242 research outputs found

    Associations between Maternal Technology Use, Perceptions of Infant Temperament, and Indicators of Mother-to-Infant Attachment Quality

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    Background: Previous research suggests parents\u27 use of technological devices, such as TV and mobile devices, within family contexts may decrease the quality of parent-child interactions. During early infancy, mothers report engaging with technological devices during infant feeding and care interactions, however, few studies have explored potential associations between maternal technology use and the quality of mother-to-infant attachment. Aim: To examine associations between maternal technology use during mother-infant interactions and indicators of mother-to-infant attachment during early infancy. Study design: Cross-sectional survey. Methods: Mothers (n = 332) of infants aged 2 to 6 months were recruited via MTurk, a crowdsourcing platform, to participate in an online survey. Participants responded to a series of validated questionnaires that assessed maternal technology use during mother-infant interactions (Maternal Distraction Questionnaire), infant temperament (Infant Behavior Questionnaire-Revised Very Short Form), and indicators of mother-to-infant attachment, including quality of attachment, absence of hostility toward motherhood, and pleasure in mother-infant interactions (Maternal Postnatal Attachment Questionnaire). Results: Greater technology use during mother-infant interactions was significantly associated with greater infant negative affectivity (β = 0.26, p \u3c .0001). Greater technology use was also significantly associated with lower mother-to-infant attachment quality (β = −0.21, p = .0001), and greater hostility toward motherhood (β = −0.39, p \u3c .0001). Associations between technology use and indicators of mother-to-infant attachment were not mediated by infant negative affectivity. Conclusions: Maternal technology use was associated with greater perceptions of infant negative affectivity and poorer mother-to-infant attachment quality; further research is needed to understand mechanisms underlying these associations

    La Venezuela postrentista y la economía del conocimiento. Breves notas para contribuir a colocar el tema en el radar nacional.

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    Durante los últimos años el valor del barril de petróleo ha bajado sustancialmente. Sin embargo,los entendidos afirman que la presente crisis muestra esta vez otros ribetes, pues no se tratasólo de la las modificaciones más o menos típicas en el funcionamiento del mercado de loshidrocarburos, sino que comienza a anunciar también la transición hacia un modelo degeneración de energías no fósiles, como respuesta a los serios desacomodos ambientales.Vivimos períodos en buena medida definidos por un conjunto de nuevas tecnologías, cuyosefectos también llegan hasta orillas venezolanas, trayéndonos oportunidades, problemas ydesafíos que nos remiten a la urgencia de superar el agotamiento del modelo rentista, a travésde la Economía del Conocimiento, desarrollada conforme a los códigos que gobiernan el sigloXXI

    Ciência, tecnología e inovação na relação universidade-empresa-estado (UEE) em Colômbia

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    This reflection article is intended to consider the framework of bonding for the promotion of science, the incubation of technology training and stimulation of innovation by the University relationship, business and State UEE. Although, at first sight, there are elements that lead to define the bets placed on these topics by the participants in such triad, the reality is that so far not said anything consistent as to the determination of the road map that will guide this relationship for these fields. UEE relationship is the scene of negotiations in which the parties have decided to share their concerns on proposals of interest of the parties, identified in the aforementioned topics. The link, has allowed expanding the expectations created in the maturation of the (CT&I).El artículo tiene el propósito de considerar el marco de vinculación para el fomento de la ciencia, la incubación de formación tecnológica y la estimulación de la innovación en la relación Universidad, Empresa y Estado, UEE. Aunque a primera vista existen elementos que conducen a definir las apuestas hechas en dichos tópicos por los agentes participantes en dicha triada, la realidad es que hasta ahora no se ha dicho nada congruente en cuanto a la determinación del derrotero que guiará dicha relación en pro de dichos campos. La relación UEE es el escenario de negociación en el que las partes han decidido compartir sus inquietudes sobre propuestas de su interés en los tópicos mencionados. El vínculo ha permitido ampliar las expectativas creadas en la maduración de la (CT&I).O artigo tem o propósito de considerar o marco de vinculação para a promoção da ciência, a incubação da formação tecnológica e estimulo da inovação na relação Universidade, Empresa e Estado, UEE. Embora a primera vista existam elementos que conduzem a definição das apostas feitas pelos participantes, a realidade é que até agora não se falou nada consistente quanto a determinação do curso que vai orientar o relacionamento em favor desses campos. A relação UEE é o cenário de negociação em que as partes decidiram compartilhar suas preucupações sobre propostas de seu interesse nos temas mencionados. O vínculo permitiu ampliar as expectativas criadas na maduração da (CT&I)

    Inhibición de la formación de subproductos en la glicosilación avanzada por derivados de estilbeno y fenantreno de Prosthechea michuacana, in vitro e in vivo

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    En un estudio anterior, aislamos del extracto clorofórmico de los bulbos de la orquídea Prosthechea michuacana, tres compuestos antioxidantes: los  estilbenos α-α´-dihidro, 3´,5´,2-trimethoxi-3-hidroxi-4-acetil-4´-isopentenil-stilbeno, 5-[2-(3-hydroxy-5-methoxyphenyl)ethyl]-2-methoxyphenol (gigantol) y    el fenantreno 4,6,7-trihidroxi -2-methoxi-8-(metilbut-2-enilfenantren-1-1´-4´,6´,7´-trihidroxi-2´-metoxi-8´-(metilbut-2´-enil)-fenantreno. Continuando con el  estudio, investigamos la capacidad de estos compuestos para inhibir la glicación avanzada in vitro. La seroalbúmina bovina se glicosiló en presencia de  glucosa o metilglioxal. La reacción de Amadori se determinó con lisozima glicosilada previamente tratada con ribosa. También se evaluó la función renal  mediante la formación de la glicación avanzada y la inhibición de AGEs en el ensayo sobre el colágeno del tendón de la cola en ratones con diabetes inducida  con estreptozotocina. También determinamos el efecto de los compuestos aislados sobre LDL y hemoglobin. Los compuestos pueden inhibir eficazmente la  formación de AGE atrapando el metilglioxal reactivo y muestran potente actividad anti Amadorin. También mostraron una actividad inhibitoria significativa  en la formación de la hemoglobina glucosilada, GHB y HbA1c. Mostraron un efecto protector renal y una reducción en el colágeno glicosiladó del tendón de  la cola. También estos compuestos son potentes agentes para la protección de LDL frente la oxidación y la glicación. En base a los resultados obtenidos se  concluye que los compuestos aislados son potentes agentes antiglicación, que pueden ser de gran valor en la prevención de la patogénesis de la diabetes  asociada a la glicación

