Gentlemen landowners and the middle classes of Bromley: the transfer of power and wealth? 1840-1914

The central driving force behind this thesis was to study and analyse the balance of power, influence and wealth held by the landed gentry and the middle classes during the period 1840 to 1914. This was accomplished by focusing on the town of Bromley, Kent, which historians and modern commentators alike have championed as the archetypal middle-class suburb. The thesis begins with an in-depth examination of the origins, ideals and actions of the small group of individuals who, in 1840, owned between them the majority of land in the town. Findings about the local gentry challenge existing theories about landowners' alleged antipathy towards commercial interests and show that landowners were not averse to exploiting prevailing economic conditions to their own financial gain. Gradually the local gentry's 'social' power and influence was surrendered to the middle classes which were gaining in wealth and self-confidence. Even though the socio-economic composition of the local middle class was increasingly diverse, there existed no conspicuous divergence in their aspirations or intentions. Indeed, unity of purpose intensified their impact upon the social and economic life of the community, as well as upon prevailing ideals. An ever-growing influx of commuters residing in the town, notably affluent financiers, merchants and professionals working in the City of London, occasionally challenged this unity over demands for improvements in facilities for urban - or suburban - living. However, in the long run these wealthy commuters were adopted as the 'new' elite of local society, helping to promote deferential and paternalistic relationships in a class that was drawn together within a complex web of social, cultural and economic ties. Whilst social harmony was secured by such ties, an obsession with image and perceived status helped preserve social ranks and social distinctions, of which geographical segregation became the most overt illustration. Such were the middle classes' fears of social degradation that they raised a united defence against the emergence of radicalism and socialism. This helped Bromley to emerge, or to be seen to emerge, as the most middle-class of English suburbs, even though this misjudges its more complex Victorian and Edwardian past

Effect of coherent noise on single-station direction of arrival estimation

Polarization analysis of multi-component seismic data is used in both exploration seismology and earthquake seismology. In single-station polarization processing, it is generally assumed that any noise present in the window of analysis is incoherent, i.e., does not correlate between components. This assumption is often violated in practice because several overlapping seismic events may be present in the data. The additional arrival(s) to that of interest can be viewed as coherent noise. This paper quantifies the error because of coherent noise interference. We first give a general theoretical analysis of the problem. A simple mathematical wavelet is then used to obtain a closed-form solution to the principal direction estimated for a transient incident signal superposed with a time-shifted, unequal amplitude version of itself, arriving at an arbitrary angle to the first wavelet. The effects of relative amplitude, arrival angle, and the time delay of the two wavelets on directional estimates are investigated. Even for small differences in angle of arrival, there may be significant error (>10°) in the azimuth estimat

Collection of Biological Material for Commercial Genomic Testing in Beef

This fact sheet describes collecting biological material for commercial genomic testing of beef cattle. It includes a description of materials needed, methods of collecting including blood, ear notching, or tissue collection, and how to ship and store samples

Verifying likelihoods for low template DNA profiles using multiple replicates

AbstractTo date there is no generally accepted method to test the validity of algorithms used to compute likelihood ratios (LR) evaluating forensic DNA profiles from low-template and/or degraded samples. An upper bound on the LR is provided by the inverse of the match probability, which is the usual measure of weight of evidence for standard DNA profiles not subject to the stochastic effects that are the hallmark of low-template profiles. However, even for low-template profiles the LR in favour of a true prosecution hypothesis should approach this bound as the number of profiling replicates increases, provided that the queried contributor is the major contributor. Moreover, for sufficiently many replicates the standard LR for mixtures is often surpassed by the low-template LR. It follows that multiple LTDNA replicates can provide stronger evidence for a contributor to a mixture than a standard analysis of a good-quality profile. Here, we examine the performance of the likeLTD software for up to eight replicate profiling runs. We consider simulated and laboratory-generated replicates as well as resampling replicates from a real crime case. We show that LRs generated by likeLTD usually do exceed the mixture LR given sufficient replicates, are bounded above by the inverse match probability and do approach this bound closely when this is expected. We also show good performance of likeLTD even when a large majority of alleles are designated as uncertain, and suggest that there can be advantages to using different profiling sensitivities for different replicates. Overall, our results support both the validity of the underlying mathematical model and its correct implementation in the likeLTD software

