1,897 research outputs found
The Quaternary Bone Caves and Associated Sites at Wallingford, Jamaica
A group of caves associated with the sink of the One Eye River in St. Elizabeth Parish, Jamaica, have been the subject of numerous important palaeontological investigations beginning 1919. Unfortunately, considerable confusion has arisen in the literature through inadequate documentation of different sites. The caves of the immediate area are described and located, and their palaeontological significance is summarised in the light of recent taxonomic review and relevant geochronological evidence
An equatorial wind from the massive young stellar object S140 IRS 1
The discovery of the second equatorial ionized stellar wind from a massive
young stellar object is reported. High resolution radio continuum maps of S140
IRS 1 reveal a highly elongated source that is perpendicular to the larger
scale bipolar molecular outflow. This picture is confirmed by location of a
small scale monopolar near-IR reflection nebula at the base of the blueshifted
lobe. A second epoch of observations over a five year baseline show little
ordered outward proper motion of clumps as would have been expected for a jet.
A third epoch, taken only 50 days after the second, did show significant
changes in the radio morphology. These radio properties can all be understood
in the context of an equatorial wind driven by radiation pressure from the
central star and inner disc acting on the gas in the surface layers of the disc
as proposed by Drew et al. (1998). This equatorial wind system is briefly
compared with the one in S106IR, and contrasted with other massive young
stellar objects that drive ionized jets.Comment: 19 pages, 5 figures, accepted by ApJ, minor changes in light of
referees repor
UV Circular Polarisation in Star Formation Regions : The Origin of Homochirality?
Ultraviolet circularly polarised light has been suggested as the initial cause of the homochirality of organic molecules in terrestrial organisms, via enantiomeric selection of prebiotic molecules by asymmetric photolysis. We present a theoretical investigation of mechanisms by which ultraviolet circular polarisation may be produced in star formation regions. In the scenarios considered here, light scattering produces only a small percentage of net circular polarisation at any point in space, due to the forward throwing nature of the phase function in the ultraviolet. By contrast, dichroic extinction can produce a fairly high percentage of net circular polarisation (∼10%) and may therefore play a key role in producing an enantiomeric excessPeer reviewe
Iron biogeochemistry across marine systems progress from the past decade
Based on an international workshop (Gothenburg, 14–16 May 2008), this review article aims to combine interdisciplinary knowledge from coastal and open ocean research on iron biogeochemistry. The major scientific findings of the past decade are structured into sections on natural and artificial iron fertilization, iron inputs into coastal and estuarine systems, colloidal iron and organic matter, and biological processes. Potential effects of global climate change, particularly ocean acidification, on iron biogeochemistry are discussed. The findings are synthesized into recommendations for future research areas
Cometary Dust in the Debris Disks of HD 31648 and HD 163296: Two ``Baby'' beta Pics
The debris disks surrounding the pre-main sequence stars HD 31648 and HD
163296 were observed spectroscopically between 3 and 14 microns. Both possess a
silicate emission feature at 10 microns which resembles that of the star beta
Pictoris and those observed in solar system comets. The structure of the band
is consistent with a mixture of olivine and pyroxene material, plus an
underlying continuum of unspecified origin. The similarity in both size and
structure of the silicate band suggests that the material in these systems had
a processing history similar to that in our own solar system prior to the time
that the grains were incorporated into comets.Comment: 17 pages, AASTeX, 5 eps figures, accepted for publication in Ap.
The evolutionary status of the semiregular variable QYSge
Repeated spectroscopic observations made with the 6m telescope of yielded new
data on the radial-velocity variability of the anomalous yellow supergiant
QYSge. The strongest and most peculiar feature in its spectrum is the complex
profile of NaI D lines, which contains a narrow and a very wide emission
components. The wide emission component can be seen to extend from -170 to +120
km/s, and at its central part it is cut by an absorption feature, which, in
turn, is split into two subcomponents by a narrow (16km/s at r=2.5) emission
peak. An analysis of all the Vr values leads us to adopt for the star a
systemic velocity of Vr=-21.1 km/s, which corresponds to the position of the
narrow emission component of NaI. The locations of emission-line features of
NaI D lines are invariable, which point to their formation in regions that are
external to the supergiant's photosphere. Differential line shifts of about
10km/s are revealed. The absorption lines in the spectrum of QYSge have a
substantial width of FWHM~45 km/s. The method of model atmospheres is used to
determine the following parameters: Teff=6250K, lg g=2.0, and microturbulence
Vt=4.5km/s. The metallicity of the star is found to be somewhat higher than the
solar one with an average overabundance of iron-peak elements of [Met/H]=+0.20.
