69 research outputs found
4-(4-Bromophenyl)-6-(4-chlorophenyl)pyrimidin-2-ylamine
The title compound, C16H11BrClN3, contains pairs of molecules lying about inversion centers linked by amino–pyrimidine N—H⋯N hydrogen bonds. The eight-membered rings thus formed are represented by the R
2
2(8) motif in graph-set notation. The second H atom of the amine group shows a rather weak interaction with two Br atoms, resulting in bifurcated N—H⋯(Br,Br) hydrogen bonds. The dihedral angles between the mean planes of the benzene rings and the mean plane of the heterocyclic ring are 8.98 (15) and 35.58 (10)°. The Br and Cl atoms show substitutional disorder, with site-occupancy factors of 0.599 (2) and 0.401 (2), respectively
An efficient one-pot synthesis of novel pyrimidoquinoline derivatives under microwave irradiation without catalyst
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