Blurring the boundaries of the Mackintosh room

In this paper we describe a prototype interactive systemsupporting a shared synchronous experience for physical,World Wide Web and virtual reality visitors to anexhibition devoted to the designer and architect C.R.Mackintosh. The system provides awareness betweenvisitors that spans multiple media while also providinglocation- and device-sensitive content to each visitor

Introduction: Real Time Monitoring for the Most Vulnerable – Investing in Common Guidance for Equity and Quality

Growth in the use of real?time digital information for monitoring has been rapid in developing countries across all the social sectors, and in the health sector has been remarkable. Commonly these Real Time Monitoring (RTM) initiatives involve partnerships between the state, civil society, donors and the private sector. There are differences between partners in understanding objectives, and further divergence often occurs due to adoption of specific technology?driven approaches and because profit?making is a part of the equation for some partners. With the swarming, especially of pilot mHealth initiatives, in many countries there is risk of chaotic disconnects, of confrontation between rights and profits, and of overall failure to encourage appropriate alliances to build sustainable and effective national RTM systems. What is needed is a country?led process for strengthening the quality and equity sensitivity of real?time monitoring initiatives. This article proposes the development of an effective learning and action agenda centred on the adoption of common guidance

Contesting control: journeys through surrender, self-awareness and looseness of control in embodied interaction

As Human-Computer Interaction (HCI) engages with technologies that sense and actuate the body, there is a need to reconsider the human bodily experience. We present three case studies that each involve different forms of bodily experience: a breath-controlled amusement ride, a brain-controlled film, and an interactive musical duet with a physically actuated piano. We introduce a conceptual framework to describe how control becomes contested between human and computer in such experiences, using the three dimensions of: surrender of control, self-awareness of control, and looseness of control. We reveal how our experiences took users on journeys through control that traversed the space of these dimensions. We propose that our framework is not only relevant to playful cultural experiences, such as those charted in our case studies, but can also inform the design of embodied interaction more widely by emphasising the human experience of control when engaging with autonomous and bodily-focused systems, from future robots and vehicles to today’s gaze, speech and gestural interfaces

Elective Open Suprarenal Aneurysm Repair in England from 2000 to 2010 an Observational Study of Hospital Episode Statistics

Background: Open surgery is widely used as a benchmark for the results of fenestrated endovascular repair of complex abdominal aortic aneurysms (AAA). However, the existing evidence stems from single-centre experiences, and may not be reproducible in wider practice. National outcomes provide valuable information regarding the safety of suprarenal aneurysm repair. Methods: Demographic and clinical data were extracted from English Hospital Episodes Statistics for patients undergoing elective suprarenal aneurysm repair from 1 April 2000 to 31 March 2010. Thirty-day mortality and five-year survival were analysed by logistic regression and Cox proportional hazards modeling. Results: 793 patients underwent surgery with 14% overall 30-day mortality, which did not improve over the study period. Independent predictors of 30-day mortality included age, renal disease and previous myocardial infarction. 5-year survival was independently reduced by age, renal disease, liver disease, chronic pulmonary disease, and known metastatic solid tumour. There was significant regional variation in both 30-day mortality and 5-year survival after risk-adjustment. Regional differences in outcome were eliminated in a sensitivity analysis for perioperative outcome, conducted by restricting analysis to survivors of the first 30 days after surgery. Conclusions: Elective suprarenal aneurysm repair was associated with considerable mortality and significant regional variation across England. These data provide a benchmark to assess the efficacy of complex endovascular repair of supra-renal aneurysms, though cautious interpretation is required due to the lack of information regarding aneurysm morphology. More detailed study is required, ideally through the mandatory submission of data to a national registry of suprarenal aneurysm repair

Endovascular or open repair strategy for ruptured abdominal aortic aneurysm: 30 day outcomes from IMPROVE randomised trial.

