Transition metal decorated soft nanomaterials through modular self-assembly of an asymmetric hybrid polyoxometalate

An asymmetrically functionalised Wells–Dawson organic–inorganic hybrid polyoxometalate has been post-functionalised by Pt2+ coordination, and demonstrates self-assembly into surface-decorated micellar nanostructures. This multifunctional hybrid material is found to be a redox-active soft nanomaterial and demonstrates a new molecular design strategy with potential for applications in photo- or electro-catalysis

Mexican Banking Regulation: Evidence of the Appropriateness of Government Intervention

In this paper we investigate the validity of two assumptions frequently used to justify the transformation of the Mexican banking system through federal regulation. These assumptions are: (i) the alleged existence of economies of scale, and (ii) a homogeneous structure of the Mexican banking system. Econometric evidence from banking data over the period 1980 - 1982 suggests that neither of these assumptions are likely valid. The Mexican banking system is subject to constant rather than increasing returns to scale

Practitioner Feedback on Lung Cancer Practice Guidelines in Ontario

Purpose:Practitioner feedback (PF) surveys are sent to practitioners who care for lung cancer patients as each new practice guideline is completed. In this study, the PF was reviewed to assess the frequency of response to the surveys, the respondents’ characteristics, the nature of the feedback, and the intention to adopt the guideline in practice.Methods:Fourteen practice guidelines (PGs) were sent to Ontario practitioners treating lung cancer, and feedback on the PGs was obtained through either an eight- or 21-item survey.Results:Between 1995 and 2002, 1198 surveys were sent to 223 practitioners. The overall response rate was 58.9% but varied by specialty (radiation and medical oncologists, 67%; thoracic surgeons, 46%; respirologists, 38%), by location of practice (cancer center, 65%; community-based practice, 55%), by geographic region of the province (highest, 72%; lowest, 42%), and by PG topic (chemotherapy, 60%; radiotherapy, 63%; combined modality therapy, 52%). The response rate to the PF surveys did not decline over time. Eighty-six percent of respondents agreed with the lung cancer guidelines and indicated that they were likely or very likely to use the PGs in their practice.Conclusion:The results suggest that practitioners view the guideline development process as credible and useful to guide practice. Whether the stated intention to use the guidelines will actually translate into practice requires further study

Transport of magnetic flux from the canopy to the internetwork

Recent observations have revealed that 8% of linear polarization patches in the internetwork quiet Sun are fully embedded in downflows. These are not easily explained with the typical scenarios for the source of internetwork fields which rely on flux emergence from below. We explore using radiative MHD simulations a scenario where magnetic flux is transported from the magnetic canopy overlying the internetwork into the photosphere by means of downward plumes associated with convective overshoot. We find that if a canopy-like magnetic field is present in the simulation, the transport of flux from the canopy is an important process for seeding the photospheric layers of the internetwork with magnetic field. We propose that this mechanism is relevant for the Sun as well, and it could naturally explain the observed internetwork linear polarization patches entirely embedded in downflows.Comment: Accepted to Ap

Management Information Systems Education: A Systematic Review

Management information systems (MIS) programs were developed to prepare graduates to create innovative solutions to problems where business and technology intersect. As such, the curricula must change rapidly to stay current with industry standards, an accelerating moving target. This research presents the findings of a systematic literature review to identify and present trends in the scholarly literature on MIS education. The purpose of this approach was to understand how academia ensures students are prepared for industry and keeps pace with changing industry needs. Key findings from the literature are presented, as well as a compilation of areas for future research. Overwhelmingly, a lack of international perspective was identified as the vast majority of articles collected data in the US. Further, the direction of future research and exploration revolved around five themes of innovative pedagogical approaches, industry partnerships, subtopics of MIS education, new methods and metrics for measuring success in MIS education, and cross-disciplinary opportunities in fields such as mathematics, traditional business disciplines, and the hard sciences

Transcription Factor Competition Allows Embryonic Stem Cells to Distinguish Authentic Signals from Noise

