Comparison between seismic vulnerability models and experimental dynamic properties of existing buildings in France

Elastic fundamental frequency is a key-parameter of simplified seismic design and vulnerability assessment methods. Empirical relationships exist in codes to estimate this frequency but they miss experimental data to validate them accounting for national feature of building design and, above all, corresponding uncertainties. Even if resonance frequency extracted from ambient vibrations may be larger than the elastic frequency (at yield) generally used in earthquake engineering, ambient vibration recordings may provide a large set of data for statistical analysis of periods versus building characteristics relationships. We recorded ambient vibrations and estimated the fundamental frequency of about 60 buildings of various types (RC and masonry) in Grenoble City (France). These data complete the set existing yet, made of 26 RC-buildings of Grenoble (Farsi and Bard 2004) and 28 buildings in Nice (France) (Dunand 2005). Statistical analysis of these experimental data was performed for fundamental frequencies of RC shear wall structures and the results are compared with existing relationships. Only building height or number of stories has a statistical relevancy to estimate the resonance frequency but the variability associated to the proposed relationships is large. Moreover, we compared the elastic part of capacity curves of RC and masonry buildings used in the European Risk-UE method for vulnerability assessment with the experimental frequencies. The variability is also large and the curves may not be consistent with French existing building

Intercultural New Media Studies: The Next Frontier in intercultural Communication

New media (ICT\u27s) are transforming communication across cultures. Despite this revolution in cross cultural contact, communication researchers have largely ignored the impact of new media on intercultural communication. This groundbreaking article defines the parameters of a new field of inquiry called Intercultural New Media Studies (INMS), which explores the intersection between ICT\u27s and intercultural communication. Composed of two research areas—(1) new media and intercultural communication theory and (2) culture and new media—INMS investigates new digital theories of intercultural contact as well as refines and expands twentieth-century intercultural communication theories, examining their salience in a digital world. INMS promises to increase our understanding of intercultural communication in a new media age and is the next frontier in intercultural communication

Cosmetics Alter Biologically-Based Factors of Beauty: Evidence from Facial Contrast

The use of cosmetics by women seems to consistently increase their attractiveness. What factors of attractiveness do cosmetics alter to achieve this? Facial contrast is a known cue to sexual dimorphism and youth, and cosmetics exaggerate sexual dimorphisms in facial contrast. Here, we demonstrate that the luminance contrast pattern of the eyes and eyebrows is consistently sexually dimorphic across a large sample of faces, with females possessing lower brow contrasts than males, and greater eye contrast than males. Red-green and yellow-blue color contrasts were not found to differ consistently between the sexes. We also show that women use cosmetics not only to exaggerate sexual dimorphisms of brow and eye contrasts, but also to increase contrasts that decline with age. These findings refine the notion of facial contrast, and demonstrate how cosmetics can increase attractiveness by manipulating factors of beauty associated with facial contrast

Does "chaining" always really work towards compliance gaining? The case of the "but you are free" technique and social proof applied to charitable donation

The chaining procedure consists in linking together two or more compliance gaining strategies in order to obtain greater behavioral compliance. In two studies we tested chaining that included two compliance gaining procedures: the "but you are free" technique (BYAF) and social proof (SP). A total of 2204 passersby were approached in different countries (France, Tunisia, China and Moldavia). They were asked to donate money for cancer research with, respectively, a control formulation, a BYAF formulation, a SP formulation or a BYAF + SP formulation. Results indicate that chaining did not work because the BYAF + SP condition produced the same behavioral compliance as BYAF or SP separately (studies 1 and 2). Furthermore, we analyzed the participants' justifications after complying with or rejecting the request and the reasons were substantially the same under each condition (study 2). Failure to observe the chaining process is interpreted through theoretical explanations whereby BYAF and SP are antagonistic

Facial Cosmetics and Attractiveness: Comparing the Effect Sizes of Professionally-Applied Cosmetics and Identity

Forms of body decoration exist in all human cultures. However, in Western societies, women are more likely to engage in appearance modification, especially through the use of facial cosmetics. How effective are cosmetics at altering attractiveness? Previous research has hinted that the effect is not large, especially when compared to the variation in attractiveness observed between individuals due to differences in identity. In order to build a fuller understanding of how cosmetics and identity affect attractiveness, here we examine how professionally-applied cosmetics alter attractiveness and compare this effect with the variation in attractiveness observed between individuals. In Study 1, 33 YouTube models were rated for attractiveness before and after the application of professionally-applied cosmetics. Cosmetics explained a larger proportion of the variation in attractiveness compared with previous studies, but this effect remained smaller than variation caused by differences in attractiveness between individuals. Study 2 replicated the results of the first study with a sample of 45 supermodels, with the aim of examining the effect of cosmetics in a sample of faces with low variation in attractiveness between individuals. While the effect size of cosmetics was generally large, between-person variability due to identity remained larger. Both studies also found interactions between cosmetics and identity-more attractive models received smaller increases when cosmetics were worn. Overall, we show that professionally- applied cosmetics produce a larger effect than self-applied cosmetics, an important theoretical consideration for the field. However, the effect of individual differences in facial appearance is ultimately more important in perceptions of attractiveness

Work-related risk factors for incidence of lateral epicondylitis in a large working population

