Review Essay: What Did the Cold War Teach Us?

In the late 1940s scholars and practitioners reached for the lessons learned from World Wars I and II to combat the growing threat posed by the Soviet Union. The United States established a free trade order to ensure Western prosperity, built peacetime alliances around the world to help contain Soviet power, and went to war to save South Korea and to demonstrate that aggression would not pay. For four decades Americans experienced a Cold War with the Soviet Union. The two superpowers engaged in a massive arms race and almost went to war over Berlin, Cuba, and the Middle East

PSYCHOLOGY AND INTERNATIONAL RELATIONS THEORY

Key Words error and bias, tradeoff reasoning, prospect theory, accountability pressures, internalization s Abstract Organized around several major theoretical traditions in international relations, this essay suggests which literature in psychology should be of greatest interest to different kinds of international relations scholars. New work in cognitive social psychology and behavioral decision theory simultaneously expands on and qualifies earlier error-and-bias portraits of the foreign policy maker, thereby enriching our understanding of internal divisions within the realist camp. Work on bounded rationality in competitive markets and mixed-motive games, as well as the literature on the power of human emotions to shape judgments of what represents an equitable allocation of scarce resources or a just resolution of conflicts of interest, can inform neo-institutionalist and constructivist theories. Developments in cross-cultural social psychology shed light on constructivist arguments about the creation and maintenance of international social order that typically rest on assumptions about decision making that are qualitatively different from realist and institutionalist approaches to world politics

Outbreak of Mycobacterium chelonae Infection Associated with Tattoo Ink

Background In January 2012, on the basis of an initial report from a dermatologist, we began to investigate an outbreak of tattoo-associated Mycobacterium chelonae skin and softtissue infections in Rochester, New York. The main goals were to identify the extent, cause, and form of transmission of the outbreak and to prevent further cases of infection. Methods We analyzed data from structured interviews with the patients, histopathological testing of skin-biopsy specimens, acid-fast bacilli smears, and microbial cultures and antimicrobial susceptibility testing. We also performed DNA sequencing, pulsed-field gel electrophoresis (PFGE), cultures of the ink and ingredients used in the preparation and packaging of the ink, assessment of source water and faucets at tattoo parlors, and investigation of the ink manufacturer. Results Between October and December 2011, a persistent, raised, erythematous rash in the tattoo area developed in 19 persons (13 men and 6 women) within 3 weeks after they received a tattoo from a single artist who used premixed gray ink; the highest occurrence of tattooing and rash onset was in November (accounting for 15 and 12 patients, respectively). The average age of the patients was 35 years (range, 18 to 48). Skin-biopsy specimens, obtained from 17 patients, showed abnormalities in all 17, with M. chelonae isolated from 14 and confirmed by means of DNA sequencing. PFGE analysis showed indistinguishable patterns in 11 clinical isolates and one of three unopened bottles of premixed ink. Eighteen of the 19 patients were treated with appropriate antibiotics, and their condition improved. Conclusions The premixed ink was the common source of infection in this outbreak. These findings led to a recall by the manufacturer

Activating mutations of the GNAQ gene: a frequent event in primary melanocytic neoplasms of the central nervous system

Primary melanocytic neoplasms of the central nervous system (CNS) are uncommon neoplasms derived from melanocytes that normally can be found in the leptomeninges. They cover a spectrum of malignancy grades ranging from low-grade melanocytomas to lesions of intermediate malignancy and overtly malignant melanomas. Characteristic genetic alterations in this group of neoplasms have not yet been identified. Using direct sequencing, we investigated 19 primary melanocytic lesions of the CNS (12 melanocytomas, 3 intermediate-grade melanocytomas, and 4 melanomas) for hotspot oncogenic mutations commonly found in melanocytic tumors of the skin (BRAF, NRAS, and HRAS genes) and uvea (GNAQ gene). Somatic mutations in the GNAQ gene at codon 209, resulting in constitutive activation of GNAQ, were detected in 7/19 (37%) tumors, including 6/12 melanocytomas, 0/3 intermediate-grade melanocytomas, and 1/4 melanomas. These GNAQ-mutated tumors were predominantly located around the spinal cord (6/7). One melanoma carried a BRAF point mutation that is frequently found in cutaneous melanomas (c.1799 T>A, p.V600E), raising the question whether this is a metastatic rather than a primary tumor. No HRAS or NRAS mutations were detected. We conclude that somatic mutations in the GNAQ gene at codon 209 are a frequent event in primary melanocytic neoplasms of the CNS. This finding provides new insight in the pathogenesis of these lesions and suggests that GNAQ-dependent mitogen-activated kinase signaling is a promising therapeutic target in these tumors. The prognostic and predictive value of GNAQ mutations in primary melanocytic lesions of the CNS needs to be determined in future studies

Europe and the political: from axiological monism to pluralistic dialogism

“The political” represents a moment in which actors recognise autonomy and equality as constitutive values in the agonistic search for appropriate open-ended political outcomes. The tutelary, pedagogical and disciplinary practices of the depoliticised European Union (EU) undermine the foundations of equality in diplomatic and political engagement between continental actors. The relationship becomes axiological, where issues are deemed to have been resolved through some sort of anterior pre-political arrangement. This is a type of ahistorical political monism that ultimately claims to speak for all of Europe. The return of “the political” allows a more generous and pluralistic politics to emerge based on genuine dialogical foundations in which self and other engage as equals and are mutually transformed by that engagement

Dissuasion in America's Russia Policy; Strategic Insights, v. 3 issue 10 (October 2004)

This article appeared in Strategic Insights, v.3 issue 10 (October 2004)PROBLEM BITSTREA

"The European Union, the post-communist world, and the shaping of national agendas"

[From the Introduction]. ...kin-state activism in Central and Eastern Europe has increased despite a substantive improvement of minority rights in most societies in this region and the fact that most Central and Eastern European societies are now either part of the EU (or expect to join in the near future). The purpose of our paper is to advance the understanding of this phenomenon. First, we outline the types of kin-state strategies that have emerged as popular in the region, with a particular focus on benefit laws and citizenship laws. We then turn to an analysis of the Hungarian case, which has been seemingly the most consistent and coherent virtual nationalism policy as well as the most controversial one, attracting a great degree of attention from policy-makers in the region, European officials, and scholars of nationalism. Finally, to gain further insight into the differences on the spectrum of virtual nationalism, we discuss the strategies pursued by Romania and Russia