Stochastic sea state for SRB studies

Ocean surface characteristics at two locations were studied for a space shuttle solid rocket booster ocean impact and recovery analysis. Probability distributions of wave heights, wave slopes, wave velocities, ocean currents, and 1-kilometer altitude winds were formulated. Procedures for generating ocean wave simulations are described

Application of Markov chain theory to ASTP natural environment launch criteria at Kennedy Space Center

To aid the planning of the Apollo Soyuz Test Program (ASTP), certain natural environment statistical relationships are presented, based on Markov theory and empirical counts. The practical results are in terms of conditional probability of favorable and unfavorable launch conditions at Kennedy Space Center (KSC). They are based upon 15 years of recorded weather data which are analyzed under a set of natural environmental launch constraints. Three specific forecasting problems were treated: (1) the length of record of past weather which is useful to a prediction; (2) the effect of persistence in runs of favorable and unfavorable conditions; and (3) the forecasting of future weather in probabilistic terms

Statistical analysis of flight times for space shuttle ferry flights

Markov chain and Monte Carlo analysis techniques are applied to the simulated Space Shuttle Orbiter Ferry flights to obtain statistical distributions of flight time duration between Edwards Air Force Base and Kennedy Space Center. The two methods are compared, and are found to be in excellent agreement. The flights are subjected to certain operational and meteorological requirements, or constraints, which cause eastbound and westbound trips to yield different results. Persistence of events theory is applied to the occurrence of inclement conditions to find their effect upon the statistical flight time distribution. In a sensitivity test, some of the constraints are varied to observe the corresponding changes in the results

Research into the feasibility of thin metal and oxide film capacitors Interim scientific report

Feasibility of thin metal and oxide film capacitor

Amenities and the labor earnings function

I was unable to copy/paste the abstract, but the paper argues that amenities exert an important effect on wage differentials over space. Indeed, we show that as much has half of the apparent effect of unionization on wages is actually compensation for less desirable climate in locations that are most unionized.amenities; climate; weather; wage compensation; return to unionization

Research into the feasibility of thin metal and oxide film capacitors

Feasibility of thin metal and oxide film capacitor

Estimation of peak winds from hourly observations

Two closely related methods to obtain estimates of the hourly peak wind at Cape Kennedy were compared by statistical tests. The methods evaluated the Monin-Obukhov stability length and the standard deviation of the hourly observed wind speed, so as to augment the latter quantity by F standard deviations. F is an optimized factor. A third method utilizing an optimized gust factor was also applied to the hourly wind. The latter procedure estimated 2952 peak winds with an rms error of 2.81 knots, an accuracy which was not surpassed by the other methods. Peak ground wind speed data were developed for use in space shuttle design operation analyses

Study of the technique of stellar occultation

The results are reported of a study of the stellar occultation technique for measuring the composition of the atmosphere. The intensity of starlight was monitored during the occultation using the Wisconsin stellar ultraviolet photometers aboard the Orbiting Astronomical Observatory (OAO-A2). A schematic diagram of an occultation is shown where the change in intensity at a given wavelength is illustrated. The vertical projection of the attenuation region is typically 60 km deep for molecular oxygen and 30 km deep for ozone. Intensity profiles obtained during various occultations were analyzed by first determining the tangential columm density of the absorbing gases, and then Abel inverting the column densities to obtain the number density profile. Errors are associated with each step in the inversion scheme and have been considered as an integral part of this study

The tumour microenvironment links complement system dysregulation and hypoxic signalling.

The complement system is an innate immune pathway typically thought of as part of the first line of defence against "non-self" species. In the context of cancer, complement has been described to have an active role in facilitating cancer-associated processes such as increased proliferation, angiogenesis and migration. Several cellular members of the tumour microenvironment express and/or produce complement proteins locally, including tumour cells. Dysregulation of the complement system has been reported in numerous tumours and increased expression of complement activation fragments in cancer patient specimens correlates with poor patient prognosis. Importantly, genetic or pharmacological targeting of complement has been shown to reduce tumour growth in several cancer preclinical models, suggesting that complement could be an attractive therapeutic target. Hypoxia (low oxygen) is frequently found in solid tumours and has a profound biological impact on cellular and non-cellular components of the tumour microenvironment. In this review, we focus on hypoxia since this is a prevailing feature of the tumour microenvironment that, like increased complement, is typically associated with poor prognosis. Furthermore, interesting links between hypoxia and complement have been recently proposed but never collectively reviewed. Here, we explore how hypoxia alters regulation of complement proteins in different cellular components of the tumour microenvironment, as well as the downstream biological consequences of this regulation

Millisecond accuracy video display using OpenGL under Linux

To measure people’s reaction times to the nearest millisecond, it is necessary to know exactly when a stimulus is displayed. This article describes how to display stimuli with millisecond accuracy on a normal CRT monitor, using a PC running Linux. A simple C program is presented to illustrate how this may be done within X Windows using the OpenGL rendering system. A test of this system is reported that demonstrates that stimuli may be consistently displayed with millisecond accuracy. An algorithm is presented that allows the exact time of stimulus presentation to be deduced, even if there are relatively large errors in measuring the display time