Searching for low mass objects around nearby dMe radio stars

Nearby M-dwarfs are best suited for searches of low mass companions. VLBI phase-referencing observations with sensitive telescopes are able to detect radio star flux-densities of tenths of mJy as well as to position the star on the sky with submilliarcsecond precision. We have initiated a long-term observational program, using EVN telescopes in combination with NASA DSN dishes, to revisit the kinematics of nearby, single M dwarfs. The precision of the astrometry allows us to search for possible companions with masses down to 1 Jupiter mass. In this contribution we report preliminary results of the first observation epochs, in which we could detect some of the radio stars included in our program.Comment: Proceedings of the 6th European VLBI Network Symposium, Ros E., Porcas R.W., Lobanov A.P., & Zensus J.A. (eds.), MPIfR, Bonn, Germany, p. 255-258 (2002). 4 pages, 3 figures, needs evn2002.cl

Genetical stability and osteogenic ability of mesenchimal stem cells on demineralized bone matrices

Journal of Osseointegration Volume 7, Issue 1, 1 March 2015, Pages 2-7 Open Access Genetical stability and osteogenic ability of mesenchimal stem cells on demineralized bone matrices (Article) Pozzuoli, A.a, Gardin, C.b, Aldegheri, R.a, Bressan, E.c, Isola, M.d, Calvo-Guirado, J.L.e, Biz, C.a, Arrigoni, P.a, Feroni, L.b, Zavan, B.b a Department of Surgical,Oncological and Gastroenterological Sciences, University of Padua, Padua, Italy b Department of Biomedical Sciences, University of Padua, Padua, Italy c Department of Neurosciences, University of Padua, Padua, Italy d Department of Animal Medicine, Production and Health (MAPS), Italy e Department of General Dentistry, Faculty of Medicine and Dentistry, University of Murcia, Murcia, Spain Hide additional affiliations View references (44) Abstract Aim: Tissue engineering is a rapidly expanding field with regard to the use of biomaterials and stem cells in the orthopedic surgery. Many experimental studies have been done to understand the best characteristics of cells, materials and laboratory methods for safe clinical applications. The aim of this study was to compare the ability of 2 different human demineralized bone matrices (DBMs), the one enriched and the other not enriched with hyaluronic acid, to stimulate in vitro the proliferation and the osteogenic differentiation of human adipose-derived stem cells (ADSCs) seeded onto an osteoconductive scaffold. Materials and Methods: ADSCs were isolated, by enzymatic digestion, from abdominal adipose tissue of 5 patients undergoing cosmetic lipoaspiration surgery. ADSCs were then seeded onto a 3D scaffold in the presence of the two different osteoinductive matrices of human demineralized bone and evaluated for proliferation and osteogenic differentiation. The safety of the methods was verified using array-Comparative Genomic Hybridization (array-CGH). Results: ADSCs were able to differentiate in osteogenic sense. Both DBMs showed the ability to induce osteogenic differentiation of the cells. Conclusion: array-CGH showed no changes at genome level, thus confirming the safety of materials and method

Profilometry for the measurement of 3-D object shapes based on regularized filters

Regularized filters RFs. are used in profilometry for the measurement of three-dimensional object shapes. A linear grating pattern projected onto an object is phase-modulated by the 3-D shape. Phase information of the pattern is obtained by a demodulation process using RFs based on Bayesian estimation theory with Markov Random Fields MRFs. as prior models. The technique is fully processed in the space domain and applied in the 2-D case to provide a better separation of the height information from noise. As shown herein, the technique is not so sensitive to the singularities in the pattern image as with common filters used in the spatial synchronous detection. The technique and experimental results of real surface profiles are presented. q1999 Published by Elsevier Science B.V. All rights reserved

SARS-CoV-2, Zika viruses and mycoplasma:Structure, pathogenesis and some treatment options in these emerging viral and bacterial infectious diseases

The molecular evolution of life on earth along with changing environmental, conditions has rendered mankind susceptible to endemic and pandemic emerging infectious diseases. The effects of certain systemic viral and bacterial infections on morbidity and mortality are considered as examples of recent emerging infections. Here we will focus on three examples of infections that are important in pregnancy and early childhood: SARS-CoV-2 virus, Zika virus, and Mycoplasma species. The basic structural characteristics of these infectious agents will be examined, along with their general pathogenic mechanisms. Coronavirus infections, such as caused by the SARS-CoV-2 virus, likely evolved from zoonotic bat viruses to infect humans and cause a pandemic that has been the biggest challenge for humanity since the Spanish Flu pandemic of the early 20th century. In contrast, Zika Virus infections represent an expanding infectious threat in the context of global climate change. The relationship of these infections to pregnancy, the vertical transmission and neurological sequels make these viruses highly relevant to the topics of this special issue. Finally, mycoplasmal infections have been present before mankind evolved, but they were rarely identified as human pathogens until recently, and they are now recognized as important coinfections that are able to modify the course and prognosis of various infectious diseases and other chronic illnesses. The infectious processes caused by these intracellular microorganisms are examined as well as some general aspects of their pathogeneses, clinical presentations, and diagnoses. We will finally consider examples of treatments that have been used to reduce morbidity and mortality of these infections and discuss briefly the current status of vaccines, in particular, against the SARS-CoV-2 virus. It is important to understand some of the basic features of these emerging infectious diseases and the pathogens involved in order to better appreciate the contributions of this special issue on how infectious diseases can affect human pregnancy, fetuses and neonates

