620 research outputs found
A one dimensional model for the prediction of extraction yields in a two phases modified twin-screw extruder
Solid/liquid extraction is performed on raw plant substrate with a modified twin-screw extruder (TSE) used as a thermo-mecanochemical reactor. Visual observations and experimental residence time distributions (RTD) are used to develop a solid transport model based on classical chemical engineering method. Modeled and experimental residence times are compared. The transport model is then coupled with a reactive extraction model in order to predict extraction yields
Two phase residence time distribution in a modified twin screw extruder
Biomass fractionation is performed with a modified Clextral twin-screw extruder used as a thermo-mechano-chemical reactor. This new process is firstly analyzed. Visual observations, residence time distributions, and global mass balances are used to obtain information about the process phenomena and their coupling. Residence time distributions (RTD) classical models are adopted to represent the experimental plots. The influence of continuous and discrete process parameters upon the RTD of the solid and liquid phases is analyzed
Dipyridamole plus aspirin versus aspirin alone in the secondary prevention after TIA or stroke: a meta-analysis by risk
Objectives: Our aim was to study the effect of combination therapy with aspirin and dipyridamole (A+D) over aspirin alone (ASA) in secondary prevention after transient
ischemic attack or minor stroke of presumed arterial origin and to perform subgroup analyses to identify patients that might benefit most from secondary prevention with A+D.
Data sources: The previously published meta-analysis of individual patient data was updated with data from ESPRIT (N=2,739); trials without data on the comparison of A+D versus ASA were excluded.
Review methods: A meta-analysis was performed using Cox regression, including several subgroup analyses and following baseline risk stratification.
Results: A total of 7,612 patients (5 trials) were included in the analyses, 3,800 allocated to A+D and 3,812 to ASA alone. The trial-adjusted hazard ratio for the composite event of vascular death, non-fatal myocardial infarction and non-fatal stroke was 0.82 (95% confidence interval 0.72-0.92). Hazard ratios did not differ in subgroup analyses based on age, sex, qualifying event, hypertension, diabetes, previous stroke, ischemic heart disease,
aspirin dose, type of vessel disease and dipyridamole formulation, nor across baseline risk strata as assessed with two different risk scores. A+D were also more effective than ASA alone in preventing recurrent stroke, HR 0.78 (95% CI 0.68 â 0.90).
Conclusion: The combination of aspirin and dipyridamole is more effective than aspirin alone in patients with TIA or ischemic stroke of presumed arterial origin in the secondary
prevention of stroke and other vascular events. This superiority was found in all subgroups and was independent of baseline risk. ---------------------------7dc3521430776
Content-Disposition: form-data; name="c14_creators_1_name_family"
Halke
Exhumation of the Sierra de Cameros (Iberian Range, Spain): constraints from low-temperature thermochronology
We present new fission-track and (UâTh)/He data from apatite and zircon in order to
reconstruct the exhumation of the Sierra de Cameros, in the northwestern part of Iberian Range,
Spain. Zircon fission-track ages from samples from the depocentre of the basin were reset
during the metamorphic peak at approximately 100 Ma. Detrital apatites from the uppermost sediments
retain fission-track age information that is older than the sediment deposition age, indicating
that these rocks have not exceeded 110 8C. Apatites from deeper in the stratigraphic sequence of
the central part of the basin have fission-track ages of around 40 Ma, significantly younger than
the stratigraphic age, recording the time of cooling after peak metamorphic conditions. Apatite
(UâTh)/He ages in samples from these sediments are 31â40 Ma and record the last period of
cooling during Alpine compression. The modelled thermal history derived from the uppermost
sediments indicates that the thermal pulse associated with peak metamorphism was rapid, and
that the region has cooled continuously to the present. The estimated palaeogeothermal gradient
is around 86 8C km21 and supports a tectonic model with a thick sedimentary fill (c. 8 km) and
explains the origin of the low-grade metamorphism observed in the oldest sediments
Assessment by accelerometer of sedentarity and of adherence to physical activity recommendations after cardiac rehabilitation program
Recommended from our members
Operationalising and measuring language dominance
The paper offers a new way to measure language ability in bilinguals, based on measures of lexical richness. The validity of proposed approach is tested in a variety of ways
