5,784 research outputs found
Electronic instabilities in 3D arrays of small-diameter (3,3) carbon nanotubes
We investigate the electronic instabilities of the small-diameter (3,3)
carbon nanotubes by studying the low-energy perturbations of the normal
Luttinger liquid regime. The bosonization approach is adopted to deal exactly
with the interactions in the forward-scattering channels, while renormalization
group methods are used to analyze the low-energy instabilities. In this
respect, we take into account the competition between the effective e-e
interaction mediated by phonons and the Coulomb interaction in backscattering
and Umklapp channels. Moreover, we apply our analysis to relevant experimental
conditions where the nanotubes are assembled into large three-dimensional
arrays, which leads to an efficient screening of the Coulomb potential at small
momentum-transfer. We find that the destabilization of the normal metallic
behavior takes place through the onset of critical behavior in some of the two
charge stiffnesses that characterize the Luttinger liquid state. From a
physical point of view, this results in either a divergent compressibility or a
vanishing renormalized velocity for current excitations at the point of the
transition. We observe anyhow that this kind of critical behavior occurs
without the development of any appreciable sign of superconducting
correlations.Comment: 10 pages, 12 figure
Superconducting and pseudogap phases from scaling near a Van Hove singularity
We study the quantum corrections to the Fermi energy of a two-dimensional
electron system, showing that it is attracted towards the Van Hove singularity
for a certain range of doping levels. The scaling of the Fermi level allows to
cure the infrared singularities left in the BCS channel after renormalization
of the leading logarithm near the divergent density of states. A phase of
d-wave superconductivity arises beyond the point of optimal doping
corresponding to the peak of the superconducting instability. For lower doping
levels, the condensation of particle-hole pairs due to the nesting of the
saddle points takes over, leading to the opening of a gap for quasiparticles in
the neighborhood of the singular points.Comment: 4 pages, 6 Postscript figures, the physical discussion of the results
has been clarifie
Microscopic description of d-wave superconductivity by Van Hove nesting in the Hubbard model
We devise a computational approach to the Hubbard model that captures the
strong coupling dynamics arising when the Fermi level is at a Van Hove
singularity in the density of states. We rely on an approximate degeneracy
among the many-body states accounting for the main instabilities of the system
(antiferromagnetism, d-wave superconductivity). The Fermi line turns out to be
deformed in a manner consistent with the pinning of the Fermi level to the Van
Hove singularity. For a doping rate , the ground state is
characterized by d-wave symmetry, quasiparticles gapped only at the
saddle-points of the band, and a large peak at zero momentum in the d-wave
pairing correlations.Comment: 4 pages, 2 Postscript figure
Kinematics of electrons near a Van Hove singularity
A two dimensional electronic system, where the Fermi surface is close to a
Van Hove singularity, shows a variety of weak coupling instabilities, and it is
a convenient model to study the interplay between antiferromagnetism and
anisotropic superconductivity. We present a detailed analysis of the kinematics
of the electron scattering in this model. The similitudes, and differences,
between a standard Renormalization Group approach and previous work based on
parquet summations of log divergences are analyzed, with emphasis on the
underlying physical processes. General properties of the phase diagram are
discussed.Comment: 5 pages, 3 postscript figure
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Seasonal cycle of precipitation variability in South America on intraseasonal timescales
The seasonal cycle of the intraseasonal (IS) variability of precipitation in South America is described through the analysis of bandpass filtered outgoing longwave radiation (OLR) anomalies. The analysis is discriminated between short (10--30 days) and long (30--90 days) intraseasonal timescales. The seasonal cycle of the 30--90-day IS variability can be well described by the activity of first leading pattern (EOF1) computed separately for the wet season (October--April) and the dry season (May--September). In agreement with previous works, the EOF1 spatial distribution during the wet season is that of a dipole with centers of actions in the South Atlantic Convergence Zone (SACZ) and southeastern South America (SESA), while during the dry season, only the last center is discernible. In both seasons, the pattern is highly influenced by the activity of the Madden--Julian Oscillation (MJO). Moreover, EOF1 is related with a tropical zonal-wavenumber-1 structure superposed with coherent wave trains extended along the South Pacific during the wet season, while during the dry season the wavenumber-1 structure is not observed. The 10--30-day IS variability of OLR in South America can be well represented by the activity of the EOF1 computed through considering all seasons together, a dipole but with the stronger center located over SESA. While the convection activity at the tropical band does not seem to influence its activity, there are evidences that the atmospheric variability at subtropical-extratropical regions might have a role. Subpolar wavetrains are observed in the Pacific throughout the year and less intense during DJF, while a path of wave energy dispersion along a subtropical wavetrain also characterizes the other seasons. Further work is needed to identify the sources of the 10--30-day-IS variability in South America
Treatment with removable prosthesis in hypohidrotic ectodermal dysplasia : a clinical case
Ectodermal dysplasias form part of a wide range of syndromes presenting abnormal development of two or more tissues derived from the ectoderm. Hypohidrotic ectodermal dysplasia is a congenital syndrome, characterized by hypotrichosis (hair is sparse, fine and weak; anomalies in the skin and nails), hypohidrosis (due to the paucity of sweat glands which in turn gives rise to sweat disorders) and hypodontia (partial, and occasionally total, absence of primary and/or permanent dentition). A case of a child with hypohidrotic ectodermal dysplasia with oligodontia and marked resorption of the maxillary and mandibular alveolar ridges is presented. A prosthetic rehabilitation in the form of a removable acrylic prosthesis was made, achieving excellent esthetics, functionality and adaptation, thanks to which a considerable improvement in self-esteem has been obtained
Low agreement between modified-Schwartz and CKD-EPI eGFR in young adults: a retrospective longitudinal cohort study.
