Multi-Moji: Combining Thermal, Vibrotactile and Visual Stimuli to Expand the Affective Range of Feedback

This paper explores the combination of multiple concurrent modalities for conveying emotional information in HCI: temperature, vibration and abstract visual displays. Each modality has been studied individually, but can only convey a limited range of emotions within two-dimensional valencearousal space. This paper is the first to systematically combine multiple modalities to expand the available affective range. Three studies were conducted: Study 1 measured the emotionality of vibrotactile feedback by itself; Study 2 measured the perceived emotional content of three bimodal combinations: vibrotactile + thermal, vibrotactile + visual and visual + thermal. Study 3 then combined all three modalities. Results show that combining modalities increases the available range of emotional states, particularly in the problematic top-right and bottom-left quadrants of the dimensional model. We also provide a novel lookup resource for designers to identify stimuli to convey a range of emotions

Radioactively driven colloids: A special case of anomalous diffusion

Citation: Wilson, G., Bahadori, A. A., & Bindra, H. (2019). Radioactively driven colloids: A special case of anomalous diffusion. Journal of Applied Physics, 126(12), 124308. https://doi.org/10.1063/1.5116220A novel concept of self-propelled, radioactively driven colloids is introduced. The focus of this paper is on assessing the impact of alpha emissions on colloidal kinematics. Using Langevin dynamics and a random walk model, a theory has been developed to describe this motion. This theory shows a special case of anomalous diffusion. Numerical simulations have substantiated the theory. It is shown that alpha-particle emission can significantly affect the motion of colloidal particles, although a very short-lived radioisotope is required

Textured Surfaces for Ultrasound Haptic Displays

We demonstrate a technique for rendering textured haptic surfaces in mid-air, using an ultrasound haptic display. Our technique renders tessellated 3D `haptic' shapes with different waveform properties, creating surfaces with distinct perceptions

Atypical chemokine receptor ACKR2 controls branching morphogenesis in the developing mammary gland

Macrophages are important regulators of branching morphogenesis during development and postnatally in the mammary gland. Regulation of macrophage dynamics during these processes can therefore have a profound impact on development. We demonstrate here that the developing mammary gland expresses high levels of inflammatory CC-chemokines, which are essential in vivo regulators of macrophage migration. We further demonstrate that the atypical chemokine receptor ACKR2, which scavenges inflammatory CC-chemokines, is differentially expressed during mammary gland development. We have previously shown that ACKR2 regulates macrophage dynamics during lymphatic vessel development. Here, we extend these observations to reveal a novel role for ACKR2 in regulating the postnatal development of the mammary gland. Specifically, we show that Ackr2−/− mice display precocious mammary gland development. This is associated with increased macrophage recruitment to the developing gland and increased density of the ductal epithelial network. These data demonstrate that ACKR2 is an important regulator of branching morphogenesis in diverse biological contexts and provide the first evidence of a role for chemokines and their receptors in postnatal development processes

The relationship between frailty, functional dependence, and healthcare needs among community‐dwelling people with moderate to severe dementia

This paper examines the healthcare needs of community‐dwelling older people living in Porto, Portugal, diagnosed with moderate or severe dementia, linked to functional dependency, cognitive decline, limitations in the activities of daily life, and frailty levels. A sample of 83 participants was recruited. Data were collected between 2013 and 2017. A sociodemographic questionnaire, the Clinical Dementia Rating (CDR), the Barthel Index (BI), the Lawton and Brody Instrumental Activities of Daily Living (IADL) Scale, and the Edmonton Frail Scale (EFS) were used. A set of 26 healthcare needs was defined to support the assessment. The Pearson chi‐square or Fisher’s exact test (as appropriate) was used to examine the association of the needs (unmet and met) with the levels of dementia and frailty. Participants were diagnosed previously with moderate or severe dementia and benefited from a structured home‐care program. There was a high number rated as “severe dementia,” “fully dependent,” “severely or fully dependent in the activities of daily living (ADL),” and “severe frailty.” There were statistically significant differences among needs identified in people with moderate or severe dementia and moderate or severe frailty. The most prevalent healthcare needs in the sample were food preparation, medication/taking pills, looking after their home, toilet use, sensory problems, communication/interaction, bladder, bowels, eating and drinking, memory, sleeping, and falls prevention. In particular, the study identifies a set of needs that are present simultaneously in both frailty and dementia stages. This study underlines that despite well‐structured home‐care programs for people with dementia, unmet health needs remain. Timely healthcare needs assessment may help professionals to avoid fragmented care and to tailor quality‐ integrated interventions, including the emotional and psychological balance of the caregiver.publishe

The VAST Survey - III. The multiplicity of A-type stars within 75 pc

With a combination of adaptive optics imaging and a multi-epoch common proper motion search, we have conducted a large volume-limited (D $\le$ 75 pc) multiplicity survey of A-type stars, sensitive to companions beyond 30 au. The sample for the Volume-limited A-STar (VAST) survey consists of 435 A-type stars: 363 stars were observed with adaptive optics, 228 stars were searched for wide common proper motion companions and 156 stars were measured with both techniques. The projected separation coverage of the VAST survey extends from 30 to 45,000 au. A total of 137 stellar companions were resolved, including 64 new detections from the VAST survey, and the companion star fraction, projected separation distribution and mass ratio distribution were measured. The separation distribution forms a log-normal distribution similar to the solar-type binary distribution, but with a peak shifted to a significantly wider value of 387 (+132,-98) au. Integrating the fit to the distribution over the 30 to 10,000 au observed range, the companion star fraction for A-type stars is estimated as 33.8%+-2.6%. The mass ratio distribution of closer (<125 au) binaries is distinct from that of wider systems, with a flat distribution for close systems and a distribution that tends towards smaller mass ratios for wider binaries. Combining this result with previous spectroscopic surveys of A-type stars gives an estimate of the total companion star fraction of 68.9%+-7.0%. The most complete assessment of higher order multiples was estimated from the 156-star subset of the VAST sample with both adaptive optics and common proper motion measurements, combined with a literature search for companions, yielding a lower limit on the frequency of single, binary, triple, quadruple and quintuple A-type star systems of 56.4 (-4.0,+3.8), 32.1 (-3.5,+3.9), 9.0 (-1.8,+2.8), 1.9 (-0.6,+1.8) and 0.6 (-0.2,+1.4) per cent, respectively.Comment: 46 pages, 24 figures. Accepted for publication in the Monthly Notices of the Royal Astronomical Society, 7th October 201

Increased prevalence of expiratory flow limitation during exercise in children with bronchopulmonary dysplasia.

