Especificacion de requerimientos para un sitio web de intermediacion laboral para tecnicos - profesionales de la Region del Maule

110 p.El Programa Chile Califica desarrolla instrumentos para facilitar la educación y capacitación permanente, preocupándose por lograr la inserción en el mercado laboral de los jóvenes que terminan su ciclo formal de enseñanza técnico profesional. Los actuales sistemas de intermediación laboral a nivel público en la Región del Maule no logran hacer un vínculo efectivo entre empresarios y fuerza de trabajo en términos de qué es lo que buscan, por motivo de no tener información oportuna, válida y completa. Está entonces la necesidad de tener un sistema de intermediación laboral, basado en Internet, que logre conectar a oferta y demanda de trabajo efectivamente, y para esto es necesario conocer las características que debería tener este sistema de información. Dado lo anterior, el objetivo de este estudio es determinar los servicios requeridos por los potenciales usuarios de un sitio Web de intermediación laboral orientado a técnico profesionales de la Región del Maule. Para lograr esto, se plantean como objetivos específicos el analizar el dominio del entorno de desarrollo del proyecto, el obtener la especificación de los requerimientos para un sitio Web de este tipo, y el lograr que la especificación de requerimientos del sitio Web contenga lo necesario para que el sistema pueda cumplir con su propósito. Para cumplir con estos objetivos se ejecuta el proceso de ingeniería de requerimientos. Durante este proceso se analizan datos estadísticos y se realizan entrevistas en una etapa preliminar. Se aplica un muestreo no probabilística por conveniencia en la realización de reuniones de grupo de las que se obtienen los requerimientos para el sitio Web, los que son organizados, estudiados y revisados, para luego poder especificarlos y llevarlos a un documento. De lo anterior se obtienen las especificaciones de los requerimientos que determinan claramente los servicios que debería prestar un sitio Web de intermediación laboral. Al hacer un análisis del estudio se puede observar que el problema de fondo es que la información relacionada con mercado laboral proviene de diversas fuentes que están dispersas, por lo que surge la necesidad de un sistema de información que permita la integración de ellas en una única plataforma, de modo que la intermediación laboral sea uno de sus componentes. El interés despertado en los potenciales usuarios del sitio Web propuesto amerita su avance a la etapa de diseño del mismo para su pronta implementación

Expressão de SPLUNC1 (BPIFA1) e SPLUNC2A (BPIFA2A) na saliva de pacientes submetidos à radioterapia

