Introducción del contenido de la orientación en Educación Primaria, en el área de Educación Física

Con el diseño de este trabajo, intento plasmar la orientación como un contenido relevante en Educación Primaria, trabajándolo desde el área de Educación Física. Es un tema muy significativo dentro del currículo, con un carácter interdisciplinar, fundamental para la formación integral del alumnado y necesario para poder desenvolverse en la vida cotidiana. Por ello, he considerado conveniente diseñar una unidad didáctica centrada en la orientación, tratando de enseñar a los alumnos los elementos primordiales, con el objetivo de desarrollar las habilidades y destrezas básicas necesarias para desplazarse por el entorno, trabajándolas tanto dentro como fuera del aula (escuela, medio natural).Grado en Educación Primari

Cancer Mortality in Older Mexican Individuals (2000 – 2010)

Objective: Given the trends in aging worldwide, in Mexico, we determined trends in adjusted mortality rates due to cancer and 11 cancer subtypes in older individuals (>65 years) from 2000 to 2010. Methods: For this retrospective study, we collected data on mortality due to cancer from the registries of the National Institute of Statistics and Geography. Adjusted rates were calculated with a direct method based on the world standard population. Trend analysis was performed with a linear regression of the natural logarithm of the adjusted rate, and trends were evaluated with the Student´s t test. Results: During the studied period, the cancer mortality rates significantly declined from 630.21 to 573.03 (per 100,000 inhabitants) in the overall population. Similar declines were observed in women (from 548.81 to 490.09) and men (from 726.03 to 672.94). Significant declines in mortality rates were observed across several cancer subtypes, including esophageal, gastric, colorectal-anal, liver-biliary, pancreatic, and tracheal-bronchial-lung cancers. Significant increases in mortality rates were observed in colorectal and breast cancer, but no changes were observed in mortality rates due to prostate, ovarian, bladder, and non-Hodgkin lymphoma cancers. Conclusion: Mortality due to cancer in older Mexicans was lower than that observed in developed countries, and it significantly declined over the study period. Men had higher mortality rates than women. The highest mortality rates were due to breast and prostate cancer subtypes in older individuals

Cancer Mortality in Older Mexican Individuals (2000 – 2010)

The article shows the trends of cancer mortality in older mexican individuals during the period from 2000 to 201

The importance of English for the Engineering and Medicine Schools´ Faculty´ at the University of El Salvador

English has become a worldwide language and there is no doubt about its importance in the present time. Many reasons can be mentioned to the spread of English, for example; the expansion of communication among people around the world through internet; also it is said that it is the language of science and technology, and its presence is remarked in medicine, engineering, education, tourism and in the entire world of business as well. The evolution that this society experiences especially related tote phenomenon of globalization requires having skilled professionals to face the challenges of this world. The English Language Revolution is intrinsically tied in with the progression of a technological global world and professional development. English has a big importance in most of the professional areas but it is necessary to say that there are some of them where English is considered as a fundamental tool of development. It can be said that English also helps professionals to develop themselves not only in their fields of work but also as a component in their professional growth. It is unfortunate that even though the clear evidence of the importance of the English Language is stated, there are still some professionals who do not show any interest at all about its learning. The perspective of non English-speaking professionals whose field the English Language is not demanded may not be concerned in the language. Based on the fact that learning English is essential, its use is present in almost all areas of knowledge and professional growing; practically, English is the Lingua Franca in this era of globalization; for that reason, nobody around the world ignores that English is a synonymous of progress and excellence in the professional development in a global higher education. The domain of English represents big opportunities for human beings in our society which demands not just one language to survive in any work field. In this sense, English plays a key role among professionals of education, especially, in Engineering and Medicine schools where the knowledge of second Language to develop academic activities is essential. The research project will be focused on the importance of English for the Engineering and Medicine schools ́ faculty ́ at the University of El Salvador, as well as, it describes and identifies the advantages of mastering English in the use of the technology

Mesoporous Silica Nanoparticles as a Potential Platform for Vaccine Development against Tuberculosis.

