63 research outputs found

    Family Treated as a Value for a Child Brought up in an Educational Care Centre (The Orphanage). Case of Poland

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    Family life concerns subjective and individual moments which are always unique and constitute a part of one s life Therefore it is more difficult to establish the value that is attributed to the notion of family by people in general In order to define the value of specific existing family environment the quality of life of the constituents of such an environment are taken into account Experience and the level of satisfying individual needs have a great impact on the quality of one s family life If a family finds itself in a deep trouble and is unable to tackle it then its life quality is impoverished in a significant way The consequences of disfunctioning of a family as well as the inability to perform the tasks that a family is expected to fulfil are severe These ramifications have a great impact on a child s life and the worst case scenario happens if the child is separated from its family On the basis of the interview with a person who grew up in the orphanage it can be concluded that despite the fact that one may have bad memories about their family and he or she may think low of it family is still ideologically valuable for the

    Xenoestrogens diethylstilbestrol and zearalenone negatively influence pubertal rat's testis.

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    The aim of this study was to assess the impact of xenoestrogens: diethylstilbestrol (DES) and zearalenone (ZEA) on rat's pubertal testis and to compare it with the effect of natural estrogen - 17beta-estradiol (E). Male Wistar rats were daily, subcutaneously injected at 5th-15th postnatal days (p.d.) with E (1.25 or 12.5 mug) or DES (1.25 or 12.5 mug) or ZEA (4 or 40 mug) or vehicle. At 16th p.d. testes were dissected, weighted, and paraffin embedded. Following parameters were assessed: diameter and length of seminiferous tubule, numbers of spermatogonia A+intermediate+B (A/In/B), preleptotene spermatocytes (PL), leptotene+zygotene+pachytene spermatocytes (L/Z/PA) and Sertoli cells per testis. Testes weight, seminiferous tubule diameter and length were decreased by both doses of E, DES and ZEA. DES effect was the strongest, but its influence on testis weight and seminiferous tubule length, on the contrary to E and ZEA, was not dose-dependent. Similarly, DES in both doses had the most severe negative impact on the number of germ and Sertoli cells. The negative influence of E on germ cells was less pronounced. The negative effect of ZEA was seen only after administration of the higher dose on spermatogonia number, while DES and E decreased A/In/B number more evidently. Sertoli cell number were decreased after both doses of E. ZEA40 decreased Sertoli cell number while ZEA4 had no effect. Conclusion: exposure of prepubertal male rat to DES has the strongest detrimental effect on the developing testis in comparison to E and ZEA. Both, E and DES, decreased number of germ and Sertoli cells, diminished seminiferous tubule diameter, length and testis weight. ZEA had much more weaker effect than the potent estrogens

    Experience with the use of Stimol® in Acute Pyelonephritis in Children

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    The results of the clinical use of Stimol® in the comprehensive treatment of acute pyelonephritis in 58 children. It is established that the inclusion of metabolism corrector Stimol® in complex of medical treatment of patients with acute pyelonephritis contributes to the stabilization of the clinical condition of patients, reducing symptoms of intoxication (improved appetite, reduced general malaise, normalization of temperature). The findings show the feasibility and clinical efficacy of Stimol® administration, which can be regarded as one of the promising methods of detoxification therapy

    Experience with the use of Stimol in Acute Pyelonephritis in Children

    No full text
    The results of the clinical use of Stimol® in the comprehensive treatment of acute pyelonephritis in 58 children. It is established that the inclusion of metabolism corrector Stimol® in complex of medical treatment of patients with acute pyelonephritis contributes to the stabilization of the clinical condition of patients, reducing symptoms of intoxication (improved appetite, reduced general malaise, normalization of temperature). The findings show the feasibility and clinical efficacy of Stimol® administration, which can be regarded as one of the promising methods of detoxification therapy
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