Orientador: Márcio Ajudarte LopesTese (doutorado) - Universidade Estadual de Campinas, Faculdade de Odontologia de PiracicabaResumo: A radioterapia causa alterações na composição salivar e as proteínas PLUNC participam na resposta imune inata da cavidade oral. O objetivo desse estudo foi verificar se a radioterapia é capaz de modificar a expressão de PLUNC salivar e se essas proteínas estão associadas com os efeitos colaterais. MATERIAIS E MÉTODOS: Foi coletada saliva não estimulada de 65 voluntários (45 pacientes com câncer e 20 controles). No grupo de estudo a coleta foi realizada uma semana antes do início da radioterapia, no meio do tratamento e uma semana após o término. A expressão de SPLUNC1 e SPLUNC2A foi detectada por western blot, e foi analisada com os dados clínico-patológicos e efeitos colaterais. RESULTADOS: Foi notada uma redução do fluxo salivar durante e após o término da radioterapia, sendo mais acentuada nos pacientes que foram submetidos a radioterapia envolvendo a região facial. O campo de radiação facial foi correlacionado com os efeitos colaterais, principalmente com a presença (p=0,0110) e intensidade (p=0,0143) de mucosite. SPLUNC1 e SPLUNC2A foram detectadas na saliva dos pacientes sem tratamento em concentrações variáveis. O grupo de estudo mostrou níveis de SPLUNC2A significantemente maiores que o grupo controle, enquanto SPLUNC1 não mostrou diferenças. A concentração de PLUNC foi modificada pela radioterapia, observando diminuição dos níveis de SPLUNC2A na sua forma glicosilada (p<,0001) e aumento dos níveis de SPLUNC1 (p=0,0081) na segunda e terceira coletas. A única associação entre efeitos colaterais da radioterapia e PLUNC foi a presença (p=0,0363) e intensidade (p=0,0500) da mucosite com maiores níveis SPLUNC1. CONCLUSÕES: O presente estudo reportou que os níveis de SPLUNC1 e SPLUNC2A glicosilada são afetados pela radioterapia, sugerindo que essas proteínas podem ter importância no microambiente oral dos pacientes irradiados na cabeça e pescoçoAbstract: Radiotherapy causes alteration in saliva composition and PLUNC proteins participate in innate immunity of the oral cavity. The aim of this study was to verify if radiotherapy is able to modify the salivary PLUNC expression and if they are associated with radiotherapy side-effects. MATERIALS AND METHODS: Unstimulated whole-mouth saliva of 65 voluntaries (45 cancer patients and 20 controls) was collected. In the study group the collection was performed one week before the beginning of radiotherapy, in the middle of the treatment and one week after finishing. SPLUNC1 and SPLUNC2A expression were detected by western blotting and was analyzed with clinicopathological data and radiotherapy side-effects. RESULTS: Reduction of salivary flow rates was observed during and after conclusion of radiotherapy, being more accentuated in patients who underwent radiotherapy involving the facial region. Facial radiation field was correlated with collateral effects, mainly with the presence (p=0.0110) and severity (p=0.0143) of mucositis. SPLUNC1 and SPLUNC2A were detected in saliva of patients without treatment in variable concentrations. The study group showed levels of SPLUNC2A significantly higher than the control group, while SPLUNC1 did not show differences. Concentration of PLUNC was modified by radiotherapy, observing decreasing of glycosilated form of SPLUNC2A levels (p<.0001) and increasing of SPLUNC1 levels (p=0.0081) in the second and third collections. The only association between collateral effects of radiotherapy and PLUNC was the presence of mucositis (p=0.0363) and its severity (p=0.0500) with higher levels of SPLUNC1. CONCLUSIONS: The present study reported that levels of SPLUNC1 and glycosilated SPLUNC2A are affected by the radiotherapy, suggesting that these proteins may have importance in the oral microenvironment of irradiated head and neck cancer patientsDoutoradoEstomatologiaDoutor em Estomatopatologi

Study of the immunohistochemical expression of Plunc family proteins in mucoepidermoid carcinomas of the salivary glands

