On the valuation of economic goods

The presented study includes an analysis of the category of “good” on the basis of philosophy and economics. Particular attention was paid here to the factors determining the monetary value (price) of an economic good. While achieving the assumed objective of the research, answers to the following questions were sought: What is the difference, therefore, in the interpretation of good as an axiological category and good which economics deals with? What is the basis for the valuation of goods which are the subject of economic analysis? While seeking answers to these questions, an attempt was made to justify the thesis according to which contemporary understanding of the way the market valuates goods is limited to accepting the price understood as a variable representing a kind of relationship set in a given time period.Publication of English-language versions of the volumes of the “Annales. Ethics in Economic Life” financed through contract no. 501/1/P-DUN/2017 from the funds of the Ministry of Science and Higher Education devoted to the promotion of scholarship

Everybody Talkin\u27 \u27Bout a Spoonful: The Blues, from America to England and Back

Though the blues are typically considered one of the few uniquely American musical styles, a group of British performers in the 1960s championed the blues to mainstream audiences on both sides of the Atlantic Ocean. This essay explores the journey of the blues from the Mississippi Delta to Chicago and then across the Atlantic to England. It examines the various changes the genre underwent throughout this journey as well as aspects of the blues that remained static. Utilizing the song Spoonful as a common thread between these locations, this essay details how changes in popular opinion , advancements in technology, and sheer force of will on the part of its devotees brought the blues to the forefront of 1 960s popular music scenes

An Exploration on Why Parents Choose Catholic Schools

“Though Many We Are One” is one of the mottos of a Catholic school system and is the foundational statement to what Catholic school stand for in the Diocese of the Midwest (pseudonym). My dissertation explores why parents choose alternative education in a Catholic schools. Catholic schools provide the student with the guidance and the ability to grow academically, spiritually, and emotionally. I analyzed the viewpoints of parents, administrators, and pastors within selected Catholic schools in the diocese to determine if there are similar foundational statements among multiple Catholic schools or if each school stands for something entirely different. Interviews and focus group discussions were used to understand parents’ perspectives. This study expands on Vygotsky’s theory that “the environment in which children grow up will influence how they think and what they think about” (p. 2). Students placed in an environment where a family are present in a child’s life, addressed by their name and their needs met, and the values and moral system taught in Catholic schools is an intricate part of the daily lessons taught. The overall themes include experiences of Catholic school parents, the importance of Catholic schools, and upholding the future of Catholic education

Rural Physician Assistant Job Satisfaction and Factors That Lead to Satisfaction

Background. PAs play a critical role in serving under-served rural communities. It will be of benefit to the rural communities in Minnesota to idenitfy what practice and community factors work to recruit and retain a high percentage of PAs to rural practice in Minnesota\u27 Methods A written questionnaire was mailed to PAs working in rural Minnesota who are members of MAPA, The survey explored community and practice aspects that contribute to job satisfaction. Results Ninety-two percent of respondents stated they were satisfied to very satisfied with their overall practice. Overall practice satisfaction was most strongly positively correlated with acknowledgment from patients and community members, physicians and nurses. Eighty-nine percent of respondents stated they were satisfied to very satisfied with overall community. Conclusions Rural Minnesota PAs indicated that satisfaction with practice and satisfaction with community were important co-contributors, therefore, suggesting that efforts toward rural community development are worthwhile and are important in promoting success in retaining local health care personnel. This study identified rural Minnesota PA overall practice satisfaction was most strongly influenced by acknowledgement from patients\u27 This evidence suggests the importance to educate patients, physicians, and other health care workers of the role, education, and experience of PAs

A mixed computational modelling and experimental approach to the interaction between gold nanoparticles and blood proteins

Upon arrival at the bloodstream, injected gold nanoparticles are covered with circulating plasma proteins, creating what is called a plasma corona. Its protein content is determined by the proteins’ affinity constants to the exposed surface of the nanoparticle. This work aims to propose an interaction mechanism between three plasma proteins and CALNN-functionalized nanoparticles via computational simulation and complementary experimental approach. Denaturing polyacrylamide gel electrophoresis determined the protein content of two human plasma samples, and helped in the characterization of the three most abundant blood proteins used in this study. Estimation of their electrostatic potential surfaces, silhouette areas, and diameters allowed the evaluation of the theoretical number of proteins forming a fully-covered nanoparticle. Seventeen transferrin molecules and eighteen albumin molecules with a side-on adsorption orientation were predicted to represent a monolayer adsorbome in a 20 nm gold nanoparticle. The dynamics of albumin adsorption to nanoparticles was studied through incubation-time assays on agarose gel electrophoresis, resulting in a stable protein corona starting from 7 h incubation time. The concentration ratio forming protein corona at the surface of nanoparticles was analysed through agarose gels electrophoretic mobility assays, revealing the formation of a full protein corona when a plateau in bionanoconjugates migration is achieved, resulting in protein coronas of [HSA]:[AuNP-CALNN] of 200:1 and 600:1 for [BPF]:[AuNP-CALNN] concentration ratios. Zeta-potential values were derived by relating agarose percentage with electrophoretic mobility of albumin bionanoconjugates, resulting in lower potential values for bionanoconjugates due to surface charge shielding of nanoparticles. Obtained ζ-potential values ranged from -26.05 up to -20.36 mV, forming colloid stable bionanoconjugates. Hydrodynamic radii of bionanoconjugates of albumin supported the formation of a monolayered and two-layered protein corona with increasing albumin:nanoparticle concentration ratios. Transferrin and fibrinogen showed increasing hydrodynamic radii with increasing protein:nanoparticle concentration ratios; in which fibrinogen bionanoconjugates showed fibrinogen wrapping around the nanoparticle. Electrostatic potential surfaces and protein-ligand docking using nanoparticle’s capping agent CALNN was performed in order to predict possible adsorption sites of human albumin and transferrin

Sensory sensitivity as a link between concussive traumatic brain injury and PTSD.

Traumatic brain injury (TBI) is one of the most common injuries to military personnel, a population often exposed to stressful stimuli and emotional trauma. Changes in sensory processing after TBI might contribute to TBI-post traumatic stress disorder (PTSD) comorbidity. Combining an animal model of TBI with an animal model of emotional trauma, we reveal an interaction between auditory sensitivity after TBI and fear conditioning where 75 dB white noise alone evokes a phonophobia-like phenotype and when paired with footshocks, fear is robustly enhanced. TBI reduced neuronal activity in the hippocampus but increased activity in the ipsilateral lateral amygdala (LA) when exposed to white noise. The white noise effect in LA was driven by increased activity in neurons projecting from ipsilateral auditory thalamus (medial geniculate nucleus). These data suggest that altered sensory processing within subcortical sensory-emotional circuitry after TBI results in neutral stimuli adopting aversive properties with a corresponding impact on facilitating trauma memories and may contribute to TBI-PTSD comorbidity