Residence for a suburban estate

Thesis (B.S.)--University of Illinois, 1905.Typescript.Bound with 3 other theses. IU-

Addressing Reference Perishability : The Availability of Web-based Resources Cited in Academic Journals

A tremendous volume of information is now available on the World Wide Web (web). Researchers have begun to tap this resource, and reference web sites in their publications. However, web-based sources may not be available in the given location when readers attempt to access the referenced material. This article considers the longevity and malleability of web-based information sources, reasons for the loss of referenced sources, and how using this knowledge resource may affect the academic tradition of building cumulative knowledge

Analytics in the Business School: Insights from the Literature

The demand for business and data analysts is growing. The business school is well positioned to offer programs to meet these needs. This paper presents both the findings from a review of the existing literature on data analytics job roles, skills required for those roles and also feedback from industry experts on findings. Three different types of articles are included in the design: faculty writing about their personal experiences and observations (faculty voice), data gathered from expert practitioners and other academics (nonresident expertise), and empirical data from online job service platforms (content analysis). The narrative review method is used to integrate these disparate sources of information and deliver cohesive observations. This knowledge can be used to build better analytics programs in business schools

Institutional Investors and Executive Compensation

Due to institutional investors' increasing ownership and interest in corporate governance, we hypothesize that the presence of institutional investors is associated with certain executive compensation structures. We find a significantly negative relation between the level of compensation and the concentration of institutional ownership, suggesting that institutions serve a monitoring role in the shareholder-manager agency problem. We further find a significantly positive relation between the pay-for-performance sensitivity of executive compensation and both the level and concentration of institutional ownership. These results suggest that the institutions act as a complement rather than a substitute to incentive compensation in mitigating the agency problem

Expectation Formation in the Information System Development Process

The concept of consumer expectations has been widely used by information systems (IS) researchers to explain the outcome of information system development (ISD) efforts (Suh et al, 1994; Lawrence and Low, 1993; Ginzberg, 1981). These IS studies assume that users are IS consumers. However, ISD is substantially different from many other product development efforts. Information systems are highly customized, requiring more user involvement in the development. Also, analysts and users can interact directly, rather than through indirect mechanisms requiringlimited consumer input such as marketing research, focus groups, and consumer attitude surveys. Therefore, the ISD process provides more opportunities to develop and manage user expectations. This fact has been overlooked by the IS literature, which mainconcern is in linking user expectations to perceived system performance. Based on this observation, this paper contributes by explaining how user expectations are formed and updated throughout an ISD process. Using the ISD model developed by Newman and Robey (1992), we conceptualize user expectations as two distinct constructs, desiredand predictiveexpectations (Spreng and Olshavsky, 1992), which are modified through a series of encounters and episodes

Aligning Business Analytics Programs with Industry Required Knowledge, Skills and Abilities

This paper describes results from a topic modeling analysis of online data analytics-related job advertisements. Five distinct clusters emerged, each with a focus on different knowledge, skills and abilities (KSAs) profiles. We labelled these clusters big data, systems analysis, business, healthcare, and technical research. Identification of these clusters provides a framework that can be used by information systems and business analytics faculty to offer customized and specialized information systems and business analytics programs that prepare graduates to fill specific roles in the data ecosystem of the workplace

The Impact of CEO Turnover on Equity Volatility

A change in executive leadership is a significant event in the life of a firm. Our paper investigates a potentially significant consequence of a CEO turnover: a change in equity volatility. We develop several hypotheses about how CEO changes might affect stock price volatility, and test these hypotheses using a sample of 872 CEO changes over the 1979-1995 period. We find that volatility increases following a CEO turnover, even for the most frequent type, when a CEO leaves voluntarily and is replaced by someone from inside the firm. Our results indicate that forced turnovers, which are expected to result in large strategy changes, increase volatility more than voluntary turnovers. Outside successions, which are expected to result in a successor CEO with less certain skill in managing the firm's operations, increase volatility more than inside turnovers. We also document a greater stock-price response to earnings announcements around CEO turnover, consistent with more informative signals of value driving the increased volatility. Controls for firm-specific characteristics indicate that the volatility changes cannot be entirely attributed to factors such as changes in firm operations, firm size, and both volatility change and performance prior to the turnover

Method for Simultaneous Quantitation of Free Carrier Protein and Free Polysaccharide in Glycoconjugate Vaccines by High Performance Liquid Chromatography

Disease caused by bacterial infections affect children and adults worldwide can be potentially life-threatening. Bacterial strains, such as Staphylococcus aureus and Streptococcus pnueumoniae (pneumococcus), express capsular polysaccharides on their surface, which act as a virulence factor for evading the immune system and are structurally unique depending on the serotype. Vaccines designed against the capsular polysaccharides have shown to be effective in reducing the incident rate of disease caused by bacterial injections. Glycoconjugate vaccines comprise large molecular mass bacterial capsular polysaccharides conjugated to a carrier protein, which helps activate T cells that trigger immunological memory functions. Un conjugated (free) carrier protein and polysaccharide are critical attributes typically included in analytical testing for glycoconjugate vaccines and must be monitored throughout the vaccine development process. High levels of free polysaccharide or carrier protein may be indicative of poor conjugation efficiency or product degradation caused by manufacturing inconsistencies, formulation, or storage conditions. In this work, we will present the development of an HPLC method to simultaneously quantitate free carrier protein and free polysaccharide in a glycoconjugate vaccine drug substance. This method would be developed for two S. aureus glycoconjugate drug substances, CP5-CRM197 and CP8-CRM197. Initial work focused on using hydrophobic interaction chromatography (HIC) as the mode of separation by utilizing the often-ignored separation space prior to the void volume. However, the separation proved to be difficult in a 1D format due to the complexity of the sample mixture and the chromatographic behavior of the glycoconjugate. Therefore, a 2D-LC approach was taken to separate and quantitate the free carrier protein and free polysaccharide in the two S. aureus glycoconjugate drug substances. This work focused on the development of SEC and RPLC methods, 2D-LC instrumentation design, 2D-LC method development, and assay performance. Results were then compared to results from current technologies in place based on capillary electrophoresis (CE) for the quantitation of free carrier protein and free polysaccharide to assess the feasibility of supporting manufacturing process and formulation development studies. In addition, this methodology was explored as a potential platform technology for monitoring free carrier protein and polysaccharide in other glycoconjugate vaccine projects in the development pipeline

The Ursinus Weekly, December 12, 1949

Women select four to appear on ballot for May sovereign • Twelve receive Who\u27s who honors • Students anticipate traditional roster of yuletide events • Men\u27s council clarifies stand on frosh customs • Music group plans January 5 concert • Yuletide setting pervades starlight ball • Messiah ensemble wins new acclaim • Ruby sells greeting cards, plans welcome-back dance • Bear quintet loses 73-54 to strong Moravian five • Cubs score victory in greyhound game with 44-36 margin • Court coeds report for daily practice; experience lacking • Jayvees win third; down Lehigh 48-46 in thrilling battle • Ursinus rallies too late; Engineers triumph 49-42 • Players to receive fall sport awardshttps://digitalcommons.ursinus.edu/weekly/1580/thumbnail.jp