358 research outputs found
The catalytic removal of ammonia and nitrogen oxides from spacecabin atmospheres
Investigations were made on methods for the removal of ammonia and to a lesser extent nitrogen oxides in low concentrations from air. The catalytic oxidation of ammonia was studied over a temperature range of 250 F to 600 F and a concentration range 20 ppm to 500 ppm. Of the catalysts studied, 0.5 percent ruthenium supported on alumina was found to be superior. This material is active at temperatures as low as 250 F and was found to produce much less nitrous oxide than the other two active catalysts, platinum on alumina and Hopcalite. A quantitative design model was developed which will permit the performance of an oxidizer to be calculated. The ruthenium was found to be relatively insensitive to low concentrations of water and to oxygen concentration between 21 percent and 100 percent. Hydrogen sulfide was found to be a poison when injected in relatively large quantities. The adsorption of ammonia by copper sulfate treated silica gel was investigated at temperatures of 72 F and 100 F. A quantitative model was developed for predicting adsorption bed behavior
Removal of acid gases and oxides of nitrogen from space cabin atmospheres
Removal of acid gases and oxides of nitrogen from spacecraft cabin atmospheres at ambient temperature
Observation of anomalous spin-state segregation in a trapped ultra-cold vapor
We observe counter-intuitive spin segregation in an inhomogeneous sample of
ultra-cold, non-condensed Rubidium atoms in a magnetic trap. We use spatially
selective microwave spectroscopy to verify a model that accounts for the
differential forces on two internal spin states. In any simple understanding of
the cloud dynamics, the forces are far too small to account for the dramatic
transient spin polarizations observed. The underlying mechanism remains to be
elucidated.Comment: 5 pages, 3 figure
Internal state conversion in ultracold gases
We consider an ultracold gas of (non-condensed) bosons or fermions with two
internal states, and study the effect of a gradient of the transition frequency
between these states. When a RF pulse is applied to the sample,
exchange effects during collisions transfer the atoms into internal states
which depend on the direction of their velocity. This results, after a short
time, in a spatial separation between the two states. A kinetic equation is
solved analytically and numerically; the results agree well with the recent
observations of Lewandowski et al.Comment: Accepted version, to appear in PR
Discovery of a New WZ Sagittae Type Cataclysmic Variable in the Kepler/K2 Data
We identify a new, bright transient in the Kepler/K2 Campaign 11 field. Its
light curve rises over seven magnitudes in a day and then declines three
magnitudes over a month before quickly fading another two magnitudes. The
transient was still detectable at the end of the campaign. The light curve is
consistent with a WZ~Sge type dwarf nova outburst. Early superhumps with a
period of 82 minutes are seen in the first 10 days and suggest that this is the
orbital period of the binary which is typical for the WZ~Sge class. Strong
superhump oscillations develop ten days after peak brightness with periods
ranging between 83 and 84 minutes. At 25 days after the peak brightness a bump
in the light curve appears to signal a subtle rebrightening phase implying that
this was an unusual type-A outburst. This is the only WZ~Sge type system
observed by Kepler/K2 during an outburst. The early rise of this outburst is
well-fit with a broken power law. In first 10 hours the system brightened
linearly and then transitioned to a steep rise with a power law index of 4.8.
Looking at archival Kepler/K2 data and new TESS observations, a linear rise in
the first several hours at the initiation of a superoutburst appears to be
common in SU~UMa stars.Comment: 11 pages, 14 figures, 2 tables, accepted to appear in the Monthly
Notices of the Royal Astronomical Societ
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High performance electromagnetic railgun launcher
A railgun operates at high pressure (up to 350 MPa) without structural damage and is readily disassembled for inspection, maintenance and component testing. A rail assembly is pressed into a hoop-wound epoxy fiberglass containment tube and clamped within a steel compression frame. The geometry of the rail assembly permits rail movement without insulator intrusion and achieves bore sealing during rail movement at maximum pressure. The rail assembly also has replaceable insulator inserts which are isolated from rail re-bound shock. Fused quartz insulator inserts provide the best results. A flash tube is provided at the gun muzzle to suppress precursor discharge and commutate precursor current back to the armature. To realize increased velocity without sacrificing in-bore projectile stability, a cut-corner projectile is used having a L/D ratio as small as 0.65 which reduces the mass by about 11%.Board of Regents, University of Texas Syste
Optical Confinement of a Bose-Einstein Condensate
Bose-Einstein condensates of sodium atoms have been confined in an optical
dipole trap using a single focused infrared laser beam. This eliminates the
restrictions of magnetic traps for further studies of atom lasers and
Bose-Einstein condensates. More than five million condensed atoms were
transferred into the optical trap. Densities of up to of Bose condensed atoms were obtained, allowing for a measurement of
the three-body decay rate constant for sodium condensates as . At lower densities, the observed 1/e
lifetime was more than 10 sec. Simultaneous confinement of Bose-Einstein
condensates in several hyperfine states was demonstrated.Comment: 5 pages, 4 figure