Orientadores: Márcio Ajudarte Lopes, Alan Roger dos Santos SilvaDissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de PiracicabaResumo: Tumores de glândulas salivares são raros e geralmente apresentam características histopatológicas complexas que podem dificultar seu diagnóstico. O carcinoma mucoepidermóide (CME) é a neoplasia maligna mais frequente das glândulas salivares e é classificado histologicamente como de baixo grau, grau intermediário ou de alto grau. O uso de técnicas histoquímicas como o PAS (Periodic Acid-Schiff) ou o mucicarmin é de grande utilidade para identificar mucina nos tumores e permitir o diagnóstico do CME. Recentemente, descreveu-se que alguns tumores de glândulas salivares como o cistoadenocarcinoma papilar e o CME expressam proteínas da família PLUNC. O objetivo deste estudo foi avaliar a expressão imunoistoquímica das proteínas da família PLUNC em 30 casos de CMEs de glândulas salivares maiores e menores e testar a hipótese de que estas proteínas poderiam ser úteis no diagnóstico do CME. Os tumores foram revisados e classificados de acordo com o grau de malignidade e estudados por meio de reações histoquímicas (sendo todos os casos positivos para PAS e mucicarmin) e imunoistoquímicas para as proteínas SPLUNC1, LPLUNC1, SPLUNC2A, SPLUNC2B e LPLUNC2. A média de idade dos pacientes diagnosticados com CME foi de 44,07 anos. A maioria dos tumores (19) foi classificada como de baixo grau, 4 tumores foram classificados como grau intermediário e 7 como alto grau. A marcação imunoistoquímica foi classificada de acordo com a quantidade e intensidade de células marcadas no tumor. A maioria dos CMEs estudados foi positiva para SPLUNC1 (90%) e LPLUNC1 (93,33%), sendo identificada principalmente em células mucosas, plugs de mucina e células intermediárias. SPLUNC2A, SPLUNC2B e LPLUNC2 foram negativos na maioria dos tumores. LPLUNC2 apresentou positividade em células semelhantes a mastócitos em 83,33% dos tumores, expressão parece não ter sido relatada previamente na literatura. A expressão de SPLUNC1 e LPLUNC1 apresentou um padrão de marcação semelhante ao identificado com PAS e mucicarmin. A positividade para SPLUNC1 e LPLUNC1 nas células intermediárias, sugere que estas duas proteínas poderiam ser úteis no diagnóstico de casos de CME de alto grau de malignidadeAbstract: Salivary gland tumours are uncommon and generally present complex histopathologic features that can difficult the diagnosis. Mucoepidermoid carcinomas (MECs) are the most frequent malignant neoplasia of the salivary glands and are histologically classified as low, intermediate and high-grade. Histochemical stains such as PAS (Periodic Acid-Schiff) or mucicarmine are very useful to indentify mucine in tumors and to make the diagnosis of MEC. Recently, the expression of PLUNC family proteins has been described in salivary glands tumors, such as papillary cystoadenocarcinoma and MEC, suggesting that these proteins can be useful for the diagnosis in some difficult cases. The aim of this study was to evaluate the expression of PLUNC family proteins in 30 cases of MEC of the salivary glands and test the hypothesis that these proteins could be useful in the diagnosis of MEC. The tumors were reviewed and classified according to the grade of malignancy. Histochemical stains (PAS and mucicarmine) and immunohistochemical reactions for SPLUNC1, LPLUNC1, SPLUNC2A, SPLUNC2B and LPLUNC2 were performed. Patient's mean age was 44.07 years old. The majority of tumors (19) was histologically classified as low grade, 4 tumors were intermediate grade and 7 were high grade. All cases were positive for PAS and mucicarmine. Immunohistochemical stain was classified according to the quantity and intensity of stained cells in the tumor. Most of the MECs were positive for SPLUNC1 (90%) and LPLUNC1 (93.33%), particularly in mucous cells, mucin plugs and intermediary cells. SPLUNC2A, SPLUNC2B and LPLUNC2 did not present significant expression in the tumors. LPLUNC2 presented positivity for cells that remember mast cells in 83.33% of the tumors, expression that seems not to be previously reported in the literature. The expression pattern of SPLUNC1 and LPLUNC1 was similar to PAS and mucicarmine. The expression in intermediary cells for SPLUNC1 and LPLUNC1, suggest that these proteins could be useful in the diagnosis of high grade MECsMestradoEstomatologiaMestre em Estomatopatologi

The Giraffe Inner Bulge Survey (GIBS) II. Metallicity distributions and alpha element abundances at fixed Galactic latitude

High resolution (R$\sim$22,500) spectra for 400 red clump giants, in four fields within $\rm -4.8^{\circ} \lesssim b \lesssim -3.4^{\circ}$ and $\rm -10^{\circ} \lesssim l \lesssim +10^{\circ}$, were obtained within the GIRAFFE Inner Bulge Survey (GIBS) project. To this sample we added another $\sim$ 400 stars in Baade's Window, observed with the identical instrumental configuration. We constructed the metallicity distributions for the entire sample, as well as for each field individually, in order to investigate the presence of gradients or field-to-field variations in the shape of the distributions. The metallicity distributions in the five fields are consistent with being drawn from a single parent population, indicating the absence of a gradient along the major axis of the Galactic bar. The global metallicity distribution is well fitted by two Gaussians. The metal poor component is rather broad, with a mean at $\rm =-0.31$ dex and $\sigma=0.31$ dex. The metal-rich one is narrower, with mean $\rm =+0.26$ and $\sigma=0.2$ dex. The [Mg/Fe] ratio follows a tight trend with [Fe/H], with enhancement with respect to solar in the metal-poor regime, similar to the one observed for giant stars in the local thick disc. [Ca/Fe] abundances follow a similar trend, but with a considerably larger scatter than [Mg/Fe]. A decrease in [Mg/Fe] is observed at $\rm [Fe/H]=-0.44$ dex. This \textit{knee} is in agreement with our previous bulge study of K-giants along the minor axis, but is 0.1 dex lower in metallicity than the one reported for the Bulge micro lensed dwarf and sub-giant stars. We found no variation in $\alpha$-element abundance distributions between different fields.Comment: Accepted for publication in A&