Decay and Continuity of Boltzmann Equation in Bounded Domains
Boundaries occur naturally in kinetic equations and boundary effects are
crucial for dynamics of dilute gases governed by the Boltzmann equation. We
develop a mathematical theory to study the time decay and continuity of
Boltzmann solutions for four basic types of boundary conditions: inflow,
bounce-back reflection, specular reflection, and diffuse reflection. We
establish exponential decay in norm for hard potentials for
general classes of smooth domains near an absolute Maxwellian. Moreover, in
convex domains, we also establish continuity for these Boltzmann solutions away
from the grazing set of the velocity at the boundary. Our contribution is based
on a new decay theory and its interplay with delicate
decay analysis for the linearized Boltzmann equation, in the presence of many
repeated interactions with the boundary.Comment: 89 pages
Integrate and Fire Neural Networks, Piecewise Contractive Maps and Limit Cycles
We study the global dynamics of integrate and fire neural networks composed
of an arbitrary number of identical neurons interacting by inhibition and
excitation. We prove that if the interactions are strong enough, then the
support of the stable asymptotic dynamics consists of limit cycles. We also
find sufficient conditions for the synchronization of networks containing
excitatory neurons. The proofs are based on the analysis of the equivalent
dynamics of a piecewise continuous Poincar\'e map associated to the system. We
show that for strong interactions the Poincar\'e map is piecewise contractive.
Using this contraction property, we prove that there exist a countable number
of limit cycles attracting all the orbits dropping into the stable subset of
the phase space. This result applies not only to the Poincar\'e map under
study, but also to a wide class of general n-dimensional piecewise contractive
maps.Comment: 46 pages. In this version we added many comments suggested by the
referees all along the paper, we changed the introduction and the section
containing the conclusions. The final version will appear in Journal of
Mathematical Biology of SPRINGER and will be available at
http://www.springerlink.com/content/0303-681
Evidence for surface uplift of the Atlas Mountains and the surrounding peripheral plateaux: Combining apatite fission-track results and geomorphic indicators in the Western Moroccan Meseta (coastal Variscan Paleozoic basement)
This work represents an initial attempt to link the evolution of the topography in relation to the general tectonic framework of western Morocco. For this purpose, in a section of the Western Moroccan Meseta different tools are combined in order to attain the general objective. Apatite fission-track (AFT) data of granitic rocks of the RabatâKhenifra area give ages around 200 Ma with track length distributions which are compatible with the thermal models already established for the area. An inverse correlation between AFT ages and elevation is observed which is compatible with previous models indicating northward tilting of the whole Western Moroccan Meseta which is younger than 20â25 Ma. In order to test this possibility a detailed analysis of the topography at different scales in the Western Moroccan Meseta has been performed. Results indicate that two open folds with different amplitudes are recognized and that the one with wider wavelength could correspond to a lithospheric fold as previously stated by other authors on the basis of independent geological arguments. The northward tilting proposed based on the AFT data agrees with the results obtained in the analysis of the topography which reinforces the presence of a very open fold with a wavelength of 200â300 km in the north-western limb of the Western Moroccan Meseta
On Hilberg's Law and Its Links with Guiraud's Law
Hilberg (1990) supposed that finite-order excess entropy of a random human
text is proportional to the square root of the text length. Assuming that
Hilberg's hypothesis is true, we derive Guiraud's law, which states that the
number of word types in a text is greater than proportional to the square root
of the text length. Our derivation is based on some mathematical conjecture in
coding theory and on several experiments suggesting that words can be defined
approximately as the nonterminals of the shortest context-free grammar for the
text. Such operational definition of words can be applied even to texts
deprived of spaces, which do not allow for Mandelbrot's ``intermittent
silence'' explanation of Zipf's and Guiraud's laws. In contrast to
Mandelbrot's, our model assumes some probabilistic long-memory effects in human
narration and might be capable of explaining Menzerath's law.Comment: To appear in Journal of Quantitative Linguistic
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