Transcriptomic dissection of Bradyrhizobium sp. strain ORS285 in symbiosis with Aeschynomene spp. inducing different bacteroid morphotypes with contrasted symbiotic efficiency
To circumvent the paucity of nitrogen sources in the soil legume plants establish a symbiotic interaction with nitrogen-fixing soil bacteria called rhizobia. During symbiosis, the plants form root organs called nodules, where bacteria are housed intracellularly and become active nitrogen fixers known as bacteroids. Depending on their host plant, bacteroids can adopt different morphotypes, being either unmodified (U), elongated (E) or spherical (S). E- and S-type bacteroids undergo a terminal differentiation leading to irreversible morphological changes and DNA endoreduplication. Previous studies suggest that differentiated bacteroids display an increased symbiotic efficiency (E>U and S>U). In this study, we used a combination of Aeschynomene species inducing E- or S-type bacteroids in symbiosis with Bradyrhizobium sp. ORS285 to show that S-type bacteroids present a better symbiotic efficiency than E-type bacteroids. We performed a transcriptomic analysis on E- and S-type bacteroids formed by Aeschynomene afraspera and Aeschynomene indica nodules and identified the bacterial functions activated in bacteroids and specific to each bacteroid type. Extending the expression analysis in E- and S-type bacteroids in other Aeschynomene species by qRT-PCR on selected genes from the transcriptome analysis narrowed down the set of bacteroid morphotype-specific genes. Functional analysis of a selected subset of 31 bacteroid-induced or morphotype-specific genes revealed no symbiotic phenotypes in the mutants. This highlights the robustness of the symbiotic program but could also indicate that the bacterial response to the plant environment is partially anticipatory or even maladaptive. Our analysis confirms the correlation between differentiation and efficiency of the bacteroids and provides a framework for the identification of bacterial functions that affect the efficiency of bacteroids. This article is protected by copyright. All rights reserved
Porphyromonas gingivalis peptidylarginine deiminase, a key contributor in the pathogenesis of experimental periodontal disease and experimental arthritis
OBJECTIVES: To investigate the suggested role of Porphyromonas gingivalis peptidylarginine deiminase (PAD) in the relationship between the aetiology of periodontal disease and experimentally induced arthritis and the possible association between these two conditions. METHODS: A genetically modified PAD-deficient strain of P. gingivalis W50 was produced. The effect of this strain, compared to the wild type, in an established murine model for experimental periodontitis and experimental arthritis was assessed. Experimental periodontitis was induced following oral inoculation with the PAD-deficient and wild type strains of P. gingivalis. Experimental arthritis was induced via the collagen antibody induction process and was monitored by assessment of paw swelling and micro-CT analysis of the radio-carpal joints. Experimental periodontitis was monitored by micro CT scans of the mandible and histological assessment of the periodontal tissues around the mandibular molars. Serum levels of anti-citrullinated protein antibodies (ACPA) and P. gingivalis were assessed by ELISA. RESULTS: The development of experimental periodontitis was significantly reduced in the presence of the PAD-deficient P. gingivalis strain. When experimental arthritis was induced in the presence of the PAD-deficient strain there was less paw swelling, less erosive bone damage to the joints and reduced serum ACPA levels when compared to the wild type P. gingivalis inoculated group. CONCLUSION: This study has demonstrated that a PAD-deficient strain of P. gingivalis was associated with significantly reduced periodontal inflammation. In addition the extent of experimental arthritis was significantly reduced in animals exposed to prior induction of periodontal disease through oral inoculation of the PAD-deficient strain versus the wild type. This adds further evidence to the potential role for P. gingivalis and its PAD in the pathogenesis of periodontitis and exacerbation of arthritis. Further studies are now needed to elucidate the mechanisms which drive these processes.Neville Gully, Richard Bright, Victor Marino, Ceilidh Marchant, Melissa Cantley, David Haynes, Catherine Butler, Stuart Dashper, Eric Reynolds, Mark Bartol
Human γδ T cells recognize CD1b by two distinct mechanisms
γδ T cells form an abundant part of the human cellular immune system, where they respond to tissue damage, infection, and cancer. The spectrum of known molecular targets recognized by Vδ1-expressing γδ T cells is becoming increasingly diverse. Here we describe human γδ T cells that recognize CD1b, a lipid antigen-presenting molecule, which is inducibly expressed on monocytes and dendritic cells. Using CD1b tetramers to study multiple donors, we found that many CD1b-specific γδ T cells use Vδ1. Despite their common use of Vδ1, three CD1b-specific γδ T cell receptors (TCRs) showed clear differences in the surface of CD1b recognized, the requirement for lipid antigens, and corecognition of butryophilin-like proteins. Several Vγ segments were present among the CD1b-specific TCRs, but chain swap experiments demonstrated that CD1b specificity was mediated by the Vδ1 chain. One of the CD1b-specific Vδ1+ TCRs paired with Vγ4 and shows dual reactivity to CD1b and butyrophilin-like proteins. αβ TCRs typically recognize the peptide display platform of MHC proteins. In contrast, our results demonstrate the use of rearranged receptors to mediate diverse modes of recognition across the surface of CD1b in ways that do and do not require carried lipids
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