Clinicopathological And Immunohistochemical Evaluation Of Oral And Oropharyngeal Squamous Cell Carcinoma In Chilean Population

In oral and oropharyngeal squamous cell carcinoma (OCSCC and OPSCC) exist an association between clinical and histopathological parameters with cell proliferation, basal lamina, connective tissue degradation and surrounding stroma markers. We evaluated these associations in Chilean patients. A convenience sample of 37 cases of OCSCC (n=16) and OPSCC (n=21) was analyzed clinically (TNM, clinical stage) and histologically (WHO grade of differentiation, pattern of tumor invasion). We assessed the expression of p53, Ki67, HOXA1, HOXB7, type IV collagen (ColIV) and carcinoma-associated fibroblast (a-SMA-positive cells). Additionally we conducted a univariate/bivariate analysis to assess the relationship of these variables with survival rates. Males were mostly affected (56.2% OCSCC, 76.2% OPSCC). Patients were mainly diagnosed at III/IV clinical stages (68.8% OCSCC, 90.5% OPSCC) with a predominantly infiltrative pattern invasion (62.9% OCSCC, 57.1% OPSCC). Significant association between regional lymph nodes (N) and clinical stage with OCSCC-HOXB7 expression (Chi-Square test P < 0.05) was observed. In OPSCC a statistically significant association exists between p53, Ki67 with gender (Chi-Square test P < 0.05). In OCSCC and OPSCC was statistically significant association between ki67 with HOXA1, HOXB7, and between these last two antigens (Pearson's Correlation test P < 0.05). Furthermore OPSCC-p53 showed significant correlation when it was compared with a-SMA (Kendall's Tau-c test P < 0.05). Only OCSCC-pattern invasion and OPSCC-primary tumor (T) pattern resulted associated with survival at the end of the follow up period (Chi-Square Likelihood Ratio, P < 0.05). Clinical, histological and immunohistochemical features are similar to seen in other countries. Cancer proliferation markers were associated strongly from each other. Our sample highlights prognostic value of T and pattern of invasion, but the conclusions may be limited and should be considered with caution (small sample). Many cases were diagnosed in the advanced stages of the disease, which suggests that the diagnosis of OCSCC and OPSCC is made late.7959685977Wang, Q., Gao, P., Wang, X., Duan, Y., Investigation and identification of potential biomarkers in human saliva for the early diagnosis of oral squamous cell carcinoma (2013) Clin Chim Acta, 427 C, pp. 79-85Parkin, D., Bray, F., Ferlay, J., Pisani, P., Global cancer statistics, 2002 (2005) CA Cancer J Clin, 55, p. 74Dissanayaka, W.L., Pitiyage, G., Kumarasiri, P.V., Liyanage, R.L., Dias, K.D., Tilakaratne, W.M., Clinical and histopathologic parameters in survival of oral squamous cell carcinoma (2012) Oral Surg Oral Med Oral Pathol Oral Radiol, 113, pp. 518-525Koontongkaew, S., The tumor microenvironment contribution to development, growth, invasion and metastasis of head and neck squamous cell carcinomas (2013) J Cancer, 4, p. 66Dalianis, T., Human papillomavirus and oropharyngeal cancer, the epidemics, and significance of additional clinical biomarkers for prediction of response to therapy (2014) Int J Oncol, 44, pp. 1799-1805Kostareli, E., Holzinger, D., Hess, J., New concepts for translational head and neck oncology: Lessons from HPV-related oropharyngeal squamous cell carcinomas (2012) Front Oncol, 2, p. 36Rivera, C., Venegas, B., Histological and molecular aspects of oral squamous cell carcinoma (2014) Oncol Lett, 8, pp. 7-11Bryne, M., Koppang, H.S., Lilleng, R., Kjærheim, Å., Malignancy grading of the deep invasive margins of oral squamous cell carcinomas has high prognostic value (2005) J Pathol, 166, pp. 