150 research outputs found
Diquark condensation at strong coupling
The possibility of diquark condensation at sufficiently large baryon chemical
potential and zero temperature is analyzed in QCD at strong coupling. In
agreement with other strong coupling analysis, it is found that a first order
phase transition separates a low density phase with chiral symmetry
spontaneously broken from a high density phase where chiral symmetry is
restored. In none of the phases diquark condensation takes place as an
equilibrium state, but, for any value of the chemical potential, there is a
metastable state characterized by a non-vanishing diquark condensate. The
energy difference between this metastable state and the equilibrium state
decreases with the chemical potential and is minimum in the high density phase.
The results indicate that there is attraction in the quark-quark sector also at
strong coupling, and that the attraction is more effective at high baryon
density, but for infinite coupling it is not enough to produce diquark
condensation. It is argued that the absence of diquark condensation is not a
peculiarity of the strong coupling limit, but persists at sufficiently large
finite couplings.Comment: 10 pages, 2 figures. An important discussion concerning the extension
of the results to finite couplings adde
Delayed Gratification in Blacks: A Critical Review
Research on the delay of gratification in Blacks was critically reviewed. The methodology typically em ployed to investigate this construct involves offering the individual a choice of obtaining either a small, im mediate reward or a large, delayed reward. Contrary to previous reports, it is argued here that the evidence divides published studies into those demonstrating overall patterns of nonpreference for delayed versus immediate rewards and those demonstrating overall or partial patterns of preference for delayed rewards among Blacks. Little empirical evidence is provided in the literature of a tendency for Blacks to prefer im mediate gratification, or of the relationship of such behavior to other personality characteristics.Yeshttps://us.sagepub.com/en-us/nam/manuscript-submission-guideline
Heavy quarkonium: progress, puzzles, and opportunities
A golden age for heavy quarkonium physics dawned a decade ago, initiated by
the confluence of exciting advances in quantum chromodynamics (QCD) and an
explosion of related experimental activity. The early years of this period were
chronicled in the Quarkonium Working Group (QWG) CERN Yellow Report (YR) in
2004, which presented a comprehensive review of the status of the field at that
time and provided specific recommendations for further progress. However, the
broad spectrum of subsequent breakthroughs, surprises, and continuing puzzles
could only be partially anticipated. Since the release of the YR, the BESII
program concluded only to give birth to BESIII; the -factories and CLEO-c
flourished; quarkonium production and polarization measurements at HERA and the
Tevatron matured; and heavy-ion collisions at RHIC have opened a window on the
deconfinement regime. All these experiments leave legacies of quality,
precision, and unsolved mysteries for quarkonium physics, and therefore beg for
continuing investigations. The plethora of newly-found quarkonium-like states
unleashed a flood of theoretical investigations into new forms of matter such
as quark-gluon hybrids, mesonic molecules, and tetraquarks. Measurements of the
spectroscopy, decays, production, and in-medium behavior of c\bar{c}, b\bar{b},
and b\bar{c} bound states have been shown to validate some theoretical
approaches to QCD and highlight lack of quantitative success for others. The
intriguing details of quarkonium suppression in heavy-ion collisions that have
emerged from RHIC have elevated the importance of separating hot- and
cold-nuclear-matter effects in quark-gluon plasma studies. This review
systematically addresses all these matters and concludes by prioritizing
directions for ongoing and future efforts.Comment: 182 pages, 112 figures. Editors: N. Brambilla, S. Eidelman, B. K.
Heltsley, R. Vogt. Section Coordinators: G. T. Bodwin, E. Eichten, A. D.
Frawley, A. B. Meyer, R. E. Mitchell, V. Papadimitriou, P. Petreczky, A. A.
Petrov, P. Robbe, A. Vair
Does technology and Innovation Management improve Market Position? Empirical Evidence from Innovating Firms in South Africa
There is a growing recognition of the central role of technology and knowledge management for market success of organizations. Little is empirically know, however, about this relationship. Drawing on the South African Innovation Survey, a unique dataset on innovative behavior of South African firms in manufacturing and services, this paper investigates the question to what extent and in which ways do technology and innovation management activities affect firmsâ market position. Findings show that conducting technology strategy activities pays out. Moreover, especially a combination of internal and external technology audits seems to be beneficial for organizational performance
Phase II Study of Lapatinib in Recurrent or Metastatic Epidermal Growth Factor Receptor and/or erbB2 Expressing Adenoid Cystic Carcinoma and NonâAdenoid Cystic Carcinoma Malignant Tumors of the Salivary Glands
PURPOSE: Expression of erbB2 and/or epidermal growth factor receptor (EGFR) is associated with biologic aggressiveness and poor prognosis in malignant salivary gland tumors (MSGTs). This phase II study was conducted to determine the antitumor activity of lapatinib, a dual inhibitor of EGFR and erbB2 tyrosine kinase activity, in MSGTs.
PATIENTS AND METHODS: Patients with progressive, recurrent, or metastatic adenoid cystic carcinoma (ACC) immunohistochemically expressing at least 1+ EGFR and/or 2+ erbB2 were treated with lapatinib 1,500 mg daily, in a two-stage cohort. Patients with non-ACC MSGTs were treated as a separate single-stage cohort.
RESULTS: Of 62 patients screened, 29 of 33 (88%) ACC and 28 of 29 (97%) non-ACC patients expressed EGFR and/or erbB2. Forty patients with progressive disease were enrolled onto the study. Among 19 assessable ACC patients, there were no objective responses, 15 patients (79%) had stable disease (SD), nine patients (47%) had SD > or = 6 months, and four patients (21%) had progressive disease (PD). For 17 assessable non-ACC patients, there were no objective responses, eight patients (47%) had SD, four patients (24%) had SD > or = 6 months, and nine patients (53%) had PD. The most frequent adverse events were grade 1 to 2 diarrhea, fatigue, and rash. Eight paired tumor biopsies for correlative studies were procured; results did not correlate with clinical outcome.
CONCLUSION: Although no responses were observed, lapatinib was well tolerated, with prolonged tumor stabilization of > or = 6 months in 36% (95% CI, 21% to 54%) of assessable patients. The antitumor effects of lapatinib in MGSTs appear mainly cytostatic, hence evaluation of other molecular targeted agents, or combinations with lapatinib, may be considered. Continued efforts should be made to gain better understanding into the biology of this heterogeneous group of malignancies
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