Safety.Net: A Pilot Study on a Multi-Risk Internet Prevention Program

Many programs exist to prevent bullying and cyberbullying. Nevertheless, despite evidence of the numerous overlapping risks of the Internet, programs that jointly and adequately address large sets of risks are not presently described in the scientific literature. This study’s main objective was to assess the effectiveness of the Safety.net program in a pilot sample. This program prevents eight Internet risks: cyberbullying, sexting, online grooming, cyber dating abuse, problematic Internet use, nomophobia, Internet gaming disorder, and online gambling disorder. The Safety.net program comprises 16 sessions and 4 modules (digital skills, relational risks, dysfunctional risks, and change of attitudes and cognitions). Each session lasts one hour, but the program has a networked instructional design to recall previous content in later sessions. For its assessment, a pre/post-test repeated measures design with a control group and an intervention group was used. The study sample was 165 adolescents between 11 and 14 years old (M = 12.11, SD = 0.89). The intervention group demonstrated improvements compared to the control group concerning online grooming, problematic Internet use, Internet gaming disorder, and nomophobia. These results suggest that the Safety.net program is effective in preventing the increase of most of the assessed risks and that it reduces some of them with a small number of sessions.This research was funded by the Ministry of Economy, Industry and Competitiveness of Spain (RTI2018-094212-B-I00) and the International University of la Rioja (Project “Ciberpsicología (Trienio 2017–2020)”)

Problematic online gambling among adolescents: A systematic review about prevalence and related measurement issues

.Background and aims Despite its illegality among adolescents, online gambling is a common practice, which puts their mental health and well-being at serious risk. This systematic review summarises international scientific literature from the last 20 years on problematic online gambling among adolescents (11–21 years old) to determine its prevalence and to analyse related measurement issues. Methods The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed and a protocol was registered in the International Prospective Register of Systematic Reviews (PROSPERO, IC: CRD42020162932). Five academic databases were consulted, which resulted in an initial sample of 658 papers. Results Sixteen studies met the inclusion criteria for this review. All studies were cross-sectional and targeted students from elementary school, secondary school or university. Most followed a convenience sampling procedure. The primary measurement instruments used were the DSM-IV-MR-J and SOGS-RA. Between 0.77% and 57.5% of adolescents present some degree of problematic online gambling (problem, pathological or disordered) depending on the instruments used, the study samples and the timeframe analysed. Between 0.89% and 1% of adolescents exhibited an online gambling disorder. Discussion and conclusion There is a great heterogeneity in the methodology of the reviewed studies (samples, measurement instruments, cut-off points and criteria applied). The limited number of studies and the limited generalizability of their results suggest the need for further research and for development of specific instruments to assess different levels of problematic online gambling in representative samples of adolescents based on clinical ‘gold standard’ criteria and more accurate cut-off points.This research was funded by the Spanish Ministry of Economy, Industry and Competitiveness, RTI2018-094212-B-I00: (CIBER-AACC), and by the International University of La Rioja, Project “Cyberpsychology (Triennium 2017–2020)”

Empleo de Trefoil Factor-Family 3 (TFF3) en el pronóstico de pacientes diagnosticados con cáncer colorrectal

Peer reviewedUniversidad Autónoma de Madrid, Fundación para la Investigación Biomédica del Hospital Universitario de la Paz, Consejo Superior de Investigaciones CientíficasT3 Traducción de patente europe

Discovering optimal resource allocations for what-if scenarios using data-driven simulation

IntroductionData-driven simulation allows the discovery of process simulation models from event logs. The generated model can be used to simulate changes in the process configuration and to evaluate the expected performance of the processes before they are executed. Currently, these what-if scenarios are defined and assessed manually by the analysts. Besides the complexity of finding a suitable scenario for a desired performance, existing approaches simulate scenarios based on flow and data patterns leaving aside a resource-based analysis. Resources are critical on the process performance since they carry out costs, time, and quality.MethodsThis paper proposes a method to automate the discovery of optimal resource allocations to improve the performance of simulated what-if scenarios. We describe a model for individual resource allocation only to activities they fit. Then, we present how what-if scenarios are generated based on preference and collaboration allocation policies. The optimal resource allocations are discovered based on a user-defined multi-objective optimization function.Results and discussionThis method is integrated with a simulation environment to compare the trade-off in the performance of what-if scenarios when changing allocation policies. An experimental evaluation of multiple real-life and synthetic event logs shows that optimal resource allocations improve the simulation performance

Epidemiology of online sexual solicitation and interaction of minors with adults: A longitudinal study

Background: There have been very few longitudinal studies on online sexual solicitation and the online interaction between minors and adults. Still less evidence exists on the relationship of these problems with minors' Health-Related Quality of Life (HRQoL). Objective: This study aimed to analyze the point prevalence, period prevalence (prevalence over time) and incidence (new cases over time) of online sexual solicitation and interactions between minors and adults throughout three consecutive time periods and to compare the HRQoL among categories of victims (non-victims, new victims, ceased victims, intermittent victims, and stable victims). Participants and setting: The participants were 1029 Spanish students (43 % boys, 57 % girls), aged 12–15 years. Methods: A longitudinal study was conducted over a 13-month period, with measurements taken at three time points. Results: For sexual solicitation, the point prevalence was 11.3 % at wave 1 (W1), 11.9 % at wave 2 (W2), and 16.1 % at wave 3 (W3). For sexualized interactions, prevalence rates were 4.8 %, 7 %, and 7.1 %, respectively. However, throughout the study, almost 23 % of minors reported some sexual solicitation and 14 % reported some sexual interaction. In this same period of time, the incidence of new cases was 1 in 10. Being a victim during W1 meant that in W3, there was almost twice the risk of having a low HRQoL. In general, those who were not victims of either solicitation or sexualized interactions with adults presented better HRQoL than those who experienced victimization. Conclusions