375-381Santos-Garcia, A., Abad-Hernandez, M.M., Fonseca-Sanchez, E., Julian-Gonzalez, R., Galindo-Villardon, P., Cruz-Hernandez, J.J., Bullon-Sopelana, A., E-cadherin, laminin and collagen IV expression in the evolution from dysplasia to oral squamous cell carcinoma (2006) Med Oral Patol Oral Cir Bucal, 11, pp. E100-E105Ramqvist, T., Dalianis, T., Oropharyngeal cancer epidemic and human papillomavirus (2010) Emerg Infect Dis, 16, pp. 1671-1677Rodrigues, P.C., Miguel, M.C., Bagordakis, E., Fonseca, F.P., de Aquino, S.N., Santos-Silva, A.R., Lopes, M.A., Coletta, R.D., Clinicopathological prognostic factors of oral tongue squamous cell carcinoma: a retrospective study of 202 cases (2014) Int J Oral Maxillofac Surg, 43, pp. 795-801Agarwal, A., Sethi, A., Sareen, D., Dhingra, S., Oral and oropharyngeal squamous cell carcinoma in our population: the clinic-pathological and morphological description of 153 casescarcinoma de Células Escamosas Oral y Orofaríngeo en Nuestra Población: Descripción Clínico-Patológica y Morfológica de 153 Casos (2011) Int J Morphol, 29, pp. 686-693Roosli, C., Tschudi, D.C., Studer, G., Braun, J., Stoeckli, S.J., Outcome of patients after treatment for a squamous cell carcinoma of the oropharynx (2009) Laryngoscope, 119, pp. 534-540Riera, P., Martinez, B., [Morbidity and mortality for oral and pharyngeal cancer in Chile] (2005) Rev Med Chil, 133, pp. 555-563Marsh, D., Suchak, K., Moutasim, K.A., Vallath, S., Hopper, C., Jerjes, W., Upile, T., Thomas, G.J., Stromal features are predictive of disease mortality in oral cancer patients (2011) J Pathol, 223, pp. 470-481Woolgar, J., Rogers, S., West, C., Errington, R., Brown, J., Vaughan, E., Survival and patterns of recurrence in 200 oral cancer patients treated by radical surgery and neck dissection (1999) Oral Oncol, 35, pp. 257-265Bórquez, P., Capdeville, F., Madrid, A., Veloso, M., Cárcamo, M., Sobrevida global y por estadios de 137 pacientes con cáncer intraoral: experiencia del Instituto Nacional del CáncerAnalysis of survival of 137 patients with oral cancer (2011) Rev Chil Cir, 63, pp. 351-355Woolgar, J.A., Triantafyllou, A., Pitfalls and procedures in the histopathological diagnosis of oral and oropharyngeal squamous cell carcinoma and a review of the role of pathology in prognosis (2009) Oral Oncol, 45, pp. 361-385Li, Y., Bai, S., Carroll, W., Dayan, D., Dort, J.C., Heller, K., Jour, G., Brandwein-Gensler, M., Validation of the risk model: high-risk classification and tumor pattern of invasion predict outcome for patients with low-stage oral cavity squamous cell carcinoma (2013) Head Neck Pathol, 7, pp. 211-223Chang, Y.C., Nieh, S., Chen, S.F., Jao, S.W., Lin, Y.L., Fu, E., Invasive pattern grading score designed as an independent prognostic indicator in oral squamous cell carcinoma (2010) Histopathology, 57, pp. 295-303Adeyemi, B.F., Olusanya, A.A., Lawoyin, J.O., Oral squamous cell carcinoma, socioeconomic status and history of exposure to alcohol and tobacco (2011) J Natl Med Assoc, 103, pp. 498-502De Souza Setubal Destro, M.F., Bitu, C.C., Zecchin, K.G., Graner, E., Lopes, M.A., Kowalski, L.P., Coletta, R.D., Overexpression of HOXB7 homeobox gene in oral cancer induces cellular proliferation and is associated with poor prognosis (2010) Int J Oncol, 36, pp. 141-149Bitu, C.C., Destro, M.F., Carrera, M., Da Silva, S.D., Graner, E., Kowalski, L.P., Soares, F.A., Coletta, R.D., HOXA1 is overexpressed in oral squamous cell carcinomas and its expression is correlated with poor prognosis (2012) BMC Cancer, 12, p. 146Liao, W.T., Jiang, D., Yuan, J., Cui, Y.M., Shi, X.W., Chen, C.M., Bian, X.W., Ding, Y.Q., HOXB7 as a prognostic factor and mediator of colorectal cancer progression (2011) Clin Cancer Res, 17, pp. 3569-357