Evidence regarding the prevalence of expiratory flow limitation (EFL) during exercise and the ventilatory response to exercise in children born preterm is limited. This study aimed to determine the prevalence of EFL as well as contributing factors to EFL and the ventilatory response to exercise in preterm children with and without bronchopulmonary dysplasia (BPD). Preterm children (=32 weeks gestational age) aged 9-12 years with (n=64) and without (n=42) BPD and term controls (n=43), performed an incremental treadmill exercise test with exercise tidal flow-volume loops. More preterm children with BPD (53%) had EFL compared with preterm children without BPD (26%) or term controls (28%) (p&lt;0.05). The presence of EFL was independently associated with decreased forced expiratory volume in 1 s/forced vital capacity z-score and lower gestational age (p&lt;0.05). There was no difference in peak oxygen uptake between preterm children with BPD and term controls (48.0 versus 48.4 mL·kg-1·min-1; p=0.063); however, children with BPD had a lower tidal volume at peak exercise (mean difference -27 mL·kg-1, 95% CI -49-?-5; p&lt;0.05). Children born preterm without BPD had ventilatory responses to exercise similar to term controls. Expiratory flow limitation is more prevalent in children born preterm with BPD and is associated with airway obstruction and a lower gestational age

Prenatal development is linked to bronchial reactivity: epidemiological and animal model evidence

Chronic cardiorespiratory disease is associated with low birthweight suggesting the importance of the developmental environment. Prenatal factors affecting fetal growth are believed important, but the underlying mechanisms are unknown. The influence of developmental programming on bronchial hyperreactivity is investigated in an animal model and evidence for comparable associations is sought in humans. Pregnant Wistar rats were fed either control or protein-restricted diets throughout pregnancy. Bronchoconstrictor responses were recorded from offspring bronchial segments. Morphometric analysis of paraffin-embedded lung sections was conducted. In a human mother-child cohort ultrasound measurements of fetal growth were related to bronchial hyperreactivity, measured at age six years using methacholine. Protein-restricted rats' offspring demonstrated greater bronchoconstriction than controls. Airway structure was not altered. Children with lesser abdominal circumference growth during 11-19 weeks' gestation had greater bronchial hyperreactivity than those with more rapid abdominal growth. Imbalanced maternal nutrition during pregnancy results in offspring bronchial hyperreactivity. Prenatal environmental influences might play a comparable role in humans

Using step width to compare locomotor biomechanics between extinct, non-avian theropod dinosaurs and modern obligate bipeds

How extinct, non-avian theropod dinosaurs locomoted is a subject of considerable interest, as is the manner in which it evolved on the line leading to birds. Fossil footprints provide the most direct evidence for answering these questions. In this study, step width—the mediolateral (transverse) distance between successive footfalls—was investigated with respect to speed (stride length) in non-avian theropod trackways of Late Triassic age. Comparable kinematic data were also collected for humans and 11 species of ground-dwelling birds. Permutation tests of the slope on a plot of step width against stride length showed that step width decreased continuously with increasing speed in the extinct theropods (p < 0.001), as well as the five tallest bird species studied (p < 0.01). Humans, by contrast, showed an abrupt decrease in step width at the walk–run transition. In the modern bipeds, these patterns reflect the use of either a discontinuous locomotor repertoire, characterized by distinct gaits (humans), or a continuous locomotor repertoire, where walking smoothly transitions into running (birds). The non-avian theropods are consequently inferred to have had a continuous locomotor repertoire, possibly including grounded running. Thus, features that characterize avian terrestrial locomotion had begun to evolve early in theropod history

An experimental investigation into DEF dosing strategies for heavy duty vehicle applications

Copyright © 2015 SAE International.In recent years urea selective catalytic reduction (SCR) has become the principal method of NOx abatement within heavy duty (HD) diesel exhaust systems; however, with upcoming applications demanding NOx reduction efficiencies of above 96 % on engines producing upwards of 10 g·kWh−1 NOx, future diesel exhaust fluid (DEF) dosing systems will be required to operate stably at significantly increased dosing rates. Developing a dosing system capable of meeting the increased performance requirements demands an improved understanding of how DEF sprays interact with changing exhaust flows. This study has investigated four production systems representing a diverse range of dosing strategies in order to determine how performance is influenced by spray structure and identify promising strategies for further development. The construction of an optically accessible hot-air flow rig has enabled visualisation of DEF injection into flows representative of HD diesel exhaust conditions. High-speed and laser sheet imaging have been applied to capture the injection event and analyse spray development within the flows. Results from ambient shadowgraphy show the extent of variation in spray structure that exists between the systems; further quantified with droplet size distribution data collected using phase Doppler interferometry (PDI). Imaging within the exhaust section indicates that the structure of a spray has a significant impact on droplet entrainment within the flow, in turn affecting the level of spray-wall impingement seen. This suggests knowledge of dosing strategy will be critical for optimal system design and enabling near future dosing rate demands to be met