OBJECTIVE: To assess whether a strategy of endovascular repair (if aortic morphology is suitable, open repair if not) versus open repair reduces early mortality for patients with suspected ruptured abdominal aortic aneurysm. DESIGN: Randomised controlled trial. SETTING: 30 vascular centres (29 UK, 1 Canadian), 2009-13. PARTICIPANTS: 613 eligible patients (480 men) with a clinical diagnosis of ruptured aneurysm. INTERVENTIONS: 316 patients were randomised to the endovascular strategy (275 confirmed ruptures, 174 anatomically suitable for endovascular repair) and 297 to open repair (261 confirmed ruptures). MAIN OUTCOME MEASURES: 30 day mortality, with 24 hour and in-hospital mortality, costs, and time and place of discharge as secondary outcomes. RESULTS: 30 day mortality was 35.4% (112/316) in the endovascular strategy group and 37.4% (111/297) in the open repair group: odds ratio 0.92 (95% confidence interval 0.66 to 1.28; P=0.62); odds ratio after adjustment for age, sex, and Hardman index 0.94 (0.67 to 1.33). Women may benefit more than men (interaction test P=0.02) from the endovascular strategy: odds ratio 0.44 (0.22 to 0.91) versus 1.18 (0.80 to 1.75). 30 day mortality for patients with confirmed rupture was 36.4% (100/275) in the endovascular strategy group and 40.6% (106/261) in the open repair group (P=0.31). More patients in the endovascular strategy than in the open repair group were discharged directly to home (189/201 (94%) v 141/183 (77%); P<0.001). Average 30 day costs were similar between the randomised groups, with an incremental cost saving for the endovascular strategy versus open repair of £1186 (€1420; $1939) (95% confidence interval -£625 to £2997). CONCLUSIONS: A strategy of endovascular repair was not associated with significant reduction in either 30 day mortality or cost. Longer term cost effectiveness evaluations are needed to assess the full effects of the endovascular strategy in both men and women. TRIAL REGISTRATION: Current Controlled Trials ISRCTN48334791

Examination of England’s New Medicine Service (NMS) of complex health care interventions in community pharmacy

Background: Community pharmacies are increasingly commissioned to deliver new, complex health interventions in response to the growing demands on family doctors and secondary health care services. Little is known about how these complex interventions are being accommodated and translated into the community pharmacy setting and whether their aims and objectives are realized in practice. The New Medicine Service (NMS) is a complex medicine management intervention that aims to support patients’ adherence to newly prescribed medicines for a long-term condition. Objective: This study explores the recent implementation of the NMS in community pharmacies across England. It also seeks to understand how the service is becoming manifest in practice and what lessons can be learned for future service implementation. Methods: Structured, organizational ethnographic observations and in situ workplace interviews with pharmacists and support staff were undertaken within 23 English community pharmacies. Additionally, one-toone, semi-structured interviews were carried out with 47 community pharmacists and 11 general practitioners (GPs). Observational and interview data were transcribed and analysed thematically and guided by Damschroder’s consolidated framework for implementation research. Results: The NMS workload had been implemented and absorbed into pharmacists’ daily routines alongside existing responsibilities with no extra resources and little evidence of reduction in other responsibilities. Pharmacists were pragmatic, simplifying, and adapting the NMS to facilitate its delivery and using discretion to circumvent perceived non-essential paperwork. Pharmacist understanding of the NMS was found to impact on what they believed should be achieved from the service. Despite pharmacists holding positive views about the value of the NMS, not all were convinced of its perceived benefits and necessity, with reports that many consultations did not identify any problems with the patients’ medicines. GPs were generally supportive of the initiative but were unaware of the service or potential benefits. Poorly developed existing pharmacist-GP relationships impeded implementation. Conclusions: This study identifies the multifaceted and complex processes involved in implementing a new community pharmacy service in England. Community pharmacy workflow, infrastructure, and public and professional relationships all affect NMS implementation. Greater prior engagement with the pharmacy workforce and GPs, robust piloting and a phased rollout together with ongoing support and updates, are potentials strategies to ensure future implementation of pharmacy services meet their intended aims in practice