Improved age constraints for the AB Dor quadruple system - The binary nature of AB Dor B

We present resolved NACO photometry of the close binary AB Dor B in H- and Ks-band. AB Dor B is itself known to be a wide binary companion to AB Dor A, which in turn has a very low-mass close companion named AB Dor C. These four known components make up the young and dynamically interesting system AB Dor, which will likely become a benchmark system for calibrating theoretical pre-main sequence evolutionary mass tracks for low-mass stars. However, for this purpose the actual age has to be known, and this subject has been a matter of discussion in the recent scientific literature. We compare our resolved photometry of AB Dor Ba and Bb with theoretical and empirical isochrones in order to constrain the age of the system. This leads to an age estimate of about 50 to 100 Myr. We discuss the implications of such an age range for the case of AB Dor C, and compare with other results in the literature.Comment: 7 pages, 6 figures, accepted for publication in A&

Space-VLBI phase-reference mapping and astrometry

We present 5 GHz space-VLBI observations of the quasar pair B1342+662/B1342+663 that demonstrate the feasibility of phase-reference techniques using an antenna in space. The space-based data were taken by the satellite HALCA, of the space-VLBI mission VSOP. From residual (referenced) phases we derive an upper bound of 10 meters to the uncertainty of the spacecraft orbit reconstruction. An analysis of the phase-reference maps of the sources additionally suggests that the above mentioned uncertaintyis likely not larger than 3 meters. With errors of this magnitude, HALCA is a useful tool for astrometric studies of close pairs of radio sources.Comment: Accepted for publication in A&A, 5 pages, 5 figures, needs aa.cl

Fully relativistic calculation of magnetic properties of Fe, Co and Ni adclusters on Ag(100)

We present first principles calculations of the magnetic moments and magnetic anisotropy energies of small Fe, Co and Ni clusters on top of a Ag(100) surface as well as the exchange-coupling energy between two single adatoms of Fe or Co on Ag(100). The calculations are performed fully relativistically using the embedding technique within the Korringa-Kohn-Rostoker method. The magnetic anisotropy and the exchange-coupling energies are calculated by means of the force theorem. In the case of adatoms and dimers of iron and cobalt we obtain enhanced spin moments and, especially, unusually large orbital moments, while for nickel our calculations predict a complete absence of magnetism. For larger clusters, the magnitudes of the local moments of the atoms in the center of the cluster are very close to those calculated for the corresponding monolayers. Similar to the orbital moments, the contributions of the individual atoms to the magnetic anisotropy energy strongly depend on the position, hence, on the local environment of a particular atom within a given cluster. We find strong ferromagnetic coupling between two neighboring Fe or Co atoms and a rapid, oscillatory decay of the exchange-coupling energy with increasing distance between these two adatoms.Comment: 8 pages, ReVTeX + 4 figures (Encapsulated Postscript), submitted to PR

Evidence of a radiation belt around a brown dwarf

Radio observations of ultracool dwarfs, objects comprising brown dwarfs and the very lowest mass stars, have mainly focused on analyzing their light-curve and spectral energy distributions providing valuable insights into their magnetic fields. However, spatially-resolved studies of such magnetospheres have been elusive so far. Radio interferometric observations of the brown dwarf LSR J1835+3259 reveal an extended magnetosphere with a morphology compatible with the presence of a radiation belt, similar to that of Jupiter and Earth, consisting of energetic particles confined via magnetic mirroring. Our finding suggests that radio emitting ultracool dwarfs may behave as scaled up versions of Jupiter, validating the connection between dipole-ordered magnetic fields and the presence of belt-like morphologies and aurorae beyond our Solar System.Comment: Submitted on 12 January 2023 to Science. In revie

The Coronal Structure of AB Doradus

We perform a numerical simulation of the corona of the young, rapidly rotating K0 dwarf AB Doradus using a global MHD model. The model is driven by a surface map of the radial magnetic field constructed using Zeeman-Doppler Imaging. We find that the global structure of the stellar corona is dominated by strong azimuthal tangling of the magnetic field due to the rapid rotation. The MHD solution enables us to calculate realistic Alfv\'en surfaces and we can therefore estimate the stellar mass loss rate and angular momentum loss rate without making undue theoretical simplifications. We consider three cases, parametrized by the base density of the corona, that span the range of possible solutions for the system. We find that overall, the mass and angular-momentum loss rates are higher than in the solar case; the mass loss rates are 10 to 500 times higher, and the angular momentum loss rate can be up to $3\times{10}^4$ higher than present day solar values. Our simulations show that this model can be use to constrain the wide parameter space of stellar systems. It also shows that an MHD approach can provide more information about the physical system over the commonly used potential field extrapolation.Comment: 13 pages, 7 figure