Studio epidemiologico e di comorbidita' della fobia sociale nella medicina generale: standardizzazione degli strumenti e valutazione diagnostica nell'area di Padova

Dottorato di ricerca in scienze psichiatriche. A.a. 1993-94. Coordinatore M. Tansella. Supervisore L. PavanConsiglio Nazionale delle Ricerche - Biblioteca Centrale - P.le Aldo Moro, 7, Rome; Biblioteca Nazionale Centrale - P.za Cavalleggeri, 1, Florence / CNR - Consiglio Nazionale delle RichercheSIGLEITItal

Personality and duodenal ulcer response to antisecretory treatment

Two groups of duodenal ulcer (DU) patients, responders and nonresponders, have been compared in order to verify if psychological factors are linked to relapse. Responders are defined as those patients who on endoscopy did not present proven relapse during treatment with maintenance doses of antisecretory drugs (cimetidine 400 mg/day, ranitidine 150 mg/day, pirenzepine 50 mg/day) for a period of 12 months after healing of the lesion. Nonresponders were all patients presenting with at least one relapse during treatment with antisecretory drugs. One hundred and twelve DU patients (81 responders, 31 nonresponders) were examined with the Cattell 16 Personality Factors Questionnaire (16PF) form C. There were no significant differences between the two groups for age, sex, duration of illness and type of drug treatment. The 16 PF scores of responders and nonresponders were not statistically different except in the case of factor E (dominance), in which the nonresponder subjects scored higher than responder subjects (p < 0.01). However, when the significance level was corrected for the number of variables involved, the above finding is not considered to be meaningful. © 1987 S. Karger AG, Basel

Risk factors for suicide behaviors in the observational schizophrenia outpatient health outcomes (SOHO) study

<p>Abstract</p> <p>Background</p> <p>To identify risk factors for suicide using data from a large, 3-year, multinational follow-up study of schizophrenia (SOHO study).</p> <p>Methods</p> <p>Baseline characteristics of 8,871 adult patients with schizophrenia were included in a logistic regression post-hoc analysis comparing patients who attempted and/or committed suicide during the study with those who did not.</p> <p>Results</p> <p>384 (4.3%) patients attempted or committed suicide. Completed suicides were 27 (0.3%). The significant risk factors for suicide behaviors were previous suicidality, depressive symptoms, prolactin-related adverse events, male gender and history of hospitalization for schizophrenia.</p> <p>Conclusions</p> <p>In view of the observational design of the study and the post-hoc nature of the analysis, the identified risk factors should be confirmed by ad-hoc specifically designed studies.</p