The Permeability of Network Boundaries: Strategic Alliances in the Japanese Electronics Industry in the 1990s

This paper looks at the choice of strategic partners for alliance formation in the Japanese electronics industry during the post-bubble economic period 1992-97. Results from a dyad analysis of 128 companies suggest that firms tend to look for partners within their existing vertical keiretsu networks of organizations for alliances that target the creation of resources that build on existing knowledge (production or distribution) but that this common keiretsu effect disappears for alliances that involve new knowledge creation (new product or technology development). The role of corporate networks, environmental uncertainty and their implications for our understanding of strategic alliance formation and the dynamics of social networks are discussed.

The Interior of Jupiter

Jupiter, owing to its large mass and rapid formation, played a crucial role in shaping the solar system as we know it today. Jupiter mostly contains hydrogen and helium (more than 87% by mass), and as such bears a close resemblance to the Sun. However, the Sun has only 2% of its mass in elements other than hydrogen and helium (the heavy elements), whereas Jupiter has between 3 and 13%. The exact amount of these heavy elements in the planet and their distribution are keys to understanding how the solar system formed

CodY Regulates the Activity of the Virulence Quorum Sensor PlcR by Controlling the Import of the Signaling Peptide PapR in Bacillus thuringiensis

In Gram-positive bacteria, cell–cell communication mainly relies on cytoplasmic sensors of the RNPP family. Activity of these regulators depends on their binding to secreted signaling peptides that are imported into the cell. These quorum sensing regulators control important biological functions in bacteria of the Bacillus cereus group, such as virulence and necrotrophism. The RNPP quorum sensor PlcR, in complex with its cognate signaling peptide PapR, is the main regulator of virulence in B. cereus and Bacillus thuringiensis(Bt). Recent reports have shown that the global stationary phase regulator CodY, involved in adaptation to nutritional limitation, is required for the expression of virulence genes belonging to the PlcR regulon. However, the mechanism underlying this regulation was not described. Using genetics and proteomics approaches, we showed that CodY regulates the expression of the virulence genes through the import of PapR. We report that CodY positively controls the production of the proteins that compose the oligopeptide permease OppABCDF, and of several other Opp-like proteins. It was previously shown that the pore components of this oligopeptide permease, OppBCDF, were required for the import of PapR. However, the role of OppA, the substrate-binding protein (SBP), was not investigated. Here, we demonstrated that OppA is not the only SBP involved in the recognition of PapR, and that several other OppA-like proteins can allow the import of this peptide. Altogether, these data complete our model of quorum sensing during the lifecycle of Bt and indicate that RNPPs integrate environmental conditions, as well as cell density, to coordinate the behavior of the bacteria throughout growt

Reconstructing the total shortening history of the NW Himalaya.

The onset of India-Asia contact can be dated with both biostratigraphic analysis of syn-collisional sedimentary successions deposited on each side of the Indus Suture zone, and by radiometric dating of Indian crustal rocks which have undergone subduction to great depths in the earliest subduction-collision stages. These data, together with paleomagnetic data show that the initial contact of the Indian and Asian continental margins occurred at the Paleocene/Eocene boundary, corresponding to 55 ± 2 Ma. Such dating, which is consistent with all available geological evidence, including the record of magnetic anomalies in the Indian ocean and decrease of magmatic activity related to oceanic subduction can thus be considered as accurate and robust. The sedimentary record of the Tethys Himalaya rules out obduction of oceanic allochtons directly onto the Indian continental margin during the Late Cretaceous. The commonly inferred Late Cretaceous ophiolite obduction events may have thus occurred in intra-oceanic setting close to the Asian margin before its final emplacement onto the India margin during the Eocene. Granitoid and sedimentary rocks of the Indian crust, deformed during Permo-Carboniferous rifting, reached a depth of some 100 km about 1 Myr after the final closure of the Neo-Tethys, and began to be exhumed between 50 and 45 Ma. At this stage, the foreland basin sediments from Pakistan to India show significant supply from volcanic arcs and ophiolites of the Indus Suture Zone, indicating the absence of significant relief along the proto-Himalayan belt. Inversion of motion may have occurred within only 5 to 10 Myr after the collision onset, as soon as thicker and buoyant Indian crust chocked the subduction zone. The arrival of thick Indian crust within the convergent zone 50-45 Myr ago led to progressive stabilization of the India/Asia convergent rate and rapid stabilization of the Himalayan shortening rate of about 2 cm.yr-1. This first period also corresponds to the onset of terrestrial detrital sedimentation within the Indus Suture zone and to the Barrovian metamorphism on the Indian side of the collision zone. Equilibrium of the Himalayan thrust belt in terms of amount of shortening vs amount of erosion and thermal stabilization less than 10 Myr after the initial India/Asia contact is defined as the collisional regime. In contrast, the first 5 to 10 Myr corresponds to the transition from oceanic subduction to continental collision, characterized by a marked decrease of the shortening rate, onset of aerial topography, and progressive heating of the convergent zone. This period is defined as the continental subduction phase, accommodating more than 30% of the total Himalayan shortening