The GIRAFFE Inner Bulge Survey (GIBS). I. Survey Description and a kinematical map of the Milky Way bulge

The Galactic bulge is a massive, old component of the Milky Way. It is known to host a bar, and it has recently been demonstrated to have a pronounced boxy/peanut structure in its outer region. Several independent studies suggest the presence of more than one stellar populations in the bulge, with different origins and a relative fraction changing across the bulge area. This is the first of a series of papers presenting the results of the Giraffe Inner Bulge Survey, carried out at the ESO-VLT with the multifibre spectrograph FLAMES. Spectra of ~5000 red clump giants in 24 bulge fields have been obtained at resolution R=6500, in the infrared Calcium triplet wavelength region at 8500 {\AA}. They are used to derive radial velocities and metallicities, based on new calibration specifically devised for this project. Radial velocities for another ~1200 bulge red clump giants, obtained from similar archive data, have been added to the sample. Higher resolution spectra have been obtained for 450 additional stars at latitude b=-3.5, with the aim of investigating chemical abundance patterns variations with longitude, across the inner bulge. In total we present here radial velocities for 6392 RC stars. We derive a radial velocity, and velocity dispersion map of the Milky Way bulge, useful to be compared with similar maps of external bulges, and to infer the expected velocities and dispersion at any line of sight. The K-type giants kinematics is consistent with the cylindrical rotation pattern of M-giants from the BRAVA survey. Our sample enables to extend this result to latitude b=-2, closer to the Galactic plane than probed by previous surveys. Finally, we find strong evidence for a velocity dispersion peak at (0,-1) and (0,-2), possibly indicative of a high density peak in the central 250 pc of the bulgeComment: A&A in pres

The Adverse Effects of Radiotherapy on the Structure of Dental Hard Tissues and Longevity of Dental Restoration

Purpose: The main goal of this study was to evaluate the impact of different ionizing radiation doses on the mineral (carbonate/phosphate ratio, crystallinity index [CI]) and organic (amide III/phosphate, amide I sub-band ratios) structures, as well as the microhardness, of enamel and dentin, along with their influence on the bonding strength stability of the etch-and-rinse (ER) and self-etch (SE) dental adhesive strategies. Materials and methods: Enamel and dentin human tissue specimens were irradiated (with 0, 20, 40, and 70 Gy radiation doses, respectively) and sectioned to perform an attenuated total reflection-Fourier transform IR spectroscopy assay (ATR-FTIR) and the Vickers microhardness (VHN) test to conduct a biochemical and biomechanical evaluation of the tissues. Regarding the adhesive properties, restored enamel and dentin specimens exposed to the same radiation doses were submitted to microshear bond strength (μSBS) tests for enamel in immediate time (IM) and to microtensile bond strength (μTBS) tests after for IM and 12-month (12 M) period of time, Mann–Whitney U tests were implemented, using the ATR-FTIR data for significant differences (α \u3c 0.05), and three- and two-way analyses of variance, along with post-testing, were performed on the μTBS and μSBS data (MPa), respectively (Tukey post hoc test at α = 0.05). Results: The ATR-FTIR results showed a significant decrease (p Conclusions: It is possible to conclude that structural alterations of enamel and dentin are generated by all radiation doses, decreasing the microhardness of dental hard tissues and influencing bond strength over time, starting at 40 Gy radiation dose. The etch-and-rinse strategy demonstrates better adhesive performance but generates cohesive fractures in the enamel

Estrategia para la reactivacion de socios a traves de la Aplicacion de Cross Selling, en la Cooperativa de Ahorro y Credito Abamcoop Ltda.

