Intelligent wargaming approach to increase course of action effectiveness in military operations

In this study, an intelligent wargaming approach is proposed to evaluate the effectiveness of a military operation plan in terms of operational success and survivability of the assets. The proposed application is developed based on classical military decision making and planning (MDMP) workflow for ease of implementation into the real-world applications. Contributions of this study are threefold; a) developing an intelligent wargaming approach to accelerate the course of action (COA) analysis step in the MDMP which leads creating more candidate COAs for a military operation, b) generating effective tactics against the opposite forces to increase operational success, and c) developing an efficient, visual wargame-based MDMP framework for future systems that require a small team of operators to supervise a network of automated agents. Several example engagement scenarios are performed to evaluate the system capabilities and results are given. Moreover, fleet composition issue for automated agents is investigated and the fleet composer algorithm with hyperparameter tuning architecture is proposed

AMU-LED Cranfield flight trials for demonstrating the advanced air mobility concept

Advanced Air Mobility (AAM) is a concept that is expected to transform the current air transportation system and provide more flexibility, agility, and accessibility by extending the operations to urban environments. This study focuses on flight test, integration, and analysis considerations for the feasibility of the future AAM concept and showcases the outputs of the Air Mobility Urban-Large Experimental Demonstration (AMU-LED) project demonstrations at Cranfield University. The purpose of the Cranfield demonstrations is to explore the integrated decentralized architecture of the AAM concept with layered airspace structure through various use cases within a co-simulation environment consisting of real and simulated standard-performing vehicle (SPV) and high-performing vehicle (HPV) flights, manned, and general aviation flights. Throughout the real and simulated flights, advanced U-space services are demonstrated and contingency management activities, including emergency operations and landing, are tested within the developed co-simulation environment. Moreover, flight tests are verified and validated through key performance indicator analysis, along with a social acceptance study. Future recommendations on relevant industrial and regulative activities are provided.European Union funding: 10101770

The development of an advanced air mobility flight testing and simulation infrastructure

The emerging field of Advanced Air Mobility (AAM) holds great promise for revolutionizing transportation by enabling the efficient, safe, and sustainable movement of people and goods in urban and regional environments. AAM encompasses a wide range of electric vertical take-off and landing (eVTOL) aircraft and infrastructure that support their operations. In this work, we first present a new airspace structure by considering different layers for standard-performing vehicles (SPVs) and high-performing vehicles (HPVs), new AAM services for accommodating such a structure, and a holistic contingency management concept for a safe and efficient traffic environment. We then identify the requirements and development process of a testing and simulation infrastructure for AAM demonstrations, which specifically aim to explore the decentralized architecture of the proposed concept and its use cases. To demonstrate the full capability of AAM, we develop an infrastructure that includes advanced U-space services, real and simulated platforms that are suitable for future AAM use cases such as air cargo delivery and air taxi operations, and a co-simulation environment that allows all of the AAM elements to interact with each other in harmony. The considered infrastructure is envisioned to be used in AAM integration-related efforts, especially those focusing on U-space service deployment over a complex traffic environment and those analyzing the interaction between the operator, the U-space service provider (USSP), and the air traffic controller (ATC).European Union funding: 10101770

Cerebral venous thrombosis as a complication of leptospirosis

Leptospirosis is an acute infectious disease caused by a spirochete of the leptospira gender and it is characterized by severe vasculitis. It is not common for leptospirosis to present as a primary neurological disease. On the other hand, no study has been reported on the progression of cerebral venous thrombosis (CVT) in patients with leptospirosis so far. This is the first case reported which shows CVT as a complication after the leptospirosis infection. An acutely developed leptospirosis and post-infectious CVT in a 21-year-old soldier is described here. (C) 2006 The British Infection Society. Published by Elsevier Ltd. All rights reserved

Pregnancy and its outcomes in hemodialysis patients in Turkey

Background/aim: This study aimed to investigate pregnancy frequency and evaluate the factors affecting live births in hemodialysis (HD) patients. Materials and methods: Female HD patients whose pregnancy was retrospectively reported between January 1, 2014, and December 31, 2019. The duration of HD, primary disease, and the information on whether the pregnancy resulted in abortion, stillbirth, or live birth, whether the HD duration was prolonged after diagnosing the pregnancy and whether it accompanied preeclampsia were recorded. Results: In this study, we reached 9038 HD female patients' data in the study. A total of 235 pregnancies were detected in 145 patients. The mean age was 35.42 (35 +/- 7.4) years. The mean age at first gestation was 30.8 +/- 6.5 years. The average birth week was 32 (28 -36) weeks. A total of 53.8% (no = 78) of the patients had live birth, 51.7% (no = 70) had at least one abortion in the first 20 weeks, and 13.1% (no = 19) had at least one stillbirth after 20 weeks. The rate of patients' increased numbers of dialysis sessions during pregnancy was 71.7%. The abortion rate was 22.4% in those with increased HD sessions, whereas 79.3% in those not increased HD sessions (p < 0.001). Live birth frequency was 67.2% in the increased HD sessions group and 3.4% in those who did not differ in HD sessions (p < 0.001). Conclusion: For the first time, we reported pregnancy outcomes in HD female patients, covering all regions of Turkey. It has been observed that; increasing the number of HD sessions in dialysis patients will decrease fetal and maternal complications and increase live birth rates