Esuli russi a Napoli e Capri tra XIX e XX secolo: Nikolaj Prachov, Nikolaj Firsov, Aleksej Zolotarev. Nuovi materiali

In the present article some unpublished manuscripts preserved in Russian libraries and archives are presentedand examined: the cycle of “ocherki” Old Naples (1940), folkloristic sketches written by the painter Nikolai Prachov (1873-1950); Tales about Italy (1902), stories with a social background by the writer, journalist and translator Nikolai Firsov (1839-1917) and Twelve Novella of Capri (1913-1949), nostalgic novels about love and the “new life” of Russian exiles in Capri of the writer, historian and critic Aleksei Zolotarev (1879-1950). The analysis of these writings enriches the line of studies of the so-called “russkaja neapolitana”, widening the boundaries of the literary conventions of Naples and surroundings like “paradise vs hell”, created by writers, artists and travellers of Romanticism and Decadence

LITTLE THINGS in 3D: robust determination of the circular velocity of dwarf irregular galaxies

Dwarf Irregular galaxies (dIrrs) are the smallest stellar systems with extended HI discs. The study of the kinematics of such discs is a powerful tool to estimate the total matter distribution at these very small scales. In this work, we study the HI kinematics of 17 galaxies extracted from the `Local Irregulars That Trace Luminosity Extremes, The HI Nearby Galaxy Survey' (LITTLE THINGS). Our approach differs significantly from previous studies in that we directly fit 3D models (two spatial dimensions plus one spectral dimension) using the software $^\text{3D}$BAROLO, fully exploiting the information in the HI datacubes. For each galaxy we derive the geometric parameters of the HI disc (inclination and position angle), the radial distribution of the surface density, the velocity-dispersion ($\sigma_v$) profile and the rotation curve. The circular velocity (V$_{\text{c}}$), which traces directly the galactic potential, is then obtained by correcting the rotation curve for the asymmetric drift. As an initial application, we show that these dIrrs lie on a baryonic Tully-Fisher relation in excellent agreement with that seen on larger scales. The final products of this work are high-quality, ready-to-use kinematic data ($\textrm{V}_\textrm{c}$ and $\sigma_v$) that we make publicly available. These can be used to perform dynamical studies and improve our understanding of these low-mass galaxies.Comment: 36 pages, 28 figures, 2 tables. Submitted to MNRAS (revised version after the referee report). The final rotation curves can be downloaded from http://www.filippofraternali.com/styled-9/index.htm

Leucoreduction of blood components. an effective way to increase blood safety?

Over the past 30 years, it has been demonstrated that removal of white blood cells from blood components is effective in preventing some adverse reactions such as febrile non-haemolytic transfusion reactions, immunisation against human leucocyte antigens and human platelet antigens, and transmission of cytomegalovirus. In this review we discuss indications for leucoreduction and classify them into three categories: evidence-based indications for which the clinical efficacy is proven, indications based on the analysis of observational clinical studies with very consistent results and indications for which the clinical efficacy is partial or unproven

Human T-lymphotropic virus and transfusion safety. Does one size fit all?

Human T-cell leukemia viruses (HTLV-1 and HTLV-2) are associated with a variety of human diseases, including some severe ones. Transfusion transmission of HTLV through cellular blood components is undeniable. HTLV screening of blood donations became mandatory in different countries to improve the safety of blood supplies. In Japan and Europe, most HTLV-infected donors are HTLV-1 positive, whereas in the United States a higher prevalence of HTLV-2 is reported. Many industrialized countries have also introduced universal leukoreduction of blood components, and pathogen inactivation technologies might be another effective preventive strategy, especially if and when generalized to all blood cellular products. Considering all measures available to minimize HTLV blood transmission, the question is what would be the most suitable and costeffective strategy to ensure a high level of blood safety regarding these viruses, considering that there is no solution that can be deemed optimal for all countries

Human parvovirus B19 and blood product safety. A tale of twenty years of improvements

Parvovirus B19 (B19V), long known to be the causative agent of erythema infectiosum (fifth disease), is not a newly emerging agent. The aim of this review is to analyse the role played by this virus in compromising safety in transfusion medicine and the progressive measures to reduce the risks associated with the virus

Strategie di documentazione per la ricerca e la comunicazione archeologica. Il caso di Faragola (Foggia, Italia)

