Light Assisted Collisional Loss in a 85/87^{85/87}Rb Ultracold Optical Trap

We have studied hetero- and homonuclear excited state/ground state collisions by loading both $^{85}$Rb and $^{87}$Rb into a far off resonant trap (FORT). Because of the relatively weak confinement of the FORT, we expect the hyperfine structure of the different isotopes to play a crucial role in the collision rates. This dependence on hyperfine structure allows us to measure collisions associated with long range interatomic potentials of different structure: such as long and short ranged; or such as purely attractive, purely repulsive, or mixed attractive and repulsive. We observe significantly different loss rates for different excited state potentials. Additionally, we observe that some collisional channels' loss rates are saturated at our operating intensities (~15 mW/cm$^{2}$). These losses are important limitations in loading dual isotope optical traps.Comment: about 8 pages, 5 figure

A versatile microarray platform for capturing rare cells

Analyses of rare events occurring at extremely low frequencies in body fluids are still challenging. We established a versatile microarray-based platform able to capture single target cells from large background populations. As use case we chose the challenging application of detecting circulating tumor cells (CTCs) - about one cell in a billion normal blood cells. After incubation with an antibody cocktail, targeted cells are extracted on a microarray in a microfluidic chip. The accessibility of our platform allows for subsequent recovery of targets for further analysis. The microarray facilitates exclusion of false positive capture events by co-localization allowing for detection without fluorescent labelling. Analyzing blood samples from cancer patients with our platform reached and partly outreached gold standard performance, demonstrating feasibility for clinical application. Clinical researchers free choice of antibody cocktail without need for altered chip manufacturing or incubation protocol, allows virtual arbitrary targeting of capture species and therefore wide spread applications in biomedical sciences

On Meme Self-Adaptation in Spatially-Structured Multimemetic Algorithms

NMA 2014Multimemetic algorithms (MMAs) are memetic algorithms that explicitly exploit the evolution of memes, i.e., non-genetic expressions of problem-solving strategies. We consider a class of MMAs in which these memes are rewriting rules whose length can be fixed during the run of the algorithm or self-adapt during the search process. We analyze this self-adaptation in the context of spatially-structured MMAs, namely MMAs in which the population is endowed with a certain topology to which interactions (from the point of view of selection and variation operators) are constrained. For the problems considered, it is shown that panmictic (i.e., non-structured) MMAs are more sensitive to this self-adaptation, and that using variable-length memes seems to be a robust strategy throughout different population structures.This work is partially supported by MICINN project ANYSELF (TIN2011-28627-C04-01), by Junta de Andaluía project DNEMESIS (P10-TIC-6083) and by Universidad de Málaga, Campus de Excelencia Internacional Andalucía Tech

Isomer shift and magnetic moment of the long-lived 1/2+^{+} isomer in 3079^{79}_{30}Zn49_{49}: signature of shape coexistence near 78^{78}Ni

Collinear laser spectroscopy has been performed on the $^{79}_{30}$Zn$_{49}$ isotope at ISOLDE-CERN. The existence of a long-lived isomer with a few hundred milliseconds half-life was confirmed, and the nuclear spins and moments of the ground and isomeric states in $^{79}$Zn as well as the isomer shift were measured. From the observed hyperfine structures, spins $I = 9/2$ and $I = 1/2$ are firmly assigned to the ground and isomeric states. The magnetic moment $\mu$ ($^{79}$Zn) = $-$1.1866(10) $\mu_{\rm{N}}$, confirms the spin-parity $9/2^{+}$ with a $\nu g_{9/2}^{-1}$ shell-model configuration, in excellent agreement with the prediction from large scale shell-model theories. The magnetic moment $\mu$ ($^{79m}$Zn) = $-$1.0180(12) $\mu_{\rm{N}}$ supports a positive parity for the isomer, with a wave function dominated by a 2h-1p neutron excitation across the $N = 50$ shell gap. The large isomer shift reveals an increase of the intruder isomer mean square charge radius with respect to that of the ground state: $\delta \langle r^{2}_{c}\rangle^{79,79m}$ = +0.204(6) fm$^{2}$, providing first evidence of shape coexistence.Comment: 5 pages, 4 figures, 1 table, Accepeted by Phys. Rev. Lett. (2016