Epidemiology of peer cybervictimization and its relationship with health-related quality of life in adolescents: A prospective study

Introduction: Research focused on the association between peer cybervictimization and declining health-related quality of life (HRQoL) is scarce. Currently, few longitudinal studies find an association between these phenomena, and none focus on cybervictimization profiles. The main objectives are: (1) to analyze the point and period prevalence, and incidence of cybervictimization profiles (uninvolved, new, ceased, intermittent, and stable cybervictims); (2) to study the relationship between cybervictimization and HRQoL over time; (3) to determine the longitudinal impact on the HRQoL of each type of profile. Methods: A prospective study was conducted in three waves over 13 months. A total of 1142 adolescents aged 11–18 years participated in all the waves (630 girls, 55.2%). Results: The prevalence of victimization for the three waves was 21.6% (Wave 1; W1), 23.5% (W2), and 19.6% (W3), respectively. The period prevalence was 41.3%, and the accumulated incidence was 25.1%. It was found that 24% of the participants were new victims, 5.9% were intermittent victims, and 6% were stable victims. Being a cybervictim at W1 poses a relative risk of 1.73 [1.29–2.32], that is, a twofold increased risk of presenting a low HRQoL 13 months later compared to those who are not cybervictims. Conclusion: One in four adolescents became a new cybervictim during the 13 months of the study. The adolescents who presented poorer HRQoL were the stable cybervictims

Solicitation and Sexualized Interactions of Minors with Adults: Prevalence, Overlap with Other Forms of Cybervictimization, and Relationship with Quality of Life

Sexual solicitation and sexualized interaction with minors by adults constitute one of the most pernicious risks of the Internet. Little is known about the age range in which this phenomenon is most prevalent or the relationship and overlap of this problem with other risks, such as peer-to-peer cybervictimization and cyber dating abuse. Additionally, little empirical evidence exists on whether the overlap between these types of online victimization affects health-related quality of life (HRQoL). This study aimed to: 1) analyze the prevalence of sexual solicitation and interaction according to sex and stage of adolescence; 2) relate this problem to other forms of online victimization (cybervictimization and cyber dating abuse); 3) analyze the overlap between these forms of online victimization and differences in HRQoL scores. A cross-sectional and analytical study with 3,578 adolescents (52.7% girls) aged between 10-15 years was carried out. Of the adolescents in the study sample, 12.6% (n = 448) had received sexual requests and 6.4% (n = 230) had interacted sexually with adults. Sexual solicitation was most common among girls in middle adolescence. Of the participants, 33.9% (n = 1,216) had been involved in some form of online victimization. Peer cybervictimization and cyber dating abuse were positively and significantly correlated with sexualized solicitation/interactions with adults. Victims with the overlapping of all three types of online victimization (2.7%, n = 98) presented the lowest HQRoL scores (p < .001).La solicitación e interacción sexual con menores por parte de adultos constituyen uno de los riesgos más perniciosos de Internet. Se sabe poco sobre la franja de edad en el que es más frecuente o sobre la relación y el solapamiento de este problema con otros riesgos, como la cibervictimización entre iguales y el abuso online en la pareja. Además, existen pocas evidencias empíricas sobre si el solapamiento entre estos tipos de victimización afecta a la calidad de vida relacionada con la salud (CVRS). Los objetivos de este estudio fueron: 1) analizar la prevalencia de la solicitación/interacción sexual en función del sexo y la etapa de la adolescencia, 2) relacionar esta problemática con la cibervictimización entre iguales y el abuso online en la pareja, 3) analizar el solapamiento entre estas formas de victimización online y sus diferencias en las puntaciones de CVRS. Se trata de un estudio transversal y analítico con 3,578 adolescentes (52.7% chicas) entre 10-15 años. El 12.6% (n = 448) habían recibido solicitaciones sexuales y el 6.4% (n = 230) había interactuado sexualmente con adultos. La solicitación sexual fue más frecuente en chicas en la adolescencia media. Un 33.9% (n = 1,216) había sufrido algún tipo de victimización online. La cibervictimización entre iguales y el abuso online en la pareja correlacionaron positiva y significativamente con solicitaciones/interacciones sexualizadas con adultos. Las víctimas que solaparon los tres tipos de victimización online (2.7%, n = 98) presentaron las puntuaciones de CVRS más bajas (p < .001)

Nanostructural changes in dentine caused by endodontic irrigants

Objective: To study nanostructural dentinal changes produced by endodontic irrigants. Study Design: Experimental study. Nanoindentations were performed on peritubular (PD) and intertubular dentine (ID) with an atomic force microscopy. Stiffness and adhesion force were determined before and after application of 5.25% sodium hypochlorite (NaOCl) and 17% ethylenediaminetetraacetic acid (EDTA). Normalized differences before and after treatment for stiffness and adhesion forces were calculated. A paired T-test was used to compare stiffnes and adhesion force before and after irrigants application. Results: After treatment with EDTA there was a 29.80% reduction in stiffness in ID and a 63.53% reduction in PD. Adhesion force was reduced by 21.22% and 8.21% respectively. After treatment with 5.25% NaOCI stiffness was reduced by 2.49% in ID and increased by 15.01% in PD. Adhesion force increased by 25.11% and 23.97% respectively. Conclusions: 17% EDTA reduced stiffness and adhesion force in ID and PD. Treatment with NaOCI at 5.25% had no significant effect on stiffness but did affect adhesion force in ID and PD