The star is found to be slightly overabundant in carbon and nitrogen,
[C/Fe]=+0.25, [N/Fe]=+0.27. The alpha-process elements Mg, Si, and Ca are
slightly overabundant [alpha/H]=+0.12. The strong sodium excess, [Na/Fe]=+0.75,
is likely to be due to the dredge-up of the matter processed in the NeNa cycle.
Heavy elements of the s-process are underabundant relative to the Sun. On the
whole, the observed properties of QYSge do not give grounds for including this
star into the group of RCrB or RVTau-type type objects.Comment: 29 pages, 8 figures, 4 tables; accepted by Astrophys. Bulleti
Selective VIP Receptor Agonists Facilitate Immune Transformation for Dopaminergic Neuroprotection in MPTP-Intoxicated Mice.
UNLABELLED: Vasoactive intestinal peptide (VIP) mediates a broad range of biological responses by activating two related receptors, VIP receptor 1 and 2 (VIPR1 and VIPR2). Although the use of native VIP facilitates neuroprotection, clinical application of the hormone is limited due to VIP\u27s rapid metabolism and inability to distinguish between VIPR1 and VIPR2 receptors. In addition, activation of both receptors by therapeutics may increase adverse secondary toxicities. Therefore, we developed metabolically stable and receptor-selective agonists for VIPR1 and VIPR2 to improve pharmacokinetic and pharmacodynamic therapeutic end points. Selective agonists were investigated for their abilities to protect mice against MPTP-induced neurodegeneration used to model Parkinson\u27s disease (PD). Survival of tyrosine hydroxylase neurons in the substantia nigra was determined by stereological tests after MPTP intoxication in mice pretreated with either VIPR1 or VIPR2 agonist or after adoptive transfer of splenic cell populations from agonist-treated mice administered to MPTP-intoxicated animals. Treatment with VIPR2 agonist or splenocytes from agonist-treated mice resulted in increased neuronal sparing. Immunohistochemical tests showed that agonist-treated mice displayed reductions in microglial responses, with the most pronounced effects in VIPR2 agonist-treated, MPTP-intoxicated mice. In parallel studies, we observed reductions in proinflammatory cytokine release that included IL-17A, IL-6, and IFN-γ and increases in GM-CSF transcripts in CD4(+) T cells recovered from VIPR2 agonist-treated animals. Moreover, a phenotypic shift of effector to regulatory T cells was observed. These results support the use of VIPR2-selective agonists as neuroprotective agents for PD treatment.
SIGNIFICANCE STATEMENT: Vasoactive intestinal peptide receptor 2 can elicit immune transformation in a model of Parkinson\u27s disease (PD). Such immunomodulatory capabilities can lead to neuroprotection by attenuating microglial activation and by slowing degradation of neuronal cell bodies and termini in MPTP-intoxicated mice. The protective mechanism arises from altering a Th1/Th2 immune cytokine response into an anti-inflammatory and neuronal sparing profile. These results are directly applicable for the development of novel PD therapies
Pulsations and Long-Term Light Variability of Three Candidates to Protoplanetary Nebulae
We present new photometric data and analysis of the long-duration UBV
photoelectric observations for three candidates to protoplanetary objects -
F-supergiants with IR-excesses located at large galactic latitudes, IRAS
18095+2704, IRAS 19386+0155, and IRAS 19500-1709. All three stars have revealed
quasiperiodic low-amplitude variabilities caused by pulsations observed against
the long-term trends of brightnesses. For IRAS 18095+2704=V887 Her we have
found a pulsation period of 109 days and a linear trend of brightness under the
constant colours if being averaged over the year timescale. The light curve of
IRAS 19386+0155=V1648 Aql over 2000-2008 can be approximated by a wave with a
main period of 102 days which is modulated by close frequency, with a period of
98 days, that results in brightness oscillations with a variable amplitude.
V1648 Aql has also shown synchronous reddening together with a persistent rise
of brightness in the V-band. IRAS 19500-1709=V5112 Sgr experiences irregular
pulsations with the periods of 39 and 47 days. The long-term component of the
variability of V5112 Sgr may be related to the binary character of this star.Comment: 11 pages, 6 figures, accepted for publication in Pis'ma Astron. Z
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