[ES] La tecnología nos ha permitido reflexionar sobre el proceso de documentación arqueológica mediante la introducción de importantes innovaciones en todas las fases de la investigación, de recuperación de datos para el análisis, la interpretación, la reconstrucción y la comunicación de los resultados. Hoy en día los equipos arqueológicos tienen acceso directo a las nuevas herramientas y métodos en el sitio, pero a menudo sin un objetivo claro y preciso; sin ninguna pretensión de presentar un modelo, el presente documento describe una serie de experimentos de campo, y reflexiones sobre la base de la creciente utilización de computadoras en las diferentes fases de nuestra investigación.[EN] Computer technology has allowed us to rethink the process of archaeological documentation by introducing important innovations in all phases of research, from recovery of data to analysis, interpretation, reconstruction and communication of results. Nowadays archaeological teams have direct access to new tools and methods on site, but often without a clear and precise purpose; the methodological chaos that reigns over the application of computer technology to the practice of archaeology is clearly visible. Without any pretense of presenting a model, this paper describes a series of field experiments conducted on Faragola site, and reflections based on the growing use of computers in the various phases of our researchDe Felice, G.; Sibilano, MG. (2010). Strategie di documentazione per la ricerca e la comunicazione archeologica. Il caso di Faragola (Foggia, Italia). Virtual Archaeology Review. 1(2):95-99. https://doi.org/10.4995/var.2010.4696OJS959912BARCELÒ J. A. (2000): "Visualizing what might be. An introduction to Virtual Reality techniques in archaeology", in BARCELÒ J. A., FORTE M., SANDERS D. H. (eds.) Virtual Reality in Archaeology, Oxford, pp. 9-35.BARCELÒ, J. A. (2001): "Virtual reality for archaeological explanation. Beyond "picturesque reconstruction", in Archeologia e Calcolatori, 12, pp. 221-244.BARCELÒ, J. A., DE CASTRO, O., TRAVET, D., VICENTE, O. (2003): "A 3D model of an archaeological excavation", in DOERR M., SARRIS A. (eds.) The digital heritage of archaeology, Proceedings of the 30th CAA conference (Heraklion, Crete, April 2002), Heraklion, pp. 85-89.CARVER, M. O. H. (1990): "Digging for data: archaeological approaches to data definition, acquisition and analysis", in FRANCOVICH R., MANACORDA D. (eds.): Lo scavo archeologico. Dalla diagnosi all'edizione, III Ciclo di lezioni sulla ricerca applicata in archeologia, Certosa di Pontignano (Siena, 6-18 novembre 1989), Firenze, pp. 45-120.D'ANDREA, A. (2006): Documentazione archeologica, standard e trattamento informatico, Budapest.DE FELICE, G. (2008): "Il progetto Itinera. Ricerca e comunicazione attraverso nuovi metodi di documentazione archeologica" in DE FELICE G., SIBILANO. G., VOLPE G. (eds.) L'informatica e il metodo della stratigrafia. Atti del Workshop Digitalizzare la pesantezza (Foggia 6-7 giugno 2008), Bari, pp. 13-24.DE FELICE, G., SIBILANO, G., VOLPE, G. (2008): "Ripensare la documentazione archeologica: nuovi percorsi per la ricerca e la comunicazione", in Archeologia e Calcolatori, 19, in press.DE FELICE, G., MANGIALARDI, N., SIBILANO, G., VOLPE, G. (2008): "Late Roman Villa at Faragola (Foggia, Italy). Laser scanner for a global documentation methodology during field research", in POSLUSCHNY A., LAMBERS K., HERZOG I. (eds.) Layers of perception, Proceedings of the 35th CAA conference (Berlin, April 2007), Bonn, on cd-rom.Forte M. (ed.) (2007): La villa di Livia, Un percorso di ricerca di archeologia virtuale, Roma.LOCK, G. (2003): Using computers in archaeology: towards virtual pasts, London-New York.MANACORDA, D. (2004): Prima lezione di archeologia, Roma-Bari.MANACORDA, D. (2008): Lezioni di archeologia, Roma-Bari.MEDRI, M. (2003): Manuale di rilievo archeologico, Roma-Bari.RYAN, N. (2001): "Documenting and validating virtual archaeology", in Archeologia e calcolatori, 12, pp. 245-273.SIBILANO, M. G. (2008): "Documentare lo scavo archeologico: nuove forme di comunicazione del metodo stratigrafico", in DE FELICE G., SIBILANO. G., VOLPE G. (eds.) L'informatica e il metodo della stratigrafia. Atti del Workshop Digitalizzare la pesantezza (Foggia 6-7 giugno 2008), Bari, 143-158.VOLPE, G. (2007): "L'archeologia "globale" per ascoltare la "storia totale" del paesaggio", in Sudest, 20, pp. 20-32.VOLPE, G., DE FELICE, G., TURCHIANO, M. (2005): "Faragola (Ascoli Satriano). Una residenza aristocratica tardoantica e un villaggio altomedievale nella Valle del Carapelle: primi dati", in VOLPE, G., TURCHIANO, M. (eds.), Paesaggi e insediamenti rurali in Italia meridionale fra Tardoantico e Altomedioevo. Atti del I Seminario sul Tardoantico e l'Altomedioevo in Italia meridionale (STAIM 1) (Foggia, 12-14 febbraio 2004), Bari, pp. 265-297.VOLPE, G., DE FELICE, G., TURCHIANO, M. 2006, "La villa tardoantica di Faragola (Ascoli Satriano) in Apulia", in ARCE, J., BROGIOLO, G. P., CHAVARRIA, A. (eds.): Villas tardoantiguas en el Occidente mediterraneo, in Anejos de Archivio Espanol de Arquelogia, XXXIX, Madrid, pp. 221-251