Objectives This study aims to estimate the association between repeated measures of occupational risk factors and the incidence of lateral epicondylitis in a large working population. Methods A total of 3710 workers in a French region were included in 2002–2005, and among them 1046 had a complete follow-up in 2007–2010. At both stages, occupational health physicians assessed the presence of lateral epicondylitis and workers self-reported their occupational exposures. Poisson models were performed to assess the incidence rate ratios (IRR) separately by sex using multiple imputed data. Results The annual incidence rate of lateral epicondylitis was estimated as 1.0 [95% confidence interval (95% CI) 0.7–1.3] per 100 workers among men and 0.9 (95% CI 0.6–1.3) among women. Workers aged >45 years had higher incidence than those aged <30 years (significant at 10%). Among men, high physical exertion combined with elbow flexion/extension or extreme wrist bending (>2 hours/day) was a risk factor, with an age-adjusted IRR of 3.2 (95% CI 1.5–6.4) for workers exposed at both questionnaires [3.3 (95% CI 1.4–7.6) among women]. Conclusions This study highlights the importance of temporal dimensions for occupational risk factors on the incidence of lateral epicondylitis. Further research should evaluate the risk associated with the duration and repetition of occupational exposure on the incidence of lateral epicondylitis

A Broadband Laboratory Study of the Seismic Properties of Cracked and Fluid-Saturated Synthetic Glass Media

For better understanding of frequency dependence (dispersion) of seismic wave velocities caused by stress‐induced fluid flow, broadband laboratory measurements were performed on a suite of synthetic glass media containing both equant pores and thermal cracks. Complementary forced oscillation, resonant bar, and ultrasonic techniques provided access to millihertz‐hertz frequencies, ~1 kHz frequency, and ~1 MHz frequency, respectively. The wave speeds or effective elastic moduli and associated dissipation were measured on samples under dry, argon‐ or nitrogen‐saturated, and water‐saturated conditions in sequence. The elastic moduli, in situ permeability, and crack porosity inferred from in situ X‐ray computed tomography all attest to strong pressure‐induced crack closure for differential (confining‐minus‐pore) pressures <30 MPa, consistent with zero‐pressure crack aspect ratios <4 × 10−4. The low permeabilities of these materials allow access to undrained conditions, even at subhertz frequencies. The ultrasonically measured elastic moduli reveal consistently higher shear and bulk moduli upon fluid saturation—diagnostic of the saturated‐isolated regime. For a glass rod specimen, containing cracks but no pores, saturated‐isolated conditions apparently persist to subhertz frequencies—requiring in situ aspect ratios (minimum/maximum dimension) <10−5. In marked contrast, the shear modulus measured at subhertz frequencies on a cracked glass bead specimen of 5% porosity, is insensitive to fluid saturation, consistent with the Biot‐Gassmann model for the saturated‐isobaric regime. The measured dispersion of the shear modulus approaches 10% over the millihertz‐megahertz frequency range for the cracked and fluid‐saturated media—implying that laboratory ultrasonic data should be used with care in the interpretation of field data

Evolutionary Mechanisms of Long-Term Genome Diversification Associated With Niche Partitioning in Marine Picocyanobacteria.

Marine picocyanobacteria of the genera Prochlorococcus and Synechococcus are the most abundant photosynthetic organisms on Earth, an ecological success thought to be linked to the differential partitioning of distinct ecotypes into specific ecological niches. However, the underlying processes that governed the diversification of these microorganisms and the appearance of niche-related phenotypic traits are just starting to be elucidated. Here, by comparing 81 genomes, including 34 new Synechococcus, we explored the evolutionary processes that shaped the genomic diversity of picocyanobacteria. Time-calibration of a core-protein tree showed that gene gain/loss occurred at an unexpectedly low rate between the different lineages, with for instance 5.6 genes gained per million years (My) for the major Synechococcus lineage (sub-cluster 5.1), among which only 0.71/My have been fixed in the long term. Gene content comparisons revealed a number of candidates involved in nutrient adaptation, a large proportion of which are located in genomic islands shared between either closely or more distantly related strains, as identified using an original network construction approach. Interestingly, strains representative of the different ecotypes co-occurring in phosphorus-depleted waters (Synechococcus clades III, WPC1, and sub-cluster 5.3) were shown to display different adaptation strategies to this limitation. In contrast, we found few genes potentially involved in adaptation to temperature when comparing cold and warm thermotypes. Indeed, comparison of core protein sequences highlighted variants specific to cold thermotypes, notably involved in carotenoid biosynthesis and the oxidative stress response, revealing that long-term adaptation to thermal niches relies on amino acid substitutions rather than on gene content variation. Altogether, this study not only deciphers the respective roles of gene gains/losses and sequence variation but also uncovers numerous gene candidates likely involved in niche partitioning of two key members of the marine phytoplankton

Sensitive detection methods are key to identify secondary EGFR c.2369C&gt;T p.(Thr790Met) in non-small cell lung cancer tissue samples

Background: Correct identification of the EGFR c.2369C>T p.(Thr790Met) variant is key to decide on a targeted therapeutic strategy for patients with acquired EGFR TKI resistance in non-small cell lung cancer. The aim of this study was to evaluate the correct detection of this variant in 12 tumor tissue specimens tested by 324 laboratories participating in External Quality Assessment (EQA) schemes. Methods: Data from EQA schemes were evaluated between 2013 and 2018 from cell lines (6) and resections (6) containing the EGFR c.2369C>T p.(Thr790Met) mutation. Adequate performance was defined as the percentage of tests for w