Système de gestion lexicale des ressources termino-ontologiques

The use of services based on a lexical management model would help in the process of searching for information in free text documents. This document is the synthesis of a work carried out within the IAM unit of the CHU of Bordeaux, with the aim of implementing a structure based on a lexical management model so that services and methods can be developed there. The choice of the lexical management model was Ontolex-Lemon, which best met our expectations. The evaluation of this structure was done by integrating four termino-ontological resources, and services and methods such as synonym and polysemous terms detection were integrated.L’utilisation de services se basant sur un modèle de gestion lexicale permettrait d’apporter une aide aux processus de recherche d’informations dans les documents en texte libre. Ce document est la synthèse d’un travail réalisé au sein de l’unité IAM du CHU de Bordeaux, ayant pour but l’implémentation d’une structure se basant sur un modèle de gestion lexicale afin que des services et méthodes puissent y être développés. Le choix du modèle de gestion lexicale s’est porte sur Ontolex-Lemon, qui répondait le mieux à nos attentes. L’évaluation de cette structure a été faite en y intégrant quatre ressources termino-ontologiques, et des services et m´méthodes comme la détection de termes synonymes et polysémiques y ont été intègres

Système de gestion lexicale des ressources termino-ontologiques

The use of services based on a lexical management model would help in the process of searching for information in free text documents. This document is the synthesis of a work carried out within the IAM unit of the CHU of Bordeaux, with the aim of implementing a structure based on a lexical management model so that services and methods can be developed there. The choice of the lexical management model was Ontolex-Lemon, which best met our expectations. The evaluation of this structure was done by integrating four termino-ontological resources, and services and methods such as synonym and polysemous terms detection were integrated.L’utilisation de services se basant sur un modèle de gestion lexicale permettrait d’apporter une aide aux processus de recherche d’informations dans les documents en texte libre. Ce document est la synthèse d’un travail réalisé au sein de l’unité IAM du CHU de Bordeaux, ayant pour but l’implémentation d’une structure se basant sur un modèle de gestion lexicale afin que des services et méthodes puissent y être développés. Le choix du modèle de gestion lexicale s’est porte sur Ontolex-Lemon, qui répondait le mieux à nos attentes. L’évaluation de cette structure a été faite en y intégrant quatre ressources termino-ontologiques, et des services et m´méthodes comme la détection de termes synonymes et polysémiques y ont été intègres

Low‐frequency variability in the Southern Ocean region in a simplified coupled model

International audiencePatterns of interannual variability of the ocean‐atmosphere coupled system in the Southern Hemisphere extratropics are studied with a simple dynamical model in order to determine the basic physical processes of interaction independently of tropical forcing. The model used is an atmospheric quasi‐geostrophic model coupled to a “slab” oceanic mixed layer, which includes mean geostrophic advection by the Antarctic Circumpolar Current (ACC). The ocean‐atmosphere coupling occurs through surface heat fluxes and Ekman current heat advection. In a fully coupled simulation, the atmospheric part of the model, which includes high‐frequency transient eddies at midlatitudes, exhibits a strong Southern Annular Mode (SAM) as the first mode of variability at interannual timescales. The SAM‐related wind anomalies induce Ekman currents in the mixed layer which produce sea surface temperature anomalies. These are then advected along by the ACC. A forced mechanism where the ocean role is reduced to advect the sea surface temperature (SST) appears sufficient to reproduce the main features of the variability. Nevertheless, a positive feedback of the ocean was also found. It operates through anomalous Ekman currents heat advection and contributes to the maintenance of the SST anomaly

Acute respiratory distress syndrome after SARS-CoV-2 infection on young adult population: International observational federated study based on electronic health records through the 4CE consortium.

PurposeIn young adults (18 to 49 years old), investigation of the acute respiratory distress syndrome (ARDS) after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been limited. We evaluated the risk factors and outcomes of ARDS following infection with SARS-CoV-2 in a young adult population.MethodsA retrospective cohort study was conducted between January 1st, 2020 and February 28th, 2021 using patient-level electronic health records (EHR), across 241 United States hospitals and 43 European hospitals participating in the Consortium for Clinical Characterization of COVID-19 by EHR (4CE). To identify the risk factors associated with ARDS, we compared young patients with and without ARDS through a federated analysis. We further compared the outcomes between young and old patients with ARDS.ResultsAmong the 75,377 hospitalized patients with positive SARS-CoV-2 PCR, 1001 young adults presented with ARDS (7.8% of young hospitalized adults). Their mortality rate at 90 days was 16.2% and they presented with a similar complication rate for infection than older adults with ARDS. Peptic ulcer disease, paralysis, obesity, congestive heart failure, valvular disease, diabetes, chronic pulmonary disease and liver disease were associated with a higher risk of ARDS. We described a high prevalence of obesity (53%), hypertension (38%- although not significantly associated with ARDS), and diabetes (32%).ConclusionTrough an innovative method, a large international cohort study of young adults developing ARDS after SARS-CoV-2 infection has been gather. It demonstrated the poor outcomes of this population and associated risk factor

Proportion and associated risk ratio of complication classes for the young compared to old adult with ARDS.

Proportion and associated risk ratio of complication classes for the young compared to old adult with ARDS.</p

Flow chart.

Distribution of patients per group (y.o. = years old).</p

Name, city, country, number of hospitals per HS, number of beds and inpatient discharges/year per HS.

Name, city, country, number of hospitals per HS, number of beds and inpatient discharges/year per HS.</p

Number and percentage of patients per Elixhauser comorbidities for young adult patients with ARDS and non severe young adult patients.

Risk ratio associated in uni-variable analysis for the sub population which had previous hospital visits and considering only the ICD code related to those previous visits (one year and– 14 before the admission). (DOCX)</p

Number and percentage of patients per age groups, per sex, per Elixhauser comorbidities for young adult patients with ARDS and non severe young adult patients.

Risk ratio associated in uni- and multivariable analysis.</p