Emigration, Inner Emigration, Exile, Camp: the Common and the Specific in the Writer's Self-consciousness

Филологический класс, Issue № 1 (55), Pages 175-17

Convalescent plasma. New evidence for an old therapeutic tool?

Passive immunisation for the prevention and treatment of human infectious diseases can be traced back to the 20th century. The recent Ebola virus outbreak in West Africa has turned the spotlight onto the possible use of convalescent whole blood and convalescent plasma in the treatment of infectious diseases because they are the only therapeutic strategy available in some cases, given the unavailability of vaccines, drugs or other specific treatments. Convalescent blood products could be a valid option in the treatment/prophylaxis of several infectious diseases both in association with other drugs/preventive measures and as the only therapy when a specific treatment is not available. However, there are still some issues to consider in determining the advisability of implementing a large-scale convalescent plasma transfusion programm

A genome wide association study for backfat thickness in Italian Large White pigs highlights new regions affecting fat deposition including neuronal genes.

open9noBACKGROUND: Carcass fatness is an important trait in most pig breeding programs. Following market requests, breeding plans for fresh pork consumption are usually designed to reduce carcass fat content and increase lean meat deposition. However, the Italian pig industry is mainly devoted to the production of Protected Designation of Origin dry cured hams: pigs are slaughtered at around 160 kg of live weight and the breeding goal aims at maintaining fat coverage, measured as backfat thickness to avoid excessive desiccation of the hams. This objective has shaped the genetic pool of Italian heavy pig breeds for a few decades. In this study we applied a selective genotyping approach within a population of ~ 12,000 performance tested Italian Large White pigs. Within this population, we selectively genotyped 304 pigs with extreme and divergent backfat thickness estimated breeding value by the Illumina PorcineSNP60 BeadChip and performed a genome wide association study to identify loci associated to this trait. RESULTS: We identified 4 single nucleotide polymorphisms with P≤5.0E-07 and additional 119 ones with 5.0E-07<P≤5.0E-05. These markers were located throughout all chromosomes. The largest numbers were found on porcine chromosomes 6 and 9 (n=15), 4 (n=13), and 7 (n=12) while the most significant marker was located on chromosome 18. Twenty-two single nucleotide polymorphisms were in intronic regions of genes already recognized by the Pre-Ensembl Sscrofa10.2 assembly. Gene Ontology analysis indicated an enrichment of Gene Ontology terms associated with nervous system development and regulation in concordance with results of large genome wide association studies for human obesity. CONCLUSIONS: Further investigations are needed to evaluate the effects of the identified single nucleotide polymorphisms associated with backfat thickness on other traits as a pre-requisite for practical applications in breeding programs. Reported results could improve our understanding of the biology of fat metabolism and deposition that could also be relevant for other mammalian species including humans, confirming the role of neuronal genes on obesity.To June 10, 2013 the paper is labelled as "Highly accessed" on the BMC genomics website http://www.biomedcentral.com/1471-2164/13/583openFontanesi L;Schiavo G;Galimberti G;Calò DG;Scotti E;Martelli PL;Buttazzoni L;Casadio R;Russo VFontanesi L;Schiavo G;Galimberti G;Calò DG;Scotti E;Martelli PL;Buttazzoni L;Casadio R;Russo