    The Commissioning Instrument for the Dark Energy Spectroscopic Instrument

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    We describe the design of the Commissioning Instrument for the Dark Energy Spectroscopic Instrument (DESI). DESI will obtain spectra over a 3 degree field of view using the 4-meter Mayall Telescope at Kitt Peak, AZ. In order to achieve the required image quality over this field of view, a new optical corrector is being installed at the Mayall Telescope. The Commissioning Instrument is designed to characterize the image quality of the new optical system. The Commissioning Instrument has five commercial cameras; one at the center of the focal surface and four near the periphery of the field and at the cardinal directions. There are also 22 illuminated fiducials, distributed throughout the focal surface, that will be used to test the system that will map between the DESI fiber positioners and celestial coordinates. We describe how the commissioning instrument will perform commissioning tasks for the DESI project and thereby eliminate risks.Comment: Presented at SPIE June 2018; Proc. SPIE 10702, Ground-based and Airborne Instrumentation for Astronomy VII, 107028

    Position statement and updated international guideline for safe and effective whole-body electromyostimulation training-the need for common sense in WB-EMS application

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    Whole-Body Electromyostimulation (WB-EMS) is a training technology that enables simultaneous stimulation of all the main muscle groups with a specific impulse intensity for each electrode. The corresponding time-efficiency and joint-friendliness of WB-EMS may be particularly attractive for people unable or unmotivated to conduct (intense) conventional training protocols. However, due to the enormous metabolic and musculoskeletal impact of WB-EMS, particular attention must be paid to the application of this technology. In the past, several scientific and newspaper articles reported severe adverse effects of WB-EMS. To increase the safety of commercial non-medical WB-EMS application, recommendations "for safe and effective whole-body electromyostimulation" were launched in 2016. However, new developments and trends require an update of these recommendations to incorporate more international expertise with demonstrated experience in the application of WB-EMS. The new version of these consensus-based recommendations has been structured into 1) "general aspects of WB-EMS", 2) "preparation for training", recommendations for the 3) "WB-EMS application" itself and 4) "safety aspects during and after training". Key topics particularly addressed are 1) consistent and close supervision of WB-EMS application, 2) mandatory qualification of WB-EMS trainers, 3) anamnesis and corresponding consideration of contraindications prior to WB-EMS, 4) the participant's proper preparation for the session, 5) careful preparation of the WB-EMS novice, 6) appropriate regeneration periods between WB-EMS sessions and 7) continuous interaction between trainer and participant at a close physical distance. In summary, we are convinced that the present guideline will contribute to greater safety and effectiveness in the area of non-medical commercial WB-EMS application

    A translational approach to assess the metabolomic impact of stabilized gold nanoparticles by NMR spectroscopy

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    [EN] Gold nanoparticles have high potential in the biomedical area, especially in disease diagnosis and treatment. The application of these nanoparticles requires the presence of stabilizers to avoid their agglomeration. Nowadays, there is a lack of reliable methods for characterising the effect of stabilised nanoparticles on biological systems. To this end, in this study, we apply an experimental approach based on nuclear magnetic resonance spectroscopy to study the effect of gold nanoparticles, stabilised with cerium oxide or chitosan, on a human cancer cell model. The results showed that both systems have a significant effect, even at non-toxic levels, on the cellular antioxidant system. However, although particles functionalised with chitosan exerted a strong effect on the aerobic respiration, nanoparticles stabilised with cerium oxide had a higher impact on the mechanisms associated with anaerobic energy production. Therefore, even though both systems contained similar gold nanoparticles, the presence of different stabilizers strongly influenced their mode of action and potential applications in biomedicine.This work was supported by the Carlos III Health Institute, the European Regional Development Fund (PI16/02064 and CP13/00252) and the Spanish Ministerio de Economia y Competitividad (SAF2014-53977-R, SAF2017-89229-R and RD12/0036/0025). In addition, JRH is a recipient of a contract from the Ministry of Health of the Carlos III Health Institute.Herance, JR.; García Gómez, H.; Guitierrez Carcedo, P.; Navalón Oltra, S.; Pineda-Lucena, A.; Palomino-Schätzlein, M. (2019). A translational approach to assess the metabolomic impact of stabilized gold nanoparticles by NMR spectroscopy. The Analyst. 144(4):1265-1274. https://doi.org/10.1039/c8an01827hS126512741444Shi, J., Kantoff, P. W., Wooster, R., & Farokhzad, O. C. (2016). Cancer nanomedicine: progress, challenges and opportunities. 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    Campus Mysteries: Serious Walking Around

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    The Campus Mysteries project developed an augmented reality game platform called fAR-Play and a learning game called Campus Mysteries with the platform. This paper reports on the development of the platform, the development of the game, and a assessment of the playability of the game. We conclude that augmented reality games are a viable model for learning and that the process of development is itself the site of learning
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