Equine strangles: An update on disease control and prevention

Streptococcus equi spp. equi (SEE) causes a disease in horses commonly referred to as strangles. Carrier or reservoir equids are important for the maintenance of the bacteria between epizootics and the initiation of outbreaks on premises, they also make the control and prevention of the disease more difficult. Disease outbreaks are common in many countries, affecting negatively equine health and causing major economic losses to the equine industry. This review describes general aspects of the disease caused by SEE in horses (clinical signs, pathogenesis, epidemiology, treatment, complications) and then focuses on prevention, control and eradication mechanisms

Application of ERTS-1 data to integrated state planning in the state of Maryland

There are no author-identified significant results in this report

Interfacial mechanisms in active emulsions

Active emulsions, i.e., emulsions whose droplets perform self-propelled motion, are of tremendous interest for mimicking collective phenomena in biological populations such as phytoplankton and bacterial colonies, but also for experimentally studying rheology, pattern formation, and phase transitions in systems far from thermal equilibrium. For fuelling such systems, molecular processes involving the surfactants which stabilize the emulsions are a straightforward concept. We outline and compare two different types of reactions, one which chemically modifies the surfactant molecules, the other which transfers them into a different colloidal state. While in the first case symmetry breaking follows a standard linear instability, the second case turns out to be more complex. Depending on the dissolution pathway, there is either an intrinsically nonlinear instability, or no symmetry breaking at all (and hence no locomotion)

Effect on Antibiotics in High Fiber Diets on Performance of Growing-finishing Pigs

The majority of the pigs in the Upper Midwest are fed a corn-soybean meal base diet. However, alternative feed ingredients are widely used in some regions. The lower performance, daily gain and efficiency of gain that is sometimes observed when other ingredients are used is often associated with higher fiber content of the diet. The pig has little ability to utilize fibrous materials in the stomach and small intestine where most digestion of feed and absorption of nutrients take place. Microorganisms present in the cecum and large intestine do break down fiber to usable products, but it is assumed that relatively small amounts of these products are absorbed. The effect that antibiotics have on fiber utilization and microbial digestion in the lower digestive tract is largely unknown. The experiment reported herein was designed to evaluate pig performance as affected by fiber level, source of fiber and presence of antibiotics

The Effect of Selenium on Pigs of Different Hair Color

It has been suggested that levels of certain trace elements in hair may be associated with the dietary intake of the element. High levels of selenium in the diet have been shown to increase hair selenium in swine and also in cattle. The possibility that the degree of selenium toxicity is related to hair color has been proposed for cattle, horses and swine. This study was conducted to determine if storage of selenium in the hair of pigs varied with their color and also to determine if hair color was related to degree of selenium toxicity

Packing polydisperse colloids into crystals: when charge-dispersity matters

Monte Carlo simulations, fully constrained by experimental parameters, are found to agree well with a measured phase diagram of aqueous dispersions of nanoparticles with a moderate size polydispersity over a broad range of salt concentrations and volume fractions. Upon increasing volume fraction the colloids freeze first into coexisting compact solids then into a body centered cubic phase (bcc) before they melt into a glass forming liquid. The surprising stability of the bcc solid at high volume fractions and salt concentrations is explained by the interaction (charge) polydispersity and vibrational entropy

Hiding in Plain View: Colloidal Self-Assembly from Polydisperse Populations

We report small-angle x-ray scattering experiments on aqueous dispersions of colloidal silica with a broad monomodal size distribution (polydispersity, 14%; size, 8 nm). Over a range of volume fractions, the silica particles segregate to build first one, then two distinct sets of colloidal crystals. These dispersions thus demonstrate fractional crystallization and multiple-phase (bcc, Laves AB2, liquid) coexistence. Their remarkable ability to build complex crystal structures from a polydisperse population originates from the intermediate-range nature of interparticle forces, and it suggests routes for designing self-assembling colloidal crystals from the bottom up

A Mycobacterial Enzyme Essential for Cell Division Synergizes with Resuscitation-Promoting Factor

The final stage of bacterial cell division requires the activity of one or more enzymes capable of degrading the layers of peptidoglycan connecting two recently developed daughter cells. Although this is a key step in cell division and is required by all peptidoglycan-containing bacteria, little is known about how these potentially lethal enzymes are regulated. It is likely that regulation is mediated, at least partly, through protein–protein interactions. Two lytic transglycosylases of mycobacteria, known as resuscitation-promoting factor B and E (RpfB and RpfE), have previously been shown to interact with the peptidoglycan-hydrolyzing endopeptidase, Rpf-interacting protein A (RipA). These proteins may form a complex at the septum of dividing bacteria. To investigate the function of this potential complex, we generated depletion strains in M. smegmatis. Here we show that, while depletion of rpfB has no effect on viability or morphology, ripA depletion results in a marked decrease in growth and formation of long, branched chains. These growth and morphological defects could be functionally complemented by the M. tuberculosis ripA orthologue (rv1477), but not by another ripA-like orthologue (rv1478). Depletion of ripA also resulted in increased susceptibility to the cell wall–targeting β-lactams. Furthermore, we demonstrate that RipA has hydrolytic activity towards several cell wall substrates and synergizes with RpfB. These data reveal the unusual essentiality of a peptidoglycan hydrolase and suggest a novel protein–protein interaction as one way of regulating its activity

Effect of Bull Exposure on Reproductive Performance of First-Calf Heifers Bred by Natrual Service

Ninety-four spring calving, first-calf heifers were allotted to one of two treatment groups, control or bull exposed, to study the effect of bull exposure early postpartum on rebreeding performance when bred by natural service. Bull exposure early postpartum had no effect on pregnancy rate. However, bull exposure unexpectedly increased the subsequent calving interval by 9 days (P\u3c.05) and delayed the average calving date by 7 days (P\u3c.05). Under the conditions of this study in which heifers were in condition score 5 or better at calving and bred by natural service, bull exposure early postpartum did not improve reproductive performance

Protein Pattern Formation

Protein pattern formation is essential for the spatial organization of many intracellular processes like cell division, flagellum positioning, and chemotaxis. A prominent example of intracellular patterns are the oscillatory pole-to-pole oscillations of Min proteins in \textit{E. coli} whose biological function is to ensure precise cell division. Cell polarization, a prerequisite for processes such as stem cell differentiation and cell polarity in yeast, is also mediated by a diffusion-reaction process. More generally, these functional modules of cells serve as model systems for self-organization, one of the core principles of life. Under which conditions spatio-temporal patterns emerge, and how these patterns are regulated by biochemical and geometrical factors are major aspects of current research. Here we review recent theoretical and experimental advances in the field of intracellular pattern formation, focusing on general design principles and fundamental physical mechanisms.Comment: 17 pages, 14 figures, review articl