoA-I were MELD-independent predictors of 90-day mortality. On ROC analysis, high diagnostic accuracies for 90-day mortality in AD patients were found for HDL-C (AUROC 0.79 ) and apoA-I (AUROC 0.80 ), very similar to that of MELD (AUROC 0.81 ). On Kaplan-Meier analysis, HDL-C 17 mg/dl and apoA-I 50 mg/dl indicated poor short-term survival. The prognostic accuracy of HDL-C was validated in a large external validation cohort of 985 patients with portal hypertension due to ACLD (AUROCs HDL-C: 0.81 vs. MELD: 0.77). Conclusion HDL-related biomarkers are robust predictors of disease progression and survival in chronic liver failure