Background
While there is a great deal of research updating methods for estimating renal function, many of these methods are being developed in either adults with CKD or younger children. Currently, there is limited understanding of the agreement between the modified new bedside Schwartz estimated glomerular filtration rate (eGFR) formula and the adult CKD-EPI formula in adolescents and young adults (AYAs) with chronic kidney disease (CKD) measured longitudinally.
Methods
Longitudinal cohort study of 242 patients (10-30 years) with CKD, followed retrospectively in a single tertiary centre as they transitioned from the paediatric- to adult-focused settings. The study population came from a longitudinal cohort of AYAs undergoing healthcare transition at the STARx Program at the University of North Carolina, in the South-Eastern USA, from 2006 to 2015. We calculated and compared the eGFR using the new bedside Schwartz formula and the CKD-EPI eGFR. Measurements were repeated for each age in years. Agreement was tested using Bland & Altman analysis. Subgroup analysis was performed using the following age groups 10-15, 15-20, 20-25 and 25-30 years, glomerular and non-glomerular causes of CKD and height z-score.
Results
Using repeated measures, concordance between the new Schwartz and CKD-EPI eGFR was low at 0.74 (95% C.I. 0.67, 0.79) at the lowest age range of 10-15, 0.78 (95% C.I. 0.71, 0.84) at age 15-20, 0.80 (0.70, 0.87) at ages 20-25, and 0.82 (95% C.I. 0.70, 0.90) at age 25-30. Discordance was worse in males and largest in the 10-15 year-old age group, and in patients with stunted growth.
Conclusions
The Schwartz and CKD-EPI equations exhibit poor agreement in patients before and during the transition period with CKD-EPI consistently yielding higher eGFRs, especially in males. Further studies are required to determine the appropriate age for switching to the CKD-EPI equation after age 18
Utility of Gene Panels for the Diagnosis of Inborn Errors of Metabolism in a Metabolic Reference Center
Next-generation sequencing (NGS) technologies have been proposed as a first-line test for the diagnosis of inborn errors of metabolism (IEM), a group of genetically heterogeneous disorders with overlapping or nonspecific phenotypes. Over a 3-year period, we prospectively analyzed 311 pediatric patients with a suspected IEM using four targeted gene panels. The rate of positive diagnosis was 61.86% for intermediary metabolism defects, 32.84% for complex molecular defects, 19% for hypoglycemic/hyperglycemic events, and 17% for mitochondrial diseases, and a conclusive molecular diagnosis was established in 2-4 weeks. Forty-one patients for whom negative results were obtained with the mitochondrial diseases panel underwent subsequent analyses using the NeuroSeq panel, which groups all genes from the individual panels together with genes associated with neurological disorders (1870 genes in total). This achieved a diagnostic rate of 32%. We next evaluated the utility of a tool, Phenomizer, for differential diagnosis, and established a correlation between phenotype and molecular findings in 39.3% of patients. Finally, we evaluated the mutational architecture of the genes analyzed by determining z-scores, loss-of-function observed/expected upper bound fraction (LOEUF), and haploinsufficiency (HI) scores. In summary, targeted gene panels for specific groups of IEMs enabled rapid and effective diagnosis, which is critical for the therapeutic management of IEM patients.info:eu-repo/semantics/publishedVersio
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