84 p.En la Cooperativa Abamcoop Ltda., donde se desarrolla esta memoria presenta significativas deficiencias en lo que respecta a la participación de sus socios3, lo cual se refleja en el bajo monto del ahorro promedio de los socios (ver anexo Nº 9). Además la cooperativa no tiene información relevante sobre sus socios, con la cual pueda enfrentar de mejor manera las dificultades que se le presentan como entidad financiera. La baja fidelidad de los socios hacia la cooperativa, ha hecho que estos abandonen sus responsabilidades y dejen de entregar su dinero a la cooperativa. Esta situación es lo que impulsa el desarrollo de esta memoria, la que busca otorgar medidas que cambien esta situación, a través de la entrega de propuestas de estrategias. En los capítulos que componen esta memoria se realiza un análisis, para la utilización de la herramienta tecnológica CROSS SELLING, (o también llamada venta cruzada, la cual es detallada en el capitulo Marco Teórico).La elección de esta técnica es básicamente porque se enfoca a la fidelización de los socios, para poder conseguir una relación de confianza con ellos, y así conseguir que elijan los servicios ofrecidos. Para el desarrollo de esta memoria se utilizo la metodología CRISP-DM (Cross Industry Standard Process for Data Mining) para poder hacer un buen uso de la minería de datos, ya que esta nos fue fundamental para la determinación de los perfiles significativos de los socios. Cabe mencionar que la base de datos de donde fue obtenida la información para el estudio, entregada por la cooperativa, no se encontraba con una cantidad de información deseable para la entrega de resultados mas precisos y certeros. Siendo esto una gran limitante para obtener mejores resultados. 3 Se refiere a que el o los productos que no presentan movimiento en la cuenta capital “Estrategia para la reactivación de Socios a través de la Aplicación de Cross Selling, en la Cooperativa de Ahorro y crédito Abamcoop Ltda.” 10 Universidad de Talca Con la información obtenida en los resultados de esta memoria, logramos determinar ue el producto que prevalece en la mayoría de los socios es el de cuenta cuota de participación, la mayoría de los socios so

When a children’s literary jury imagines other children as potential readers: a case of collaborative research

In 2022, the Chilean literary award Premio Medalla Colibrí had a children’s jury for the first time. This article has been written by four researchers, two adults and two children, who participated in this process and then studied the experience. We did interviews with different people involved and an analysis based on the notion of wonder. Here, we present some reflections on the criteria used by the children’s jury and some findings that surprised us during the research process

Prospeccion en Conducta Vacacional del Profesional Aleman, con especial enfasis hacia el Turismo Rural en la Septima Region del Maule. Caso: Docentes y personal administrativo de la Universidad Georg-August de Gottingen, Alemania

145 p.La llegada de turistas extranjeros específicamente del continente europeo a la Región del Maule se ha incrementado a través de los años, constituyendo un mercado atractivo pero aun desconocido en cuanto a la conducta del turista, atributos buscados, entre otros aspectos; estudios realizados por SERNATUR han concluido que el turista alemán presenta un nivel de gasto atractivo para el sector turístico y que ha aumentado la demanda de turismo rural esta en desarrollo, por esta razón se necesita crear una oferta atractiva dirigida al mercado en estudio. En este contexto el capitulo I del estudio presenta los lineamientos que justifican y originan el estudio, el capitulo II presentan el marco referencial y conceptual que permite entender el desarrollo de la actividad turística, así Como los antecedentes del mercado en estudio, luego se presentan los objetivos planteados para el estudio lo que permite entregar una visión preliminar que facilita la comprensión de este. Esta prospección se enfoca al segmento de profesionales alemanes, para esto se trabajo con el caso de los profesionales de la universidad George August de Gottingen, Alemania. La metodología se compone de una etapa cualitativa llevada a cabo a través de entrevistas personales a alemanes residentes en Chile, en las cuales se consulto acerca del comportamiento vacacional, las entrevistas con empresarios turísticos de la región permitió determinar la calidad del servicio e infraestructura existente y la creación de un prototipo de producto para ser presentado con el instrumento de medición aplicado. Con la investigación cualitativa se estructuro un cuestionario que posteriormente fue traducido, piloteado y validado, este se aplico en los campus de la universidad alemana durante marzo y abril (2002). El análisis de la información recolectada fue analizada en el capitulo V, en el estudio se concluye que existe un alto interés por practicar turismo rural por parte del segmento profesional, y que existe una actitud positiva hacia el producto turístico del Maule, esto contrastado con la conducta actual del turista hace que este mercado sea atractivo de alcanzar, en términos económicos seria un aporte al ingreso regional dado la alta propensión a pagar que expresan, se propone promover un producto bien diseñado a través de Internet y catálogos de viajes distribuidos en agencias de viajes alemanas. Palabras claves del estudio: Turismo, Turismo Rural, Mercado alemán, Motivación, Percepción, Propensión de pago, Conducta, Intención, Atributos , Canal de compra, Medios de Información, Mezcla de Medios