Stem cells occupy variable environments where they must distinguish stochastic fluctuations from developmental cues. Here, we use optogenetics to investigate how the pluripotency network in embryonic stem cells (ESCs) achieves a robust response to differentiation cues but not to gene expression fluctuations. We engineered mouse ESCs to allow quantitative control over the endogenous mechanism of neural differentiation through a light-inducible Brn2 transgene and monitored differentiation status through a genome-integrated Nanog-GFP reporter. By exposing cells to pulses of Brn2, we find that the pluripotency network rejects Brn2 inputs that are below specific magnitude or duration thresholds, but allows rapid differentiation when both thresholds are satisfied. The filtering properties of the network arise through its positive feedback architecture and the intrinsic half-life of Nanog, which determines the duration threshold in the network. Together our results suggest that the dynamic properties of positive feedback networks might determine how inputs are classified as signal or noise by stem cells

Education in Process Systems Engineering: Why it matters more than ever and how it can be structured

This position paper is an outcome of discussions that took place at the third FIPSE Symposium in Rhodes, Greece, between June 20–22, 2016 (http://fi-in-pse.org). The FIPSE objective is to discuss open research challenges in topics of Process Systems Engineering (PSE). Here, we discuss the societal and industrial context in which systems thinking and Process Systems Engineering provide indispensable skills and tools for generating innovative solutions to complex problems. We further highlight the present and future challenges that require systems approaches and tools to address not only ‘grand’ challenges but any complex socio-technical challenge. The current state of Process Systems Engineering (PSE) education in the area of chemical and biochemical engineering is considered. We discuss approaches and content at both the unit learning level and at the curriculum level that will enhance the graduates’ capabilities to meet the future challenges they will be facing. PSE principles are important in their own right, but importantly they provide significant opportunities to aid the integration of learning in the basic and engineering sciences across the whole curriculum. This fact is crucial in curriculum design and implementation, such that our graduates benefit to the maximum extent from their learning

Decay of a simulated mixed-polarity magnetic field in the solar surface layers

Magnetic flux is continuously being removed and replenished on the solar surface. To understand the removal process we carried out 3D radiative MHD simulations of the evolution of patches of photospheric magnetic field with equal amounts of positive and negative flux. We find that the flux is removed at a rate corresponding to an effective turbulent diffusivity, of 100--340 km^2/s, depending on the boundary conditions. For average unsigned flux densities above about 70 Gauss, the percentage of surface magnetic energy coming from different field strengths is almost invariant. The overall process is then one where magnetic elements are advected by the horizontal granular motions and occasionally come into contact with opposite-polarity elements. These reconnect above the photosphere on a comparatively short time scale after which the U loops produced rapidly escape through the upper surface while the downward retraction of inverse-U loops is significantly slower, because of the higher inertia and lower plasma beta in the deeper layers.Comment: 8 pages, 10 figures accepted in A&

The bright galaxy population of five medium redshift clusters. II. Quantitative Galaxy Morphology

Aims: Following the study already presented in our previous paper, based on the Nordic Optical Telescope (NOT) sample, which consists of five clusters of galaxies within the redshift range 0.18 $\leq$ z $\leq$ 0.25, imaged in the central 0.5-2 Mpc in very good seeing conditions, we have studied the quantitative morphology of their bright galaxy population Methods: We have analyzed the surface brightness profiles of the galaxy population in those clusters. Previously, we have performed simulations in order to check the reliability of the fits. We have also derived a quantitative morphological classification. Results: The structural parameters derived from these analysis have been analyzed. We have obtained that the structural parameters of E/S0 galaxies are similar to those showed by galaxies in low redshift clusters. However, the disc scales are different. In particular, the scales of the discs of galaxies at medium redshift clusters are statistically different than those located in similar galaxies in the Coma cluster. But, the scales of the discs of galaxies in medium redshift clusters are similar to nearby field galaxies. Conclusions: The results suggest that the evolution of the disc component of galaxies in clusters is faster than in field ones. Mechanisms like galaxy harassment showing timescales of $\sim 1$Gyr could be the responsible of this disc scale evolution. This indicates that spiral galaxies in clusters have suffered a strong evolution in the last 2.5 Gyr or that Coma is in some way anomalous.Comment: 13 pages, 10 figures, Accepted for publication in A&