Genomic Characterization of the Taylorella Genus

The Taylorella genus comprises two species: Taylorella equigenitalis, which causes contagious equine metritis, and Taylorella asinigenitalis, a closely-related species mainly found in donkeys. We herein report on the first genome sequence of T. asinigenitalis, analyzing and comparing it with the recently-sequenced T. equigenitalis genome. The T. asinigenitalis genome contains a single circular chromosome of 1,638,559 bp with a 38.3% GC content and 1,534 coding sequences (CDS). While 212 CDSs were T. asinigenitalis-specific, 1,322 had orthologs in T. equigenitalis. Two hundred and thirty-four T. equigenitalis CDSs had no orthologs in T. asinigenitalis. Analysis of the basic nutrition metabolism of both Taylorella species showed that malate, glutamate and alpha-ketoglutarate may be their main carbon and energy sources. For both species, we identified four different secretion systems and several proteins potentially involved in binding and colonization of host cells, suggesting a strong potential for interaction with their host. T. equigenitalis seems better-equipped than T. asinigenitalis in terms of virulence since we identified numerous proteins potentially involved in pathogenicity, including hemagluttinin-related proteins, a type IV secretion system, TonB-dependent lactoferrin and transferrin receptors, and YadA and Hep_Hag domains containing proteins. This is the first molecular characterization of Taylorella genus members, and the first molecular identification of factors potentially involved in T. asinigenitalis and T. equigenitalis pathogenicity and host colonization. This study facilitates a genetic understanding of growth phenotypes, animal host preference and pathogenic capacity, paving the way for future functional investigations into this largely unknown genus

Etienne Balibar, La Philosophie de Marx

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Situation de la déconstruction: De la « promesse d’or » à l’inconvertibilité

Derrida’s philosophy is first of all about sign, writing, text, but it also leads to economy through the notion of « différance » and through the structural homologies between language and money. Homologies which are inherent to Saussure’s analysis of value in linguistic. More generally, the relationship between the discourse and reality could be metaphorized by the operation of convertibility of conventional monetary signs to an available gold treasure. Nevertheless, this « promise of gold » (Bergson) belongs to an era which is no longer ours, in the present regime of inconvertibility. The main thesis of this article is that Derrida’s deconstruction situates itself in a precise historical moment, between the promise of convertibility (where gold is the typical value, available somewhere) and the venue of inconvertibility, a regime in which the sign, either monetary or linguistic, refers to other signs, in an indefinite play, without garanted and stable value or « transcendantal signified ». Then, the era of deconstruction could be linked to an era of economy which can be itself enlightened in return by the various concepts related to deconstruction

Marx y la inscripcion del trabajo

De manera privilegiada, y a menudo exclusiva, el lenguaje es concebido (en la historia occidental) como un conjunto de signos de cambio, Ya sea bajo e1 aspecto comunicativo, expresivo, o incluso más sutilmente, dentro de la opción del criterio de traductibilidad como característico de todo lenguaje, se alude siempre al signo considerado como uno de los elementos de una transacción comercial. De modo unánime (de Aristóteles a Martinet) el acento se ha colocado sobre el valor de cambio de los signos -sobre su función dentro del proceso de circulación-

Les iconoclastes /

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