The increasing emergence of new strains of Mycobacterium tuberculosis (Mtb) highly resistant to antibiotics constitute a public health issue, since tuberculosis still constitutes the primary cause of death in the world due to bacterial infection. Mtb has been shown to produce membrane-derived extracellular vesicles (EVs) containing proteins responsible for modulating the pathological immune response after infection. These natural vesicles were considered a promising alternative to the development of novel vaccines. However, their use was compromised by the observed lack of reproducibility between preparations. In this work, with the aim of developing nanosystems mimicking the extracellular vesicles produced by Mtb, mesoporous silica nanoparticles (MSNs) have been used as nanocarriers of immunomodulatory and vesicle-associated proteins (Ag85B, LprG and LprA). These novel nanosystems have been designed and extensively characterized, demonstrating the e ectiveness of the covalent anchorage of the immunomodulatory proteins to the surface of the MSNs. The immunostimulatory capacity of the designed nanosystems has been demonstrated by measuring the levels of pro- (TNF) and anti-inflammatory (IL-10) cytokines in exposed macrophages. These results open a new possibility for the development of more complex nanosystems, including additional vesicle components or even antitubercular drugs, thus allowing for the combination of immunomodulatory and bactericidal e ects against Mtb.post-print2418 K

Complex regional pain syndrome (CRPS), a review

Complex regional pain syndrome is a chronic and painful condition that affects the quality of life of patients. It is usually triggered by a traumatic event of the soft tissues involving the nervous tissue. Although the factors that cause the syndrome are varied and not well known, different etiopathologic concepts have been proposed to explain the presence of this syndrome, such as autonomic dysfunction and changes in CNS plasticity, among others. The patient characteristically presents pain, sensory abnormalities, vasomotor disturbances in the skin, edema, changes in sweating, and motor alterations. The pain is associated with changes in the autonomic nervous system and has a distal predominance. Since there is no definitive diagnostic test, diagnosis is mainly based on a complete medical history and physical examination. Treatment is multidisciplinary and based on pain relief. Although in most cases evolution is favorable, rapid diagnosis and treatment are recommended to avoid dystrophic stage as much as possibl

Pro-vegetarian food patterns and cardiometabolic risk in the PREDIMED-Plus study: a cross-sectional baseline analysis

Purpose We explored the cross-sectional association between the adherence to three different provegetarian (PVG) food patterns defined as general (gPVG), healthful (hPVG) and unhealthful (uPVG), and the cardiometabolic risk in adults with metabolic syndrome (MetS) of the PREDIMED-Plus randomized intervention study. Methods We performed a cross-sectional analysis of baseline data from 6439 participants of the PREDIMED-Plus randomized intervention study. The gPVG food pattern was built by positively scoring plant foods (vegetables/fruits/legumes/grains/potatoes/nuts/olive oil) and negatively scoring, animal foods (meat and meat products/animal fats/eggs/fish and seafood/dairy products). The hPVG and uPVG were generated from the gPVG by adding four new food groups (tea and coffee/fruit juices/sugar-sweetened beverages/sweets and desserts), splitting grains and potatoes and scoring them differently. Multivariable-adjusted robust linear regression using MM-type estimator was used to assess the association between PVG food patterns and the standardized Metabolic Syndrome score (MetS z-score), a composed index that has been previously used to ascertain the cardiometabolic risk, adjusting for potential confounders. Results A higher adherence to the gPVG and hPVG was associated with lower cardiometabolic risk in multivariable models. The regression coefficients for 5th vs. 1st quintile were − 0.16 (95% CI: − 0.33 to 0.01) for gPVG (p trend: 0.015), and − 0.23 (95% CI: − 0.41 to − 0.05) for hPVG (p trend: 0.016). In contrast, a higher adherence to the uPVG was associated with higher cardiometabolic risk, 0.21 (95% CI: 0.04 to 0.38) (p trend: 0.019). Conclusion Higher adherence to gPVG and hPVG food patterns was generally associated with lower cardiovascular risk, whereas higher adherence to uPVG was associated to higher cardiovascular risk