Sérendipité et usages : interfaces et outils de recherche dans le cadre de la FRBRisation

International audienc

Inkjet-printed indium sulfide buffer layer for Cu(In,Ga)(S,Se)2 thin film solar cells

We report an environmentally friendly inkjet-printed indium sulfide (In2S3) buffer layer using benign chemistry and processing conditions. A pre-synthesized indium-thiourea compound is dissolved in a mixture of water and ethanol, inkjet printed on a Cu(In,Ga)(S,Se)2 absorber and annealed in air. The buffer layer shows a β-In2S3 structure with few organic impurities and band gap in the range of 2.3 eV. An ultraviolet ozone treatment applied to the surface of the absorber prior to inkjet printing of the precursor is used to improve the wettability of the ink and therefore the surface coverage of the buffer on the absorber layer. The device with a fully covering In2S3 layer shows better open circuit voltage and fill factor than the device with a partially covering In2S3 layer. The best In2S3 device showed a light to electric power conversion efficiency similar to the reference cadmium sulfide buffer layer device. Good wettability conditions are therefore essential for higher efficiency solar cells when the buffer layer is inkjet-printed

The SARS algorithm: detrending CoRoT light curves with Sysrem using simultaneous external parameters

Surveys for exoplanetary transits are usually limited not by photon noise but rather by the amount of red noise in their data. In particular, although the CoRoT spacebased survey data are being carefully scrutinized, significant new sources of systematic noises are still being discovered. Recently, a magnitude-dependant systematic effect was discovered in the CoRoT data by Mazeh & Guterman et al. and a phenomenological correction was proposed. Here we tie the observed effect a particular type of effect, and in the process generalize the popular Sysrem algorithm to include external parameters in a simultaneous solution with the unknown effects. We show that a post-processing scheme based on this algorithm performs well and indeed allows for the detection of new transit-like signals that were not previously detected.Comment: MNRAS accepted. 5 pages, 3 figure

OPV strains circulation in HIV infected infants after National Immunisation Days in Bangui, Central African Republic

<p>Abstract</p> <p>Background</p> <p>Humans are the only host of polioviruses, thus the prospects of global polio eradication look reasonable. However, individuals with immunodeficiencies were shown to excrete vaccine derived poliovirus for long periods of time which led to reluctance to prolong the vaccination campaign for fear of this end result. Therefore, we aimed to assess the duration of excretion of poliovirus after the 2001 National Immunization Days according to Human immunodeficiency virus status.</p> <p>Findings</p> <p>Fifty three children were enrolled. Sequential stool samples were collected in between National Immunisation Days rounds and then every month during one year. Children were classified into 2 groups: no immunodepression (n = 38), immunodepression (n = 15) according to CD4+ lymphocytes cells count. Thirteen poliovirus strains were isolated from 11 children: 5 Human immunodeficiency virus positive and 6 Human immunodeficiency virus negative. None of the children excreted poliovirus for more than 4 weeks. The restriction fragment length polymorphism analysis showed that all strains were of Sabin origin including a unique Polio Sabine Vaccine types 2 and 3 (S2/S3) recombinant.</p> <p>Conclusions</p> <p>From these findings we assume that Human immunodeficiency virus positive children are not a high risk population for long term poliovirus excretion. More powerful studies are needed to confirm our findings.</p