The MORFO3D foot database

The final publication is available at Springer via http://dx.doi.org/10.1007/11492542_80A foot database comprising 3D foot shapes and footwear fitting reports of more than 300 participants is presented. It was primarily acquired to study footwear fitting, though it can also be used to analyse anatomical features of the foot. In fact, we present a technique for automatic detection of several foot anatomical landmarks, together with some empirical results.Work supported by the “Agència Valenciana de Ciència i Tecnologia” under grant GRUPOS03/031 and the Spanish projects DPI2001-0880-CO2-01 and DPI2001-0880-CO2-02.García Hernández, J.; Heras Barberá, SM.; Juan Císcar, A.; Paredes Palacios, R.; Nácher Rodríguez, B.; Alemany, S.; Alcántara, E.... (2005). The MORFO3D foot database. En Pattern Recognition and Image Analysis: Second Iberian Conference, IbPRIA 2005, Estoril, Portugal, June 7-9, 2005, Proceedings, Part II. Springer Verlag (Germany). 658-665. https://doi.org/10.1007/11492542_80S658665I-ware laboratory, http://www.i-ware.co.jp/Goonetilleke, R.S., Luximon, A.: Designing for comfort: a footwear application. In: Proceedings of the Computer-Aided Ergonomics and Safety Conference 2001, July 28-August 2 (2001) Plenary session paperNacher, B., Alcántara, E., Alemany, S., García-Hernández, J., Juan, A.: 3d foot digitalizing and its application to footwear fitting. In: Proc. of 3D Modelling (2004

Pro‑vegetarian food patterns and cardiometabolic risk in the PREDIMED‑Plus study: a cross‑sectional baseline analysis

Purpose We explored the cross-sectional association between the adherence to three diferent provegetarian (PVG) food patterns defned as general (gPVG), healthful (hPVG) and unhealthful (uPVG), and the cardiometabolic risk in adults with metabolic syndrome (MetS) of the PREDIMED-Plus randomized intervention study. Methods We performed a cross-sectional analysis of baseline data from 6439 participants of the PREDIMED-Plus rand omized intervention study. The gPVG food pattern was built by positively scoring plant foods (vegetables/fruits/legumes/ grains/potatoes/nuts/olive oil) and negatively scoring, animal foods (meat and meat products/animal fats/eggs/fsh and seafood/dairy products). The hPVG and uPVG were generated from the gPVG by adding four new food groups (tea and cof fee/fruit juices/sugar-sweetened beverages/sweets and desserts), splitting grains and potatoes and scoring them diferently. Multivariable-adjusted robust linear regression using MM-type estimator was used to assess the association between PVG food patterns and the standardized Metabolic Syndrome score (MetS z-score), a composed index that has been previously used to ascertain the cardiometabolic risk, adjusting for potential confounders. Results A higher adherence to the gPVG and hPVG was associated with lower cardiometabolic risk in multivariable models. The regression coefcients for 5th vs. 1st quintile were − 0.16 (95% CI: − 0.33 to 0.01) for gPVG (p trend: 0.015), and − 0.23 (95% CI: − 0.41 to − 0.05) for hPVG (p trend: 0.016). In contrast, a higher adherence to the uPVG was associated with higher cardiometabolic risk, 0.21 (95% CI: 0.04 to 0.38) (p trend: 0.019). Conclusion Higher adherence to gPVG and hPVG food patterns was generally associated with lower cardiovascular risk, whereas higher adherence to uPVG was associated to higher cardiovascular risk

Coffee Consumption and All-Cause, Cardiovascular, and Cancer Mortality in an Adult Mediterranean Population

We assessed the association between usual coffee consumption and all-cause, cardiovascular (CV), and cancer mortality in an adult population in Spain, taking into account both the amount and type of coffee consumed. We used baseline data on coffee consumption and other personal variables, and the number of deaths during an 18-year follow-up period, for 1567 participants aged 20 years and older from the Valencia Nutrition Study in Spain. Total, caffeinated, and decaffeinated coffee consumption was assessed using a validated food frequency questionnaire. Cox regression models were used to estimate adjusted hazard ratios (HRs) and 95% confidence intervals (CIs). During the 18-year follow-up period, 317 died; 115 due to CV disease and 82 due to cancer. Compared with no-consumption, the consumption of 1 cup per day and >1 cup per day of coffee was associated with a lower risk of all-cause mortality, HR = 0.73 (95% CI: 0.56–0.97) and HR 0.56 (95% CI: 0.41–0.77), respectively. A lower cancer mortality was observed among drinkers of more than 1 cup per day compared with nondrinkers, HR 0.41 (95% CI 0.20–0.86). Regarding the type of coffee, only the overall consumption of caffeinated coffee was associated with lower all-cause mortality at 12 and 18 years of follow-up, HR = 0.66 (95% CI:0.46–0.94) and HR = 0.59 (95% CI: 0.44–0.79), respectively. In conclusion, this study suggests that the moderate consumption of coffee, particularly caffeinated coffee (range 1–6.5 cups per day), is associated with a lower all-cause and cancer mortality after a long follow-up period. No significant association was found between coffee consumption and CVD mortality